Grace Ndeezi, Siobhan M Mor, Luke R Ascolillo, Hannington B Tasimwa, Ritah Nakato, Lilian N Kayondo, Saul Tzipori, David Mukunya, Jeffrey K Griffiths, James K Tumwine
Giardia duodenalis is a common gastrointestinal pathogen globally that has been associated with growth failure in children. Most of the studies have been done in school-age children, and there is a paucity of data in pre-school children. We determined the prevalence and factors associated with G. duodenalis infection in children aged 9-36 months presenting to Mulago Hospital with diarrhea or cough. Demographic and socio-economic characteristics, animal ownership, medical history, and physical examination findings were recorded...
May 30, 2023: American Journal of Tropical Medicine and Hygiene
Ju-Hyeong Park, Jean M Cox-Ganser
Indoor dampness and mold are prevalent, and the exposure has been associated with various illnesses such as the exacerbation of existing asthma, asthma development, current asthma, ever-diagnosed asthma, bronchitis, respiratory infection, allergic rhinitis, dyspnea, wheezing, cough, upper respiratory symptoms, and eczema. However, assessing exposures or environments in damp and moldy buildings/rooms, especially by collecting and analyzing environmental samples for microbial agents, is complicated. Nonetheless, observational assessment (visual and olfactory inspection) has been demonstrated as an effective method for evaluating indoor dampness and mold...
July 2022: Buildings (Basel)
B-J Ling, Y-M Wan
OBJECTIVE: We aim to investigate the treatment efficacy of combinational applications of oral probiotic with intravenous infusion of antibiotics in pediatric bronchopneumonia infection. PATIENTS AND METHODS: A total of 76 pediatric patients with bronchopneumonia infection were included in the study. We divided the patients into observation group (n=38) and control group (n=38). The patients in control group received intravenous infusion of antibiotics and symptomatic treatments...
May 2023: European Review for Medical and Pharmacological Sciences
Fatemeh Sodeifian, Noosha Samieefar, Sepideh Shahkarami, Elham Rayzan, Simin Seyedpour, Meino Rohlfs, Christoph Klein, Delara Babaie, Nima Rezaei
BACKGROUND: Primary ciliary dyskinesia (PCD), also known as the immotile-cilia syndrome, is a clinically and genetically heterogeneous syndrome. Improper function of the cilia causes impaired mucociliary clearance. Neonatal respiratory distress, rhinosinusitis, recurrent chest infections, wet cough, and otitis media are respiratory presentations of this disease. It could also manifest as infertility in males as well as laterality defects in both sexes, such as situs abnormalities (Kartagener syndrome)...
2023: Case Reports in Medicine
Ning Chen, Han Zhang, Yong Feng
BACKGROUND: Protracted bacterial bronchitis (PBB) is often diagnosed clinically according to chronic wet cough, which can be resolved by appropriate antibiotics. Though rarely performed in PBB diagnosis, bacterial cultures by sputum or bronchoalveolar lavage (BAL) fluid can provide etiological features, which may be different in western countries and different areas of China. This study aimed to investigate the clinical and etiological features and outcomes in children of different ages with PBB in northeast China...
2023: Frontiers in Pediatrics
Eleanor Main, Sarah Rand
BACKGROUND: Cystic fibrosis (CF) is an inherited life-limiting disorder. Over time persistent infection and inflammation within the lungs contribute to severe airway damage and loss of respiratory function. Chest physiotherapy, or airway clearance techniques (ACTs), are integral in removing airway secretions and initiated shortly after CF diagnosis. Conventional chest physiotherapy (CCPT) generally requires assistance, while alternative ACTs can be self-administered, facilitating independence and flexibility...
May 5, 2023: Cochrane Database of Systematic Reviews
Nisreen Rumman, Mahmoud R Fassad, Corine Driessens, Patricia Goggin, Nader Abdelrahman, Adel Adwan, Mutaz Albakri, Jagrati Chopra, Regan Doherty, Bishara Fashho, Grace M Freke, Abdallah Hasaballah, Claire L Jackson, Mai A Mohamed, Reda Abu Nema, Mitali P Patel, Reuben J Pengelly, Ahmad Qaaqour, Bruna Rubbo, N Simon Thomas, James Thompson, Woolf T Walker, Gabrielle Wheway, Hannah M Mitchison, Jane S Lucas
BACKGROUND: Diagnostic testing for primary ciliary dyskinesia (PCD) started in 2013 in Palestine. We aimed to describe the diagnostic, genetic and clinical spectrum of the Palestinian PCD population. METHODS: Individuals with symptoms suggestive of PCD were opportunistically considered for diagnostic testing: nasal nitric oxide (nNO) measurement, transmission electron microscopy (TEM) and/or PCD genetic panel or whole-exome testing. Clinical characteristics of those with a positive diagnosis were collected close to testing including forced expiratory volume in 1 s (FEV1 ) Global Lung Index z-scores and body mass index z-scores...
March 2023: ERJ Open Research
Antony Terance Benjamin, Ram Ganesh
No abstract text is available yet for this article.
January 2023: Indian Journal of Medical Research
Antony Terance Benjamin, Ram Ganesh
No abstract text is available yet for this article.
April 3, 2023: Indian Journal of Medical Research
You-Yang Wang, Hong-Wei Fan, Xiao-Ming Huang, Yang Jiao
BACKGROUND: Cupping therapy is a complementary and alternative medical therapy used especially in pain management. It is generally considered a safe procedure, but complications, including life-threatening infection, may still occur. Understanding these complications is essential to safe and evidence-based use of cupping in practice. CASE PRESENTATION: Here we report a rare case of disseminated Staphylococcus aureus infection after cupping therapy. After wet cupping, a 33-year-old immunocompetent woman developed fever, myalgia, and a productive cough accompanied by acute liver and kidney injury, iliopsoas abscess, and gastrointestinal bleeding...
March 30, 2023: BMC complementary medicine and therapies
Wegdan M Abd El Wahab, Mona I Ali, Shimaa S Ibrahim, Yasmen A Mohamed, Doaa A Hamdy
Toxocariasis is an underestimated geohelminthic infection which shows respiratory changes concurrent with larval migration. The purpose of the present study was to detect Toxocara seropositivity in asthmatic and pneumonic children, and in turn to evaluate its association with the children clinical manifestations, laboratory test results, and sociodemographic risk factors. A total of 50 asthmatic, 50 pneumonic children and 50 healthy controls were subjected to stool analysis by direct wet mount and concentration techniques to exclude possible cross reactivity...
March 2023: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
Yongqiang Miao, Xueliang Zhao, Fathalrhman Eisa Addoma Adam, Qingfang Xie, Hang Feng, Jingru Ding, Xindong Bai, Juan Wang, Zengqi Yang
According to the findings of a sheep breeding farm in Shaanxi, China, 2.53% (15/594) of sheep exhibited respiratory (clinical) symptoms such as dyspnoea, nasal discharge, wet cough, fever, and progressive emaciation. Although multi-drug treatment strategies (including ampicillin, tylosin, florfenicol, and ceftiofur) have been attempted to improve clinical outcomes, they have only been met with limited success, with a mortality rate of 40%. Ultimately, Aeromonas veronii ( A. veronii ) was identified as the causative pathogen for respiratory disease...
January 29, 2023: Microorganisms
Hyo-Jung Lim, Derek Ka-Hei Lai, Bryan Pak-Hei So, Calvin Chi-Kong Yip, Daphne Sze Ki Cheung, James Chung-Wai Cheung, Duo Wai-Chi Wong
Dysphagia is one of the most common problems among older adults, which might lead to aspiration pneumonia and eventual death. It calls for a feasible, reliable, and standardized screening or assessment method to prompt rehabilitation measures and mitigate the risks of dysphagia complications. Computer-aided screening using wearable technology could be the solution to the problem but is not clinically applicable because of the heterogeneity of assessment protocols. The aim of this paper is to formulate and unify a swallowing assessment protocol, named the Comprehensive Assessment Protocol for Swallowing (CAPS), by integrating existing protocols and standards...
February 8, 2023: International Journal of Environmental Research and Public Health
Francis J Gilchrist, Mathew Aspey, Robert Bowler, Malcolm Brodlie, Seema Desai, Caroline Harris, Emily Hinton, Hemant Kulkarni, Aviva Ogbolosingha, Ian Sinha, Ivonne Solis-Trapala, Joanne Stock, William D Carroll
BACKGROUND: Protracted bacterial bronchitis (PBB) is an endobronchial infection and a the most common cause of chronic wet cough in young children. It is treated with antibiotics, which can only be targeted if the causative organism is known. As most affected children do not expectorate sputum, lower airway samples can only be obtained by bronchoalveolar lavage (BAL) samples taken during flexible bronchoscopy (FB-BAL). This is invasive and is therefore reserved for children with severe or relapsing cases...
November 2022: BMJ Paediatrics Open
Pamela J Laird, Roz Walker, Gabrielle McCallum, Maree Toombs, Melanie Barwick, Peter Morris, Robyn Aitken, Matthew Cooper, Richard Norman, Bhavini Patel, Gloria Lau, Anne B Chang, André Schultz
BACKGROUND: In children, chronic wet cough may be a sign of underlying lung disease, including protracted bacterial bronchitis (PBB) and bronchiectasis. Chronic (> 4 weeks in duration) wet cough (without indicators pointing to alternative causes) that responds to antibiotic treatment is diagnostic of PBB. Timely recognition and management of PBB can prevent disease progression to irreversible bronchiectasis with lifelong consequences. However, detection and management require timely health-seeking by carers and effective management by clinicians...
December 29, 2022: BMC Pulmonary Medicine
Madison Cohen-McFarlane, Pengcheng Xi, Bruce Wallace, Karim Habashy, Saiful Huq, Rafik Goubran, Frank Knoefel
Goal: The evaluation of respiratory events using audio sensing in an at-home setting can be indicative of worsening health conditions. This paper investigates the use of image-based transfer learning applied to five audio visualizations to evaluate three classification tasks (C1: wet vs. dry vs. whooping cough vs. restricted breathing; C2: wet vs. dry cough; C3: cough vs. restricted breathing). Methods: The five visualizations (linear spectrogram, logarithmic spectrogram, Mel-spectrogram, wavelet scalograms, and aggregate images) are applied to a pre-trained AlexNet image classifier for all tasks...
2022: IEEE open journal of engineering in medicine and biology
Elpiniki Kartsiouni, Stylianos Chatzipanagiotou, Angeliki Galani, Dafni Moriki, Olympia Sardeli, Spyridon Prountzos, Efthymia Alexopoulou, Ioanna Loukou, Kostas N Priftis, Konstantinos Douros
Children with chronic wet cough and without cystic fibrosis (non-CF) may suffer from chronic suppurative lung disease (CSLD) or bronchiectasis. Pseudomonas aeruginosa (Pa) can be one of the offending microbes in these children. The present study aimed to describe the clinical course of children with the above two conditions who were infected with Pa. Data of 54 children with CSLD/bronchiectasis who were diagnosed and attended in our department were retrospectively analysed through a Cox proportional hazard model, with age, presence of bronchiectasis, use of inhaled colistin, azithromycin, inhaled hypertonic saline as the covariates...
November 25, 2022: Children
Guignali Laurette Mangouka, Berthe Amélie Iroungou, Pamela Moussavou-Boundzanga, Jean Raymond Nzenze
BACKGROUND Kidney failure is a public health problem that may require transplantation for patient survival and for those at risk of developing infectious diseases such as COVID-19 due to severe immunosuppression. We report the case of 2 kidney transplant patients who contracted COVID-19. CASE REPORT Patient 1: A 60-year-old Gabonese man presented with 8 days of wet cough, fever, and myalgias associated secondarily with dyspnea, without anosmia or ageusia. His medical history included renal transplant for malignant nephro-angiosclerosis and high blood pressure...
December 22, 2022: American Journal of Case Reports
Yuxia Zhong, Ting Ji, Dan Qin, Deyun Cheng
OBJECTIVE: To analyze clinical characteristics and risk factors for in-hospital mortality in patients coinfected with P. jirovecii and Aspergillus. METHODS: This study included 53 patients with coinfection of P. jirovecii pneumonia (PJP) and invasive pulmonary aspergillosis (IPA) in our center from January 2011 to December 2021. All cases were divided into survivor (n=27) and non-survivor groups (n=26). Medical records, laboratory and radiology data were collected...
September 8, 2022: Journal de Mycologie Médicale
Sandra Gursli, Alexandra Quittner, Reidun Birgitta Jahnsen, Bjørn Skrede, Britt Stuge, Egil Bakkeheim
OBJECTIVE: Airway clearance physiotherapy is recommended in cystic fibrosis, but limited evidence exists to suggest how much treatment is enough. As a secondary analysis of a prior study investigating the safety, efficacy, and participants' perceptions of a novel airway clearance technique, specific cough technique (SCT) compared to forced expiration technique (FET), we aimed to evaluate whether the intervention was associated with changes in health-related quality of life (HRQoL). METHODS: We conducted randomised, controlled individual trials with six adults (N-of-1 RCTs)...
2022: PloS One
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