Yang Zhang, Depeng Wang, Daotong Tan, Anqi Zou, Zhe Wang, Hao Gong, Yu Yang, Lishan Sun, Xiaoliang Lin, Ming Liang, Yi Yu, Xiaoxi He, Guangli Yu, Wei Wang, Chao Cai
Traditional Chinese medicine polysaccharides have numerous biological activities with broad applications in the biomedical industries. However, a clear understanding of the pharmacological activities of compound polysaccharides with multi-component structures remain challenging. This study aimed to investigate the immune boosting effect of compound polysaccharides on the influenza vaccine and assess the preliminary structure-activity relationship. The compound polysaccharide (CP) was isolated from the combined Chinese herbs lentinan, pachymaran and tremellan, and purified by gradient ethanol precipitation to obtain its subcomponents of CP-20, CP-40, CP-60, and CP-80 with decreasing molecular weights...
July 15, 2024: Carbohydrate Polymers