keyword
https://read.qxmd.com/read/38545313/the-role-of-adipokines-and-ghrelin-in-interactions-and-clinical-implications-in-childhood-obesity
#1
JOURNAL ARTICLE
Karrar Haider Haddawi, Ahmed Ghdhban Al-Ziaydi, Fatima Abd Al-Kathem Al-Khalidi
BACKGROUND: Childhood obesity is a growing global health concern, especially prevalent in the Arabian Peninsula, and is known to contribute to metabolic syndrome and insulin resistance. This study aimed to investigate the interplay between adipokines (leptin and adiponectin), ghrelin, and insulin homeostasis in childhood obesity. MATERIAL AND METHODS: A case-control study was conducted in Babylon involving 120 children/adolescents (7-17 years). The participants were divided into two groups: 60 obese and 60 healthy controls...
2024: Journal of Education and Health Promotion
https://read.qxmd.com/read/38542777/exploring-the-role-of-serum-osteonectin-and-hsp27-in-pediatric-mafld-diagnosis-and-cardiometabolic-health
#2
JOURNAL ARTICLE
Anca Bălănescu, Paul-Cristian Bălănescu, Ioana Florentina Codreanu, Iustina-Violeta Stan, Valentina-Daniela Comanici, Alina Maria Robu, Tatiana Ciomârtan
BACKGROUND: Childhood obesity is one of the major challenges of public health policies. The problem of fatty liver in childhood, known as MAFLD (metabolic dysfunction-associated fatty liver disease), is of particular interest as the gold standard diagnosis technique is invasive (liver biopsy). Hence, efforts are made to discover more specific biomarkers for the MAFLD signature. Therefore, the aim of the study was to evaluate Osteonectin and Hsp27 as biomarkers for MAFLD diagnosis and to assess their links with auxological and biochemical profiles of overweight and obese pediatric subjects...
March 16, 2024: Nutrients
https://read.qxmd.com/read/38541645/optimizing-childhood-obesity-management-the-role-of-edmonton-obesity-staging-system-in-personalized-care-pathways
#3
REVIEW
Astrid De Wolf, Elise Nauwynck, Jesse Vanbesien, Willem Staels, Jean De Schepper, Inge Gies
Childhood obesity, affecting 29% of 7-9-year-olds across 33 European countries, is a significant public health challenge. Its persistence into adulthood poses grave health risks influenced by genetic, environmental, and socio-economic factors. Belgium introduced a new care pathway in December 2023, based on the Edmonton Obesity Staging System for Pediatrics (EOSS-P), addressing four health domains and staging obesity severity. This pathway operates across three levels: primary care physicians, Paediatric Multidisciplinary Obesity Management Centres (PMOCs), and Centers of Expertise for Paediatric Obesity Management (CEPOs)...
February 28, 2024: Life
https://read.qxmd.com/read/38541626/the-effect-of-age-hypertension-and-overweight-on-arterial-stiffness-assessed-using-carotid-wall-echo-tracking-in-childhood-and-adolescence
#4
JOURNAL ARTICLE
Tomas Jurko, Michal Mestanik, Eva Jurkova, Kamil Zelenak, Eva Klaskova, Alexander Jurko
Arterial stiffness represents an independent predictor of the risk of subsequent cardiovascular events. Early identification of high-risk individuals is necessary for effective prevention and targeted interventions. Carotid wall echo-tracking is a modern method for an accurate evaluation of the structural and functional properties of carotid arteries. This study aimed to assess age and sex-specific reference values of the echo-tracking parameters of carotid stiffness in 400 healthy children and adolescents and to evaluate the potential early effect of elevated blood pressure and overweight in 69 overweight normotensives, 45 white coat hypertensives, and 44 essential hypertensives...
February 23, 2024: Life
https://read.qxmd.com/read/38539404/association-between-thyroid-function-and-insulin-resistance-indices-in-korean-adolescents-findings-from-the-2014-2015-korea-national-health-and-nutrition-examination-survey
#5
JOURNAL ARTICLE
Eunji Mun, Hye Ah Lee, Jung Eun Choi, Rosie Lee, Kyung Hee Kim, Hyesook Park, Hae Soon Kim
AIM: This study investigated the sex-specific association between thyroid function and various insulin resistance (IR) indices, including noninsulin-based IR indices, in euthyroid adolescents. METHODS: A total of 465 adolescents (aged 12-18 years; 255 boys and 210 girls) based on data from the 2014-2015 Korea National Health and Nutrition Examination Survey were included. Serum thyrotropin (thyroid-stimulating hormone [TSH]) and free thyroxine (fT4) were used to assess thyroid function, whereas the homeostasis model assessment of insulin resistance (HOMA-IR), quantitative insulin-sensitivity check index (QUICKI), glucose/insulin ratio (GIR), triglyceride-glucose (TyG) index, and triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio were used to assess IR...
March 20, 2024: Children
https://read.qxmd.com/read/38539369/alterations-of-nutritional-status-in-children-and-adolescents-with-acute-lymphoblastic-leukemia
#6
JOURNAL ARTICLE
Izabela Kranjčec, Ines Pranjić, Jelena Roganović, Maja Pavlović, Nada Rajačić, Sara Sila
Malnutrition is often observed in pediatric cancer patients and has been recognized as a risk factor for relapse and survival. Maintaining an appropriate nutritional status during anticancer treatment has, therefore, been more and more frequently perceived as an additional requirement for optimal therapy outcomes. The aim of our study was to establish alterations of nutritional status in 26 children and adolescents treated for acute lymphoblastic leukemia (ALL) at the Children's Hospital in Zagreb, Croatia, between 2016 and 2021, by using anthropometric measures and serum albumin levels...
March 11, 2024: Children
https://read.qxmd.com/read/38539349/new-clinical-markers-of-oxidized-lipid-associated-protein-damage-in-children-and-adolescents-with-obesity
#7
JOURNAL ARTICLE
Eirini Kostopoulou, Athina Varemmenou, Electra Kalaitzopoulou, Polyxeni Papadea, Marianna Skipitari, Andrea Paola Rojas Gil, Bessie E Spiliotis, Sotirios Fouzas, Christos D Georgiou
Obesity in children and adolescents has been associated with oxidative stress (OS). The lipid hydroperoxides (LOOH) and the malondialdehyde (MDA) and thiobarbituric reactive substances (TBARS) that oxidatively modify proteins (Pr) (i.e., PrMDA and PrTBARS, respectively) represent markers of OS-associated lipid peroxidation. We aimed to assess OS in children and adolescents with obesity using-for the first time-markers involved in the early and late lipid oxidation process. LOOH, PrMDA, and PrTBARS were investigated in 41 children and adolescents with obesity and 31 controls...
March 6, 2024: Children
https://read.qxmd.com/read/38539322/children-s-health-wellbeing-and-academic-outcomes-over-the-summer-holidays-a-scoping-review
#8
REVIEW
Emily Eglitis, Aaron Miatke, Rosa Virgara, Amanda Machell, Timothy Olds, Mandy Richardson, Carol Maher
BACKGROUND: The school day provides a supportive and stimulating environment that may protect children and adolescents (5-18 years) from behaviours that are adverse for health and wellbeing. OBJECTIVE: To review the literature regarding changes in children's academic achievement or overall wellbeing during the extended school summer break and evaluate if the outcomes are different for children experiencing disadvantage. METHODS: The peer-reviewed literature was searched across six electronic databases for studies tracking changes in any academic, health or wellbeing outcome in children over the summer holidays...
February 27, 2024: Children
https://read.qxmd.com/read/38539310/glucagon-like-peptide-1-receptor-agonists-a-potential-new-medication-for-pediatric-metabolic-dysfunction-associated-steatotic-liver-disease-masld
#9
JOURNAL ARTICLE
Erika Choi, Ana Ramirez Tovar, Zhulin He, Dellys M Soler Rodriguez, Miriam B Vos, Shruthi Arora, Doris Fadoju
Metabolic-dysfunction-associated steatotic liver disease (MASLD) is the most common liver disease in children in the US and, if untreated, may progress to end-stage liver disease. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown improvement in MASLD markers in adults with type 2 diabetes mellitus (T2DM). Currently, there is a lack of medications available for the treatment of pediatric MASLD. We aimed to provide preliminary data on the effects of GLP-1 RAs on markers of MASLD in a retrospective study, in an effort to bridge this gap in the pharmacotherapies available...
February 23, 2024: Children
https://read.qxmd.com/read/38539304/prenatal-alcohol-exposure-and-metabolic-disorders-in-pediatrics-the-role-of-the-oxidative-stress-a-review-of-the-literature
#10
REVIEW
Martina Derme, Martina Briante, Mauro Ceccanti, Giuseppe Giannini, Mario Vitali, Marisa Patrizia Messina, Maria Grazia Piccioni, Alessandro Mattia, Simona Nicotera, Alba Crognale
Prenatal alcohol exposure is responsible for increasing chronic disease risk in later life, including obesity and metabolic syndrome. Alcohol drinking may compromise endogenous antioxidant capacity, causing an increase in free radicals and reactive oxygen species in the newborn. Excessive reactive oxygen species could attack the cellular proteins, lipids, and nucleic acids, leading to cellular dysfunction. Moreover, oxidative stress could play a crucial role in the altered synthesis and release of neurotrophins and progressive mitochondrial modifications with uncontrolled apoptosis...
February 21, 2024: Children
https://read.qxmd.com/read/38536489/infra-areolar-subcutaneous-mastectomy-in-the-surgical-treatment-of-adolescent-gynecomastia
#11
JOURNAL ARTICLE
Özlem Balcı, İbrahim Karaman, Ayşe Karaman
BACKGROUND: Despite being a common condition in puberty, only 5-10% of pubertal gynecomastia need surgical treatment. Here the authors present their experiences with infra-areolar subcutaneous mastectomy in the surgical treatment of adolescent gynecomastia. METHODS: The records of patients who underwent infra-areolar subcutaneous mastectomy for adolescent gynecomastia between January 2004 and December 2021 were reviewed retrospectively. The patients' demographic data, complaints and clinical presentation, physical examination, laboratory and radiological findings, surgical management, and postoperative follow-ups were evaluated...
March 27, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38535908/associations-between-urinary-mercury-cadmium-concentrations-and-anthropometric-features-in-korean-children
#12
JOURNAL ARTICLE
Min Won Shin, Hyo-Bin Kim, Ahreum Kwon, Mi Jung Park, Shin-Hye Kim
Investigating the impact of urinary mercury and cadmium on anthropometric parameters in Korean children is crucial amid growing concerns about heavy metal exposure and childhood growth. Using data from the Korean National Environmental Health Survey (2015-2017), we assessed age- and sex-specific associations of urinary mercury and cadmium with height and body mass index (BMI) z-scores in 1458 children aged 3-5 (n = 571) and 6-11 years (n = 887). Overall, 5.0% had stunted height (3-5 years: 6.9%, 6-11 years: 3...
February 24, 2024: Toxics
https://read.qxmd.com/read/38535131/cardiometabolic-risk-profiles-of-adolescents-living-with-perinatally-acquired-hiv-in-south-africa
#13
JOURNAL ARTICLE
Leonore Greybe, Shaun Barnabas, Mark Cotton, Penelope Rose, Helena Rabie, Lisa Frigati
BACKGROUND: We assessed the Pathological Determinants of Atherosclerosis in Youth (PDAY) score and other potential cardiovascular disease risk factors in adolescents previously enrolled in the Children with HIV Early antiRetroviral (CHER) and International Maternal Pediatric Adolescent AIDS Clinical Trials Network P1060 clinical trials. METHODS: Coronary artery and abdominal aorta (AA) PDAY scores were calculated for 56 participants over 15 years of age using a weighted combination of dyslipidemia, cigarette smoking, hypertension, obesity, and hyperglycemia...
March 26, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38531758/bowel-bladder-dysfunction-in-control-children-in-a-pediatric-urology-office
#14
JOURNAL ARTICLE
Priscilla Rodriguez, Alexandra Rehfuss, Adam Howe, Karla Giramonti, Paul J Feustel, Barry A Kogan
INTRODUCTION: Bowel bladder dysfunction (BBD) is common in children. Risk factors for BBD include age, gender, obesity, and behavioral issues such as ADHD. We investigated the modified Swedish Bowel-Bladder questionnaire as a sensitive indicator of BBD in healthy children. OBJECTIVES: We tested the usefulness of the Swedish Bowel-Bladder Questionnaire (BBQ) as an indicator of BBD in children not complaining of bowel/bladder dysfunction at the time of their visit to a pediatric urologist...
March 15, 2024: Journal of Pediatric Urology
https://read.qxmd.com/read/38527829/mission-impossible-managing-the-american-academy-of-pediatrics-obesity-guideline
#15
JOURNAL ARTICLE
Eleanor R Menzin
A primary care pediatrician casts a skeptical eye at the American Academy of Pediatrics Obesity Guideline. Using back-of-the-envelope calculations, she explains that meeting the guidelines would swamp her office, hospital, and the country's clinicians in a manner that is unrealistic. Warning against the alienation that boots-on-the-ground clinicians experience when guidelines are too theoretical to be practical, she suggests alternative avenues for addressing this public health issue.
2024: Annals of Family Medicine
https://read.qxmd.com/read/38523842/epidemiology-and-distribution-of-cruciate-ligament-injuries-in-children-and-adolescents-with-an-analysis-of-risk-factors-for-concomitant-meniscal-tear
#16
JOURNAL ARTICLE
Xinwang Zhi, Zhicheng Wen, Jiexin Zhang, Dongbo Lai, Huilan Ye, Jianping Wu, Jintao Li, Yan Shao, Federico Canavese, Chun Zeng, Hongwen Xu
INTRODUCTION: To investigate the epidemiological features and prevalence of cruciate ligament injuries (CLI) in children and adolescents, and to examine the potential risk factors associated with concomitant meniscal tear (MT) among this population. METHODS: The demographic data and injury details of children and adolescents with CLI from Southeast China were analyzed to describe their distribution characteristics, alongside an analysis of the prevalence of MTs, the most frequent complication...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38523841/characteristics-of-adolescents-referred-for-bariatric-surgery-in-abu-dhabi-united-arab-emirates
#17
JOURNAL ARTICLE
Reem Hassan Beck, Imrana Afrooz, Muhammad Suhail Masalawala, Rama Watad, Talat Al Shaban, Asma Deeb
About a third of children and adolescents are overweight or obese in the United Arab Emirates, and referrals for metabolic and bariatric surgery (MBS) are now common. Despite excellent evidence that MBS should be considered in adolescents with severe obesity, it remains a management approach of last resort in many cases. Baseline, real-world data on adolescent patients living with obesity referred for surgery, their characteristics, and how these relate to current and future referral policy are important to ensure best practice...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38523835/dietary-habits-depression-and-obesity-an-intricate-relationship-to-explore-in-pediatric-preventive-strategies
#18
REVIEW
Valeria Calcaterra, Virginia Rossi, Vittoria Carlotta Magenes, Paola Baldassarre, Roberta Grazi, Martina Loiodice, Valentina Fabiano, Gianvincenzo Zuccotti
Obesity and depression represent major health problems due to their high prevalence and morbidity rates. Numerous evidences elucidated the connections between dietary habits and the incidence or severity of depression. This overview aims to investigate the intricate relationship between dietary patterns and depression with the objective of elaborating preventive strategies for childhood obesity. Literature data recognized that there is a link between mood and food choices, with certain foods selected for their impact on the brain's reward centers...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38522477/nutritional-status-and-age-at-menarche-in-amazonian-students
#19
JOURNAL ARTICLE
Kettyuscia Coelho E Oliveira, José Cardoso Neto, Davi C Aragon, Sonir R Antonini
OBJECTIVES: Age at menarche (MA) is a proxy for biological maturation and a parameter of socioeconomic changes. Worldwide, anticipation of menarche is associated with nutritional transition and excess weight. The objective of this study was to evaluate the MA in Amazonian students and its association with nutritional status, ethnicity, and socioeconomic level. METHODS: Cross-sectional study with 1,017 students aged 6 to 17 living in the city of Manaus, Brazil. MA was analyzed by status quo and recall; its association with body mass index (BMI), race, socioeconomic status, and adult height was examined...
March 21, 2024: Jornal de Pediatria
https://read.qxmd.com/read/38522210/bored-afraid-alone-what-can-we-learn-from-children-with-paediatric-obesity-about-the-impact-of-the-covid-19-pandemic-for-future-pandemics-care-practices-and-policies
#20
JOURNAL ARTICLE
Siegnella Concincion, Lieke van Houtum, Arnoud Verhoeff, Christine Dedding
PURPOSE: The aim of this study was to gain insight into the perspectives of children with paediatric obesity themselves, during the pandemic and afterwards, regarding their wellbeing and health, and to solicit their advice on tailoring obesity care to match their daily realities. DESIGN AND METHODS: We used a 'draw, write and tell' interview technique, conducted walk-alongs, participant observations and a group session with children with paediatric obesity from seldom-heard communities in Amsterdam, the Netherlands...
March 23, 2024: Journal of Pediatric Nursing
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