Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Jennifer B Levin, David J Moore, Farren Briggs, Mahboob Rahman, Jessica Montoya, Colin Depp, Douglas Einstadter, Kurt C Stange, Celeste Weise, Taylor Maniglia, Richard Barigye, Gracie Howard Griggs, Clara Adeniyi, Joy Yala, Martha Sajatovic
OBJECTIVE: Individuals with bipolar disorder (BD) have high rates of suboptimal medication adherence, medical illness, and premature mortality, largely from cardiovascular causes. This analysis examined the association between adherence to antihypertensive and BD medications and clinical symptoms in patients with BD and comorbid hypertension (HTN) from an ongoing trial to optimize adherence. METHOD: Inclusion criteria were a BD diagnosis, treatment with antihypertensives, adherence challenges, and poorly controlled HTN...
September 14, 2024: International Journal of Psychiatry in Medicine
#2
JOURNAL ARTICLE
Sunwoo Park, Hyukmin Kwon, Sangwook Park, Saeyoung Oh, Kiho Lee, Hayoon Lee, Seokwoo Kang, Dongmin Park, Jongwook Park
We designed and synthesized new indolocarbazole-triazine derivatives, 9-di-tert-butyl-5,7-bis(4-(4,6-diphenyl-1,3,5-triazin-2-yl)phenyl)-5,7-dihydroindolo[2,3-b]carbazole (2TRZ-P-ICz) and 3,9-di-tert-butyl-5,7-bis(5'-(4,6-diphenyl-1,3,5-triazin-2-yl)-[1,1':3',1″-terphenyl]-2'-yl)-5,7-dihydroindolo[2,3-b]carbazole (2TRZ-TP-ICz), as new bipolar host materials for red phosphorescent OLEDs. In the film state, 2TRZ-P-ICz and 2TRZ-TP-ICz exhibited photoluminescence maxima at 480 nm and 488 nm, respectively...
September 2, 2024: Materials
#3
JOURNAL ARTICLE
Gerard Anmella, Michele De Prisco, Jeremiah B Joyce, Claudia Valenzuela-Pascual, Ariadna Mas-Musons, Vincenzo Oliva, Giovanna Fico, George Chatzisofroniou, Sanjeev Mishra, Majd Al-Soleiti, Filippo Corponi, Anna Giménez-Palomo, Laura Montejo, Meritxell González-Campos, Dina Popovic, Isabella Pacchiarotti, Marc Valentí, Myriam Cavero, Lluc Colomer, Iria Grande, Antoni Benabarre, Cristian-Daniel Llach, Joaquim Raduà, Melvin McInnis, Diego Hidalgo-Mazzei, Mark A Frye, Andrea Murru, Eduard Vieta
Background : Bipolar disorder (BD) involves significant mood and energy shifts reflected in speech patterns. Detecting these patterns is crucial for diagnosis and monitoring, currently assessed subjectively. Advances in natural language processing offer opportunities to objectively analyze them. Aims : To (i) correlate speech features with manic-depressive symptom severity in BD, (ii) develop predictive models for diagnostic and treatment outcomes, and (iii) determine the most relevant speech features and tasks for these analyses...
August 23, 2024: Journal of Clinical Medicine
#4
JOURNAL ARTICLE
Diego Primavera, Cesar Aviles Gonzalez, Alessandra Perra, Goce Kalcev, Elisa Cantone, Giulia Cossu, Anita Holzinger, Mauro Giovanni Carta, Federica Sancassiani
INTRODUCTION: Dementia, depression, and cardiovascular disease are major public health concerns for older adults, requiring early intervention. This study investigates whether a virtual reality cognitive remediation program (VR-CR) can improve cognitive function and depressive symptoms in older adults, and determines the necessary sample size for future studies. Integrated VR and CR interventions have shown promising outcomes in older adults with neurodegenerative and mental health disorders...
September 3, 2024: Healthcare (Basel, Switzerland)
#5
REVIEW
Beldisa Taflaj, Nunzia La Maida, Roberta Tittarelli, Annagiulia Di Trana, Ilaria D'Acquarica
New psychoactive substances (NPSs) are a heterogenous group of psychotropic molecules and diverted pharmaceutical drugs sold worldwide as legal substitutes for controlled drugs. The psychiatric consequences of NPS use are relatively unknown, although evidence of related psychotic symptoms has been described in the literature. We sought to summarize the available evidence on NPS-related psychiatric disorders, to facilitate the interpretation of the molecular mechanism underlying their specific pathologies. A literature search of Scopus, PubMed and Google Scholar was conducted including studies published between 2013 and 2024, in which a correlation between NPS consumption and psychiatric symptoms was reported...
August 31, 2024: International Journal of Molecular Sciences
#6
JOURNAL ARTICLE
Eglė Mickevičiūtė, Eivina Radzevičiūtė-Valčiukė, Veronika Malyško-Ptašinskė, Paulina Malakauskaitė, Barbora Lekešytė, Nina Rembialkowska, Julita Kulbacka, Joanna Tunikowska, Jurij Novickij, Vitalij Novickij
The phenomenon known as bipolar cancellation is observed when biphasic nanosecond electric field pulses are used, which results in reduced electroporation efficiency when compared to unipolar pulses of the same parameters. Basically, the negative phase of the bipolar pulse diminishes the effect of the positive phase. Our study aimed to investigate how bipolar cancellation affects Ca2+ electrochemotherapy and cellular response under varying electric field intensities and pulse durations (3-7 kV/cm, 100, 300, and 500 ns bipolar 1 MHz repetition frequency pulse bursts, n = 100)...
August 28, 2024: International Journal of Molecular Sciences
#7
JOURNAL ARTICLE
Dong Cao, Yafang Liu, Jinghong Mei, Shuailong Yu, Cong Zeng, Jing Zhang, Yujuan Li
BACKGROUND: Bipolar disorder (BPD) is a kind of manic and depressive phase alternate episodes of serious mental illness, and it is correlated with well-documented cortical brain abnormalities. Emerging evidence supports that autophagy dysfunction in neuronal system contributes to pathophysiological changes in neurological disease. However, the role of autophagy in bipolar disorder has rarely been elucidated. This study aimed to identify the autophagy-related gene as a potential biomarker Correlated to immune infiltration in BPD...
September 13, 2024: BMC Medical Genomics
#8
JOURNAL ARTICLE
Stefano Tambuzzi, Guido Travaini, Orsola Gambini, Federica Collini, Lorenzo Ginepro, Francesco Attanasio, Lorenzo Fregna, Federica Zucca, Domenico Di Candia, Alida Amadeo, Cristina Colombo, Alessio Battistini, Cristina Cattaneo
Suicide is one of the leading causes of death today, and among all mental illness, mood disorders account for one of the main risk factors. It is well known and proven that suicides are very common among people undergoing treatment and prescribed psychiatric medication. So far, however, there have only been a few studies dealing with this particular phenomenon. For this reason, autopsy patients who died by suicide, suffered from a mood disorder, and were known to be taking psychiatric medication at the time of death were selected for this study...
September 14, 2024: International Journal of Legal Medicine
#9
EDITORIAL
eBioMedicine
No abstract text is available yet for this article.
September 2024: EBioMedicine
#10
JOURNAL ARTICLE
Wenwen Xiang, Yu Shen, Yanping Li, Shenjian Chen, Qian Cao, Lijun Xu
BACKGROUND AND OBJECTIVE: Observational studies have suggested that mental disorders and cerebrovascular diseases (CVDs) may be risk factors for each other, but genetic evidence of a causal relationship is still lacking. We used Mendelian randomization (MR) studies to explore the causal relationship between mental disorders and CVDs from the genetic perspective. METHODS: To investigate the causal association between major depressive disorder (MDD), anxiety, attention deficit/hyperactivity disorder (ADHD), bipolar disorder and schizophrenia five kinds of mental disorders and CVDs using two-sample two-way MR analysis based on publicly available genome-wide association study (GWAS) data...
September 11, 2024: Journal of Affective Disorders
#11
JOURNAL ARTICLE
Anna Luisa Klahn, William Hedley Thompson, Imiele Momoh, Christoph Abé, Benny Liberg, Mikael Landén
Brain network hubs are highly connected brain regions serving as important relay stations for information integration. Recent studies have linked mental disorders to impaired hub function. Provincial hubs mainly integrate information within their own brain network, while connector hubs share information between different brain networks. This study used a novel time-varying analysis to investigate whether hubs aberrantly follow the trajectory of other brain networks than their own. The aim was to characterize brain hub functioning in clinically remitted bipolar patients...
September 3, 2024: Cerebral Cortex
#12
JOURNAL ARTICLE
Sara Massironi, Alessandro Pigoni, Elena Anna Maria Vegni, Laurie Keefer, Marla C Dubinsky, Paolo Brambilla, Giuseppe Delvecchio, Silvio Danese
BACKGROUND: Psychiatric disorders in patients with inflammatory bowel disease (IBD) represent a significant but uncertain facet of the disease, with unsolved questions regarding their overall magnitude, their impact on intestinal disease, and the whole burden of psychiatric manifestations. AIM: This systematic review summarizes the evidence on the prevalence and impact of psychiatric disorders, including depression, anxiety, bipolar disorder (BD), and schizophrenia, among patients with IBD...
September 12, 2024: Inflammatory Bowel Diseases
#13
JOURNAL ARTICLE
Michael Levine, Rachel Culbreth, Alexandra Amaducci, Diane P Calello, Joshua Shulman, Bryan Judge, Jennifer Love, Adrienne Hughes, Evan S Schwarz, Joseph Carpenter, Paul Wax, Kim Aldy, Alex J Krotulski, Barry K Logan, Jennie Buchanan, Jeffrey Brent, Christopher W Meaden, Robert G Hendrickson, Stephanie Abston, Shao Li, Sharan Campleman, Alex F Manini
INTRODUCTION: Opioid overdose deaths in the U.S. have risen dramatically in the past decade, largely due to the surge in illicitly manufactured fentanyl. Injection drug use is a known risk factor for HIV, further complicating the long-term consequences of opioid use. The baseline prevalence of HIV among adults in the US is 0.46 %. The primary purpose of this study was to determine the prevalence and risk factors of HIV among patients presenting to the emergency departments (ED) with an acute opioid overdose...
September 7, 2024: Drug and Alcohol Dependence
#14
REVIEW
Patricia Rubí-González, Karla Muáoz-Guzmán, Mariela Gatica-Saavedra, Gonzalo Navarrete Ríos, Marcela Rocha González, Pablo Fabregas-Soto, Giuliana Maccarini-Llorens
UNLABELLED: Lithium is a mood stabilizer recommended by most clinical guidelines as the gold standard to prevent relapses in the treatment of Bipolar Affective Disorder. It is highly effective, but unfortunately, it causes adverse effects at several levels, including the skin. AIM: To review the frequency, presentation, evolution, and management of adverse dermatologic effects caused by this drug. METHODS: We performed a narrative review using Scielo, Web of Science (WoS), and Google Scholar search engines, using keywords in Spanish and English...
December 2023: Revista Médica de Chile
#15
JOURNAL ARTICLE
Zhixing Chen, Minhui Yuan, Jingyi Lyu, Wenwei Yang, Zijie Ren, Jingfeng Li, Zhanpeng Zhao, Hailong Yang, Jing Shuai, Yanglong Hou
CoSb3 -based skutterudites have great potential as midtemperature thermoelectric (TE) materials due to their low cost and excellent electrical and mechanical properties. Their application, however, is limited by the high thermal conductivity and the degradation of TE performance at elevated temperatures, attributed to the adverse effects of bipolar diffusion. Herein, a series of Se y Co4 Sb12- x Te x compounds were successfully synthesized by combining a solid-state reaction and spark plasma sintering techniques to mitigate these challenges...
September 13, 2024: ACS Applied Materials & Interfaces
#16
JOURNAL ARTICLE
Michał Pastuszak, Wiesław Jerzy Cubała, Aleksander Kwaśny
BACKGROUND: Residual symptoms are frequently observed in a significant number of patients with depression, indicating an unmet need for effective management strategies to achieve functional recovery. OBJECTIVE: This observational study aimed to evaluate the impact of ketamine infusions on depressive symptoms in patients with bipolar disorder who continued their baseline psychotropic and chronic somatic treatments. METHODS: Datasets of the two consecutive real-world registries (NCT04226963 for 2019-2022; NCT05565352 from 2023 onward) for the tertiary reference center for psychiatry at the Medical University of Gdańsk (Poland) for the safety and tolerability of ketamine use in mood and anxiety disorders were retrospectively analyzed...
September 13, 2024: Drugs—Real World Outcomes
#17
JOURNAL ARTICLE
Simeone Andrulli, Antonietta Gigante, Michele Rossini, Pierluigi D'Angio', Gisella Vischini, Franca Luchetta, Filippo Aucella, Giovanni Valsecchi, Barbara Infante, Maria Giovanna Vario, Domenico Giannese, Antonio Granata, Elisabetta Moggia, Guido Gembillo, Rosario Cianci, Mario Bonomini, Flavia Manenti, Roberta Lazzarin, Brigida Di Renzo, Fulvia Zanchelli, Maurizio Garozzo, Massimo Manes, Yuri Battaglia, Raffaela Sciri, Marco De Fabritiis, Marco Quaglia, Gioacchino Li Cavoli, Enrica Gintoli, Maria Maddalena Conte, Maurizio Borzumati, Luisa Benozzi, Giovanna Pasquariello, Giovanni Andrulli, Marco Leoni, Giuseppe Seminara, Valentina Corbani, Gianmarco Sabiu, Arcangelo Di Maggio, Rosa Maria Pollastro, Loreto Gesualdo
The evaluation of estimated GFR (eGFR) is a pivotal staging step in patients with chronic kidney disease (CKD), and renal ultrasound plays an important role in diagnosis, prognosis and progression of CKD. The interaction between histopathological diagnosis and ultrasound parameters in eGFR determination has not been fully investigated yet. The study examined the results of native kidney biopsies performed in 48 Italian centers between 2012 and 2020. The primary goal was if and how the histopathological diagnosis influences the relationship between ultrasound parameters and eGFR...
September 13, 2024: Internal and Emergency Medicine
#18
JOURNAL ARTICLE
Covadonga Alvarez López, Aida González Paredes, Sonia Martínez Morales, Maria Teresa Aguilar Romero, Mónica Gutiérrez Simón, Jorge Fernández Parra, Alicia Hernández Gutiérrez
PURPOSE: To determine the effectiveness, safety, and participant satisfaction with endometrial ablation by bipolar energy (NovaSure® ) in the treatment of heavy menstrual bleeding (HMB), and to investigate factors associated with poorer outcomes. METHODS: Multicenter retrospective observational study based on medical record review of the outcomes related to endometrial ablation by the bipolar-energy technique procedure to treat HMB in the setting of three university teaching hospitals in Spain...
September 13, 2024: Archives of Gynecology and Obstetrics
#19
JOURNAL ARTICLE
Federica Arienti, Giovanni Casazza, Giulia Franco, Giulia Lazzeri, Edoardo Monfrini, Alessandro Di Maio, Roberto Erro, Paolo Barone, Filippo Tamma, Elena Caputo, Maria Antonietta Volontè, Laura Cacciaguerra, Andrea Pilotto, Alessandro Padovani, Cristoforo Comi, Luca Magistrelli, Franco Valzania, Francesco Cavallieri, Laura Avanzino, Roberta Marchese, Mariachiara Sensi, Giorgia Carroli, Roberto Eleopra, Roberto Cilia, Francesca Spagnolo, Alessandro Tessitore, Rosa De Micco, Roberto Ceravolo, Giovanni Palermo, Maria Chiara Malaguti, Leonardo Lopiano, Pierluigi Tocco, Chiara Sorbera, Michele Tinazzi, Andrea Ciammola, Donatella Ottaviani, Enza Maria Valente, Alberto Albanese, Fabio Blandini, Margherita Canesi, Angelo Antonini, Miryam Carecchio, Vincenza Fetoni, Carlo Colosimo, Daniele Volpe, Nicola Tambasco, Giovanni Cossu, Mario Zappia, Alessio Di Fonzo
BACKGROUND: Family history of Parkinson's disease (PD) is a common finding in PD patients. However, a few studies have systematically examined this aspect. OBJECTIVES: We investigated the family history of PD patients, comparing demographic and clinical features between familial PD (fPD) and sporadic PD (sPD). METHODS: A cross-sectional study enrolling 2035 PD patients was conducted in 28 Italian centers. Clinical data and family history up to the third degree of kinship were collected...
September 13, 2024: Movement Disorders Clinical Practice
#20
JOURNAL ARTICLE
Swati Jindal, Zhengnan Tian, Arijit Mallick, Sharath Kandambeth, Chen Liu, Prashant M Bhatt, Xixiang Zhang, Osama Shekhah, Husam N Alshareef, Mohamed Eddaoudi
Covalent organic frameworks (COFs) are viewed as promising organic electrode materials for metal-ion batteries due to their structural diversity and tailoring capabilities. In this work, firstly using the monomers N,N,N',N'-tetrakis(4-aminophenyl)-1,4-phenylenediamine (TPDA) and terephthaldehyde (TA), p-type phenylenediamine-based imine-linked TPDA-TA-COF is synthesized. To construct a bipolar redox-active, porous and highly crystalline polyimide-linked COF, i.e., TPDA-NDI-COF, n-type 1,4,5,8-naphthalene tetracarboxylic dianhydride (NDA) molecules are incorporated into p-type TPDA-TA-COF structure via postsynthetic linker exchange method...
September 13, 2024: Small
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
