Elton Dajti, Federico Ravaioli, Giulia Paiola, Sonia Volpi, Luigi Colecchia, Alberto Ferrarese, Luigina Vanessa Alemanni, Caterina Cusumano, Anna Rita Di Biase, Giovanni Marasco, Amanda Vestito, Davide Festi, Pierre-Emmanuel Rautou, Marco Cipolli, Antonio Colecchia
BACKGROUND AND AIMS: Porto-sinusoidal vascular disease (PSVD) has been described as the prominent pathology in liver explants of patients with cystic fibrosis (CF), but data outside the transplant setting are lacking. We aimed to investigate the prevalence of portal hypertension (PH) in CF-associated liver disease (CFLD) and develop an algorithm to classify liver involvement in CF patients. METHODS: This is a cross-sectional study of consecutive paediatric and adult patients in a tertiary centre between 2018 and 2019, who underwent ultrasound, liver (LSM) and spleen stiffness (SSM) measurement...
September 19, 2023: Liver International: Official Journal of the International Association for the Study of the Liver