Giovanni Melioli, Clive Spenser, Giorgio Reggiardo, Giovanni Passalacqua, Enrico Compalati, Anthi Rogkakou, Anna Maria Riccio, Elisabetta Di Leo, Eustachio Nettis, Giorgio Walter Canonica
BACKGROUND: An in vitro procedure based on a microarray containing many different allergen components has recently been introduced for use in allergy diagnosis. Recombinant and highly purified allergens belonging to different allergenic sources (inhalants, food, latex and hymenoptera) are present in the array. These components can either be genuine or cross-reactive, resistant or susceptible to heat and low pH, and innocuous or potentially dangerous. A large number of complex and heterogeneous relationships among these components has emerged, such that sometimes these interactions cannot be effectively managed by the allergist...
2014: World Allergy Organization Journal