Kai Zhu, Jingjing He, Tiantuo Chen, Xiyang Yu, Xiaorui He, Yilin Su
PURPOSE: To investigate the clinical value of enhanced recovery after surgery (ERAS) protocols for children with neuroblastoma (NB). METHODS: This retrospective review was conducted by using the electronic medical records of 48 children with retroperitoneal localized NB who underwent tumor resection (surgery for treatment, not diagnosis) between October 2016 and September 2021. The ERAS protocols for NB excision were implemented in 28 children (ERAS group), while 20 children received traditional care (TRAD group)...
June 1, 2023: Pediatric Surgery International
Maryanne Bourque, Dawn Marie E Recigno, Katie Preedy
Purpose: Discharging infants from the NICU is complex, requiring the coordination of multiple aspects of care. Patient follow-up includes transferring medical care to primary care providers (PCP) who initially may have to rely on parents/caregivers for details about the child's history and current needs. Improving communication between the NICU and primary care offices within this pediatric health system was a goal of the organization, especially as value-based care was launched. Design: A pilot program was introduced in which families, PCP, and NICU providers for medically complex infants were offered the opportunity to participate in video conference calls...
June 1, 2023: Neonatal Network: NN
James Evans, Dan Green, Faith Gibson, Graeme O'Connor, Julie Lanigan
BACKGROUND & AIMS: The intensive conditioning regimens administered during bone marrow transplant (BMT) frequently cause mucositis, gastrointestinal toxicity and reduced oral intake. Children are consequently at risk of malnutrition. First-line nutrition support is recommended as enteral nutrition (EN). Nasogastric tube (NGT) is the mainstay for administration. Gastrostomies provide an alternative, but there is limited evidence of their efficacy and safety in paediatric BMT. This study aimed to compare enteral tube complications and nutritional and clinical outcomes between children with a gastrostomy versus NGT throughout BMT...
June 2023: Clinical Nutrition ESPEN
Erica Chang, Dorothy Rowe, Ashish Patel, Brad Pasternak
Necrotizing enterocolitis (NEC) is a gastrointestinal condition usually found in premature neonates. Our case involves a full-term, 3-month-old male who was found to have pneumatosis after surgical repair of congenital cardiac defects. After cessation of enteral feeds, nasogastric tube decompression, and broad-spectrum antibiotics, breast milk was reintroduced 8 days after his procedure. Hematochezia developed, but repeat abdominal X-rays were normal with benign abdominal examinations, stable vital signs, and improved laboratory findings...
May 2023: JPGN reports
Tin Bo Nicholas Lam, Lauren Sussman, Benjamin Infantino
Esophageal thermal injury (ETI) is an uncommon occurrence in both children and adults. Therefore, little is known about the diagnosis and clinical course of patients suffering from these injuries. We present the case of an 11-year-old female with macrocephaly capillary malformation syndrome and developmental delay suffering from ETI after ingestion of a piece of hot butternut squash. Endoscopy revealed linear, white plaques consistent with thermal burns. Management involved respiratory support, local and systemic analgesia, antibiotics, and nasogastric tube feedings...
February 2023: JPGN reports
Gergely Balazs, Ivett Pecsi, Csilla Feher, Nora Katona, Tunde Kotorman, Balazs Kovacs-Paszthy, Mariann Marki, Istvan Pataki, Magdolna Riszter, Timea Rozsa, Gusztav Belteki, Tamas Kovacs, Gyorgy Balla, Andras Balajthy
BACKGROUND: Various flexible and semi-rigid catheter techniques have been reported for surfactant delivery during less invasive surfactant administration (LISA) in preterm infants. Data on the effect of catheter selection on procedural success rates and adverse events are limited. Our objective was to compare the rates of success and adverse events of LISA performed with nasogastric tube and semi-rigid catheter. METHODS: This was a post-hoc analysis of data from a quality improvement project...
May 8, 2023: Minerva pediatrics
B Ciacchini, G Di Nardo, M Marin, E Borali, M Caraccia, R Mogni, F Cairello, I Rabbone, G B Ferrero, A Pini Prato, E Felici
BACKGROUND: cardio-facio-cutaneous syndrome is a rare genetic disorder affecting less than 900 people in the world. It is mainly characterized by craniofacial, dermatologic and cardiac defects, but also gastroenterological symptoms may be present, ranging from feeding difficulties to gastroesophageal reflux and constipation.In this report we describe a case of this syndrome characterized by severe feeding and growth difficulties, with a particular focus on the management of gastroenterological complications...
2023: Frontiers in Pediatrics
Cecilia Rosso, Federica Turati, Alberto Maria Saibene, Elvira Verduci, Emanuela Fuccillo, Maria Chiara Tavilla, Mauro Magnani, Giuseppe Banderali, Monica Ferraroni, Eugenio De Corso, Giovanni Felisati, Carlotta Pipolo
BACKGROUND: Nasal cytology at birth and in the pediatric age is barely investigated regarding its association with the onset of common pediatric diseases. METHODS: We enrolled 241 newborns within their first 24 h of life, studying their nasal cellular composition and repeating this at 1 and 3 years of life. We collected anamneses of perinatal factors and external factors (parental smoking, passive smoking, breastfeeding), and the prevalence of otitis, rhinosinusitis, bronchitis, asthma, and allergy at all timepoints...
April 19, 2023: Journal of Personalized Medicine
Naveen Parkash Gupta, Zia S Ahmad, Rekha Mittal, Shyam Kukreja, Chetnanand Jha, Kapil Raheja
BACKGROUND: Optimal route of tube feeding in preterm babies is not known. OBJECTIVES: To compare the frequency of bradycardia and desaturation episodes/hours in hemodynamically stable preterm neo-nates (≤32 wk gestational age) fed by nasogastric vs orogastric route. DESIGN: Randomized controlled trial. PARTICIPANTS: Hemodynamically stable preterm neonates (≤32 wk gestational age) requiring tube feeding...
April 20, 2023: Indian Pediatrics
Esau Ogei, Jackson Kakooza, Catherine R Lewis
The management of the esophageal strictures that may result from caustic ingestion has evolved over time, from surgical to endoscopic management. Dilation with nasogastric tubes may be a valuable alternative in places with limited resources.
April 2023: Clinical Case Reports
Anna Fetta, Elisa Crotti, Elena Campostrini, Luca Bergonzini, Carlo Alberto Cesaroni, Francesca Conti, Veronica Di Pisa, Valentina Gentile, Maria Cristina Mondardini, Cesare Vezzoli, Lucio Giordano, Duccio Maria Cordelli
Febrile infection-related epilepsy syndrome (FIRES) is a prolonged refractory status epilepticus (SE) that develops among healthy individuals after a febrile infection. FIRES treatment is challenging due to its poor response to antiseizure medications (ASMs) and anesthetic drugs. The use of cannabidiol (CBD) as an adjunctive treatment has been suggested, albeit data about its role in the acute phase is lacking. This report describes the use of purified CBD in the acute phase of two pediatric cases of FIRES and their long-term outcome...
April 12, 2023: Epilepsia Open
Katherine M Tang, Patricia Hametz, William Southern
INTRODUCTION: Both respiratory syncytial virus (RSV) and influenza-associated lower respiratory tract infections (LRTI) cause serious respiratory infections in infants and toddlers. We aimed to assess the frequency of complex hospital courses among patients admitted with influenza versus RSV LRTI. METHODS: A retrospective cohort study was performed on admissions of children <2 years who were admitted for LRTI and tested positive for influenza or RSV from 2016 to 2019...
April 4, 2023: Pediatric Pulmonology
Wilhermine Jean Baptiste, Michelucia Casseus, Alka Dev, Patrice Joseph, Peter F Wright
During a 2-year period, eight cases of a distinct illness were seen among 1,424 neonates admitted to a newly established neonatal care unit in southern Haiti. The newborns presented with a picture of sepsis with shock, vomiting, hypotonia, lethargy, and abdominal distention. Five cases proved fatal and another case left the hospital against advice in extremis with little chance of survival. In each case, the illness was associated with a history of ingestion of teas that included castor oil, known as lok in Haitian Creole...
2023: Frontiers in Pediatrics
Ali Ceylan, Burak Mergen, Fahri Onur Aydin, Emre Avci, Yusuf Yildirim
PURPOSE: Evaluation of the results of sutureless amniotic membrane transplantation (AMT) using a pediatric nasogastric tube (NGT) for patients with acute Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) was aimed. METHODS: Twenty-six eyes of 13 patients with SJS/TEN with ocular involvement at a single tertiary care hospital between May 2020 and January 2022 were included in the study. An amniotic membrane was implanted to the ocular surface and conjunctival fornix using a modified symblepharon ring (MR) created by inserting NGT end-to-end...
March 21, 2023: Eye & Contact Lens
Mingzhu Liu, Mingxiang Zhang, Xiang Ren, Chen Liu, Huaijing Yu, Xiao-Liang Xu, Guo-Jian Ding, Tingliang Fu, Lei Geng, Fengchun Cheng
BACKGROUND: Anastomotic leakage is a life-threatening complication. Improvement of the anastomosis technique is needed, especially in patients with an inflamed edematous intestine. The aim of our study was to evaluate the safety and efficacy of an asymmetric figure-of-eight single-layer suture technique for intestinal anastomosis in pediatric patients. METHODS: A total of 23 patients underwent intestinal anastomosis at the Department of Pediatric Surgery of Binzhou Medical University Hospital...
2023: Frontiers in Surgery
Eva Sorensen, Connie Yu, Shu-Ling Chuang, Paola Midrio, Leopoldo Martinez, Mathew Nash, Ingo Jester, Amulya K Saxena
BACKGROUND: The aim of this multicenter retrospective study and literature review was to review management and outcomes of neonatal esophageal perforation (NEP). METHODS: Protocol data were collected from four European Centers on gestational age, factors surrounding feeding tube insertion, management and outcomes. RESULTS: The 5-year study period (2014-2018) identified eight neonates with median gestational age of 26 + 4 weeks (23 + 4-39) and median birth weight 636 g (511-3500)...
January 26, 2023: Children
Piotr Socha, Carsten Posovszky, Monika Szychta, Federica Viscogliosi, Luigi Martemucci, Urszula Grzybowska-Chlebowczyk, Valerie Perrot, Anne Kornowski, Marc A Benninga
OBJECTIVES: Many protocols and preparations are used for bowel cleansing before paediatric colonoscopy but few are based on scientific evidence. We evaluated efficacy, safety, tolerability, and patient preference of Oral Sulphate Solution (OSS) at 75% of the adult dose versus polyethylene glycol (PEG)-electrolyte solution in adolescents presenting for diagnostic colonoscopy. METHODS: Phase III, randomised, evaluator-blinded, non-inferiority study of OSS and PEG in adolescents aged 12-17 years...
February 24, 2023: Journal of Pediatric Gastroenterology and Nutrition
Shally Sharma, Aditi Sinha, Rohan Malik, Arvind Bagga
Guidelines recommend initiating supplemental enteral feeding through a nasogastric (NG) or gastrostomy tube (G-tube) in patients with chronic kidney disease who have inadequate oral intake despite repeated nutritional counseling. While G-tube placement is shown to improve both nutritional status and anthropometric indices of children with CKD in developed regions, information from developing countries is lacking. This retrospective report reviewed the impact of G-tube feeding on nutritional intakes and anthropometric parameters over a 1-y follow-up in 5 children with CKD-5D managed at one tertiary care center in India...
February 17, 2023: Indian Journal of Pediatrics
Hetal Rajnikant Gohil, Timothy Mwai Jumbi, David Kihiko Kuria, Francis Osawa
PURPOSE: To assess the neonatal referral and transport system for gastroschisis patients referred to a tertiary level hospital in Kenya. METHODS: This was a prospective cross-sectional study carried out at Kenyatta National Hospital (KNH) which recruited patients with gastroschisis using consecutive sampling approach. Data were collected on pre-, intra-transit factors, time and distance covered. Assessment was done using pre and intra transit factors as per the standard transport protocols in literature...
February 16, 2023: Pediatric Surgery International
Francesca Burlo, Davide Zanon, Eva Passone, Maristella Toniutti, Giuliano Ponis, Egidio Barbi, Valentina Taucar, Lucia De Zen
BACKGROUND: Children with medical complexity need complex assistance, that considerably affects caregivers' quality of life. They often need multiple medications, with a consequent relevant risk of errors or poor compliance. Galenic (or compounded) drugs are blended in the pharmacy's laboratory worldwide according to different rules and tailoring the patient's needs. While their use may sometimes simplify these therapies, little is known about parents' attitude about this issue. AIM: This study aimed at investigating the complexity of the daily therapy management and exploring the parents' opinions about galenic compounds...
March 2023: Palliative Medicine
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