Ping Sun, Yi Li, Yifei Li, Huan Ji, Ge Mang, Shuai Fu, Shuangquan Jiang, Stephen Choi, Xiaoqi Wang, Zhonghua Tong, Chao Wang, Fei Gao, Pingping Wan, Shuang Chen, You Li, Peng Zhao, Xiaoping Leng, Maomao Zhang, Jiawei Tian
AIMS: CD4+ T cells are activated during inflammatory dilated cardiomyopathy (iDCM) development to induce immunogenic responses that damage the myocardium. Low-intensity pulsed ultrasound (LIPUS), a novel physiotherapy for cardiovascular diseases, has recently been shown to modulate inflammatory responses. However, its efficacy in iDCM remains unknown. Here, we investigated whether LIPUS could improve the severity of iDCM by orchestrating immune responses and explored its therapeutic mechanisms...
May 2, 2024: Cardiovascular Research