keyword
https://read.qxmd.com/read/38728563/repeat-radiosurgery-for-sporadic-vestibular-schwannoma-after-primary-radiosurgical-failure-an-international-multi-institutional-investigation
#21
MULTICENTER STUDY
Karl R Khandalavala, Hans A Herberg, Emily Kay-Rivest, Lindsay S Moore, Kristen L Yancey, John P Marinelli, Morten Lund-Johansen, Nikitha Kosaraju, Christine M Lohse, Walter Kutz, Peter L Santa Maria, John G Golfinos, Douglas Kondziolka, Matthew L Carlson, Øystein V Tveiten, Michael J Link
OBJECTIVE: To describe outcomes of patients with sporadic vestibular schwannoma (VS) who underwent repeat stereotactic radiosurgery (SRS) after primary SRS failure. STUDY DESIGN: Multi-institutional historical cohort study. SETTING: Five tertiary care referral centers. PATIENTS: Adults ≥18 years old with sporadic VS. INTERVENTION: Primary and repeat treatment with SRS. MAIN OUTCOME MEASURE: Microsurgery-free survival after repeat SRS...
June 1, 2024: Otology & Neurotology
https://read.qxmd.com/read/38726801/further-characterisation-of-late-somatosensory-evoked-potentials-using-electroencephalogram-and-magnetoencephalogram-source-imaging
#22
JOURNAL ARTICLE
Sahar Hssain-Khalladi, Alain Giron, Clément Huneau, Christophe Gitton, Denis Schwartz, Nathalie George, Michel Le Van Quyen, Guillaume Marrelec, Véronique Marchand-Pauvert
Beside the well-documented involvement of secondary somatosensory area, the cortical network underlying late somatosensory evoked potentials (P60/N60 and P100/N100) is still unknown. Electroencephalogram and magnetoencephalogram source imaging were performed to further investigate the origin of the brain cortical areas involved in late somatosensory evoked potentials, using sensory inputs of different strengths and by testing the correlation between cortical sources. Simultaneous high-density electroencephalograms and magnetoencephalograms were performed in 19 participants, and electrical stimulation was applied to the median nerve (wrist level) at intensity between 1...
May 10, 2024: European Journal of Neuroscience
https://read.qxmd.com/read/38726491/the-safety-of-volar-to-dorsal-percutaneous-screw-fixation-of-bennett-fracture-dislocation-a-cadaveric-study
#23
JOURNAL ARTICLE
Cheuk Bun Tse, Mark Zhu, Matthew Peter James Fisk, Joshua Andy Sevao
Background: Bennett fractures are traditionally fixed with percutaneous K-wires from dorsal to volar, or with a volar to dorsal screw via a volar open approach. While volar to dorsal screw fixation is biomechanically advantageous, an open approach requires extensive soft tissue dissection, thus increasing morbidity. This study aims to investigate the practicality and safety of Bennett fracture fixation using a percutaneous, volar to dorsal screw, particularly with regard to the median nerve and its motor branch during wire and screw insertion...
May 10, 2024: Journal of Hand Surgery Asian-Pacific Volume
https://read.qxmd.com/read/38723041/upper-extremity-nerve-transfers-for-treatment-of-nerve-injury-after-cervical-spine-surgery-a-single-center-retrospective-review
#24
JOURNAL ARTICLE
Véronique M Doucet, Tod A Clark, Jennifer L Giuffre
PURPOSE: Nerve transfers to restore or augment function after spinal cord injury is an expanding field. There is a paucity of information, however, on the use of nerve transfers for patients having undergone spine surgery. The incidence of neurologic deficit after spine surgery is rare but extremely debilitating. The purpose of this study was to describe the functional benefit after upper extremity nerve transfers in the setting of nerve injury after cervical spine surgery. METHODS: A single-center retrospective review of all patients who underwent nerve transfers after cervical spine surgery was completed...
May 9, 2024: Annals of Plastic Surgery
https://read.qxmd.com/read/38721949/stressful-life-events-psychiatric-comorbidities-and-serum-neuromediator-levels-in-patients-with-chronic-spontaneous-urticaria-treated-with-omalizumab
#25
JOURNAL ARTICLE
Akdaş Elçin, Gülekon Ayla, Bulut Tuba Saadet Deveci, Gülbahar Özlem, Öztürk Murat, Başaran Ahmet Selim, Coşar Behçet
INTRODUCTION: Many chronic spontaneous urticaria (CSU) patients have highly stressful life events and exhibit psychiatric comorbidities. Emotional stress can cause or exacerbate urticaria symptoms by causing mast cell degranulation via neuromediators. OBJECTIVES: To investigate the frequency of stressful life events and compare psychiatric comorbidities and serum neuromediator levels in patients with CSU who responded to omalizumab with healthy controls. METHODS: In this cross-sectional study, we included 42 patients with CSU who received at least 6 months of omalizumab treatment and a control group of 42 healthy controls...
2024: Allergologia et Immunopathologia
https://read.qxmd.com/read/38721514/neuroimaging-in-atypical-normal-tension-glaucoma-debating-routine-implementation-in-the-absence-of-classic-neurological-findings
#26
JOURNAL ARTICLE
Umay Güvenç, Gülizar Demirok, Güner Üney, Selma Uzman
AIM: To assess the necessity of neuroimaging in patients with neurological or atypical findings of normal tension glaucoma (NTG) who do not exhibit typical glaucoma manifestations. METHODS: A retrospective analysis was conducted on 90 atypical NTG patients who underwent cranial magnetic resonance imaging (MRI) due to atypical symptoms. The demographic characteristics, clinical parameters, and radiological findings were recorded. RESULTS: Among the patients, 66...
2024: International Journal of Ophthalmology
https://read.qxmd.com/read/38721468/pubourethral-and-uterosacral-male-analogues-suggest-parallel-male-female-pelvic-anatomy-and-symptom-pathogenesis
#27
REVIEW
Ahmed Farag, Sidi Muctar, Peter Petros
The thesis that functional/dysfunctional male/female pelvic floor anatomy are parallel, originated from two studies: a successful retropubic perineal male sling for post-prostatectomy stress urinary incontinence (SUI) and discovery of a male uterosacral ligament (USL) analogue, we named "prostatosacral ligament" (PSL). In 25 out of the studied 27 males (92.6%), it starts on both sides of the median sulcus of the prostate the ligament passes lateral to the rectum being fused with the lateral margin of the mesorectum before leaving it as it thins out to be attached posteriorly similar to the USL...
April 22, 2024: Annals of Translational Medicine
https://read.qxmd.com/read/38721442/comparative-evaluation-of-caudal-epidural-method-to-ultrasound-guided-s1-transforamen-block-in-patient-s-lumbar-discectomy-with-failed-back-syndrome-symptoms-a-double-blind-clinical-trial
#28
JOURNAL ARTICLE
Masoud Hashemi, Artadokht Khoshooei, Alireza Amanollahi, Sogol Asgari
BACKGROUND: Post-lumbar surgery syndrome (PLSS) refers to persistent or recurrent pain following spinal surgery with an unknown cause. It is commonly associated with epidural fibrosis (EF). Some studies suggest that epidural steroid injection (ESI) can effectively alleviate pain in PLSS, particularly when targeting the S1 nerve root using S1 transforaminal epidural steroid injection (S1-TFESI). A key factor in a successful block is accurately visualizing the first dorsal sacral foramen, and the needle's destination is the dorsal S1 foramen...
December 2023: Anesthesiology and Pain Medicine
https://read.qxmd.com/read/38715313/proximal-medial-gastrocnemius-recession-for-recalcitrant-plantar-fasciitis
#29
JOURNAL ARTICLE
Gaston A Slullitel, Pilar Martinez de Albornoz, Anna Oller Boix, Roberto Rey Cañas, Javier Vazquez Vidosa, Manuel Monteagudo de la Rosa
BACKGROUND: Recalcitrant plantar fasciitis (RPF) is characterized by its unresponsiveness to conservative treatments, and its surgical management remains controversial. Although there is some evidence to suggest that gastrocnemius recession can be an effective treatment for RPF, no large series of patients with mid- to long-term follow-up has been published. The objective of this study was to compare physical performance, as measured by the Foot and Ankle Ability Measure activities of daily living score (FAAM-ADL), and pain levels before and 1 year after undergoing proximal medial gastrocnemius recession (PMGR) as a treatment for RPF...
May 7, 2024: Foot & Ankle International
https://read.qxmd.com/read/38713595/fda-approval-summary-ciltacabtagene-autoleucel-for-relapsed-or-refractory-multiple-myeloma
#30
JOURNAL ARTICLE
Kavita Natrajan, Megha Kaushal, Bindu George, Bindu Kanapuru, Marc R Theoret
In February 2022, the U.S. Food and Drug Administration approved ciltacabtagene autoleucel, a chimeric antigen receptor (CAR) T cell therapy targeting the B-cell maturation antigen (BCMA), for adult patients with relapsed/refractory multiple myeloma (RRMM) after ≥4 lines of therapy including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 monoclonal antibody. Approval was based on overall response rate (ORR), complete response (CR) rate and duration of response (DOR) in 97 adult patients in a single-arm, open-label, multicenter phase 2 trial (CARTITUDE-1 [NCT03548207])...
May 7, 2024: Clinical Cancer Research
https://read.qxmd.com/read/38712918/children-with-hirschsprung-s-disease-have-high-morbidity-in-the-first-5%C3%A2-years-of-life
#31
JOURNAL ARTICLE
Mads Damkjær, Joachim Tan, Joan K Morris, Maria Loane, Joanne Given, Clara Cavero-Carbonell, Mika Gissler, Amanda J Neville, Anna Pierini, Anke Rissmann, David Tucker, Ester Garne
BACKGROUND: Hirschsprung's disease is a rare congenital anomaly of the colon with absence of the ganglionic nerve cells. The treatment of the anomaly is surgical. METHODS: This population-based data-linkage cohort study was part of the EUROlinkCAT project and investigated mortality and morbidity for the first 5 years of life for European children diagnosed with Hirschsprung's disease. Nine population-based registries in five countries from the European surveillance of congenital anomalies network (EUROCAT) participated...
May 2024: Birth Defects Research
https://read.qxmd.com/read/38711847/health-related-quality-of-life-in-patients-with-peripheral-nerve-tumors-results-from-the-german-multicentric-peripheral-nerve-tumor-registry
#32
JOURNAL ARTICLE
Nadja Grübel, Gregor Antoniadis, Uerschels Ak, Benjamin Mayer, Ralph König, Christian Rainer Wirtz, Andrej Pala, Nora F Dengler, Maria Teresa Pedro
OBJECTIVE: Peripheral nerve tumors (PNTs) are rare diseases. So far, no multicenter data on diagnostics, the efficacy of treatment, long-term outcomes, and health-related quality of life (HRQoL) exist. The establishment of the Peripheral Nerve Tumor Registry (PNTR) in 2015 allows for the systematic analysis of patients with tumors associated with peripheral nerves. The present study aims to investigate the impact of PNT on an individual's HRQoL and the effect of surgery. METHODS: HRQoL was pre- and postoperatively assessed by the Euro-Qol-5D-5L (EQ-5D-5L) and Euro-Qol visual analog scale (EQ-VAS) survey in the retrospective and prospective study arm in three active participating study centers...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38710168/effects-of-an-hour-computer-use-on-ulnar-and-median-nerve-conduction-velocity-and-muscle-activity-in-office-workers
#33
JOURNAL ARTICLE
Kanruethai Threesittidath, Supattra Chaibal, Haifah Nitayarak
OBJECTIVES: To compare the effects of the one-hour computer use on ulnar and median nerve conduction velocity and muscle activity in symptomatic neck pain and asymptomatic office workers. METHODS: A total of 40 participants, both male and female office workers, with symptomatic neck pain (n = 20) and asymptomatic (n = 20), were recruited. Pain intensity, ulnar nerve conduction velocity, median nerve conduction velocity, and muscle activity were conducted before and after one hour of computer use...
May 6, 2024: Journal of Occupational Health
https://read.qxmd.com/read/38709191/safety-and-effectiveness-of-brachial-artery-preclosure-by-purse-string-suture-technique-for-left-subclavian-artery-revascularization-in-stanford-b-aortic-dissection
#34
JOURNAL ARTICLE
Yiming Gu, Yadan Wang, Guoxiong Xu, Zhixuan Zhang, Chen Xu, Jingfan Yu, Changwen Fang
OBJECTIVES: To assess the safety and efficacy of the combination of brachial artery (BA) cutdown with purse-string suture (PSS) for BA preclosure during fenestrated thoracic endovascular aortic repair (f-TEVAR). METHODS: We reviewed the consecutive data in our center from January 2022 to May 2023. Clinical data were analyzed retrospectively, including the baseline characteristics, procedural details, complications, and outcomes. Dichotomous data were summarized as absolute values and percentages...
May 6, 2024: Vascular and Endovascular Surgery
https://read.qxmd.com/read/38708872/ultra-high-frequency-ultrasound-of-fascicles-in-the-ulnar-and-radial-nerves
#35
JOURNAL ARTICLE
James B Meiling, Rachana K Gandhi Mehta, Vanessa Baute Penry, Michael S Cartwright, Marisa Barclay McGhee
INTRODUCTION/AIMS: Ultra high-frequency ultrasound (UHFUS) has been demonstrated to allow easy visualization and quantification of median and digital nerve fascicles; however, there is a lack of normative data for other upper limb nerves. The purpose of this study was to use UHFUS to establish normative reference values and ranges for fascicle count and density within selected upper extremity nerves. METHODS: Twenty-one healthy volunteers underwent sonographic examination of the ulnar, superficial branch of the radial, and radial nerves on one upper limb using UHFUS with a 48 MHz linear transducer...
May 6, 2024: Muscle & Nerve
https://read.qxmd.com/read/38707768/peripapillary-retinal-nerve-fiber-layer-thickness-as-a-predictor-of-visual-outcomes-in-patients-with-acute-nonarteritic-anterior-ischemic-optic-neuropathy
#36
JOURNAL ARTICLE
Sivapoj Sriwannavit, Tanyatuth Padungkiatsagul, Panitha Jindahra, Kavin Vanikieti
OBJECTIVE: To evaluate the utility of peripapillary retinal nerve fiber layer thickness (pRNFLT) for the prediction of visual outcomes, including visual acuity (VA) and visual field (VF), in subjects with acute nonarteritic anterior ischemic optic neuropathy (NAION). MATERIALS AND METHODS: We performed a retrospective study of data relating to 60 eyes of 60 subjects with acute NAION. Of these, reliable VF values were obtained at both the initial and at 6-month follow-up visits for 30 eyes, which were included in the VF analysis...
2024: Clinical Ophthalmology
https://read.qxmd.com/read/38707561/treating-pathological-metastatic-fractures-of-the-humerus-by-compound-osteosynthesis-a-retrospective-cohort-study
#37
JOURNAL ARTICLE
Valérie Fischer, Vilijam Zdravkovic, Matthijs Jacxsens, Andreas Toepfer, Bernhard Jost
BACKGROUND: The number of malignant tumors is increasing as are bone metastases, such as those in the humerus. Arm function is important for an independent everyday life. In this study, compound osteosynthesis of metastatic fractures of the humerus is examined for its suitability in light of the competing risk of death. METHODS: This retrospective monocentric study includes a cohort of tumor patients who underwent primary compound osteosynthesis for pathological humeral fractures...
May 2024: JSES international
https://read.qxmd.com/read/38707043/unilateral-pushup-induced-acute-median-neuritis
#38
Alexis M Ruppel, Mitchell J Lomis, Scarlett E Schneider
Acute median nerve neuropathy is most often due to trauma; acute carpal tunnel syndrome is considered a surgical emergency and must be ruled out. A right-hand dominant male presented to the emergency department with progressive unilateral pain and numbness in the median nerve distribution after experiencing a pop while doing pushups. The evaluation was limited to pain, but there was no gross deformity, and the distal right upper extremity was neurovascularly intact. All imaging was unremarkable. The patient received adequate pain control and complete resolution of symptoms...
April 2024: Curēus
https://read.qxmd.com/read/38706790/the-role-of-surgery-to-relieve-symptomatic-cutaneous-t-cell-lymphoma-refractory-to-medical-treatments
#39
Wesley Q Zhang, Emily E Hecox, Shireen Dogar, Marc E Walker
Background: Though mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL), it has no curative treatment. The aim of current topical and systemic treatment is centered around relieving symptoms and optimizing disease-free time. The use of surgical management to achieve the same goals of symptomatic reduction is not well described in the current literature. Methods: We present a case of refractory MF that failed chemotherapy, radiotherapy, and UV light therapy. Despite medical management, the tumor burden progressed to significant compression neuropathy of the ulnar and median nerves...
2024: Case Reports in Oncological Medicine
https://read.qxmd.com/read/38706371/correlation-and-influencing-factors-of-neurophysiological-examinations-and-serum-uric-acid-in-patients-with-diabetic-peripheral-neuropathy-an-exploratory-study
#40
JOURNAL ARTICLE
Huimin Wang, Jia Jia
Objective: This study aimed to investigate the correlation and influencing factors between neurophysiological examinations, serum uric acid (SUA), and glucose metabolism in patients with Diabetic Peripheral Neuropathy (DPN). Methods: A total of 114 patients with DPN who received treatment at the Endocrinology Department of our hospital from January 2022 to December 2023 were included. According to the median blood uric acid level, the patients were divided into high SUA group and low SUA group, and the demographic data, blood glucose indexes and sensory nerve electrophysiological examination results of the two groups were compared...
May 6, 2024: International Journal of Neuroscience
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