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JOURNAL ARTICLE
Chao Zhang, Jonathan Salamon, Ren Zhang
Cardiovascular disease is a major threat to global public health. Tissue plasminogen activator (TPA) is a serine protease that dissolves blood clots, which can also lead to excessive bleeding. Fibrinogen (FIBR), a glycoprotein, is converted by thrombin to fibrin and then to a fibrin-based blood clot. Both TPA and FIBR levels in the blood are associated with an increased risk of coronary heart disease, and the levels of the two factors are also positively correlated with total adipose tissue amounts. Visceral and subcutaneous adipose tissues (VAT and SAT) can contribute differently to whole-body metabolism...
December 4, 2022: Nutrients
#62
JOURNAL ARTICLE
Daniel Caldeira, Beatriz Nogueira-Garcia, Ana Abreu, Fausto J Pinto
BACKGROUND: Dietary habits with fish consumption have been associated with a lower risk of cardiovascular (CV) disease, based on heterogenous observational studies. Current recommendations suggest eating at least 1-2 fish servings per week for CV prevention. METHODS: We conducted a retrospective evaluation of a cohort study that enrolled a large primary prevention population to determine the potential benefit of fish intake ≥1.5 serving per week, through a multivariate Cox regression model...
December 8, 2022: European Journal of Clinical Nutrition
#63
JOURNAL ARTICLE
Xue Cao, Zhenping Zhao, Yuting Kang, Yixin Tian, Yuxin Song, Limin Wang, Linfeng Zhang, Xin Wang, Zuo Chen, Congyi Zheng, Lu Tian, Peng Yin, Yuehui Fang, Mei Zhang, Yuna He, Zugui Zhang, William S Weintraub, Maigeng Zhou, Zengwu Wang
BACKGROUND: Temporal trends and geographical variations in cardiovascular disease attributable to high systolic blood pressure in China are not yet fully understood. The aim of this study was to quantify the cardiovascular disease burden attributable to high systolic blood pressure at national and provincial levels in China. METHODS: In this population-based study, we evaluated systolic blood pressure and estimated the number of deaths, age-standardised mortality rates, and years of life lost (YLLs) due to cardiovascular disease and its subcategories (including ischaemic heart disease, ischaemic stroke, haemorrhagic stroke, and other cardiovascular diseases) attributable to high systolic blood pressure, at the national level and by 31 provincial levels, in China, from 2005 to 2018...
December 2022: Lancet. Public Health
#64
REVIEW
Kit-Leong Cheong, Biao Yu, Jing Chen, Saiyi Zhong
Cardiovascular disease (CVD) is the number one cause of death worldwide. Recent evidence has demonstrated an association between the gut microbiota and CVD, including heart failure, cerebrovascular illness, hypertension, and stroke. Marine algal polysaccharides (MAPs) are valuable natural sources of diverse bioactive compounds. MAPs have many pharmaceutical activities, including antioxidant, anti-inflammatory, immunomodulatory, and antidiabetic effects. Most MAPs are not utilized in the upper gastrointestinal tract; however, they are fermented by intestinal flora...
November 8, 2022: Foods (Basel, Switzerland)
#65
JOURNAL ARTICLE
Lauren Jane Klein, Shehu Abdullahi, Safiya Gambo, Virginia A Stallings, Sari Acra, Mark Rodeghier, Michael R DeBaun
Undernutrition is a risk factor for under 5 mortality and is also postulated to be a risk factor for mortality in older children and adults with sickle cell anemia. We tested the hypothesis that underweight (weight-for-age z-score <-1) is associated with mortality in children aged 5-12 years with sickle cell anemia. We performed a secondary analysis of participants in the Primary Prevention of Stroke in Children with Sickle Cell Disease in Nigeria trial, a double-blind, parallel-group randomized controlled trial for low-dose (n=109) or moderate-dose (n=111) hydroxyurea in children with abnormal transcranial Doppler velocities and a comparison group (n=211) of participants with non-elevated transcranial Doppler velocities in northern Nigeria (NCT02560935)...
November 16, 2022: Blood Advances
#66
JOURNAL ARTICLE
Liam Gaziano, Luanluan Sun, Matthew Arnold, Steven Bell, Kelly Cho, Stephen K Kaptoge, Rebecca J Song, Stephen Burgess, Daniel C Posner, Katja Mosconi, Cassianne Robinson-Cohen, Amy M Mason, Thomas R Bolton, Ran Tao, Elias Allara, Petra Schubert, Lingyan Chen, James R Staley, Natalie Staplin, Servet Altay, Pilar Amiano, Volker Arndt, Johan Ärnlöv, Elizabeth L M Barr, Cecilia Björkelund, Jolanda M A Boer, Hermann Brenner, Edoardo Casiglia, Paolo Chiodini, Jackie A Cooper, Josef Coresh, Mary Cushman, Rachel Dankner, Karina W Davidson, Renate T de Jongh, Chiara Donfrancesco, Gunnar Engström, Heinz Freisling, Agustín Gómez de la Cámara, Vilmundur Gudnason, Graeme J Hankey, Per-Olof Hansson, Alicia K Heath, Ewout J Hoorn, Hironori Imano, Simerjot K Jassal, Rudolf Kaaks, Verena Katzke, Jussi Kauhanen, Stefan Kiechl, Wolfgang Koenig, Richard A Kronmal, Cecilie Kyrø, Deborah A Lawlor, Börje Ljungberg, Conor MacDonald, Giovanna Masala, Christa Meisinger, Olle Melander, Conchi Moreno Iribas, Toshiharu Ninomiya, Dorothea Nitsch, Børge G Nordestgaard, Charlotte Onland-Moret, Luigi Palmieri, Dafina Petrova, Jose Ramón Quirós Garcia, Annika Rosengren, Carlotta Sacerdote, Masaru Sakurai, Carmen Santiuste, Matthias B Schulze, Sabina Sieri, Johan Sundström, Valérie Tikhonoff, Anne Tjønneland, Tammy Tong, Rosario Tumino, Ioanna Tzoulaki, Yvonne T van der Schouw, W M Monique Verschuren, Henry Völzke, Robert B Wallace, S Goya Wannamethee, Elisabete Weiderpass, Peter Willeit, Mark Woodward, Kazumasa Yamagishi, Raul Zamora-Ros, Elvis A Akwo, Saiju Pyarajan, David R Gagnon, Philip S Tsao, Sumitra Muralidhar, Todd L Edwards, Scott M Damrauer, Jacob Joseph, Lisa Pennells, Peter W F Wilson, Seamus Harrison, Thomas A Gaziano, Michael Inouye, Colin Baigent, Juan P Casas, Claudia Langenberg, Nick Wareham, Elio Riboli, J Michael Gaziano, John Danesh, Adriana M Hung, Adam S Butterworth, Angela M Wood, Emanuele Di Angelantonio
BACKGROUND: End-stage renal disease is associated with a high risk of cardiovascular events. It is unknown, however, whether mild-to-moderate kidney dysfunction is causally related to coronary heart disease (CHD) and stroke. METHODS: Observational analyses were conducted using individual-level data from 4 population data sources (Emerging Risk Factors Collaboration, EPIC-CVD [European Prospective Investigation into Cancer and Nutrition-Cardiovascular Disease Study], Million Veteran Program, and UK Biobank), comprising 648 135 participants with no history of cardiovascular disease or diabetes at baseline, yielding 42 858 and 15 693 incident CHD and stroke events, respectively, during 6...
November 15, 2022: Circulation
#67
JOURNAL ARTICLE
Alex Buoite Stella, Paolo Manganotti
BACKGROUND: Enteral nutrition is often prescribed in acute stroke to meet energy and fluid needs in patients with dysphagia. Tubes clogging represent a common complication of enteral formula delivery, requiring substitution and influencing nutrition administration. Frequent water flushes are recommended as one of the most effective procedures to prevent tube occlusion, but it might be time demanding and not consistently performed by the healthcare staff. This study aimed to assess the efficacy of an automatic flush pump, compared to a manual flush system, to prevent tubes' occlusions in acute-stroke patients, as this might affect nutrition and hydration...
October 20, 2022: Sensors
#68
JOURNAL ARTICLE
Jin G Choi, Aaron N Winn, M Reza Skandari, Melissa I Franco, Erin M Staab, Jason Alexander, Wen Wan, Mengqi Zhu, Elbert S Huang, Louis Philipson, Neda Laiteerapong
BACKGROUND: Guidelines recommend sodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP1) receptor agonists as second-line therapy for patients with type 2 diabetes. Expanding their use as first-line therapy has been proposed but the clinical benefits may not outweigh their costs. OBJECTIVE: To evaluate the lifetime cost-effectiveness of a strategy of first-line SGLT2 inhibitors or GLP1 receptor agonists. DESIGN: Individual-level Monte Carlo-based Markov model...
October 2022: Annals of Internal Medicine
#69
JOURNAL ARTICLE
Kaijing Wang, Liyou Lian, Chengpu Chen, Meiling Wang, Chen Chen, Xiang Hu
Background: The aim of our study was to evaluate changes in nutritional status as measured by the prognostic nutritional index (PNI) and geriatric nutritional risk index (GNRI) scores, and their abilities to predict clinical prognosis in patients with pacemaker implantation (PMI). Methods: A total of 595 patients who underwent permanent PMI from January 2011 to December 2020 were included. PNI and GNRI scores were separately calculated at the beginning day of PMI operation and at the end of 12-month follow-up, and their net changes (Δ) were calculated by PNI or GNRI scores at follow-up minus the corresponding scores on admission...
2022: Frontiers in Nutrition
#70
JOURNAL ARTICLE
Xiu Hong Yang, Bao Long Zhang, Yun Cheng, Shun Kun Fu, Hui Min Jin
AIMS: Considering the lack of evidence on statin use and the risk of cardiovascular disease (CVD) in patients with diabetes in primary and secondary prevention, this study aimed to evaluate the effect of statin use in individuals with diabetes for primary and secondary prevention. DATA SYNTHESIS: The MEDLINE, Web of Science, Embase, ClinicalTrials.gov, and Cochrane Central Register for Controlled Trials databases were searched. We included studies that assessed the effect of statin use in individuals with diabetes for at least 1 year...
August 8, 2022: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
#71
REVIEW
Jaineet Singh Chhabra, Amandeep Juneja, Yana Etkin, Gregg Landis, Hannah Gardener, Melissa Garuthara, Tabea Hoffstaetter, Alisha Oropallo
Background: An estimated 33% reduction in cardiovascular events can be achieved when incorporating whole grains, fruits, vegetables, poultry, nuts, and vegetable oils in the diet along with reduced consumption of refined carbohydrates, processed meats, and sugar sweetened beverages. We performed a systematic review to analyze the impact of nutritional intervention on stroke risk, as there is no current consensus concerning dietary recommendation for primary and secondary stroke prevention. Methods: A literature search of the PubMed database from January 2010 to June 2020 was performed using combinations of the following search terms: carotid disease, carotid artery disease, carotid stenosis, carotid intima-media thickness (CIMT), diet, nutrition, micronutrition, embolic stroke, and stroke...
June 2023: Nutrition and Health
#72
JOURNAL ARTICLE
Kae-Woei Liang, Chia-Lin Lee, Wei-Ju Liu
Consuming a Mediterranean-style diet (MED) is helpful for primary prevention of atherosclerotic cardiovascular disease (ASCVD). However, few studies have compared mortality in ASCVD subjects with different degrees of adherence to the MED diet or have evaluated the contributions of individual diet components. We analyzed National Health and Nutrition Examination Survey (NHANES) participants with a history of coronary heart disease (CHD) or stroke (N = 2052) in a period from 1999 to 2010. Their individual vital status was linked to the National Death Index till the end of 2011...
August 5, 2022: Nutrients
#73
JOURNAL ARTICLE
Qian Xu, Lingling Du, Heng Gu, Meng Ji, Ling Zhan
BACKGROUND: in recent years, n-3 PUFAs have been confirmed to be associated with cardiovascular and cerebrovascular diseases, but the link between n-3 PUFAs and stroke remains controversial. OBJECTIVE: this study aimed to evaluate the association between n-3 PUFAs and stroke. METHODS: we performed a comprehensive search of the following electronic databases: PubMed, Embase, Cochrane Library, Web of Science and CNKI. Literature screening and quality assessment were performed according to inclusion and exclusion criteria...
August 2, 2022: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
#74
JOURNAL ARTICLE
Karima Benameur, Nikhila Gandrakota, Mohammed K Ali
BACKGROUND: Poor diet quality has been found to be an independent risk factor for mortality in stroke. However, it is unknown to what extent Neurologists are trained and are comfortable enough to provide dietary counseling to stroke patients. OBJECTIVE: To assess the knowledge, attitudes, and practices of neurology residents relating to dietary counseling of stroke patients. METHODS: An online anonymous survey was administered to neurology residents throughout the country between August and November 2019 among a total of 109 (68%) US neurology programs...
2022: Frontiers in Neurology
#75
JOURNAL ARTICLE
Hong Jiang, Lina Wang, Duolao Wang, Ni Yan, Chao Li, Min Wu, Fan Wang, Baibing Mi, Fangyao Chen, Wanru Jia, Xi Liu, Jiaxin Lv, Yan Liu, Jing Lin, Le Ma
BACKGROUND & AIMS: Considerable attention has focused on the role of omega-3 polyunsaturated fatty acids (PUFA) in the prevention of cardiometabolic diseases, which has led to dietary recommendations to increase omega-3 fatty acid intake. A meta-analysis was conducted to summarize evidence from prospective studies regarding associations between omega-3 PUFA biomarkers and risk of developing major chronic diseases. METHODS: Four electronic databases were searched for articles from inception to March 1, 2022...
August 2022: Clinical Nutrition
#76
JOURNAL ARTICLE
Richard Paisey, Charles Daniels, Will Howitt, Derek Greatorex, Claire Campbell, Christopher Paisey, Rosamund Paisey, Julie Frost, Robert Bromige
Objective: To assess weight loss maintenance, diabetes status, mortality and morbidity 15 years after a very low calorie diet programme (VLCD) in patients with obesity. Design: General practice data bases were interrogated for subjects coded for group therapy with VLCD in the 1990s. Causes of death, occurrence of vascular disease and remission or development of diabetes were ascertained from patient records and national stroke and cardiovascular disease data bases...
2022: BMJ nutrition, prevention & health
#77
REVIEW
Klaudia Marek, Natalia Cichoń, Joanna Saluk-Bijak, Michał Bijak, Elżbieta Miller
Hypovitaminosis D is a serious public health problem, representing an independent factor in mortality among the general population. Vitamin D deficiency may affect up to one billion people worldwide. Recently, the potential association between vitamin D levels and stroke has gained increasing attention. Many studies suggest that maintaining normal serum vitamin D levels is associated with improvement of the cardiovascular system and a reduction in stroke risk. As a neurosteroid, vitamin D influences brain development and function and immunomodulation and affects brain neuroplasticity...
July 4, 2022: Nutrients
#78
REVIEW
Wen-Juan Fang, Fei Zheng, Lin-Zhi Zhang, Wen-Hui Wang, Cheng-Chen Yu, Juan Shao, Yi-Jin Wu
Post-stroke dysphagia (PSD) is a common and costly complication of stroke and is associated with increased mortality, morbidity, and hospitalization. Although most patients can spontaneously resume swallowing, there are still many patients who do not recover and even die. Despite multiple advances in the acute treatment and secondary prevention of stroke, the effective treatment of PSD remains a neglected area. Studies have shown that repair mechanisms of neurostimulation techniques and increased cortical activity play an important role in the treatment of PSD...
June 4, 2022: Neurological Sciences
#79
JOURNAL ARTICLE
Ziyi Zhou, Nan Zhang, Tengfei Lin, Yun Song, Lishun Liu, Zhuo Wang, Yaping Wei, Jianping Li, Yan Zhang, Yong Huo, Hai Ma, Chonglei Bi, Chongqian Fang, Binyan Wang, Hao Zhang, Xianhui Qin, Xiaobin Wang, Huiyuan Guo, Xiping Xu
OBJECTIVE: The aim of this study was to investigate the relationship between 25-hydroxyvitamin D3 (25[OH]D3 ) and ischemic stroke and its potential modifying factors in rural Chinese adults. METHODS: This nested case-control study was drawn from the H-type Hypertension and Stroke Prevention and Control Project, a community-based, prospective, observational study. Plasma 25(OH)D3 was measured by liquid chromatography with tandem quadrupole mass spectrometry. All stroke records came from the Chinese Center for Disease Control and Prevention...
February 5, 2022: Nutrition
#80
JOURNAL ARTICLE
Shreeya S Navale, Anwar Mulugeta, Ang Zhou, David J Llewellyn, Elina Hyppönen
BACKGROUND: Higher vitamin D status has been suggested to have beneficial effects on the brain. OBJECTIVES: To investigate the association between 25-hydroxyvitamin D [25(OH)D], neuroimaging features, and the risk of dementia and stroke. METHODS: We used prospective data from the UK Biobank (37-73 y at baseline) to examine the association between 25(OH)D concentrations with neuroimaging outcomes (N = 33,523) and the risk of dementia and stroke (N = 427,690; 3414 and 5339 incident cases, respectively)...
August 4, 2022: American Journal of Clinical Nutrition
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