Lane Viana Krejcová, João Bento-Torres, Daniel Guerreiro Diniz, Antonio Pereira, Manuella Batista-de-Oliveira, Andreia Albuquerque Cunha Lopes de Morais, Rosângela Figueiredo Mendes-da-Silva, Ricardo Abadie-Guedes, Ângela Amâncio Dos Santos, Denise Sandrelly Lima, Rubem Carlos Araujo Guedes, Cristovam Wanderley Picanço-Diniz
This study explores the multifaceted influence of litter size, maternal care, exercise, and aging on rats' neurobehavioral plasticity and dentate gyrus microglia dynamics. Body weight evolution revealed a progressive increase until maturity, followed by a decline during aging, with larger litters exhibiting lower weights initially. Notably, exercised rats from smaller litters displayed higher body weights during the mature and aged stages. The dentate gyrus volumes showed no significant differences among groups, except for aged sedentary rats from smaller litters, which exhibited a reduction...
May 15, 2024: Brain Sciences