Camilla Mattiuzzi
To the Editors, Tzeferakos et al. highlighted that drugs of abuse consumption may have substantially varied during the coronavirus disease 2019 (COVID-19) pandemic.1 To provide additional insights on this matter, we accessed Google Trends (Google Inc. Mountain View, CA, US) using the keywords "cannabis," "cocaine," and "heroin" under the specification "drug" (and thereby overcoming potential language differences), setting the geographical location to either "United States" (US) or "worldwide", within the past 5 years (i...
November 24, 2022: Psychiatrikē, Psychiatriki
Fragiskos Gonidakis
COVID-19 pandemic and its socio-economic consequences have been influencing considerably the Greek population and especially those people that are vulnerable or are actually suffering from a mental disorder. Considering eating disorders (ED) there are reports of a number of factors that increase the stress experienced by patients. The most important of them are:1 A. Quarantine and house confinement. Many ED patients report poor relationships with other family members or in some cases falling victims of some type of abusive behavior by other family members...
November 17, 2022: Psychiatrikē, Psychiatriki
Eugenia Triantafillou, Panagiotis Tsellos, Nikos Christodoulou, Chara Tzavara, Irina Mrvoljak-Theodoropoulou, George N Christodoulou
This study examines the associations of the COVID -19 pandemic stressors with mental health and quality of life (QoL) of the general population in different demographic areas of Athens. The random sample of the study consisted of 602 participants, 389 (64,6%) women and 213 (35,4%) men residing in Attica (Greece). It was conducted with telephone interviews during the first wave of the pandemic. The instruments used were: World Health Organization Quality of Life Instrument (WHOQOL-BREF), Depression Anxiety Stress Scale (DASS - 21), Body Vigilance Scale (ΒVS), Dimensional Obsessive-Compulsive Scale (Category 1: contamination obsessions -decontamination compulsions) (DOCS) and a set of socio-demographic data and questions on stressors related to the COVID-19 outbreak...
November 17, 2022: Psychiatrikē, Psychiatriki
Briony Shaw, Jake Shortt, Michael Low, Benjamin Rogers, Zane Kaplan, Pasquale Fedele, Gareth Gregory, Shahla Vilcassim, Michael Gilbertson, George Grigoriadis, Stephen Opat
Coronavirus disease 2019 (COVID-19) infection in patients with haematological neoplasms has been associated with increased mortality; however, many studies in this patient group were reported early in the pandemic. The authors evaluated outcomes of COVID-19 infection in patients with haematological conditions following widespread vaccination, newer viral variants and increasingly effective antiviral therapies. A 4% mortality rate was found and contemporary risk factors for hospitalisation including older age, nonvaccination or partial COVID-19 vaccination status and infection with non-Omicron strain were identified...
November 27, 2022: Internal Medicine Journal
Amandeep Sahota, Andy Tien, Janis Yao, Elizabeth Dong, John Herald, Sarah Javaherifar, Jonathan Neyer, Jennifer Hwang, Roland Lee, Tse-Ling Fong
BACKGROUND: Solid organ transplant recipients (SOTr) are at increased risk for severe disease from coronavirus disease 2019 (COVID-19) compared with non-SOTr. METHODS: We performed a retrospective cohort study between March 1, 2020, and March, 30, 2021, in an integrated healthcare system with 4.3 million members aged ≥18 y including 5126 SOTr. Comparisons in COVID-19 mortality, hospitalization, and incidence were made between SOTr and non-SOTr, and between different SOTr organs...
December 1, 2022: Transplantation
Mats Brännström, Stefan G Tullius, Jiri Fronek, Sara Y Brucker
Uterus transplantation (UTx) is currently the only available treatment for absolute uterine factor infertility. The International Society of Uterus Transplantation (ISUTx) was formally founded in 2017 and joined the Transplantation Society as a formal section in 2021. The Third International Congress of the ISUTx was held in Tübingen, Germany, in October 2021, as a hybrid meeting, attended virtually by about 450 delegates and in person by 35 delegates. This report summarizes the Tübingen meeting and complementary topics of relevance presented at the Second ISUTx state-of-the-art webinar meeting, held in Prague, in October 2020...
December 1, 2022: Transplantation
Jennifer Muschol, Cornelia Strauss, Christian Gissel
PURPOSE: This study aimed to analyze the utilization of cancer screenings in Germany before and during the COVID-19 pandemic in 2020. The objective of the analysis was to identify the population at particular risk and to derive recommendations for the future use of resources to prevent long-term deteriorations in health outcomes. METHODS: The analysis was conducted based on claims data of all preventive health services for 15,833,662 patients from the largest statutory health insurance fund in Germany...
November 27, 2022: Journal of Cancer Research and Clinical Oncology
Lajos Bálint, Péter Osváth, Attila Németh, Balázs Kapitány, Zoltán Rihmer, Péter Döme
INTRODUCTION: While suicide rates did not change (or decreased) in the first pandemic year (i.e., 2020) in the majority of countries, in Hungary the number of completed suicides rose significantly. OBJECTIVE: In our study, we investigated whether the unfavourable trend reversal of the Hungarian suicide rate following the outbreak of COVID-19 pandemic persisted in the second pandemic year. METHOD: We used an interrupted time-series analysis with Prais-Winsten regression, controlling for time and seasonal effects as well as autoregressive effects, to estimate the effect of the pandemic on the suicide rates of the Hungarian male, female and total populations in 2020 and 2021...
November 27, 2022: Orvosi Hetilap
Michael Shapiro, Yarden Yavne, Daniel Shepshelovich
No abstract text is available yet for this article.
November 2022: Israel Medical Association Journal: IMAJ
Izabella Elgardt, Or Carmi, Yair Levy
No abstract text is available yet for this article.
November 2022: Israel Medical Association Journal: IMAJ
Maamoun Basheer, Elias Saad, Faris Milhem, Dmitry Budman, Nimer Assy
Coronavirus disease 2019 (COVID-19) affects different people in different ways. Most infected people develop mild to moderate illness and recover without hospitalization. This case report presents a patient who had difficulty eradicating the corona virus due to being treated with rituximab, which depletes B lymphocytes and therefore disables the production of neutralizing antibodies. The regen-COV-2 antibody cocktail consists of two monoclonal antibodies, casirivimab and imdevimab. This cocktail successfully helped the patient's immune system eradicate the virus without auto specific severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody production...
November 2022: Israel Medical Association Journal: IMAJ
Pyper Olver, Mary Kathryn Bohn, Khosrow Adeli
Clinical laboratories play a vital role in the healthcare system. Objective medical data provided by clinical laboratories supports approximately 60-70% of clinical decisions, however, evidence supporting this claim is poorly documented and laboratories still lack visibility, despite their indisputable impact on patient care and public health. The International Federation for Clinical Chemistry and Laboratory Medicine (IFCC) Task Force on Outcome Studies in Laboratory Medicine (TF-OSLM) was recently developed to support directed research evaluating the role of laboratory medicine on clinical outcomes...
November 28, 2022: Clinical Chemistry and Laboratory Medicine: CCLM
Kristin Miller, Kelsey J Weitzel, Rebecca Bliss, Dana L Duren, Stephen D Ball, Breanne Baker
Exercise interventions targeting older adults often focus on acute changes, but lasting improvements require the adoption of long-term, independent exercise habits. This study aimed to assess the influence of eight-weeks of resistance training (SSSH) on clinically relevant fall-risk indicators in older adults and to evaluate if SSSH participation altered independent exercise engagement 12 months later. Sixty adults aged 50 yrs+ were randomised into SSSH, Walk, or Control groups and completed questionnaires and muscle strength and flexibility tests pre/post 8 weeks...
November 27, 2022: Journal of Sports Sciences
Fadime Ulupınar, Yasemin Erden
AIMS AND OBJECTIVES: The COVID-19 pandemic has caused an increase in the workload of nurses and changes in working conditions. Stress and the increase in workload during the COVID-19 pandemic had a negative effect on nurses' intention to leave. This study aimed to determine the current rate of intention to leave the job among nurses during the COVID-19 outbreak by conducting a rapid systematic review and meta-analysis. METHODOLOGY/METHODS: The review procedure was conducted by the PRISMA criteria...
November 27, 2022: Journal of Clinical Nursing
Salih Atakan Nemli, Ibrahim Yigit, Burcu Agrali, Deniz Gokengin, Bulent Turan
The COVID-19 pandemic has been profound impacts on mental and physical health of individuals with chronic diseases. Thus, it is important to understand the effects of the COVID-19 pandemic on people living with HIV. We aimed to assess the association between COVID-19-related knowledge and worry, HIV-related health practices and outcomes, and adherence to precautions related to COVID-19, and possible associations of these factors with HIV treatment outcomes (ART adherence and viral load). A cross-sectional survey was conducted between October 2020 and February 2021 among 291 PLWH at two large university hospital HIV clinics in Izmir, Turkey...
November 26, 2022: AIDS Care
Ricardo Lemes Gonçalves, Gabriel Augusto Pires de Souza, Mateus de Souza Terceti, Renato Fróes Goulart de Castro, Breno de Mello Silva, Romulo Dias Novaes, Luiz Cosme Cotta Malaquias, Luiz Felipe Leomil Coelho
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) quickly spread worldwide, leading coronavirus disease 2019 (COVID-19) to hit pandemic level less than 4 months after the first official cases. Hence, the search for drugs and vaccines that could prevent or treat infections by SARS-CoV-2 began, intending to reduce a possible collapse of health systems. After 2 years, efforts to find therapies to treat COVID-19 continue. However, there is still much to be understood about the virus' pathology...
November 26, 2022: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
Nicola Flor, Stefano Fusco, Ivana Blazic, Marcelo Sanchez, Ella Annabelle Kazerooni
Differently from computed tomography (CT), well-defined terminology for chest radiography (CXR) findings and standardized reporting in the setting of known or suspected COVID-19 are still lacking. We propose a revision of CXR major imaging findings in SARS-CoV-2 pneumonia derived from the comparison of CXR and CT, suggesting a precise and standardized terminology for CXR reporting. This description will consider asymptomatic patients, symptomatic patients, and patients with SARS-CoV-2-related pulmonary complications...
November 26, 2022: Emergency Radiology
Neal D Freedman, Liliana Brown, Lori M Newman, Jefferson M Jones, Tina J Benoit, Francisco Averhoff, Xiangning Bu, Konuralp Bayrak, Anna Lu, Brent Coffey, Latifa Jackson, Stephen J Chanock, Anthony R Kerlavage
Seroprevalence studies provide useful information about the proportion of the population either vaccinated against SARS-CoV-2, previously infected with the virus, or both. Numerous studies have been conducted in the United States, but differ substantially by dates of enrollment, target population, geographic location, age distribution, and assays used. This can make it challenging to identify and synthesize available seroprevalence data by geographic region or to compare infection-induced versus combined infection- and vaccination-induced seroprevalence...
November 26, 2022: Scientific Data
I'ah Donovan-Banfield, Rebekah Penrice-Randal, Hannah Goldswain, Aleksandra M Rzeszutek, Jack Pilgrim, Katie Bullock, Geoffrey Saunders, Josh Northey, Xiaofeng Dong, Yan Ryan, Helen Reynolds, Michelle Tetlow, Lauren E Walker, Richard FitzGerald, Colin Hale, Rebecca Lyon, Christie Woods, Shazaad Ahmad, Dennis Hadjiyiannakis, Jimstan Periselneris, Emma Knox, Calley Middleton, Lara Lavelle-Langham, Victoria Shaw, William Greenhalf, Thomas Edwards, David G Lalloo, Christopher J Edwards, Alistair C Darby, Miles W Carroll, Gareth Griffiths, Saye H Khoo, Julian A Hiscox, Thomas Fletcher
Molnupiravir is an antiviral, currently approved by the UK Medicines and Healthcare products Regulatory Agency (MHRA) for treating at-risk COVID-19 patients, that induces lethal error catastrophe in SARS-CoV-2. How this drug-induced mechanism of action might impact the emergence of resistance mutations is unclear. To investigate this, we used samples from the AGILE Candidate Specific Trial (CST)-2 (clinical trial number NCT04746183). The primary outcomes of AGILE CST-2 were to measure the drug safety and antiviral efficacy of molnupiravir in humans (180 participants randomised 1:1 with placebo)...
November 26, 2022: Nature Communications
Jia Rui, Jin-Xin Zheng, Jin Chen, Hongjie Wei, Shanshan Yu, Zeyu Zhao, Xin-Yi Wang, Mu-Xin Chen, Shang Xia, Ying Zhou, Tianmu Chen, Xiao-Nong Zhou
BACKGROUND: There is a raising concern of a higher infectious Omicron BA.2 variant and the latest BA.4, BA.5 variant, made it more difficult in the mitigation process against COVID-19 pandemic. Our study aimed to find optimal control strategies by transmission of dynamic model from novel invasion theory. METHODS: Based on the public data sources from January 31 to May 31, 2022, in four cities (Nanjing, Shanghai, Shenzhen and Suzhou) of China. We segmented the theoretical curves into five phases based on the concept of biological invasion...
November 26, 2022: Infectious Diseases of Poverty
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