David Sweet , Julian Marsden , Kendall Ho , Christina Krause , James A Russell
Many emergency departments have implemented sepsis protocols since the 2001 publication of results from the early goal-directed therapy trial, which showed early targeted resuscitation lowers mortality. As part of an attempt to improve clinical and operational outcomes for emergency departments across British Columbia, we reviewed sepsis management literature and considered sepsis protocol implementation in the province’s emergency departments. During the literature review we found that many observational studies confirmed an association between implementation of emergency sepsis protocols and decreased mortality...
May 2012: British Columbia Medical Journal
Lauren E Powell, William J Brady, Robert C Reiser, Daniel J Beckett
No abstract text is available yet for this article.
January 8, 2021: American Journal of Emergency Medicine
Kendall A Ulbrich, Katelyn Zumpf, Jody D Ciolino, Malika Shah, Emily S Miller, Katherine L Wisner
OBJECTIVE: To determine whether full-term neonates with in utero exposure to selective serotonin reuptake inhibitors (SSRI) require respiratory support in the delivery room, as indicated by the standardized Neonatal Resuscitation Program [NRP] algorithm, significantly more often than non-exposed neonates. STUDY DESIGN: In this retrospective cohort study, we extracted data from medical records of full-term neonates with and without in utero SSRI exposure, defined as documentation of third trimester maternal SSRI treatment...
January 13, 2021: Journal of Pediatrics
Thierry Pelaccia, Jean Sibilia, Élodie Fels, Lucas Gauer, Audrey Musanda, François Severac, Milena Abbiati
The COVID-19 pandemic has led to increased staffing needs in emergency departments. The question quickly arose as to whether it was appropriate to offer medical students the opportunity to assist this staff. The dilemma stems in part from the potential impact on their psychological well-being as well as their academic and clinical performances. We sought to determine the level of anxiety of medical students during the COVID-19 outbreak, and whether it was higher among the students who chose to return to the clinical setting, especially in first-line units (i...
January 16, 2021: Internal and Emergency Medicine
Ashok Kumar, Ravi Prakash Yadav, Sriparna Basu, T B Singh
OBJECTIVE: To compare the effect of suctioning first or drying first on the composite outcome of hypothermia or respiratory distress in depressed newborns requiring delivery room resuscitation. DESIGN: Open-label, randomized, parallel-group, controlled trial. SETTING: Delivery room and neonatal intensive care unit of a tertiary-care teaching hospital. PATIENTS: Depressed newborns (n=154) requiring initial steps of resuscitation at birth...
January 15, 2021: Indian Pediatrics
Ravi Taneja, Robert Sibbald, Launa Elliott, Elizabeth Burke, Kristen A Bishop, Philip M Jones, Mark Goldszmidt
PURPOSE: A discordance, predominantly towards overtreatment, exists between patients' expressed preferences for life-sustaining interventions and those documented at hospital admission. This quality improvement study sought to assess this discordance at our institution. Secondary objectives were to explore if internal medicine (IM) teams could identify patients who might benefit from further conversations and if the discordance can be reconciled in real-time. METHODS: Two registered nurses were incorporated into IM teams at a tertiary hospital to conduct resuscitation preference conversations with inpatients either specifically referred to them (group I, n = 165) or randomly selected (group II, n = 164) from 1 August 2016 to 31 August 2018...
January 15, 2021: Canadian Journal of Anaesthesia
Norihiro Nishioka, Daisuke Kobayashi, Junichi Izawa, Taro Irisawa, Tomoki Yamada, Kazuhisa Yoshiya, Changhwi Park, Tetsuro Nishimura, Takuya Ishibe, Yoshiki Yagi, Takeyuki Kiguchi, Masafumi Kishimoto, Toshiya Inoue, Yasuyuki Hayashi, Taku Sogabe, Takaya Morooka, Haruko Sakamoto, Keitaro Suzuki, Fumiko Nakamura, Tasuku Matsuyama, Yohei Okada, Satoshi Matsui, Atsushi Hirayama, Satoshi Yoshimura, Shunsuke Kimata, Takeshi Shimazu, Tetsuhisa Kitamura, Takashi Kawamura, Taku Iwami
We aimed to investigate the association between serum lactate levels during cardiopulmonary resuscitation (CPR) and survival in patients with out-of-hospital cardiac arrest (OHCA). From the database of a multicenter registry on OHCA patients, we included adult nontraumatic OHCA patients transported to the hospital with ongoing CPR. Based on the serum lactate levels during CPR, the patients were divided into four quartiles: Q1 (≤ 10.6 mEq/L), Q2 (10.6-14.1 mEq/L), Q3 (14.1-18.0 mEq/L), and Q4 (> 18...
January 15, 2021: Scientific Reports
Jiesi Lei, Xue Guo, Yufei Zeng, Jizhong Zhou, Qun Gao, Yunfeng Yang
As the second-largest terrestrial carbon (C) flux, soil respiration (RS ) has been stimulated by climate warming. However, the magnitude and dynamics of such stimulations of soil respiration are highly uncertain at the global scale, undermining our confidence in future climate projections. Here, we present an analysis of global RS observations from 1987-2016. RS increased (P < 0.001) at a rate of 27.66 g C m-2  yr-2 (equivalent to 0.161 Pg C yr-2 ) in 1987-1999 globally but became unchanged in 2000-2016, which were related to complex temporal variations of temperature anomalies and soil C stocks...
January 15, 2021: Nature Communications
Ioannis Bellos, Georgia Fitrou, Raffaella Panza, Aakash Pandita
OBJECTIVES: To compare surfactant administration via thin catheters, laryngeal mask, nebulisation, pharyngeal instillation, intubation and surfactant administration followed by immediate extubation (InSurE) and no surfactant administration. DESIGN: Network meta-analysis. SETTING: Medline, Scopus, CENTRAL, Web of Science, Google-scholar and databases were systematically searched from inception to 15 February 2020. PATIENTS: Preterm neonates with respiratory distress syndrome...
January 15, 2021: Archives of Disease in Childhood. Fetal and Neonatal Edition
Madeleine C Murphy, Allan Jenkinson, John Coveney, Lisa K McCarthy, Colm Patrick Finbarr O Donnell
AIM: To determine whether the IntelliVue monitor (ECG plus Masimo pulse oximeter (PO)) displays heart rate (HR) at birth more quickly than Nellcor PO (PO alone) among infants of 29-35 weeks' gestational age. METHODS: Unmasked parallel group randomised (1:1) study. RESULTS: We planned to enrol 100 infants; however, the study was terminated due to the COVID-19 pandemic when 39 infants had been enrolled (17 randomised to IntelliVue, 22 to Nellcor)...
January 15, 2021: Archives of Disease in Childhood. Fetal and Neonatal Edition
Shaista Meghani
BACKGROUND: The advance in the practice of resuscitation is globally recognised and fully sanctioned in scientific world. However, practicing family presence during resuscitation, also known as witnessed resuscitation, is yet to be endorsed by healthcare professionals. Many professional nursing and physician organisations have endorsed the practice of witnessed resuscitation by issuing guidelines. These organisations support family presence during resuscitation due to the research proving its benefit for patients and families...
January 12, 2021: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
Maureen L Douglas, Jessica Simon, Sara N Davison, Patricia Biondo, Sunita Ghosh, Aliya Kassam, Konrad Fassbender
BACKGROUND: Patient videos about advance care planning (ACP; hereafter "Videos"), were developed to support uptake of provincial policy and address the complexity of patients' decision-making process. We evaluate self-administered ACP Videos, compare the studies' choice of outcomes, show correlations between the patients' ACP actions, and discuss implications for health care policy. OBJECTIVE: To test the efficacy of the Videos on patients' ACP/goals of care designation conversations with a health care provider...
January 15, 2021: Medical Decision Making: An International Journal of the Society for Medical Decision Making
Birte Weber, Ina Lackner, Florian Gebhard, Theodore Miclau, Miriam Kalbitz
Trauma remains a leading global cause of mortality, particularly in the young population. In the United States, approximately 30,000 patients with blunt cardiac trauma were recorded annually. Cardiac damage is a predictor for poor outcome after multiple trauma, with a poor prognosis and prolonged in-hospitalization. Systemic elevation of cardiac troponins was correlated with survival, injury severity score, and catecholamine consumption of patients after multiple trauma. The clinical features of the so-called "commotio cordis" are dysrhythmias, including ventricular fibrillation and sudden cardiac arrest as well as wall motion disorders...
January 13, 2021: International Journal of Molecular Sciences
Tirsa M Ferrer Marrero, Mark Barash, Besma Jaber, Meghan Nothem, Kumar Shah, Matthew W Weber, Stephanie Zellner Jones, Patrick Kennedy, Jeanette Graf, Shannon Broaddrick, Zhuping Garacci, Anjishnu Banerjee, Jennifer Kryworuchko, Jayshil Patel
PURPOSE: To test the primary hypothesis that a CPR video will reduce ICU patients' surrogates' anxiety when deciding code status, as measured by the Hamilton Anxiety Rating (HAM-A) Scale, as compared to the no video group. MATERIALS AND METHODS: This is a prospective randomized control trial. Twenty-seven ICU patients' surrogates were enrolled in the study after receiving an ICU team-led code status discussion. After the enrollment, twelve surrogates were randomized to the video group and fifteen to the no video group...
December 3, 2020: Journal of Critical Care
Kenneth E Mah, Jeffrey A Alten, Timothy T Cornell, David T Selewski, David Askenazi, Julie C Fitzgerald, Alexis Topjian, Kent Page, Richard Holubkov, Beth S Slomine, James R Christensen, J Michael Dean, Frank W Moler
AIM: Determine 1) frequency and risk factors for acute kidney injury (AKI) after in-hospital cardiac arrest (IHCA) in the Therapeutic Hypothermia after Pediatric Cardiac Arrest In-Hospital (THAPCA-IH) trial and associated outcomes; 2) impact of temperature management on post-IHCA AKI. METHODS: Secondary analysis of THAPCA-IH; a randomized controlled multi-national trial at 37 children's hospitals. ELIGIBILITY: Serum creatinine (Cr) within 24 h of randomization...
January 12, 2021: Resuscitation
Lisa M Vallely, Rachel Smith, Moses Laman, Michaela A Riddell, Alice Mengi, Lucy Au, Cherolyn Polomon, Joshua P Vogel, William S Pomat, Andrew J Vallely, Caroline Se Homer
AIM: To determine the causes of early neonatal death and the avoidable factors associated with these deaths among women participating in a cluster-randomised crossover trial in Papua New Guinea. METHODS: Early neonatal deaths were identified by retrospective chart review of the Women and Newborn Trial of Antenatal Interventions and Management study participants between July 2017 and January 2020. Causes of death and avoidable factors were identified using the Perinatal Problem Identification Program system...
January 15, 2021: Journal of Paediatrics and Child Health
Yuancheng Li, Xiuming Liu, Fuyao Yang, Jie Wang, Yuanwei Xu, TingTing Fang, LuTong Pu, XiaoYue Zhou, Yuchi Han, Yucheng Chen
OBJECTIVE: To investigate the prognostic significance of T1 mapping using T1 long and short in hypertrophic cardiomyopathy (HCM) patients. METHODS: A total of 263 consecutive patients with HCM referred for cardiovascular magnetic resonance (CMR) imaging were enrolled in this study. The imaging protocol consisted of cine, late gadolinium enhancement (LGE), and T1 mapping with T1 long and short. All patients were followed up prospectively. Outcome events were divided into the primary and secondary endpoint events...
January 15, 2021: European Radiology
Thomas K Wood, Sooyeon Song
Procaryotes starve and face myriad stresses. The bulk population actively resists the stress, but a small population weathers the stress by entering a resting stage known as persistence. No mutations occur, and so persisters behave like wild-type cells upon removal of the stress and regrowth; hence, persisters are phenotypic variants. In contrast, resistant bacteria have mutations that allow cells to grow in the presence of antibiotics, and tolerant cells survive antibiotics better than actively-growing cells due to their slow growth (such as that of the stationary phase)...
December 2020: Biofilm
Markus Bettin, Matthias Koopmann, Gerold Mönnig, Christian Pott
Background: Accelerated idioventricular rhythm (AIVR) is known as reperfusion arrhythmia in the setting of acute myocardial infarction (AMI). In healthy individuals, it is usually considered to be benign. Alternating bundle branch block (ABBB) often progresses to complete atrioventricular block requiring permanent pacemaker implantation. We report a case of delayed appearance of AIVR following myocardial infarction (MI) in combination with ABBB as precursor of sudden cardiac arrest due to ventricular fibrillation (VF)...
December 2020: European Heart Journal. Case Reports
Matthias Ebner, Niklas Guddat, Karsten Keller, Marie Christine Merten, Markus H Lerchbaumer, Gerd Hasenfuß, Stavros V Konstantinides, Mareike Lankeit
While numerous studies have confirmed the prognostic role of high-sensitivity troponin T (hsTnT) in pulmonary embolism (PE), high-sensitivity troponin I (hsTnI) is inappropriately studied. This study aimed to investigate the prognostic relevance of hsTnI in normotensive PE, establish the optimal cut-off value for risk stratification and to compare the prognostic performances of hsTnI and hsTnT. Based on data from 459 consecutive PE patients enrolled in a single-centre registry, receiver operating characteristic analysis was used to identify an optimal hsTnI cut-off value for prediction of in-hospital adverse outcomes (PE-related death, cardiopulmonary resuscitation or vasopressor treatment) and all-cause mortality...
October 2020: ERJ Open Research
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"