keyword
https://read.qxmd.com/read/32468969/heart-rate-variability-in-the-course-of-chemotherapy-and-haematopoietic-stem-cell-transplantation-for-peadiatric-patients-with-haematological-malignancies
#1
Honami Kobayashi, Noriko Motoki, Saori Yokota, Ayako Kanai, Shoko Yamazaki, Masafumi Utsumi, Yozo Nakazawa
BACKGROUND: High-dose chemotherapy and haematopoietic stem cell transplantation are essential for patients with paediatric haematologic diseases, although cardiotoxicity remains a concern. Heart rate variability analysis can evaluate autonomic nervous function interactions with cardiac function. OBJECTIVE: This study aimed to characterise heart rate variability differences between patients undergoing chemotherapy and controls, and the effects of haematopoietic stem cell transplantation on the autonomic nervous system in patients with haematological malignancies...
May 29, 2020: Cardiology in the Young
https://read.qxmd.com/read/32296200/induction-remission-response-in-peadiatric-acute-lymphoblastic-leukaemia-lahore-protocol-versus-ukall-2011-interim-guidelines
#2
Safia Khan, Saadia Anwar, Muhammad Farooq Latif, Ayesha Farooq, Mahwish Faizan
OBJECTIVE: To compare the outcome of induction-remission in acute lymphoblastic leukaemia patients treated according to two different guidelines. METHODS: The descriptive retrospective cohort study was conducted at The Children's Hospital Lahore, Pakistan, and comprised clinical information sheets of acute lymphoblastic leukaemia patients from September 2014 to August 2015. Data regarding demographics, risk categorisation, rapid early response and induction-remission assessment was collected separately for Group 1 patients treated with Lahore protocol and Group 2 patients using United Kingdom acute lymphoblastic leukaemia-2011 interim guidelines...
April 2020: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/31571689/non-operating-room-anaesthesia-in-children
#3
REVIEW
Subrahmanyam Maddirala, Annu Theagrajan
Administration of sedation and/or anaesthesia to patients undergoing painful or uncomfortable procedures at off-site locations is referred to as non-operating room anaesthesia (NORA). Sedating/anaesthetising children in an unfamiliar environment, with the lack of support staff, nonavailability of choice of medication and equipment is often challenging. Studies have shown an increased risk of airway-related adverse events, complications, and even death outside the operating room locations. It is crucial to be familiar with the anatomical and physiological variations in children, well versed with the difficult airway algorithm and call for help early...
September 2019: Indian Journal of Anaesthesia
https://read.qxmd.com/read/30299526/paediatric-cerebral-palsy-prevalence-and-high-risk-factors-in-henan-province-central-china
#4
Junying Yuan, Jun Wang, Jieqiong Ma, Dengna Zhu, Zhenhuan Zhang, Jianan Li
OBJECTIVE: To evaluate the prevalence of, and risk factors for, cerebral palsy in Henan province, China. METHODS: The prevalence of cerebral palsy in children aged 0-6 years between September 2011 and September 2012 was investigated using a stratified-clustered-random sampling method. An age-, sex- , and residence-matched control group of typically developing children was recruited. Univariate analysis and multinomial logistic regression analysis were used to identify risk factors associated with cerebral palsy...
October 9, 2018: Journal of Rehabilitation Medicine
https://read.qxmd.com/read/29042917/viral-infections-neonatal-mortality-and-the-mystery-of-the-athenian-agora-an-interview-with-professor-of-anthropology-maria-liston
#5
Ioannis N Mammas, Demetrios A Spandidos
Although excavated almost 80 years ago, the infants' 'bone well' of the Athenian Agora in Athens, Greece and its contents were never thoroughly evaluated and published, until only recently, when a re-analysis of the whole excavation findings was performed. The well dates back to the third quarter of the 2nd century BC and contained at least 449 infants. The project, which explored the causes of neonatal mortality, found that one-third of infants' deaths were attributed to neonatal meningitis, based on the presence of bone disposition on the endocranial surface of the studied skulls...
October 2017: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/28871588/primary-pleuropulmonary-synovial-sarcoma-with-brain-metastases-in-a-paediatric-patient-an-unusual-presentation
#6
Pushpak Chandrakant Chirmade, Sonia Parikh, Asha Anand, Harsha Panchal, Apurva Patel, Sandip Shah
Primary lung neoplasms are rare in children. The most common primary lung malignancies in children are pleuropulmonary blastoma and carcinoid tumour. Synovial sarcoma (SS) accounts for approximately 1% of all childhood malignancies. In absolute terms, the SS of the lungs and pleura are extremely rare and pose a diagnostic difficulty. Soft tissue sarcomas usually have a high potential for metastases, however, metastasis to the brain is rare, even in widely disseminated disease, and it has been described only in 3 case reports previously...
2017: Advances in Respiratory Medicine
https://read.qxmd.com/read/28730300/health-related-quality-of-life-in-paediatric-patients-with-congenital-heart-defects-association-with-the-type-of-heart-defect-and-the-surgical-technique
#7
A Heusch, H J Kahl, K O Hensel, G Calaminus
The aim of the study was to investigate the impact of a number of surgical interventions for a various congenital cardiac defects (CHDs) on self-reported HRQoL. METHODS: Patients who had received corrective surgery of several congenital heart defects (surgical VSD closure, Fallot, TGA after atrial or arterial switch or Fontan-type circulation for univentricular AV-connection) were interviewed in the office of their home peadiatric cardiologist. HRQoL in children along 7 dimensions was assessed using a standardised questionnaire (PEDQoL); information on the medical case history of each respondent was also collected...
November 2017: Quality of Life Research
https://read.qxmd.com/read/28462653/management-of-ampullary-tumours-in-children-still-a-challenge
#8
P Fernandez-Eire, J L Vazquez Castelo, M Herreros Villaraviz, B Fernandez Caamaño, J Gonzalez-Carreró, F Ausania
This study describes the case of the youngest patient ever reported with ampullary adenoma. The incidence of ampullary adenomas in childhood is unknown. Endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound are used in adults to assess and treat these lesions, although there are no instruments designed specifically for use in young children. A six-year-old girl was admitted for abdominal pain, vomiting, pruritus and weight loss. Abdominal ultrasound showed biliary tree (8mm) and pancreatic duct dilatation (4mm)...
May 2017: Annals of the Royal College of Surgeons of England
https://read.qxmd.com/read/28172932/p351-do-self-selected-non-transitioned-referrals-from-peadiatric-services-have-lower-treatment-requirements
#9
O Shaikh, P Harvey, R Cooney, R Muhammed
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://read.qxmd.com/read/27895375/clinical-profile-treatment-and-survival-outcomes-of-peadiatric-germ-cell-tumours-a-pakistani-perspective
#10
Irfan Ul Islam Nasir, Muhammad Ijaz Ashraf, Nouman Ahmed, Muhammad Fahd Shah, Muhammad Taqi Pirzada, Amir Ali Syed, Abid Quddus Qazi
Germ Cell Tumours (GCTs) are rare tumours. Generally 80% are benign and 20% malignant with a bimodal age distribution. The retrospective study was conducted at Shaukat Khanum Cancer Hospital, Lahore, Pakistan, and comprised all paediatric patients below 18 years of age who received treatment for histology-proven GCT from 2006 to 2014. Of the 207 patients, 98(42.3%) were males and 109(52.7%) were females. The most common GCT was yolk sac tumour in 90(43.5%) children followed by mixed GCT in 40(19.3%) and dysgerminoma in 34(16...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/27525605/knowledge-attitude-and-practice-of-the-mothers-with-anemia-of-children-under-five-years-old-in-the-peadiatric-department-at-sylvanus-olympio-teaching-hospital-in-lom%C3%A3
#11
Koffi Mawuse Guedenon, Yawo Dzayissê Atakouma, Essossolim Macamanzi, Fidèle Comlan Dossou, Adama Dodji Gbadoe
BACKGROUND: Anemia remains a major cause of morbidity and mortality of children in Togo despite of prevention effort, due to the parents lack of implication. AIM: To determine the knowledges, attitudes and practices of mothers, with anemia ofchildren under five years old Methods : Knowledge Attitudes and Practice survey from the first of february to 31 ofmarch 2012, about an interview of a hundred mothers with children under 5, randomly selected in the consultation, vaccination waiting rooms and in the hospitalisation...
January 2016: La Tunisie Médicale
https://read.qxmd.com/read/27332258/improving-patients-experience-in-peadiatric-emergency-waiting-room
#12
Frederic Ehrler, Johan Siebert, Rolf Wipfli, Cyrille Duret, Alain Gervaix, Christian Lovis
When visiting the emergency department, the perception of the time spent in the waiting room before the beginning of the care, may influence patients' experience. Based on models of service evaluation, highlighting the importance of informing people about their waiting process and their place in the queue, we have developed an innovative information screen aiming at improving perception of time by patients. Following an iterative process, a group of experts including computer scientists, ergonomists and caregivers designed a solution adapted to the pediatric context...
2016: Studies in Health Technology and Informatics
https://read.qxmd.com/read/27030556/the-european-society-of-peadiatric-radiology-search-for-a-new-european-managing-editor
#13
(no author information available yet)
No abstract text is available yet for this article.
August 2015: Pediatric Radiology
https://read.qxmd.com/read/26849224/contralateral-noise-stimulation-delays-p300-latency-in-school-aged-children
#14
Thalita Ubiali, Milaine Dominici Sanfins, Leticia Reis Borges, Maria Francisca Colella-Santos
BACKGROUND AND OBJECTIVE: The auditory cortex modulates auditory afferents through the olivocochlear system, which innervates the outer hair cells and the afferent neurons under the inner hair cells in the cochlea. Most of the studies that investigated the efferent activity in humans focused on evaluating the suppression of the otoacoustic emissions by stimulating the contralateral ear with noise, which assesses the activation of the medial olivocochlear bundle. The neurophysiology and the mechanisms involving efferent activity on higher regions of the auditory pathway, however, are still unknown...
2016: PloS One
https://read.qxmd.com/read/26637841/exploring-behavioral-sleep-problems-in-children-with-adhd-and-comorbid-autism-spectrum-disorder
#15
Simone Thomas, Kate Lycett, Nicole Papadopoulos, Emma Sciberras, Nicole Rinehart
OBJECTIVE: This study (a) compared behavioral sleep problems in children with comorbid ADHD and autism spectrum disorder (ASD) with those with ADHD and (b) examined child/family factors associated with sleep problems. METHOD: Cross-sectional study comparison of 392 children with a confirmed ADHD diagnosis (ADHD+ASD, n=93, ADHD, n=299) recruited from 21 peadiatric practises in Victoria, Australia. Data were collected from parents. Key measures included the Child Sleep Habits Questionnaire (CSHQ)...
August 2018: Journal of Attention Disorders
https://read.qxmd.com/read/26254736/propofol-induced-rno-mir-665-targets-bcl2l1-and-influences-apoptosis-in-rodent-developing-hippocampal-astrocytes
#16
Wen-Chong Sun, Zuo-Di Liang, Ling Pei
Propofol exerts neurotoxic effects on the developing mammalian brains, but the underlying molecular mechanism remains unclear. MicroRNAs (miRNAs) are a class of small noncoding RNAs that modulate gene expression at the post-transcriptional level. However, in specific types of neurocytes, the detailed functions of miRNAs were not entirely understood. We investigated the potential role of miRNAs in astrocyte pathogenesis caused by propofol. We performed genome-wide microRNA expression profiling in immature cultured hippocampal astrocytes by microarray analysis and predicted their targets and functions using bioinformatics tools...
December 2015: Neurotoxicology
https://read.qxmd.com/read/25396122/side-effects-of-topical-steroids-a-long-overdue-revisit
#17
REVIEW
Arijit Coondoo, Meghana Phiske, Shyam Verma, Koushik Lahiri
The introduction of topical steroids (TS) of varying potency have rendered the therapy of inflammatory cutaneous disorders more effective and less time-consuming. However the usefulness of these has become a double edged sword with constantly rising instances of abuse and misuse leading to serious local, systemic and psychological side effects. These side effects occur more with TS of higher potency and on particular areas of the body like face and genitalia. The article reviews the side effects of TS with special mention about peadiatric age group, also includes the measures for preventing the side effects...
October 2014: Indian Dermatology Online Journal
https://read.qxmd.com/read/24715232/kallmann-s-syndrome-and-normosmic-isolated-hypogonadotropic-hypogonadism-two-largely-overlapping-manifestations-of-one-rare-disorder
#18
LETTER
(no author information available yet)
No abstract text is available yet for this article.
May 2014: Journal of Endocrinological Investigation
https://read.qxmd.com/read/24699774/progression-and-prognostic-indicators-of-bronchial-disease-in-children-with-sickle-cell-disease
#19
Sophia N Williams, Eliezer Nussbaum, Leila Yoonessi, Tricia Morphew, Inderpal Randhawa
PURPOSE: The pulmonary complications of sickle cell disease (SCD) are a leading cause of morbidity and mortality (MacLean et al. Am J Respir Crit Care Med 178:1055-1059, 2008; Klings et al. Am J Respir Crit Care Med 173:1264-1269, 2006; National Heart, Lung, and Blood Institute, 2009). Despite this recognition, predictive markers of lung dysfunction progression remain elusive (Klings et al. Am J Respir Crit Care Med 173:1264-1269, 2006; Platt et al. N Engl J Med 330:1639-1644, 1994; Caboot et al...
June 2014: Lung
https://read.qxmd.com/read/24282709/african-experiences-of-humanitarian-cardiovascular-medicine-the-cardiac-centre-of-st-elizabeth-catholic-general-hospital-shisong
#20
Sr Appolonia Budzee, Jc Tantchou Tchoumi, Alessandro Giamberti, Jc Ambassa, Sylvia Cirri, Gianfranco Butera
The cardiac centre of Shisong inaugurated few years ago is a good example of the mobilization of humanitarian resources from the north and south for the improvement of cardiovascular diagnosis and treatment in Africa. From the inauguration of the Center to December 2011, 23 surgical missions have been organized, (5 peadiatric and 18 adults) and 204 patients have been operated with the help of the partners: Associazione Bambini Cardiopatici nel Mondo and Cuore Fratello. The Catheterisation Laboratory has performed a total of 117 diagnostic and interventional procedures while 22 pace makers were implanted (12 single-chambers and 10 dual-chambers)...
June 2012: Cardiovascular Diagnosis and Therapy
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