keyword
https://read.qxmd.com/read/38665743/impact-of-alcohol-on-inflammation-immunity-infections-and-extracellular-vesicles-in-pathogenesis
#41
REVIEW
Jayaraman Tharmalingam, Prakash Gangadaran, Ramya Lakshmi Rajendran, Byeong-Cheol Ahn
Alcohol consumption is a widespread social activity with a complex and multifaceted impact on human health. Although moderate alcohol consumption has been associated with certain potential health benefits, excessive or chronic alcohol use can disrupt the body's immune balance, promote inflammation, and increase susceptibility to infections. The deleterious effects associated with alcohol toxicity include the loss of cell integrity. When cells lose their integrity, they also lose the capacity to communicate with other systems...
March 2024: Curēus
https://read.qxmd.com/read/38665699/integrated-rehabilitation-approach-utilizing-swiss-ball-training-mulligan-taping-and-mobilization-with-movement-for-simultaneous-management-of-sacroiliac-joint-dysfunction-and-lateral-ankle-sprain-in-a-badminton-athlete-a-case-study
#42
Saylee S Shedge, Swapnil U Ramteke, Subrat Samal
This case report details an integrated rehabilitation plan implemented for a professional badminton player who presented with issues of sacroiliac joint (SIJ) dysfunction and a lateral ankle sprain. The integrated approach aimed to address both musculoskeletal issues, considering their potential reciprocal influences on biomechanics and functional performance. The athlete underwent a thorough initial assessment, including clinical examination, imaging, and biomechanical analysis. Treatment began with targeted interventions for acute ankle sprain management, such as rest, ice, compression, and elevation (RICE) followed by progressive exercises to restore ankle stability and range of motion (ROM)...
March 2024: Curēus
https://read.qxmd.com/read/38665512/a-guide-to-troubleshooting-metal-sacrificial-anodes-for-organic-electrosynthesis
#43
REVIEW
Skyler D Ware, Wendy Zhang, Weiyang Guan, Song Lin, Kimberly A See
The development of reductive electrosynthetic reactions is often enabled by the oxidation of a sacrificial metal anode, which charge-balances the reductive reaction of interest occurring at the cathode. The metal oxidation is frequently assumed to be straightforward and innocent relative to the chemistry of interest, but several processes can interfere with ideal sacrificial anode behavior, thereby limiting the success of reductive electrosynthetic reactions. These issues are compounded by a lack of reported observations and characterization of the anodes themselves, even when a failure at the anode is observed...
April 24, 2024: Chemical Science
https://read.qxmd.com/read/38663270/micil-multiple-instance-class-incremental-learning-for-skin-cancer-whole-slide-images
#44
JOURNAL ARTICLE
Pablo Meseguer, Rocío Del Amor, Valery Naranjo
Artificial intelligence (AI) agents encounter the problem of catastrophic forgetting when they are trained in sequentially with new data batches. This issue poses a barrier to the implementation of AI-based models in tasks that involve ongoing evolution, such as cancer prediction. Moreover, whole slide images (WSI) play a crucial role in cancer management, and their automated analysis has become increasingly popular in assisting pathologists during the diagnosis process. Incremental learning (IL) techniques aim to develop algorithms capable of retaining previously acquired information while also acquiring new insights to predict future data...
April 9, 2024: Artificial Intelligence in Medicine
https://read.qxmd.com/read/38663082/sustainable-synthesis-of-bionanomaterials-using-non-native-plant-extracts-for-maintaining-ecological-balance-a-computational-bibliography-analysis
#45
REVIEW
Jaison Jeevanandam, João Rodrigues
Biological approaches via biomolecular extracts of bacteria, fungi, or plants have recently been introduced as an alternative approach to synthesizing less or nontoxic nanomaterials, compared to conventional physical and chemical approaches. Among these biological methods, plant-mediated approaches (phytosynthesis) are reported to be highly beneficial for large-scale, nontoxic nanomaterial synthesis. However, plant-mediated synthesis of nanomaterials using native plant extract can lead to bioprospecting issues and deforestation challenges...
April 24, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38660125/rehabilitation-management-of-patients-with-spinal-tuberculosis-review
#46
REVIEW
Jaouher Dhouibi, Amine Kalai, Amr Chaabeni, Ahlem Aissa, Zohra Ben Salah Frih, Anis Jellad
Spinal tuberculosis (ST) is a serious condition and a global health concern, accounting for a significant portion of musculoskeletal tuberculosis cases. It can lead to sever spinal and neurological complications. The management of ST involves a multidisciplinary approach, including medical treatment, surgery and rehabilitation. Rehabilitation is crucial through the course of the disease's and is tailored for each stage according to the patients' complaints, and clinical and functional complications. In the case of neurological issues due to spinal compression, rehabilitation aims at overcoming bed confinement complications, involving mobilization techniques, strengthening exercises and related vesico-sphincter disorders (urodynamics, catheterizing)...
2024: Med Int (Lond)
https://read.qxmd.com/read/38659645/is-increased-trunk-flexion-in-standing-up-related-to-muscle-weakness-or-pain-avoidance-in-individuals-with-unilateral-knee-pain-a-simulation-study
#47
JOURNAL ARTICLE
Eline Van Der Kruk, Thomas Geijtenbeek
The 'Timed Up and Go' test (TUG) is a widely used clinical tool for assessing gait and balance, relying primarily on timing as a measure. However, there are more observable biomechanical compensation strategies within TUG that are indicative of underlying neuromuscular issues and movement priorities. In individuals with unilateral knee osteoarthritis, an increased trunk flexion during TUG is a common phenomenon, often attributed to muscle weakness and/or pain avoidance. Unfortunately, it is difficult to differentiate between these underlying causes using experimental studies alone...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38659311/ethical-considerations-for-acutely-injured-and-future-burn-patients-who-smoke-while-on-home-oxygen-therapy
#48
JOURNAL ARTICLE
Kimberly H Khoo, Joshua S Yoon, Joseph A Carrese, Sheera F Lerman, C Scott Hultman, Julie A Caffrey
Home oxygen therapy (HOT) is prescribed to patients with pulmonary dysfunction to improve survival and quality of life. However, ignition of oxygen can lead to burns with significant morbidity and mortality. Providers who routinely treat this patient population face an ethical issue: balancing the obligation to provide beneficial treatment to a patient with the responsibility to protect that patient from suffering avoidable burn injuries. A thorough review was conducted to assess the literature regarding ethical considerations involved in managing patients who have been burned while smoking on HOT and who continue to smoke...
April 25, 2024: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://read.qxmd.com/read/38657495/experiences-of-living-kidney-donors-a-synthesis-of-unsolicited-patient-narratives
#49
REVIEW
Katya Loban, Saly El Wazze, Théa Milland, Lindsay Hales, Anita Slominska, Shaifali Sandal
INTRODUCTION: Despite the lauded benefits of living kidney donation, there is growing evidence of the challenges that living kidney donors (LKD) encounter in their donation trajectory and gaps in healthcare service provision. However, most of the evidence is derived from research conducted by clinicians or academic investigators. Significantly less attention has been devoted to analyzing unsolicited accounts of LKDs' experiences. METHODS: We conducted a review and synthesis of published unsolicited first-person narratives of LKDs and aimed to synthesize their experiences and identify care needs...
April 10, 2024: Transplantation Reviews
https://read.qxmd.com/read/38655392/novel-methods-to-monitor-the-biodegradation-of-polylactic-acid-pla-by-amycolatopsis-orientalis-and-amycolatopsis-thailandensis
#50
JOURNAL ARTICLE
Najwa Mat Yasin, Farlash Pancho, Md Yasin, Jan F M Van Impe, Simen Akkermans
Plastics are essential in modern life, but their conventional production is problematic due to environmental pollution and waste management issues. Polylactic acid (PLA) is a widely used bioplastic that is bio-based and biodegradable, making it a key player in the bioeconomy. PLA has been proven to be degradable in various settings, including aqueous, soil, and compost environments. However, monitoring and optimizing PLA biodegradation remains challenging. This study proposes methods to improve the quantification of PLA biodegradation by Amycolatopsis spp...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38655360/green-finance-and-high-pollution-corporate-compensation-empirical-evidence-from-green-credit-guidelines
#51
JOURNAL ARTICLE
Shiyu Li, Deqin Lin, Hongfei Xiao
With the increasing focus on Environmental, Social, and Governance (ESG) and Corporate Social Responsibility (CSR) on a global scale, stakeholders expect businesses to transform and enhance social responsibility. Over time, ESG and CSR have developed into vital performance metrics for businesses. Businesses are actively putting improvement measures into place in response to this new paradigm in order to stay competitive in this changing environment. China's dual commitment to CSR and sustainable development is in line with wider objectives, such as resolving issues of pay inequality...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38655032/automated-identification-of-atrial-fibrillation-from-single-lead-ecgs-using-multi-branching-resnet
#52
JOURNAL ARTICLE
Jianxin Xie, Stavros Stavrakis, Bing Yao
Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia, which is clinically identified with irregular and rapid heartbeat rhythm. AF puts a patient at risk of forming blood clots, which can eventually lead to heart failure, stroke, or even sudden death. Electrocardiography (ECG), which involves acquiring bioelectrical signals from the body surface to reflect heart activity, is a standard procedure for detecting AF. However, the occurrence of AF is often intermittent, costing a significant amount of time and effort from medical doctors to identify AF episodes...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38654156/the-role-of-mitochondrial-dynamics-and-mitophagy-in-skeletal-muscle-atrophy-from-molecular-mechanisms-to-therapeutic-insights
#53
REVIEW
Yuhang Lei, Mailin Gan, Yanhao Qiu, Qiuyang Chen, Xingyu Wang, Tianci Liao, Mengying Zhao, Lei Chen, Shunhua Zhang, Ye Zhao, Lili Niu, Yan Wang, Li Zhu, Linyuan Shen
Skeletal muscle is the largest metabolic organ of the human body. Maintaining the best quality control and functional integrity of mitochondria is essential for the health of skeletal muscle. However, mitochondrial dysfunction characterized by mitochondrial dynamic imbalance and mitophagy disruption can lead to varying degrees of muscle atrophy, but the underlying mechanism of action is still unclear. Although mitochondrial dynamics and mitophagy are two different mitochondrial quality control mechanisms, a large amount of evidence has indicated that they are interrelated and mutually regulated...
April 23, 2024: Cellular & Molecular Biology Letters
https://read.qxmd.com/read/38651373/proteomics-the-state-of-the-field-the-definition-and-analysis-of-proteomes-should-be-based-in-reality-not-convenience
#54
JOURNAL ARTICLE
Jens R Coorssen, Matthew P Padula
With growing recognition and acknowledgement of the genuine complexity of proteomes, we are finally entering the post-proteogenomic era. Routine assessment of proteomes as inferred correlates of gene sequences (i.e., canonical 'proteins') cannot provide the necessary critical analysis of systems-level biology that is needed to understand underlying molecular mechanisms and pathways or identify the most selective biomarkers and therapeutic targets. These critical requirements demand the analysis of proteomes at the level of proteoforms/protein species, the actual active molecular players...
April 19, 2024: Proteomes
https://read.qxmd.com/read/38650897/leveraging-and-exercising-caution-with-chatgpt-and-other-generative-artificial-intelligence-tools-in-environmental-psychology-research
#55
JOURNAL ARTICLE
Shuai Yuan, Fu Li, Matthew H E M Browning, Mondira Bardhan, Kuiran Zhang, Olivia McAnirlin, Muhammad Mainuddin Patwary, Aaron Reuben
Generative Artificial Intelligence (GAI) is an emerging and disruptive technology that has attracted considerable interest from researchers and educators across various disciplines. We discuss the relevance and concerns of ChatGPT and other GAI tools in environmental psychology research. We propose three use categories for GAI tools: integrated and contextualized understanding, practical and flexible implementation, and two-way external communication. These categories are exemplified by topics such as the health benefits of green space, theory building, visual simulation, and identifying practical relevance...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38650813/improving-healing-the-putative-effects-of-low-level-laser-therapy-for-ulcer-in-parkinson-s-disease
#56
Anam R Sasun, Pratik Phansopkar, Moh'd Irshad Qureshi
The progressive nature of Parkinson's disease and its associated motor and non-motor symptoms can lead to various complications when patients experience immobilization, exacerbating existing motor impairments and potentially giving rise to secondary health issues. The variability, progression, and management of tremors in PD can be challenging. Due to low bone mass density, patients with Parkinson's disease are susceptible to vitamin D deficiency. The lack of movement can worsen muscle rigidity and stiffness, leading to contractures and a decreased range of motion in joints...
March 2024: Curēus
https://read.qxmd.com/read/38650640/effectiveness-of-mangrove-sword-bean-food-bar-addressed-to-older-people-of-landslide-disaster-victims
#57
JOURNAL ARTICLE
Fatmah Fatmah
BACKGROUND: Older people require extra attention due to their reduced ability to prepare for disasters, as they adequately possess distinct needs. These groups necessitate uncomplicated, readily consumable, and palatable food options that fulfill their micronutrient needs. The objective of this research was to assess the effects of a snack bar enriched with api-api mangrove ( Avicennia marina ) and sword bean ( Canavalia ensiformis ) on the body weight and Body Mass Index (BMI) of older people individuals afflicted by a landslide event...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38649601/sustainable-adsorbent-frameworks-based-on-bio-resourced-materials-and-biodegradable-polymers-in-selective-phosphate-removal-for-waste-water-remediation
#58
REVIEW
Krishna Priyadarshini Das, Pooja Chauhan, Ulrike Staudinger, Bhabani Kumar Satapathy
Phosphorus to an optimum extent is an essential nutrient for all living organisms and its scarcity may cause food security, and environmental preservation issues vis-à-vis agroeconomic hurdles. Undesirably excess phosphorus intensifies the eutrophication problem in non-marine water bodies and disrupts the natural nutrient balance of the ecosystem. To overcome such dichotomy, biodegradable polymer-based adsorbents have emerged as a cost-effective and implementable approach in striking a "desired optimum-undesired excess" balance pertaining to phosphate in a sustainable manner...
April 22, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38644436/lithium-pre-storage-enables-high-initial-coulombic-efficiency-and-stable-lithium-enriched-silicon-graphite-anode
#59
JOURNAL ARTICLE
Yingjie Gao, Chenghao Cui, Zhikun Huang, Guoyu Pan, Yuanfan Gu, Yanan Yang, Fan Bai, Zhuang Sun, Tao Zhang
Application of silicon-based anode is significantly challenged by low initial Coulombic efficiency (ICE) and poor cyclability. Traditional pre-lithiation reagents often pose safety concerns due to their unstable chemical nature. Achieving a balance between water-stability and high ICE in prelithiated silicon is a critical issue. Here, we present a lithium-enriched silicon/graphite material with an ultra-high ICE of ≥110% through a high-stable lithium pre-storage methodology. Lithium pre-storage prepared a nano-drilled graphite material with surficial lithium functional groups, which can form chemical bonds with adjacent silicon during high-temperature sintering...
April 21, 2024: Angewandte Chemie
https://read.qxmd.com/read/38643764/global-cognition-gender-and-level-of-education-predict-dual-task-gait-speed-variability-metrics-in-older-adults
#60
JOURNAL ARTICLE
Paul W Kline, Faisal D Shaikh, Jaclyn E Tennant, Renee Hamel, Lisa A Zukowski
INTRODUCTION: To determine if demographic variables and measures of cognitive function, functional mobility, self-reported balance self-efficacy, and self-reported physical activity can predict gait speed variability during single-task walking (STgscv), during cognitive-motor dual-tasking (DTgscv), and dual-task effect on gait speed variability (DTEgscv) in older adults. METHODS: In 62 older adults, demographics were recorded and cognitive function (including the Montreal Cognitive Assessment, MoCA), functional mobility, balance self-efficacy (Activity-Specific Balance Confidence Scale, ABC), and self-reported physical activity (Physical Activity Scale for the Elderly, PASE) were assessed...
April 20, 2024: Gerontology
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