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JOURNAL ARTICLE
Limor Adler, Zorian Radomyslsky, Miri Mizrahi Reuveni, Eduardo Schejter, Ilan Yehoshua, Yakov Segal, Sara Kivity, Etti Naimi, Mor Saban
BACKGROUND: As populations age globally, effectively managing geriatric health poses challenges for primary care. Comprehensive geriatric assessments (CGAs) aim to address these challenges through multidisciplinary screening and coordinated care planning. However, most CGA tools and workflows have not been optimised for routine primary care delivery. OBJECTIVE: This study aimed to evaluate the impact of a computerised CGA tool, called the Golden Age Visit, implemented in primary care in Israel...
May 17, 2024: Family Medicine and Community Health
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JOURNAL ARTICLE
Kathleen L Grady, Mary Amanda Dew, Francis D Pagani, John A Spertus, Eileen Hsich, Melana Yuzefpolskaya, Brent Lampert, James K Kirklin, Michael Petty, Andrew Kao, Clyde Yancy, Justin Hartupee, Salpy V Pamboukian, Maryl Johnson, Margaret Murray, Tingqing Wu, Adin-Cristian Andrei
BACKGROUND: The quality-adjusted life year (QALY) measures disease burden and treatment, combining overall survival and health-related quality of life (HRQOL). We estimated QALYs in three groups of older patients (60-80 years) with heart failure (HF) who underwent heart transplantation (HT, with pre-transplant mechanical circulatory support [HT MCS] or HT without pre-transplant MCS [HT Non-MCS]) or long-term MCS (destination therapy). We also identified factors associated with gains in QALYs through 24 months follow-up...
May 16, 2024: Journal of Heart and Lung Transplantation
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JOURNAL ARTICLE
Valerie Dirjayanto, Carmen Martin-Ruiz, Graziella Pompei, Francesca Rubino, Vijay Kunadian
BACKGROUND: The prognostic significance of inflammatory markers on the long-term risk of major adverse cardiovascular and cerebrovascular events (MACCE) in older NSTEACS patients remains unclear. METHODS: NSTEACS patients aged 75 and older were recruited to the multicentre cohort study Improve Cardiovascular Outcomes in High-Risk PatieNts with Acute Coronary Syndrome (ICON1). Inflammatory markers including interleukin-6 (IL-6), myeloperoxidase (MPO), high-sensitivity C-reactive protein (hsCRP), fibrinogen and tumor necrosis factor-alpha (TNF-α) were collected at baseline...
May 16, 2024: International Journal of Cardiology
#44
JOURNAL ARTICLE
Saurav Basu, Vansh Maheshwari, Debolina Roy, Mahira Saiyed, Rutul Gokalani
BACKGROUND: The Indian Diabetes Risk Score (IDRS) is a simple tool to assess the probability of an individual having type 2 diabetes (T2DM) but its applicability in community-dwelling older adults is lacking. This study aimed to estimate the risk of T2DM and its determinants among older adults without prior diabetes (DM) using the IDRS, while also assessing its sensitivity and specificity in individuals with a history of diabetes. METHODS: We analyzed cross-sectional data from the Longitudinal Ageing Study in India (LASI) wave-1 (2017-18)...
May 16, 2024: Diabetes & Metabolic Syndrome
#45
MULTICENTER STUDY
Lei Liu, Chunyu He, Jiaxin Yang, Wenbo Chen, Yan Xie, Xiaofang Chen
BACKGROUND: In older stroke patients with frailty, nutritional deficiencies can amplify their susceptibility, delay recovery, and deteriorate prognosis. A precise predictive model is crucial to assess their nutritional risk, enabling targeted interventions for improved clinical outcomes. OBJECTIVE: To develop and externally validate a nutritional risk prediction model integrating general demographics, physical parameters, psychological indicators, and biochemical markers...
May 18, 2024: Aging Clinical and Experimental Research
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JOURNAL ARTICLE
Miharu Nakanishi, Marieke Perry, Rachele Bejjani, Satoshi Yamaguchi, Satoshi Usami, Jenny T van der Steen
OBJECTIVES: Cognitive impairment, pain and depressive symptoms are common and interrelated factors in older adults. However, the directionality and specificity of their association remains unclarified. This study explored whether these factors prospectively increase reciprocal risk and examined the longitudinal association between these factors and quality of life (QoL). METHODS: This study used longitudinal data from The Older Persons and Informal Caregivers Survey Minimal Data Set (TOPICS-MDS; the Netherlands)...
May 2024: International Journal of Geriatric Psychiatry
#47
JOURNAL ARTICLE
Ezra Pak-Harvey, Daniel Lubin, Amy Chen, Elizabeth Willingham
OBJECTIVES: Air quality has been shown to impact the rates of fungal infection of the airway, causing diseases such as acute invasive fungal rhinosinusitis (AIFRS), particularly in immunocompromised patients. We theorize that patients with hematologic malignancies in units with aging air handling units (AHUs) have a higher attack rate of AIFRS. METHODS: Retrospective chart review identified patients with hematologic malignancy and AIFRS in two distinct and equal time periods between 2013 and 2022, representing the presence of aging AHUs and new AHUs, respectively...
May 18, 2024: Laryngoscope
#48
COMPARATIVE STUDY
Michaela Kluckner, Florian K Enzmann, Wolfgang Hitzl, David Wippel, Alina Hold, Thomas Hölzenbein, Patrick Nierlich
BACKGROUND: Octogenarians are regarded as one of the frailest patient groups among the chronic limb-threatening ischaemia population with high perioperative morbidity and mortality rates. As a result, alternative vein bypass surgery in the absence of sufficient great saphenous vein is often not considered as a potential treatment option. The aim of this study was to compare the results of octogenarians undergoing alternative vein bypass surgery due to chronic limb-threatening ischaemia to younger patients...
May 8, 2024: BJS Open
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JOURNAL ARTICLE
Santi Sulandari, Rachel Coats, Taufik Taufik, Judith Johnson
OBJECTIVE: This study aimed to investigate perceptions of what it means to 'age well' and to explore similarities and differences between a Western and non-Western culture (Britain and Java). METHOD: Qualitative interviews explored how Javanese and British older adults defined ageing well, establishing the similarities and differences between cultures. Javanese (n=14) and British (n=15) adults aged 61-80 (mean age=68) participated. The data were analysed using reflexive thematic analysis and organized with NVivo...
May 18, 2024: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
#50
REVIEW
Johan Sanner, Jakob O Ström, Mia von Euler, Bente Thommessen, Brynjar Fure
BACKGROUND: Due to the rapid growth of the world´s oldest population, the number of older persons with stroke is expected to rise. Knowledge of stroke etiology is essential to offer personalized and equal health care across age groups. The present systematic review aimed to investigate the prevalence of etiological subtypes of ischemic and hemorrhagic stroke in older compared to younger people. METHODS: MEDLINE, Embase, Cochrane, Epistemonikos, and Cinahl were systematically searched for studies regarding etiological classification in people ≥80 years compared to those <80 years with ischemic or hemorrhagic stroke...
May 18, 2024: Journal of Geriatric Psychiatry and Neurology
#51
JOURNAL ARTICLE
Natalie Zaremba, Gilberte Martine-Edith, Patrick Divilly, Uffe Søholm, Melanie Broadley, Namam Ali, Evertine J Abbink, Bastiaan de Galan, Monika Cigler, Julia K Mader, Julie Brosen, Ulrik Pedersen-Bjergaard, Allan Vaag, Mark Evans, Eric Renard, Rory J McCrimmon, Simon Heller, Jane Speight, Frans Pouwer, Stephanie A Amiel, Pratik Choudhary
INTRODUCTION: Reporting of hypoglycaemia and its impact in clinical studies is often retrospective and subject to recall bias. We developed the Hypo-METRICS app to measure the daily physical, psychological, and social impact of hypoglycaemia in adults with type 1 and insulin-treated type 2 diabetes in real-time using ecological momentary assessment (EMA). To help assess its utility, we aimed to determine Hypo-METRICS app completion rates and factors associated with completion. METHODS: Adults with diabetes recruited into the Hypo-METRICS study were given validated patient-reported outcome measures (PROMs) at baseline...
May 17, 2024: Diabetic Medicine: a Journal of the British Diabetic Association
#52
COMPARATIVE STUDY
Mei-Wen Wang, Ya-Mei Chen
BACKGROUND: This study aimed to assess family function in home care for older adults. Understanding family dynamics is essential for providing quality care to older adults choosing to age in place. METHODS: In a cross-sectional study, 53 patients aged 65 or older receiving home care were evaluated, along with four home care nurses. The General Function of Family Assessment Device (FAD-GF) was used for self-assessment to examine family resources. RESULTS: Only 5...
May 17, 2024: BMC Public Health
#53
JOURNAL ARTICLE
Bowen Zhang, Jingrui Wang, Nan Liu, Weijia Liu, Ruihan Xi, Peixi Wang
BACKGROUND: Polypharmacy would increase the risk of adverse drug events and the burden of renal drug excretion among older people. Nevertheless, the association between the number of medication and the risk of chronic kidney disease (CKD) remains controversial. Therefore, this study aims to investigate the association between the number of medication and the incidence of CKD in older people. METHODS: This study investigates the association between the number of medications and CKD in 2672 elderly people (≥ 65 years older) of the community health service center in southern China between 2019 and 2022...
May 17, 2024: BMC Nephrology
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JOURNAL ARTICLE
C Pérez-Ingidua, A B Rivas-Paterna, C González-Perrino, E Aleo-Luján, A Ascaso-Del-Rio, L Laredo-Velasco, A Portolés-Pérez, E Vargas-Castrillón
BACKGROUND: Paediatric patients are especially prone to experiencing adverse drug reactions (ADRs), and the surgical environment gathers many conditions for such reactions to occur. Additionally, little information exists in the literature on ADRs in the paediatric surgical population. We aimed to quantify the ADR frequency in this population, and to investigate the characteristics and risk factors associated with ADR development. METHODS: A prospective observational study was conducted in a cohort of 311 paediatric patients, aged 1-16 years, admitted for surgery at a tertiary referral hospital in Spain (2019-2021)...
May 18, 2024: BMC Pediatrics
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JOURNAL ARTICLE
Gege Li, Zijun He, Jinjing Hu, Chongwu Xiao, Weichao Fan, Zhuodong Zhang, Qiuru Yao, Jihua Zou, Guozhi Huang, Qing Zeng
OBJECTIVES: Motoric cognitive risk syndrome (MCR) is a pre-dementia condition characterized by subjective complaints in cognition and slow gait. Pain interference has previously been linked with cognitive deterioration; however, its specific relationship with MCR remains unclear. We aimed to examine how pain interference is associated with concurrent and incident MCR. METHODS: This study included older adults aged ≥ 65 years without dementia from the Health and Retirement Study...
May 17, 2024: BMC Geriatrics
#56
JOURNAL ARTICLE
Jonas Ammundsen Ipsen, Bjarke Viberg, Lars T Pedersen, Eva Draborg, Inge Hansen Bruun
BACKGROUND: Hip fracture is very common and it has life-shattering consequences for older persons. After discharge the older persons need help with even basic everyday activities from formal and informal caregivers. In Scandinavia formal care are well-developed however the presence of informal caregivers likely reflect on the amount of formal care and wears on the informal caregivers. This study explore how often and how much informal care (IC) older persons receive after hip fracture...
May 17, 2024: BMC Geriatrics
#57
JOURNAL ARTICLE
Matthew I Sait, Rachel A Christie, Chantel Cox, Michele Board, Sarah Thomas, Cheryl O'Sullivan, Cheryl Davies, Dawn-Marie Walker, Michael Vassallo, E A Sadler, Mark Allen-Pick, Patrick Moore, Katherine Bradbury, Jane Murphy
BACKGROUND: Multidomain interventions in older adults offer the best opportunity to prevent, delay or reverse existing symptoms in the earlier stages of frailty and improve independence but can be costly, and difficult to deliver at scale. However, digital health interventions enable personalised care and empowerment through self-management of long-term conditions, used at any time and when combined with health coaching offer the potential to enhance well-being and facilitate the achievement of health-related goals...
May 16, 2024: BMJ Open
#58
JOURNAL ARTICLE
Shinbae Seo, Taekyu Kwon, Miyeon Shin, Hochoon Jeong, Mi Yu, Jongkyun Jeong, Changho Yu
BACKGROUND: Sarcopenia is a disease that has recently become an issue, and research on various assessment methods is being conducted based on guidelines published for the diagnosis of sarcopenia. However, most assessments are complex because the inspector must measure each device to collect data, or the elderly must directly manipulate and get assessment. OBJECTIVE: In this study, we developed an sarcopenia assessment system to assess and analyze various sarcopenia in one system...
April 18, 2024: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
#59
JOURNAL ARTICLE
Sameh Samir Elawady, Conor Cunningham, Hidetoshi Matsukawa, Kazutaka Uchida, Steven Lin, Ilko Maier, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M Starke, Marios-Nikos Psychogios, Edgar A Samaniego, Adam Arthur, Shinichi Yoshimura, Hugo Cuellar, Jonathan A Grossberg, Ali Alawieh, Daniele G Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S Park, Michael R Levitt, Waleed Brinjikji, Mark Moss, Travis Dumont, Richard Williamson, Pedro Navia, Peter Kan, Reade De Leacy, Shakeel Chowdhry, Mohamad Ezzeldin, Alejandro M Spiotta, Sami Al Kasab
BACKGROUND AND OBJECTIVES: This study aimed to compare outcomes of low Alberta Stroke Program Early Computed Tomography Score (ASPECTS) patients with stroke who underwent mechanical thrombectomy (MT) within 6 hours or 6 to 24 hours after stroke onset. METHODS: A retrospective cohort study was conducted using data from a large multicenter international registry from 2013 to 2023. Patients with low ASPECTS (2-5) who underwent MT for anterior circulation intracranial large vessel occlusion were included...
May 17, 2024: Neurosurgery
#60
JOURNAL ARTICLE
Slim Zarzissi, Firas Zghal, Mustapha Bouchiba, Haithem Rebai, Nadia Fekih, Mohamed Amine Bouzid
The aim of the study was to assess the impact of aging on neuromuscular fatigue and recovery. Ten young (23.08 ± 1.43 years) and older (61.19 ± 1.80 years) males performed an intermittent maximal isometric exercise with the knee extensors followed by 27 min of recovery. Maximal voluntary contraction (MVC), total work (W'), voluntary activation (VA), potentiated resting twitch (Ptw), and electromyography (EMG) were recorded and then analyzed. Peripheral and central fatigue following exercise were lower in old compared to young (- 29...
May 17, 2024: European Journal of Applied Physiology
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