Megan O Bensignor, Carolyn T Bramante, Eric M Bomberg, Claudia K Fox, Paula M Hale, Aaron S Kelly, Rashmi Mamadi, Nandana Prabhu, Nina M Harder-Lauridsen, Amy C Gross
BACKGROUND: As childhood obesity prevalence increases, determining which patients respond to anti-obesity medications would strengthen personalized approaches to obesity treatment. In the SCALE Teens trial among pubertal adolescents with obesity (NCT02918279), liraglutide 3.0 mg (or maximum tolerated dose) significantly reduced body mass index (BMI) standard deviation score on average versus placebo. That said, liraglutide effects on BMI reduction varied greatly among adolescents, similar to adults...
June 1, 2023: Pediatric Obesity
Geoff D C Ball, Atul K Sharma, Sarah A Moore, Daniel L Metzger, Doug Klein, Katherine M Morrison
To examine the (i) relationships between various body mass index (BMI)-derived metrics for measuring severe obesity (SO) over time based the Centers for Disease Control and Prevention (CDC) and World Health Organization (WHO) references and (ii) ability of these metrics to discriminate children and adolescents based on the presence of cardiometabolic risk factors. In this cohort study completed from 2013 to 2021, we examined data from 3- to 18-year-olds enrolled in the CANadian Pediatric Weight management Registry...
June 2, 2023: European Journal of Pediatrics
Sophie R Kollin, Crystal S Lim, Aaron A Lee
BACKGROUND: Youth with attention-deficit hyperactivity disorder (ADHD) are more vulnerable to developing obesity. Stimulant medication use, an evidence-based treatment for ADHD, is associated with lower body mass index (BMI) and higher blood pressure among non-overweight youth. OBJECTIVES: The purpose of this study was to examine the longitudinal influence of ADHD and stimulant medication use on BMI and blood pressure among a sample of 456 youth with overweight and obesity treated in a paediatric weight management clinic...
June 1, 2023: Pediatric Obesity
Debra E Weese-Mayer, Casey M Rand
No abstract text is available yet for this article.
June 1, 2023: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
Meritxell Rojo-Marticella, Victoria Arija, Paula Morales-Hidalgo, Patricia Esteban-Figuerola, Núria Voltas-Moreso, Josefa Canals-Sans
BACKGROUND: A current area of research interest is the association between ADHD and weight status. This paper aimed to describe the anthropometric status of school children with ADHD, considering age and clinical presentation (inattentive, hyperactive-impulsive, or combined), compared with control children. METHODS: Participants came from the "Epidemiological Research Project on Neurodevelopmental Disorders" and consisted of 198 preschoolers (41 with ADHD) and 389 elementary school children (163 with ADHD)...
May 31, 2023: Pediatric Research
(no author information available yet)
No abstract text is available yet for this article.
May 31, 2023: Pediatric Obesity
Stephanie T Chung, Andrea Krenek, Sheela N Magge
PURPOSE OF REVIEW: The global epidemic of youth-onset obesity is tightly linked to the rising burden of cardiometabolic disease across the lifespan. While the link between childhood obesity and cardiovascular disease is established, this contemporary review summarizes recent and novel advances in this field that elucidate the mechanisms and impact of this public health issue. RECENT FINDINGS: The review highlights the emerging data supporting the relationship between childhood adverse events, social determinants of health, and systemic and institutional systems as etiological factors...
May 31, 2023: Current Atherosclerosis Reports
Nihar Modi, Swapnil Keny, Harshit Dave, Viraj Gandbhir, Shaswat Mishra, Shivaprasad Kolur
INTRODUCTION: Atypical and subacute presentations of pediatric bacterial septic arthritis are difficult to diagnose due to lack of systemic manifestations and inadequate laboratory data. Furthermore, they may mimic certain well-documented pediatric disorders to confound the diagnosis and management. CASE REPORT: The authors present a case of an adolescent obese male with features suggestive of a slipped capital femoral epiphysis (SCFE). Further investigations revealed bacterial septic arthritis which may have contributed to the slip...
May 2023: Journal of Orthopaedic Case Reports
Tatsuhiko Azegami, Keiko Uchida, Yasunori Sato, Ayano Murai-Takeda, Mikako Inokuchi, Hiroshi Itoh, Masaaki Mori
BACKGROUND: Patterns of blood pressure (BP) change from early adolescence to young adulthood have not been well-described. The objective of this study was to examine the predictive value of pediatric BP classification on BP change and identify subpopulations with large BP increases during adolescence and early adulthood. METHODS: Baseline data were obtained from medical checkups of Japanese adolescents aged 12-13 years in 2009 or 2010 and subsequent BP values were followed for a 9-year period...
May 30, 2023: Pediatric Research
David Elkhoury, Christina Elkhoury, Vasavi Rakesh Gorantla
The rise of childhood obesity is a growing concern due to its negative impact on health. Metabolic bariatric surgery (MBS) has gained popularity as an effective and adequate intervention for children and adolescent patients living with severe obesity. Nonetheless, access to MBS for this population is still limited. The objective of this paper is to conduct a comprehensive review of the latest national and international practice guidelines and improve access to MBS for children and adolescents. The paper focuses on the recommendations from the 2023 American Academy of Pediatrics (AAP) and 2022 guidelines from the American Society for Metabolic and Bariatric Surgery (ASMBS) and the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO)...
April 2023: Curēus
Hong-Ying Zhao, Ya-Rong Zhang, Ran Zhang, Yu-Ting Li, Rong-Lian Guo, Wen-Sheng Shi
OBJECTIVE: Central precocious puberty (CPP) is a rare condition that causes early sexual development in children. Although the cure is effective, the etiology of central precocious puberty is unclear. METHODS: In total, 10 girls with central precocious puberty and same number of age-matched female controls were enrolled. Plasma samples were collected from each participant and subjected to untargeted metabolomics and lipidomics. Student's t -tests were employed to compare the mean of each metabolite and lipid...
2023: Frontiers in Pediatrics
Lisa Kakinami, Prince Kevin Danieles, Fatemeh Hosseininasabnajar, Tracie A Barnett, Mélanie Henderson, Andraea Van Hulst, Lisa A Serbin, Dale M Stack, Gilles Paradis
BACKGROUND: The longitudinal relation between parenting practices and styles with children's body mass index z-scores (zBMI) is poorly understood. Previous studies suggest the relationship may be complex, but small samples and short follow-ups diminish the strength of the evidence. The objectives of this study were to investigate whether the relationship is bidirectional, time-varying, and lagged using data from a large, representative birth cohort of Quebec children. METHODS: Data were from the Québec Longitudinal Study of Child Development (QLSCD), a prospective birth cohort (n = 1,602)...
May 29, 2023: BMC Pediatrics
Jamie Zeldman, Ramzi G Salloum, Amy R Mobley
No abstract text is available yet for this article.
May 27, 2023: Journal of the Academy of Nutrition and Dietetics
Irina Gavryutina, Risa Bochner, Vivian Chin, Renee Bargman
Childhood obesity is highly prevalent among certain populations of New York. This cross-sectional pilot study examined the associations between parental attitudes about outdoor activities and body mass index (BMI). A questionnaire was distributed among parents of 1 to 13 aged children at ambulatory pediatric clinics. Of 104 children included in the study 57 were of normal weight and 47 were overweight or obese. Most parents of children with BMI <85% reported frequent playground utilization, considered longer hours to spend outside on weekdays, reported a larger total temperature range for outdoor playground utilization and a lower tolerable minimum temperature compared to parents of children with BMI ≥85%, p < ...
May 29, 2023: Clinical Pediatrics
Agnes G Bucko, Bridget Armstrong, Kerry L McIver, Alexander C McLain, Russell R Pate
BACKGROUND: The limited research assessing relationships between sleep duration and weight status in infants and toddlers relies primarily on parent-reported sleep and cross-sectional studies. OBJECTIVES: Examine whether average sleep duration and changes in sleep duration among 6-24-month-old children were associated with weight-for-length z-scores, and whether these associations varied by race/ethnicity, socioeconomic status and sex. METHODS: Data were collected when children were approximately 6, 12, 18 and 24 months old (N = 116)...
May 28, 2023: Pediatric Obesity
Hua Chen, Ning Lyu, Wenyaw Chan, Austin De La Cruz, Chadi Calarge
OBJECTIVE: The objective was to examine the utilization and predictors of adjuvant metformin among pediatric SGA (mixed receptor antagonist) recipients. METHOD: This study uses 2016 to 2021 data of a national electronic medical record database. Eligible individuals are children aged 6-17 with a new SGA prescription for at least 90 days. Predictors of prescribing adjuvant metformin in general and to non-obese pediatric SGA recipients, in particular, assessed using conditional logistic regression and logistic regression analyses respectively...
May 24, 2023: Journal of the American Academy of Child and Adolescent Psychiatry
Claudia Vales-Villamarín, Olaya de Dios, Iris Pérez-Nadador, Teresa Gavela-Pérez, Leandro Soriano-Guillén, Carmen Garcés
Obesity is associated with the presence of low-grade inflammation even during childhood. The dysregulation in the secretion of adipokines, such as leptin, which occurs in obesity states, could be associated with an increase in inflammatory factors already at an early age. In this cross-sectional study, we aimed to investigate the role of leptin levels in the association between body mass index (BMI) and high-sensitivity C-reactive protein (hs-CRP) in healthy schoolchildren. Leptin and hs-CRP levels were analyzed in two pediatric cohorts comprising 684 prepubertal children and 763 adolescents...
May 19, 2023: Nutrients
Rebekah L Wilson, Jacqueline Soja, Alexandra G Yunker, Hajime Uno, Erin Gordon, Tabitha Cooney, Christina M Dieli-Conwright
Adult survivors of pediatric central nervous system (CNS) tumors are at the highest risk for morbidity and late mortality among all childhood cancers due to a high burden of chronic conditions, and environmental and lifestyle factors. This study aims to epidemiologically characterize young adult survivors of pediatric CNS tumors using body mass index (BMI) to assess risk factors for obesity. Using a cross-sectional design, young adults (18-39 years) previously treated for pediatric CNS tumors and followed in a survivorship clinic during 2016-2021 were examined...
May 11, 2023: Nutrients
Genki Shinoda, Yudai Nagaoka, Fumihiko Ueno, Naoyuki Kurokawa, Ippei Takahashi, Tomomi Onuma, Aoi Noda, Keiko Murakami, Mami Ishikuro, Taku Obara, Hirohito Metoki, Junichi Sugawara, Shinichi Kuriyama
To examine whether body type at birth, body weight, and obesity in early childhood are associated with overweight/obesity during school age and puberty. Data from maternal and child health handbooks, baby health checkup information, and school physical examination information of participants at birth and three-generation cohort studies were linked. Association between body type and body weight at different time intervals (at birth and at 1.5, 3.5, 6, 11, and 14 years of age) were comprehensively analyzed using a multivariate regression model adjusted for gender, maternal age at childbirth, maternal parity, and maternal body mass index, and drinking and smoking statuses at pregnancy confirmation...
May 22, 2023: Children
Marilyn S Townsend, Mical K Shilts, Louise Lanoue, Christiana Drake, L Karina Díaz Rios, Nancy L Keim, Dennis M Styne, Lenna L Ontai
The purpose is to examine validity and reliability for an obesity risk assessment tool developed in Spanish for immigrant families with children, 3-5 years old using an 8-week cross-sectional design with data collected over 1 year at Head Start and Special Supplemental Nutrition Program for Women, Infants and Children [WIC]. Parent/child dyads (206) provided a child obesity risk assessment, three child modified 24 h dietary recalls, three child 36+ h activity logs and one parent food behavior checklist. Main outcome measures were convergent validity with nutrients, cup equivalents, and diet quality and three assessments of reliability that included item difficulty index, item discrimination index, and coefficient of variation...
May 12, 2023: Children
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.