I Lindström, P Hölttä, L Airaksinen, K Suuronen, S Suomela, H Suojalehto
BACKGROUND: The current knowledge about occupational allergic diseases among greenhouse workers is scant. AIMS: To describe greenhouse workers' occupational allergic diseases. METHODS: We identified 28 greenhouse workers with occupational allergic diseases in 2002-2020 by conducting a systematic search in the patient register of the Finnish Institute of Occupational Health. All the patients worked in tomato- or cucumber-growing greenhouses and showed immunoglobulin-E-mediated sensitization to occupational agents...
December 2, 2023: Occupational Medicine
Sylwia Smolinska, Florin-Dan Popescu, Elena Izquierdo, Darío Antolín-Amérigo, Oliver J Price, Alberto Alvarez-Perea, Ibon Eguíluz Gracia, Nikolaos G Papadopoulos, Oliver Pfaar, Filippo Fassio, Karin Hoffmann-Sommergruber, Stephanie Dramburg, Ioana Agache, Marek Jutel, Helen A Brough, João A Fonseca, Elizabeth Angier, Cristina Boccabella, Matteo Bonini, Audrey Dunn Galvin, Peter G Gibson, Radoslaw Gawlik, Farah Hannachi, Ömer Kalayci, Ludger Klimek, Rebecca Knibb, Paolo Matricardi, Tomás Chivato
Efficacious, effective and efficient communication between healthcare professionals (HCP) and patients is essential to achieve a successful therapeutic alliance. Telemedicine (TM) has been used for decades but during the COVID-19 pandemic its use has become widespread. This position paper aims to describe the terminology and most important forms of TM among HCP and patients and review the existing studies on the uses of TM for asthma and allergy. Besides, the advantages and risks of TM are discussed, concluding that TM application reduces costs and time for both, HCP and patients, but cannot completely replace face-to-face visits for physical examinations and certain tests that are critical in asthma and allergy...
December 1, 2023: Allergy
Meg O' Sullivan, Margaret Curtin, Rachel Flynn, Caoimhe Cronin, James O' Mahony, Juan Trujillo
Telehealth is an emerging approach that uses technology to provide healthcare remotely. Recent publications have outlined the importance of supporting the transition to self-management of adolescents with allergic conditions. However, no synthesis of the evidence base on the use and impact of telehealth interventions for this purpose has been conducted to date. This review achieves these aims, in addition to exploring the language use surrounding these interventions, and their implementation. Four databases were searched systematically...
December 1, 2023: Allergy
Soon Woo Hong, Kyung Hwa Chang, Chang Jae Woo, Ho Chul Kim, Bong Seop Kwak, Bong Joo Park, Ki Chang Nam
BACKGROUND: Nebulizers are commonly used to treat respiratory diseases, which are a major cause of morbidity and mortality. While inhalation therapy with antibodies has been evaluated in preclinical studies and clinical trials for respiratory diseases, it has not yet been approved for treatment. Moreover, there is limited information regarding the delivery efficiency of therapeutic antibodies via nebulizer. METHODS: In this study, the nebulization characteristics and drug delivery efficiencies were compared when immunoglobulin G (IgG) was delivered by five nebulizers using two airway models and five breathing patterns...
December 1, 2023: BMC Pharmacology & Toxicology
Bing Dai, Si Liu, Wenxin Shen, Li Chen, Qianlan Zhou, Lina Han, Qinzhen Zhang, Lishen Shan
BACKGROUND: Asthma is a heterogenous disease that characterized by airway remodeling. SYVN1 (Synoviolin 1) acts as an E3 ligase to mediate the suppression of endoplasmic reticulum (ER) stress through ubiquitination and degradation. However, the role of SYVN1 in the pathogenesis of asthma is unclear. RESULTS: In the present study, an ovalbumin (OVA)-induced murine model was used to evaluate the effect of SYVN1 on asthma. An increase in SYVN1 expression was observed in the lungs of mice after OVA induction...
December 2, 2023: Biological Research
Hyemin Hwang, Jae-Hyuk Jang, Eunyoung Lee, Hae-Sim Park, Jae Young Lee
BACKGROUND: Air pollution, weather, pollen, and influenza are typical aggravating factors for asthma. Previous studies have identified risk factors using regression-based and ensemble models. However, studies that consider complex relationships and interactions among these factors have yet to be conducted. Although deep learning algorithms can address this problem, further research on modeling and interpreting the results is warranted. METHODS: In this study, from 2015 to 2019, information about air pollutants, weather conditions, pollen, and influenza were utilized to predict the number of emergency room patients and outpatients with asthma using recurrent neural network, long short-term memory (LSTM), and gated recurrent unit models...
December 1, 2023: Respiratory Research
Driss Ousaaid, Meryem Bakour, Hassan Laaroussi, Asmae El Ghouizi, Badiaa Lyoussi, Ilham El Arabi
OBJECTIVES: Fruit vinegar is one of the most famous fruit byproducts worldwide with several unique properties. There are two types of fruit vinegar, artisanal and industrial, for consumers to choose from. This review aims to assess for the first time the phytochemistry of fruit vinegar and its anti-inflammatory effects. METHOD: The present work was conducted based on a literature search that selected the relevant papers from indexed databases such as Scopus, Science Direct, MDPI, PubMed, Hindawi, and Web of Science...
December 1, 2023: Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences
Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski
No abstract text is available yet for this article.
December 1, 2023: NPJ Primary Care Respiratory Medicine
Meng Ni, Baihe Li, Qianqian Zhang, Jiuru Zhao, Wei Li, Sudong Qi, Qianwen Shen, Dongting Yao, Ze Chen, Tao Wang, Xiya Ding, Zhenying Lin, Chunyu Cheng, Zhiwei Liu, Hao Chen
OBJECTIVE: To assess the association between birth weight and childhood asthma risk using data from the 2019-2020 National Survey of Children's Health database. DESIGN: Cross-sectional study. SETTING: The USA. PATIENTS: A representative cohort of American children. EXPOSURE: The exposure of this study was birth weight regardless of gestational age. Birth weight was divided into three groups: <1500 g, 1500-2500 g and >2500 g...
December 1, 2023: BMJ Open
Heidi Mikkola, Maarit Dimitrow, Katri Hämeen-Anttila, Emilia Laukkanen, Marja Airaksinen
OBJECTIVES: Disease self-management and medication therapy can cause burden to patients that can influence adherence. The conceptual model 'patients' lived experience with medicine' (PLEM) brings new insights into medication-related burden (MRB) from patient perspective. This study aimed to test the applicability of the PLEM model by interviewing chronically ill patients in Finland and to investigate the MRB experienced by the Finnish patients. DESIGN: Focus group discussion study conducted online via Zoom...
December 1, 2023: BMJ Open
N Ji, A Baptista, C H Yu, C Cepeda, F Green, M Greenberg, I Colon Mincey, P Ohman-Strickland, N Fiedler, H M Kipen, R J Laumbach
We examined associations between short-term exposure to traffic-related air pollutants (TRAP) and airway inflammation and lung function in children with asthma, and whether these associations are modified by chronic psychological stress. Residents of underresourced port-adjacent communities in New Jersey were concerned about the cumulative impacts of exposure to TRAP, particularly diesel-engine truck emissions, and stress on exacerbation of asthma among children. Children with asthma aged 9-14 (n = 35) were recruited from non-smoking households...
November 29, 2023: Science of the Total Environment
Ping He, Juan Hao, Ling-Fei Kong, Ayidana Wotan, Pan Yan, Yi-Cong Geng, Yi Wang, Zheng-Ying Li, Shi-Xian Hu, Bin Ren, Xiao-Juan Rong, Cai Tie
Resolvin (Rv) and lipoxin (Lx) play important regulative roles in the development of several inflammation-related diseases. The dysregulation of their metabolic network is believed to be closely related to the occurrence and development of asthma. The Hyssopus Cuspidatus Boriss extract (SXCF) has long been used as a treatment for asthma, while the mechanism of anti-inflammatory and anti-asthma action targeting Rv and Lx has not been thoroughly investigated. In this study, we aimed to investigate the effects of SXCF on Rv, Lx in ovalbumin (OVA)-sensitized asthmatic mice...
November 29, 2023: Prostaglandins & Other Lipid Mediators
Chengqian Zhang, Davide D'Angelo, Francesca Buttini, Mingshi Yang
Inhaled medicines continue to be an essential part of treatment for respiratory diseases such as asthma, chronic obstructive pulmonary disease, and cystic fibrosis. In addition, inhalation technology, which is an active area of research and innovation to deliver medications via the lung to the bloodstream, offers potential advantages such as rapid onset of action, enhanced bioavailability, and reduced side effects for local treatments. Certain inhaled macromolecules and particles can also end up in different organs via lymphatic transport from the respiratory epithelium...
November 29, 2023: Advanced Drug Delivery Reviews
Giselle S Mosnaim, Flavia C L Hoyte, Guilherme Safioti, Randall Brown, Tanisha Hill, Thomas Li, Katja Sagalovich, Michael DePietro, Michael E Wechsler
BACKGROUND: Digital health tools have been shown to help address challenges in asthma control, including inhaler technique, treatment adherence and short-acting beta2 -agonist overuse. The maintenance and reliever Digihaler System (DS) comprises two Digihaler inhalers (fluticasone propionate/salmeterol and albuterol) with an associated patient App and web-based Dashboard. Clinicians can review patients' inhaler use and Digihaler inhalation parameter data to support clinical decision-making...
November 29, 2023: Journal of Allergy and Clinical Immunology in Practice
Konstantinos Christopoulos
BACKGROUND: Exposure to birds has been linked with several lung pathologies and especially hypersensitivity pneumonitis, but discordant literature exist on the potential effects of this exposure on other respiratory pathologies. AIM: This study aims to examine the associations between bird ownership and asthma, lung cancer, and chronic obstructive pulmonary disease (COPD) in older European adults. METHODS: A total of 28,109 participants from the Survey of Health, Ageing, and Retirement in Europe were employed and analyzed with multivariate logistic regressions...
November 4, 2023: Respiratory medicine and research
Nájla Nonis Zucoloto, Felipe Silva de Aguiar, Natália Medeiros Dias Lopes, Ellen Cristine Duarte Garcia, Fabrizio Ricci Romano, Thiago Freire Pinto Bezerra, Wilma Terezinha Anselmo Lima, Marco Aurélio Fornazieri
OBJECTIVES: The aim of this observational cross-sectional study was to determine the endotypic inflammatory pattern of a sample of patients with CRS in Brazil, correlate it with olfactory function, and evaluate the clinical severity of the disease. METHODS: In this cross-sectional study, 73 CRS patients were recruited. Patients were classified into type 2 and non-type 2 endotypic patterns based on IgE and eosinophilia levels. All subjects performed the University of Pennsylvania Smell Identification Test (UPSIT®) and responded to the Sino-Nasal Outcome Test (SNOT-22)...
November 20, 2023: Brazilian Journal of Otorhinolaryngology
Jose Fernando Cantillo, Elizabeth Garcia, Enrique Fernandez-Caldas, Leonardo Puerta
Mosquito allergy has been conceived as the cutaneous reactions that appears during and after mosquito biting process; a perception that is supported by several scientific research. Additional data have led to conceive that other manifestations of allergic responses may occur as a cause of the exposure to somatic mosquito allergens. Two main phenotypes of mosquito allergy are identifiable: the cutaneous allergic reactions, induced by salivary allergens, and other manifestations of the allergic responses such as asthma and allergic rhino conjunctivitis that are caused by somatic allergens...
November 30, 2023: Molecular Immunology
Hiroyuki Nagase, Risako Ito, Moe Ishii, Hideki Shibata, Shintaro Suo, Isao Mukai, Shiyuan Zhang, Kieran J Rothnie, Claire Trennery, Liza Yuanita, Takeo Ishii
No abstract text is available yet for this article.
December 1, 2023: Advances in Therapy
L Stefano Ramirez-Gil, J J Ley-Tomas, J C Hernaiz-Leonardo, Isam Alobid, Joaquim Mullol, J C Ceballos-Cantu
PURPOSE OF REVIEW: To review the effects of endoscopic sinus surgery and endonasal approaches to the skull base on olfaction. RECENT FINDINGS: Advancements in endonasal endoscopic approaches to the sinuses and skull base allow for direct treatment of a variety of sinonasal and skull base diseases. However, these extended approaches will often require manipulation of normal anatomical structures and the olfactory neuroepithelium. Depending on the planned procedure and extent of disease, the prognosis of olfactory perception can vary significantly among patients...
December 1, 2023: Current Allergy and Asthma Reports
Yiwen Zhang, Ye Tingting, Wenzhong Huang, Pei Yu, Gongbo Chen, Rongbin Xu, Jiangning Song, Yuming Guo, Shanshan Li
PURPOSE OF REVIEW: Wildfire smoke is associated with human health, becoming an increasing public health concern. However, a comprehensive synthesis of the current evidence on the health impacts of ambient wildfire smoke on children and adolescents, an exceptionally vulnerable population, is lacking. We conduct a systematic review of peer-reviewed epidemiological studies on the association between wildfire smoke and health of children and adolescents. RECENT FINDINGS: We searched for studies available in MEDLINE, EMBASE, and Scopus from database inception up to October 11, 2022...
December 1, 2023: Current Environmental Health Reports
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