Ad Soyad, Yeşim Yıldız, Burcu Öztürk Şahin, Mert Can Demir, Şerife Demir, Beyza Çiftci, Nurdan Köktürk, Tansu Ulukavak Çiftçi, Ahmet Selim Yurdakul, Nilgün Yılmaz Demirci, Müge Aydoğdu, Murat Dizbay, İpek Kıvılcım Oğuzülgen
No abstract text is available yet for this article.
September 2023: Tüberküloz Ve Toraks
Seher Satar, Mustafa Engin Şahin, Pınar Ergün
No abstract text is available yet for this article.
September 2023: Tüberküloz Ve Toraks
Esra Karabiber, Özge Atik, Fatma Merve Tepetam, Bilgehan Ergan, Arzu İlki, Elif Karakoç Aydıner, Ahmet Özen, Fatma Özyer, Safa Barış
No abstract text is available yet for this article.
September 2023: Tüberküloz Ve Toraks
Elizabeth Zambrano Garza, Theresa Pauly, Yoonseok Choi, Rachel A Murphy, Wolfgang Linden, Maureen C Ashe, Kenneth M Madden, Jennifer M Jakobi, Denis Gerstorf, Christiane A Hoppmann
Older adults spend significant time by themselves, especially since COVID-19. Solitude has been associated with positive and negative outcomes. Partners need to balance social connectedness with time for one's own needs. This project examines how individual and partner solitude are associated with daily affect and relationship quality in dyads of older adults and a close other. One-hundred thirty-six older adults plus a close other rated their relationship quality and reported affect, solitude, and its characteristics (desired and bothersome) every evening for 10 days...
September 22, 2023: Applied Psychology. Health and Well-being
Lars Christian Lund, Martin Torp Rahbek, Peter Brown, Niels Obel, Jesper Hallas, Henrik Frederiksen
OBJECTIVES: We aimed to quantify the risk of death following a positive test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among individuals with haematological malignancies, stratified by virus variants and type of malignancy. METHODS: Using the Danish nationwide registries, we conducted a population-based cohort study among individuals who received a discharge diagnosis of haematological malignancies during the 5 years prior to testing positive for SARS-CoV-2 (February 2020-April 2023)...
September 22, 2023: European Journal of Haematology
Vanessa C Fong, Jennifer Baumbusch, Koushambhi Basu Khan
Coronavirus disease 2019 (COVID-19) created unprecedented challenges for everyone, but especially families of children with medical complexity (MC) who rely on a comprehensive range of health and social services in their daily lives. Yet despite this, there are limited studies exploring caregiver perspectives regarding access to health and social services during the pandemic. To address this gap, we aimed to explore how health and social services can better meet the needs of children with MC and their families...
September 22, 2023: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
Eva Oberle, Xuejun Ryan Ji, Maram Alkawaja, Tonje M Molyneux, Salima Kerai, Kimberly C Thomson, Martin Guhn, Kimberly A Schonert-Reichl, Anne M Gadermann
INTRODUCTION: This study examined profiles of social connectedness among early adolescents in grade 7 before the COVID-19 pandemic was declared (Winter 2020), and in grade 8 during the second Wave of the pandemic (Winter 2021). METHOD: Linked data from 1753 early adolescents (49% female) from British Columbia, Canada who completed the Middle Years Development Instrument survey in grades 7 and 8 were used. Participants reported on life satisfaction, depressive symptoms, and connectedness with peers and adults at home, school and in the community...
September 22, 2023: Journal of Adolescence
Matthew M Y Lee, Toru Kondo, Ross T Campbell, Mark C Petrie, Naveed Sattar, Scott D Solomon, Muthiah Vaduganathan, Pardeep S Jhund, John J V McMurray
BACKGROUND AND AIMS: Randomised controlled trials (RCTs) have assessed the effects of renin-angiotensin system (RAS) blockers in adults with COVID-19. This meta-analysis provides estimates of the safety and efficacy of treatment with (versus without) RAS blockers from these trials. METHODS: PubMed, Web of Science, and were searched (March 1-April 12, 2023). Event/patient numbers were extracted, comparing ACE inhibitor/ARB treatment, to no treatment, for the outcomes: intensive care unit (ICU) admission, mechanical ventilation, vasopressor use, acute kidney injury (AKI), renal replacement therapy (RRT), acute myocardial infarction, stroke/transient ischaemic attack, heart failure, thromboembolic events, and all-cause death...
September 22, 2023: European Heart Journal. Cardiovascular Pharmacotherapy
Ellie M Proussaloglou, Ekaterina L Koelliker, Jessica Laprise, Jennifer Scalia Wilbur, Katina Robison, Ashley Stuckey, Katherine Crawford
The COVID-19 outbreak in March 2020 resulted in a shift to telemedicine for cancer genetic counseling (GC). The objective of this study was to determine the effect of telehealth (TH) services on patient acceptance of recommended genetic testing, time to test completion, and follow-up test-disclosure GC appointment, as well as compliance with National Comprehensive Cancer Network (NCCN) recommendations for medical screenings when testing positive for a genetic variant. Data for this retrospective cohort study were collected at a tertiary-care academic health center using the electronic medical record and laboratory portal...
September 22, 2023: Journal of Genetic Counseling
Sotirios Papamatthaiou, James Boxall-Clasby, Edward J A Douglas, Pawel Jajesniak, Hadrien Peyret, June Mercer-Chalmers, Varun K S Kumar, George P Lomonossoff, Julien Reboud, Maisem Laabei, Jonathan M Cooper, Barbara Kasprzyk-Hordern, Despina Moschou
The recent COVID-19 outbreak highlighted the need for lab-on-chip diagnostic technology fit for real-life deployment in the field. Existing bottlenecks in multistep analytical microsystem integration and upscalable, standardized fabrication techniques delayed the large-scale deployment of lab-on-chip solutions during the outbreak, throughout a global diagnostic test shortage. This study presents a technology that has the potential to address these issues by redeploying and repurposing the ubiquitous printed circuit board (PCB) technology and manufacturing infrastructure...
September 22, 2023: Lab on a Chip
Niklas Worm Andersson, Emilia Myrup Thiesson, Ria Lassaunière, Jørgen Vinsløv Hansen, Anders Hviid
BACKGROUND: Reports suggest that the potential long-lasting health consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may involve persistent dysregulation of some immune populations, but the potential clinical implications are unknown. We investigated the associated risk of hospitalization due to non-coronavirus disease 2019 (COVID-19) infectious diseases following the postacute phase of SARS-CoV-2 infection. METHODS: By cross-linking data from the comprehensive Danish test and surveillance system for COVID-19 together with nationwide healthcare and demographic registers, we established a study cohort of 2 430 694 individuals aged ≥50 years, from 1 January 2021 to 10 December 2022, with no evidence of SARS-CoV-2 infection prior to study entry...
September 22, 2023: Clinical Infectious Diseases
Pei-Ping Jao, Hsin-Pei Feng, Wen-Chii Tzeng
COVID-19 has been a global pandemic for three years. Symptoms experienced by patients with this disease include fever, cough, fatigue, muscle pain, and diarrhea as well as mental health issues. The terms "coronasomnia" and "COVID-somnia" emerged in 2021 to describe sleep disorders attributable to stress associated with the COVID-19 pandemic. In this study, the concept analysis method proposed by Walker & Avant (2019) was utilized to define the concept of coronasomnia (Walker & Avant, 2019), with three key attributes identified, including COVID-related anxiety or depression; insomnia that emerges after the pandemic; and experiencing difficulty falling asleep, interrupted sleep, or early morning awakenings accompanied by difficulty returning to sleep...
October 2023: Hu Li za Zhi the Journal of Nursing
Mujie Yuan, Zeyu Han, Yan Liang, Yong Sun, Bin He, Wantao Chen, Fan Li
With the great success of coronavirus disease (COVID-19) messenger ribonucleic acid (mRNA) vaccines, mRNA therapeutics have gained significant momentum for the prevention and treatment of various refractory diseases. To function efficiently in vivo and overcome clinical limitations, mRNA demands safe and stable vectors and a reasonable administration route, bypassing multiple biological barriers and achieving organ-specific targeted delivery of mRNA. Nanoparticle (NP)-based delivery systems representing leading vector approaches ensure the successful intracellular delivery of mRNA to the target organ...
September 22, 2023: Biomaterials Research
Shih-Chieh Liao, Miau-Rong Lee, Yung-Lin Chen, Hank Szuhan Chen
BACKGROUND: Due to COVID-19, face-to-face service activities in service-learning courses have become unfeasible. To address this challenge, this study aims to integrate project-based learning into medical education's service-learning curriculum. This study also seeks to evaluate the effectiveness of this instructional approach and identify factors that influence its success. METHODS: A total of 135 first-year medical students enrolled in a mandatory 1-credit service-learning course were recruited...
September 22, 2023: BMC Medical Education
Songhui You, Antonio Cicchella
PURPOSE: April-May 2021 Shanghai city was under strict lockdown. Soccer players suffered from the restrictions, being unable to train and have a social life. The aim of this study was to compare differences in daytime sleepiness between genders and qualification levels in a cohort university Chinese soccer player under 0 Covid policy restrictions in the urban area of Shanghai. METHODS: 491 questionnaires of Epworth Sleepiness Scales (ESS) were compiled online by male and female Soccer Students (SS), Semi-Professional players (SP) and Professional Players (PP) during the ongoing restriction measures post Shanghai lockdown...
September 22, 2023: BMC Sports Science, Medicine and Rehabilitation
Akira Uchiyama, Shunhei Yamashina, Toshifumi Sato, Satoshi Sakuma, Yuichi Tomiki, Hiroyuki Isayama, Akihito Nagahara, Kenichi Ikejima
BACKGROUND: Endoscopy is an important form of clinical gastroenterology education because it gives students the opportunity to learn about diagnosis procedures and even treatment. During the COVID-19 pandemic, medical students were observed from outside the endoscopy room due to the risk of airborne infection. In this study, we investigated the efficacy of combining endoscopy education with doctor's-eye-view videos of the procedure obtained using live-action cameras (GoPro®). METHODS: From February to May 2021, endoscopists wore GoPro Hero8 cameras on their heads to display a doctor's-eye view video outside the room...
September 22, 2023: BMC Medical Education
Nicola Ughi, Davide Paolo Bernasconi, Francesca Del Gaudio, Armanda Dicuonzo, Alessandro Maloberti, Cristina Giannattasio, Paolo Tarsia, Giovanna Travi, Francesco Scaglione, Fabrizio Colombo, Michaela Bertuzzi, Antonella Adinolfi, Maria Grazia Valsecchi, Claudio Rossetti, Oscar Massimiliano Epis
BACKGROUND AND OBJECTIVES: Remdesivir is an antiviral agent, which was shown to be safe and effective in treating early COVID-19, but its favourable impact in hospitalised patients with non-critical disease is still under investigation. The present study aimed to assess the effectiveness and safety of remdesivir as a treatment for hospitalised patients with COVID-19 by a propensity score analysis of observational data. METHODS: In this monocentric retrospective cohort study, the effectiveness and safety of a 5-day course of remdesivir (200 mg intravenously at Day 1, then 100 mg from Days 2-5) in association with the standard of care were assessed in comparison with the standard of care only...
September 22, 2023: Clinical Drug Investigation
Rebecca Owen, Ruth E Ashton, Lindsay Skipper, Bethan E Phillips, James Yates, Callum Thomas, Francesco Ferraro, Tom Bewick, Kate Haggan, Mark A Faghy
PURPOSE: The complexity of long COVID and its diverse symptom profile contributes to unprecedented challenges for patients, clinicians, and healthcare services. The threat of long COVID remains ignored by Governments, the media and public health messaging, and patients' experiences must be heard through understanding of the lived experience. This study aimed to understand the lived experience of those living with long COVID. METHODS: An online web-based survey was designed using Patient and Public Involvement and Engagement (PPIE) to increase understanding of the lived experiences of long COVID, and was distributed through PPIE groups, social media, and word of mouth...
September 22, 2023: Quality of Life Research
Padmamalini Mahendradas, Sai Bhakti Mishra, Rohini Sangoram, Sanjay Srinivasan, Ankush Kawali, Aditya Patil, Rohit Shetty
BACKGROUND: Immunologic and inflammatory adverse effects following vaccination against COVID-19 are being reported. While some reactions may develop denovo others concern its immunogenic effect in patients with pre-existing inflammatory conditions. METHODS: Retrospective consecutive patients diagnosed with ocular inflammatory manifestations within 8 weeks of receiving COVID-19 vaccination who presented to a tertiary eye care centre in South India. RESULTS: Ninety-eight eyes of 67 patients presenting with ocular inflammatory manifestations within 8 weeks following COVID-19 vaccination were studied...
September 23, 2023: Journal of Ophthalmic Inflammation and Infection
Arindam Nandi, Nicole Haberland, Meredith Kozak, Thoại D Ngô
The COVID-19 pandemic disrupted education delivery around the world, with school closures affecting over 1.6 billion students worldwide. In India, schools were closed for over 18 months, affecting 248 million students. This study estimates the effect of the pandemic on adolescent literacy and schooling outcomes in India. We used data from the National Family Health Survey. (NFHS-5) which covered 636,699 households across all districts of India from June 2019 to April 2021. We considered 15-17 year old adolescents who were surveyed after March 2020 as the post-COVID group while those surveyed earlier were included in the pre-COVID group...
September 22, 2023: NPJ Science of Learning
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