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JOURNAL ARTICLE
Eunju Jin, Samuel Suk-Hyun Hwang
The experience of loneliness is universal and may have an adverse effect on neurocognitive functioning even at a younger age. Using a comprehensive neurocognitive functioning test (NCFT) battery, we examined the possible negative effects of loneliness on neurocognitive functioning in young adults. The high-loneliness and low-loneliness groups were screened using the UCLA Loneliness Scale v. 3, and measures pertaining to the domains of intelligence, attention, memory, executive function, and psychomotor functioning were tested and compared...
2024: Frontiers in Public Health
#2
JOURNAL ARTICLE
A A Pilipovich, O V Vorob'eva, S A Makarov
OBJECTIVE: Evaluation of nocturia and its relationship with clinical characteristics of Parkinson's disease (PD) and dopaminergic therapy. MATERIAL AND METHODS: One hundred and thirteen patients with PD of I-III Hoehn and Yahr stage (H&Y) were examined using the following scales: IPSS, including nocturia domain, UPDRS, Sch&En, PDQ-39, MMSE, FAB , BDI, STAI-S and STAI-T, PFS-16, NMSQuest, GDSS, GSRS, and orthotest. RESULTS: Nocturia was detected in 93 patients...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
#3
JOURNAL ARTICLE
Giorgio Maria Regnoli, Gioia Tiano, Barbara De Rosa
The Russian-Ukrainian conflict is affecting mental health even in communities that are not directly involved in the war; added to this is the escalating conflict in the Middle East and its dangerous spread, which brings the war back to the center of the contemporary social and economic horizon. The present study aims to explore the psychological impact of war in a sample of 310 Italian young adults (18-30 years; M = 22.0; SD = 2.6) while exploring the relationship between Fear of War and psychological distress and evaluating the mediating effects of Future Anxiety and Intolerance of Uncertainty in this relation...
March 26, 2024: European journal of investigation in health, psychology and education
#4
Iosif Lazaridis, Nick Patterson, David Anthony, Leonid Vyazov, Romain Fournier, Harald Ringbauer, Iñigo Olalde, Alexander A Khokhlov, Egor P Kitov, Natalia I Shishlina, Sorin C Ailincăi, Danila S Agapov, Sergey A Agapov, Elena Batieva, Baitanayev Bauyrzhan, Zsolt Bereczki, Alexandra Buzhilova, Piya Changmai, Andrey A Chizhevsky, Ion Ciobanu, Mihai Constantinescu, Marietta Csányi, János Dani, Peter K Dashkovskiy, Sándor Évinger, Anatoly Faifert, Pavel N Flegontov, Alin Frînculeasa, Mădălina N Frînculeasa, Tamás Hajdu, Tom Higham, Paweł Jarosz, Pavol Jelínek, Valeri I Khartanovich, Eduard N Kirginekov, Viktória Kiss, Alexandera Kitova, Alexeiy V Kiyashko, Jovan Koledin, Arkady Korolev, Pavel Kosintsev, Gabriella Kulcsár, Pavel Kuznetsov, Rabadan Magomedov, Mamedov Aslan Malikovich, Eszter Melis, Vyacheslav Moiseyev, Erika Molnár, Janet Monge, Octav Negrea, Nadezhda A Nikolaeva, Mario Novak, Maria Ochir-Goryaeva, György Pálfi, Sergiu Popovici, Marina P Rykun, Tatyana M Savenkova, Vladimir P Semibratov, Nikolai N Seregin, Alena Šefčáková, Mussayeva Raikhan Serikovna, Irina Shingiray, Vladimir N Shirokov, Angela Simalcsik, Kendra Sirak, Konstantin N Solodovnikov, Judit Tárnoki, Alexey A Tishkin, Viktov Trifonov, Sergey Vasilyev, Ali Akbari, Esther S Brielle, Kim Callan, Francesca Candilio, Olivia Cheronet, Elizabeth Curtis, Olga Flegontova, Lora Iliev, Aisling Kearns, Denise Keating, Ann Marie Lawson, Matthew Mah, Adam Micco, Megan Michel, Jonas Oppenheimer, Lijun Qiu, J Noah Workman, Fatma Zalzala, Anna Szécsényi-Nagy, Pier Francesco Palamara, Swapan Mallick, Nadin Rohland, Ron Pinhasi, David Reich
The Yamnaya archaeological complex appeared around 3300BCE across the steppes north of the Black and Caspian Seas, and by 3000BCE reached its maximal extent from Hungary in the west to Kazakhstan in the east. To localize the ancestral and geographical origins of the Yamnaya among the diverse Eneolithic people that preceded them, we studied ancient DNA data from 428 individuals of which 299 are reported for the first time, demonstrating three previously unknown Eneolithic genetic clines. First, a "Caucasus-Lower Volga" (CLV) Cline suffused with Caucasus hunter-gatherer (CHG) ancestry extended between a Caucasus Neolithic southern end in Neolithic Armenia, and a steppe northern end in Berezhnovka in the Lower Volga...
April 18, 2024: bioRxiv
#5
EDITORIAL
Edison Iglesias de Oliveira Vidal, Luiz Fernando Alvarenga Ribeiro, Marco Antonio de Carvalho-Filho, Fernanda Bono Fukushima
The high rates of depression, burnout, and increased risk of suicide among medical students, residents, and physicians in comparison with other careers signal a mental health crisis within our profession. We contend that this crisis coupled with the inadequate acquisition of interpersonal skills during medical education results from the interaction between a challenging environment and the mental capital of individuals. Additionally, we posit that mindfulness-based practices are instrumental for the development of major components of mental capital, such as resilience, flexibility of mind, and learning skills, while also serving as a pathway to enhance empathy, compassion, self-awareness, conflict resolution, and relational abilities...
April 19, 2024: World Journal of Psychiatry
#6
JOURNAL ARTICLE
V De Rubeis, L E Griffith, L Duncan, Y Jiang, M de Groh, L N Anderson
OBJECTIVES: During the COVID-19 pandemic, public health measures were used to reduce the spread of COVID-19; it is unknown whether people with chronic conditions differentially adhered to public health measures. The objectives of this study were to evaluate the association between chronic conditions and adherence and to explore effect modification by sex, age, and income. STUDY DESIGN: An analysis of data from the Canadian Longitudinal Study on Aging COVID-19 Questionnaires (from April to September 2020) was conducted among middle-aged and older adults aged 50-96 years (n = 28,086)...
April 22, 2024: Public Health
#7
JOURNAL ARTICLE
Elizaveta Ermakova, Kseniia Shaidullova, Oleg Gafurov, Alsu Kabirova, Dinara Nurmieva, Guzel Sitdikova
OBJECTIVES: Investigation of chronic homocysteine action on the excitability and N-methyl-D-aspartate (NMDA) sensitivity of the peripheral trigeminovascular system of rats. BACKGROUND: Migraine is a neurological disease that affects 15%-20% of the general population. Epidemiological observations show that an increase of the sulfur-containing amino acid homocysteine in plasma-called hyperhomocysteinemia-is associated with a high risk of migraine, especially migraine with aura...
April 22, 2024: Headache
#8
JOURNAL ARTICLE
Stine Nygård, Ingela Lundin Kvalem, Bente Træen
It is widely reported that image-based sexual abuse (IBSA) victimization is linked to a wide range of detrimental outcomes, including anxiety, depression, and suicidal ideation. However, knowledge about what shapes victims' experiences remains limited. To explore underlying mechanisms of harm in IBSA incidents, the present study drew on the concept of appraisal to elucidate the various meanings that victims attach to IBSA. For this purpose, we carried out a reflexive thematic analysis of 20 individual in-depth interviews with young male and female victims (ages 16-26) of IBSA...
April 17, 2024: Journal of Sex Research
#9
JOURNAL ARTICLE
Omar Gammoh, Osama Abo Al Rob, Abdelrahim Alqudah, Ahmed Al-Smadi, Mohamad Obada Dobain, Reham Zeghoul, Alaa A A Aljabali, Mervat Alsous
BACKGROUND: Dysmenorrhea is wide spread gynecological disorder among that affect the quality of life of women world wide. The current study aims to examine whether war displacement, mental health symptoms, and other clinical factors are associated with dysmenorrhea severity. METHODS: This is a cross-sectional case-control study recruiting two groups: displaced Syrian women and un-displaced local Jordanian women. Demographics and clinical details were recorded. The severity of dysmenorrhea was assessed using WaLIDD scale, the PHQ-9 scale was emplyed to assess depressive symptoms, anxiety was assessed using the GAD-7 scale, and insomnia was assessed using the ISI-A scale...
2024: AIMS Public Health
#10
JOURNAL ARTICLE
Eiji Kitamura, Naomi Kanazawa, Takahiro Iizuka, Kazutoshi Nishiyama
One characteristic of migraine is recurrent headache attacks, which are known to be induced by changes in climatic variables such as atmospheric pressure, humidity, and outside temperature. However, the relationship between temperature changes and migraine remains unclear. Therefore, we investigated the relationship between body temperature changes and cortical spreading depression (CSD) using KCl-induced rat models of CSD. We initially induced CSD under controlled conditions at a room temperature of 28°C on an operating table maintained at 37°C...
April 12, 2024: Neuroscience Research
#11
JOURNAL ARTICLE
Michal Fila, Lukasz Przyslo, Marcin Derwich, Ezbieta Pawlowska, Janusz Blasiak
Focal cortical dysplasias are abnormalities of the cerebral cortex associated with an elevated risk of neurological disturbances. Cortical spreading depolarization/depression is a correlate of migraine aura/headache and a trigger of migraine pain mechanisms. However, cortical spreading depolarization/depression is associated with cortical structural changes, which can be classified as transient focal cortical dysplasias. Migraine is reported to be associated with changes in various brain structures, including malformations and lesions in the cortex...
April 1, 2024: Cerebral Cortex
#12
JOURNAL ARTICLE
Livia Lontai, Lívia Priyanka Elek, Fruzsina Balogh, Dorottya Angyal, Péter Pajkossy, Lorant Gonczi, Peter L Lakatos, Ákos Iliás
Background: Inflammatory bowel diseases (IBDs) are chronic conditions that negatively affect the patient's quality of life. With the spread of the biopsychosocial model, the role of mental health in the activity and course of inflammatory bowel disease is becoming more and more recognized. Our study aimed to assess the prevalence of anxiety and depression in IBD patients in our tertiary referral center and determine the predictive factors of these mental conditions. Methods: A total of 117 patients were included consecutively between 1 December 2021 and 28 February 2022...
March 29, 2024: Journal of Clinical Medicine
#13
JOURNAL ARTICLE
Olena Venger, Yuriy Mysula, Oleksandr Oliynyk, Olena Striepetova, Oleksii Kulivets
OBJECTIVE: Aim: To study the structure and characteristics of psychopathological symptoms in FM who left Ukraine as a result of the full-scale armed aggression of the Russian Federation against Ukraine, and internally displaced persons, in a comparative aspect. PATIENTS AND METHODS: Materials and Methods: Examination was performed in compliance with the principles of biomedical ethics, based on informed consent. Research was provided on the basis of the Ternopil Regional Clinical Psychoneurological Hospital...
2024: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
#14
JOURNAL ARTICLE
Wan-Yi Lin, Yu-An Chen, Kuang-Hua Huang, Tung-Han Tsai, Shwn-Huey Shieh
AIM: This study investigated the levels of depression and anxiety in nurses and nursing assistants working in long-term care facilities during the COVID-19 pandemic. We also explored the potential causes of depression and anxiety in nurses and nursing assistants working in long-term care facilities during the pandemic. BACKGROUND: The COVID-19 pandemic has had a considerable impact on long-term care facilities. The high infection and mortality rates for COVID-19 have resulted in an increased workload for caregivers...
April 5, 2024: International Nursing Review
#15
JOURNAL ARTICLE
Alice Geminiani, Claudia Casellato, Henk-Jan Boele, Alessandra Pedrocchi, Chris I De Zeeuw, Egidio D'Angelo
According to the motor learning theory by Albus and Ito, synaptic depression at the parallel fibre to Purkinje cells synapse (pf-PC) is the main substrate responsible for learning sensorimotor contingencies under climbing fibre control. However, recent experimental evidence challenges this relatively monopolistic view of cerebellar learning. Bidirectional plasticity appears crucial for learning, in which different microzones can undergo opposite changes of synaptic strength (e.g. downbound microzones-more likely depression, upbound microzones-more likely potentiation), and multiple forms of plasticity have been identified, distributed over different cerebellar circuit synapses...
April 4, 2024: PLoS Computational Biology
#16
JOURNAL ARTICLE
Jeong Hyun Lee, Vishal M Gohil, Pedram Heidari, Jessica L Seidel, Mohammad Zulkifli, Ying Wei, Yuhua Ji, Ali Daneshmand, Umar Mahmood, Clary B Clish, Vamsi K Mootha, Cenk Ayata
BACKGROUND: Mild chemical inhibition of mitochondrial respiration can confer resilience against a subsequent stroke or myocardial infarction, also known as preconditioning. However, the lack of chemicals that can safely inhibit mitochondrial respiration has impeded the clinical translation of the preconditioning concept. We previously showed that meclizine, an over-the-counter antivertigo drug, can toggle metabolism from mitochondrial respiration toward glycolysis and protect against ischemia-reperfusion injury in the brain, heart, and kidney...
April 4, 2024: Stroke; a Journal of Cerebral Circulation
#17
REVIEW
Ankita Hepat, Dipali Khode, Swarupa Chakole
Urbanization is a phenomenon that shows the expansion of urban areas in conjunction with industrial and economic progress. Rapid world urbanization is caused by the swift rise in urban residents as a proportion of the population. Efforts to examine the quality of urban life and urbanization as distinct risk factors for mental illness within specific age groups have been made. However, the issue remains contentious and largely unresolved. Urban mental health issues, such as substance abuse, fear of crime, poverty, and ethnicity, are associated with factors like depression, aggression, fear, sadness, and personality disorders...
March 2024: Curēus
#18
JOURNAL ARTICLE
Zobayer Ibne Zaid, Anika Tasnim, Md Maruf Haque Khan, Zubair Ahmed Ratan, Mohammad Tanvir Islam, M Atiqul Haque
PURPOSE: Since the coronavirus (COVID-19) was announced as being a global pandemic on 11 March, governments from all parts of the world declared a quarantine period, during which people were prohibited from leaving their homes (except for essential activities) to contain the spread of the virus. Since then, the population has faced different levels of restrictions (i.e., mobility, social activities) that limited participation in normal daily routines. Consequently, these restrictions may have adversely changed physical activity, diet, sleep patterns, and screen time or work routine...
2024: PloS One
#19
JOURNAL ARTICLE
Yuki Novia Nasution, Marli Yehezkiel Sitorus, Kamal Sukandar, Nuning Nuraini, Mochamad Apri, Ngabila Salama
Acute respiratory infection (ARI) is a communicable disease of the respiratory tract that implies impaired breathing. The infection can expand from one to the neighboring areas at a region-scale level through a human mobility network. Specific to this study, we leverage a record of ARI incidences in four periods of outbreaks for 42 regions in Jakarta to study its spatio-temporal spread using the concept of the epidemic forest. This framework generates a forest-like graph representing an explicit spread of disease that takes the onset time, spatio-temporal distance, and case prevalence into account...
April 1, 2024: Scientific Reports
#20
JOURNAL ARTICLE
Anna M Hewett, Susan E Johnston, Alison Morris, Sean Morris, Josephine M Pemberton
Inbreeding depression is of major concern in declining populations, but relatively little is known about its genetic architecture in wild populations, such as the degree to which it is composed of large or small effect loci and their distribution throughout the genome. Here, we combine fitness and genomic data from a wild population of red deer to investigate the genomic distribution of inbreeding effects. Based on the runs of homozygosity (ROH)-based inbreeding coefficient, FROH , we use chromosome-specific inbreeding coefficients (FROHChr ) to explore whether the effect of inbreeding varies between chromosomes...
March 28, 2024: Molecular Ecology
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