keyword
https://read.qxmd.com/read/38809601/superb-silk-hydrogels-with-high-adaptability-bioactivity-and-versatility-enabled-by-photo-cross-linking
#1
JOURNAL ARTICLE
Renyan Huang, Jiahui Hua, Min Ru, Meng Yu, Lu Wang, Ying Huang, Shuqin Yan, Qiang Zhang, Weilin Xu
The exceptional biocompatibility and adaptability of hydrogels have garnered significant interest in the biomedical field for the fabrication of biomedical devices. However, conventional synthetic hydrogels still exhibit relatively weak and fragile properties. Drawing inspiration from the photosynthesis process, we developed a facile approach to achieve a harmonious combination of superior mechanical properties and efficient preparation of silk fibroin hydrogel through photo-cross-linking technology, accomplished within 60 s...
May 29, 2024: ACS Nano
https://read.qxmd.com/read/38809353/glass-bead-system-to-study-mycotoxin-production-of-aspergillus-spp-on-corn-and-rice-starches
#2
JOURNAL ARTICLE
Katalin Inotai, Ildikó Bata-Vidács, Ákos Tóth, Judit Kosztik, Mónika Varga, András Szekeres, István Nagy, István Nagy, Csaba Dobolyi, Mária Mörtl, András Székács, József Kukolya
Mycotoxin production by aflatoxin B1 (AFB1) -producing Aspergillus flavus Zt41 and sterigmatocystin (ST) -hyperproducer Aspergillus creber 2663 mold strains on corn and rice starch, both of high purity and nearly identical amylose-amylopectin composition, as the only source of carbon, was studied. Scanning electron microscopy revealed average starch particle sizes of 4.54 ± 0.635 µm and 10.9 ± 2.78 µm, corresponding to surface area to volume ratios of 127 1/µm for rice starch and 0...
May 29, 2024: Applied Microbiology and Biotechnology
https://read.qxmd.com/read/38808183/the-volar-cortical-hinge-an-independent-risk-factor-for-distal-radius-fracture-displacement
#3
JOURNAL ARTICLE
Justin S Mathews, Tanushk L B Martyn, Kelsey S Rao, Simon B M MacLean
Background  Displaced distal radius fractures are prone to redisplacement after manipulation. This can result in the need for delayed surgery. Several criteria have been studied to predict the likelihood of redisplacement. We hypothesized that reduction in the volar cortex would be an additional predictive factor. Purpose  The aim of this study was to assess whether the quality of the volar cortex reduction predicts the subsequent need for further intervention (surgery or remanipulation). As a secondary outcome, we assessed whether the quality of the reduction predicts the rate of malunion...
June 2024: Journal of Wrist Surgery
https://read.qxmd.com/read/38807795/fosmanogepix-the-novel-anti-fungal-agent-s-comprehensive-review-of-in-vitro-in-vivo-and-current-insights-from-advancing-clinical-trials
#4
REVIEW
Ali Almajid, Ali Bazroon, Hashim M Al-Awami, Hassan Albarbari, Ibrahim Alqahtani, Rehab Almutairi, Abbas Alsuwayj, Faiza Alahmadi, Jinan Aljawad, Razan Alnimer, Nawal Asiri, Shouq Alajlani, Reem Alshelali, Yamama Aljishi
Fosmanogepix, a prodrug of Manogepix (MGX), is a groundbreaking antifungal agent with broad-spectrum activity against yeasts, including Cryptococcus and Candida , as well as molds. It exhibits effectiveness against drug-resistant strains, such as Candida strains resistant to echinocandins and Aspergillus strains resistant to azoles. Furthermore, fosmanogepix shows activity against pathogens that typically resist other classes of drugs, such as Scedosporium , Lomentospora prolificans , and Fusarium , although its efficacy against Mucorales varies...
April 2024: Curēus
https://read.qxmd.com/read/38807367/plant-triterpenoid-saponins-function-as-susceptibility-factors-to-promote-the-pathogenicity-of-botrytis-cinerea
#5
JOURNAL ARTICLE
Francisco J Escaray, Amelia Felipo-Benavent, Cristian J Antonelli, Begoña Balaguer, Maria Pilar Lopez-Gresa, Pablo Vera
The gray mold fungus Botrytis cinerea is a necrotrophic pathogen that causes diseases in hundreds of plant species, including high-value crops. This polyxenous nature and pathogenic success are due to its ability to perceive host signals on its favor. We found that laticifer cells of Euphorbia lathyris are a source of susceptibility (S) factors required by B. cinerea to generate disease. Consequently, poor-in-latex (pil) mutants, which lack laticifer cells, show full resistance to this pathogen, whereas lot-of-latex (lol) mutants, which produces more laticifer cells, are hypersusceptible...
May 27, 2024: Molecular Plant
https://read.qxmd.com/read/38806161/the-technique-and-material-used-to-join-transfers-affect-the-accuracy-and-final-fit-of-implant-supported-prostheses-in-vitro-study
#6
JOURNAL ARTICLE
Guilherme de Aguiar Mariotto, Anna Caroliny Detogni, Monica Cavalheiro Persh, Mário Alexandre Coelho Sinhoreti, Veridiana Camilotti, Márcio José Mendonça
OBJECTIVES:  This study evaluated the linear dimensional change of polymerization of three materials and two techniques of the union of molding transfers for implant-supported prostheses used in the open-tray technique. MATERIALS AND METHODS:  A nylon maxilla-shaped matrix was made, two osseous integrated implants were installed, and, over these two, straight conical mini-pillars were installed. Open-tray impression transfers were attached to the mini-pillars, and a silicone guide was made to standardize the connections between the transfers...
May 28, 2024: European Journal of Dentistry
https://read.qxmd.com/read/38805495/the-statistical-and-dynamic-modeling-of-the-first-part-of-the-2013-2014-euromaidan-protests-in-ukraine-the-revolution-of-dignity-and-preceding-times
#7
JOURNAL ARTICLE
Yassin Bahid, Olga Kutsenko, Nancy Rodríguez, David White
Ukraine's tug-of-war between Russia and the West has had significant and lasting consequences for the country. In 2013, Viktor Yanukovych, the Ukrainian president aligned with Russia, opted against signing an association agreement with the European Union. This agreement aimed to facilitate trade and travel between the EU and Ukraine. This decision sparked widespread protests that coalesced in Kyiv's Maidan Square, eventually becoming known as the Euromaidan protests. In this study, we analyze the protest data from 2013, sourced from Ukraine's Center for Social and Labor Research...
2024: PloS One
https://read.qxmd.com/read/38803074/first-report-of-botrytis-cinerea-causing-grey-mold-on-corydalis-yanhusuo-in-panan-china
#8
JOURNAL ARTICLE
Dan Zhao, Chang Gui Yang, Cheng-Hong Xiao, ZhiKun Wu, Shaofeng Ren, Ye Yang
Yanhusuo (Corydalis yanhusuo (Y. H. Chou & Chun C. Hsu) W. T. Wang ex Z.Y. Su & C.Y. Wu), a perennial herbaceous plant of the Papaveraceae family and genus Corydalis, is also known as Yuanhu and used as medicine by its tuberous roots. It is mainly planted in Zhejiang, Jiangsu and Anhui provinces of China, with the best quality produced in Panan County of Zhejiang province. Yanhusuo has the effects of promoting blood circulation, invigorating the flow of qi and relieving pain, and is widely used in Chinese traditional medicines...
May 27, 2024: Plant Disease
https://read.qxmd.com/read/38801991/invasive-aspergillosis-in-liver-transplant-recipients-in-the-current-era
#9
JOURNAL ARTICLE
Muneyoshi Kimura, Matteo Rinaldi, Sagar Kothari, Maddalena Giannella, Shweta Anjan, Yoichiro Natori, Pakpoom Phoompoung, Emily Gault, Jonathan Hand, Matilde D'Asaro, Dionysios Neofytos, Nicolas J Mueller, Andreas E Kremer, Tereza Rojko, Marija Ribnikar, Fernanda P Silveira, Joshua Kohl, Angela Cano, Julian Torre-Cisneros, Rafael San-Juan, Jose Maria Aguado, Armaghan-E-Rehman Mansoor, Ige Abraham George, Alessandra Mularoni, Giovanna Russelli, Me-Linh Luong, Yamama A AlJishi, Maram N AlJishi, Bassem Hamandi, Nazia Selzner, Shahid Husain
Invasive aspergillosis (IA) is a rare but fatal disease among liver transplant recipients (LiTRs). We performed a multi-center 1:2 case-control study comparing LiTRs diagnosed with proven/probable IA and controls with no invasive fungal infection. We included 62 IA cases and 124 matched controls. Disseminated infection occurred only in eight cases (13%). 12-week all-cause mortality of IA was 37%. In multivariate analyses, systemic antibiotics usage (adjusted odds ratio [aOR], 4.74; p=0.03) and history of pneumonia (aOR, 48...
May 25, 2024: American Journal of Transplantation
https://read.qxmd.com/read/38798279/distributional-characteristics-analysis-of-allergens-in-patients-with-allergic-rhinitis-in-southern-fujian-province-china
#10
JOURNAL ARTICLE
Jingjing He, Jing Gao, Yan Zhao, Shuai Chen
BACKGROUND: Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa. However, few studies focus on the distributional characteristics of allergens in AR patients in Southern Fujian Province, China. METHODS: A skin prick test (SPT) was performed and eight common allergens including Dermatophagoides farinae ( Df), Dermatophagoides pteronyssinus ( Dpt ), weeds, animal dander, molds, cockroaches, and mangoes were chosen. RESULTS: The positive reactions rate to the allergens was 65...
2024: Journal of Asthma and Allergy
https://read.qxmd.com/read/38797101/effect-of-3d-printing-and-traditional-molding-on-phenolic-compounds-and-antioxidant-activity-in-steamed-bread
#11
JOURNAL ARTICLE
Shu Ma, Yanru Bao, Ming Xu, Xiuzhu Yu, Hao Jiang
The production process of fermented black wheat steamed bread is closely related to the overall quality and nutritional content. In this study, we investigated the accuracy, product texture profile and antioxidant activity of fermented black wheat steamed bread samples produced by piston and spiral three-dimensional (3D) printers. The steaming process generally increased the total phenolic content and flavonoid content of the samples. The spiral 3D printer obtained samples with higher accuracy, total phenolic content up to 1960...
May 25, 2024: Food Chemistry
https://read.qxmd.com/read/38795655/effect-of-photostimulation-through-red-led-light-radiation-on-natural-fermentation-of-table-olives-an-innovative-case-study-with-negrinha-the-freixo-variety
#12
JOURNAL ARTICLE
Fátima Martins, Elsa Ramalhosa, Nuno Rodrigues, José Alberto Pereira, Paula Baptista, Maria Filomena F Barreiro, Pedro J L Crugeira
In this study, for the first time, red LED light radiation was applied to the fermentation process of table olives using the Negrinha de Freixo variety. Photostimulation using LED light emission (630 ± 10 nm) is proposed to shorten and speed up this stage and reduce time to market. Several physical-chemical characteristics and microorganisms (total microbial count of mesophilic aerobic, molds, yeasts, and lactic acid bacteria) and their sequence during fermentation were monitored. The fermentation occurred for 122 days, with two irradiation periods for red LED light...
May 21, 2024: Journal of Photochemistry and Photobiology. B, Biology
https://read.qxmd.com/read/38795351/protocol-for-the-microinjection-of-free-fatty-acids-and-triacylglycerol-in-zebrafish-embryos
#13
JOURNAL ARTICLE
Bridget Konadu, Carol K Cox, Yann Gibert
During development, the zebrafish embryo relies on its yolk sac as a nutrient source. Here, we present a protocol for modifying the free fatty acid (FFA) and triacylglycerol (TAG) content of the zebrafish yolk sac by microinjection. We describe steps for needle and injection mold preparation, FFA and TAG solution preparation, and microinjection. This protocol can elucidate how excesses of FFA and TAG affect development and modify the transcriptome of zebrafish embryos. For complete details on the use and execution of this protocol, please refer to Konadu et al...
May 24, 2024: STAR protocols
https://read.qxmd.com/read/38794610/numerical-simulation-of-mold-filling-of-polymeric-materials-with-friction-effect-during-hot-embossing-process-at-micro-scale
#14
JOURNAL ARTICLE
Faleh Rabhi, Gang Cheng, Thierry Barriere
The filling efficiency during the hot embossing process at micro scale is essential for micro-component replication. The presence of the unfilled area is often due to the inadequate behavior law applied to the embossed materials. This research consists of the identification of viscoplastic law (two-layer viscoplastic model) of polymers and the optimization of processing parameters. Mechanical tests have been performed for two polymers at 20 °C and 30 °C above their glass transition temperature. The viscoplastic parameters are characterized based on stress-strain curves from the compression tests...
May 16, 2024: Polymers
https://read.qxmd.com/read/38794609/polydimethylsiloxane-surface-modification-of-microfluidic-devices-for-blood-plasma-separation
#15
JOURNAL ARTICLE
Margarida Gonçalves, Inês Maia Gonçalves, Joel Borges, Vera Faustino, Delfim Soares, Filipe Vaz, Graça Minas, Rui Lima, Diana Pinho
Over the last decade, researchers have developed a variety of new analytical and clinical diagnostic devices. These devices are predominantly based on microfluidic technologies, where biological samples can be processed and manipulated for the collection and detection of important biomolecules. Polydimethylsiloxane (PDMS) is the most commonly used material in the fabrication of these microfluidic devices. However, it has a hydrophobic nature (contact angle with water of 110°), leading to poor wetting behavior and issues related to the mixing of fluids, difficulties in obtaining uniform coatings, and reduced efficiency in processes such as plasma separation and molecule detection (protein adsorption)...
May 16, 2024: Polymers
https://read.qxmd.com/read/38794579/an-enhanced-vacuum-assisted-resin-transfer-molding-process-and-its-pressure-effect-on-resin-infusion-behavior-and-composite-material-performance
#16
JOURNAL ARTICLE
Rulin Shen, Taizhi Liu, Hehua Liu, Xiangfu Zou, Yanling Gong, Haibo Guo
In this paper, an enhanced VARTM process is proposed and its pressure effect on resin infusion behavior and composite material performance is studied to reveal the control mechanism of the fiber volume fraction and void content. The molding is vacuumized during the resin injection stage while it is pressurized during the mold filling and curing stages via a VARTM pressure control system designed in this paper. Theoretical calculations and simulation methods are used to reveal the resin's in-plane, transverse, and three-dimensional flow patterns in multi-layer media...
May 13, 2024: Polymers
https://read.qxmd.com/read/38794538/valorization-of-winery-by-products-as-bio-fillers-for-biopolymer-based-composites
#17
JOURNAL ARTICLE
Filippo Biagi, Alberto Giubilini, Paolo Veronesi, Giovanni Nigro, Massimo Messori
Grape seeds (GS), wine lees (WL), and grape pomace (GP) are common winery by-products, used as bio-fillers in this research with two distinct biopolymer matrices-poly(butylene adipate- co -terephthalate) (PBAT) and polybutylene succinate (PBS)-to create fully bio-based composite materials. Each composite included at least 30 v% bio-filler, with a sample reaching 40 v%, as we sought to determine a composition that could be economically and environmentally effective as a substitute for a pure biopolymer matrix...
May 9, 2024: Polymers
https://read.qxmd.com/read/38793460/research-and-validation-of-cf-peek-based-truss-rod-crimping-and-pultruding-process-for-on-orbit-isoform-forming
#18
JOURNAL ARTICLE
Jiayong Yan, Peng Li, Chao Geng, Xuanyu Guo, Lixin Zhang
A crimping and pultruding forming process for truss rods using Carbon Fiber (CF)/Polyether-Ether-Ketone (PEEK) prepreg tape as the raw material is proposed to address the problem of continuous manufacturing of space trusses on orbit. The proposed process provides material rods for continuous truss manufacturing. Through numerical simulation and experimental verification, the effects of relevant parameters on the forming process are determined, an efficient method of rod curl pultrusion, in-rail, equal material forming is proposed, and the structural configuration of the rod curl pultrusion forming mold is determined...
May 16, 2024: Materials
https://read.qxmd.com/read/38793387/effect-of-chemical-treatments-on-the-mechanical-properties-of-jute-polyester-composites
#19
JOURNAL ARTICLE
André Luis Lima Flores, Agnė Kairytė, Jurga Šeputytė-Jucikė, Sylwia Makowska, Alessandra Lavoratti, Rafael de Avila Delucis, Sandro Campos Amico
Natural fiber composites have been extensively studied for structural applications, with recent exploration into their potential for various uses. This study investigates the impact of chemical treatments on the properties of Brazilian jute woven fabric/polyester resin composites. Sodium hydroxide, hydrogen peroxide, and peracetic acid were utilized to treat the jute fabrics, followed by resin transfer molding (RTM) to form the composites. Evaluation included water absorption, flexural strength, tensile strength, and short-beam strength...
May 14, 2024: Materials
https://read.qxmd.com/read/38793343/nanoimprinted-tio-2-metasurfaces-with-reduced-meta-atom-aspect-ratio-and-enhanced-performance-for-holographic-imaging
#20
JOURNAL ARTICLE
Kaiyu Zhang, Yuqi Lin, Yang Qiu, Xingyan Zhao, Shaonan Zheng, Yuan Dong, Qize Zhong, Ting Hu
Metasurface holograms, with the capability to manipulate spatial light amplitudes and phases, are considered next-generation solutions for holographic imaging. However, conventional fabrication approaches for meta-atoms are heavily dependent on electron-beam lithography (EBL), a technique known for its expensive and time-consuming nature. In this paper, a polarization-insensitive metasurface hologram is proposed using a cost-effective and rapid nanoimprinting method with titanium dioxide (TiO2 ) nanoparticle loaded polymer (NLP)...
May 11, 2024: Materials
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