Francesca Bosco, Vincenzo Musolino, Micaela Gliozzi, Saverio Nucera, Cristina Carresi, Maria Caterina Zito, Federica Scarano, Miriam Scicchitano, Fabio Reale, Stefano Ruga, Jessica Maiuolo, Roberta Macrì, Lorenza Guarnieri, Anna Rita Coppoletta, Rocco Mollace, Carolina Muscoli, Ernesto Palma, Vincenzo Mollace
Skeletal muscles and bone tissue form the musculoskeletal apparatus, a complex system essential for the voluntary movement. The loss of muscle mass and muscle strength is often associated with a loss of bone mass, in a "hazardous duet" which implies the co-existence of sarcopenia-osteoporosis and exposes patients to a deterioration in quality of life and increased mortality. From the mechanostat theory to the recent definition of the osteosarcopenia syndrome, many aspects of muscle-bone interaction have been investigated in recent decades...
January 13, 2021: Pharmacological Research: the Official Journal of the Italian Pharmacological Society