Peter Obid, Karen Yiu, Kenneth Cheung, Kenny Kwan, Michael Ruf, Jason Pui Yin Cheung
INTRODUCTION: Magnetically controlled growing rods (MCGR) for the surgical treatment of early onset scoliosis (EOS) allow non-invasive outpatient based distractions during spinal growth. The purpose of this study is to present the results of a single center case series of 22 patients, evaluate the effect of MCGR treatment on the development of spino-pelvic parameters during growth, and report initial outcomes after end of treatment. MATERIALS AND METHODS: Prospectively collected data of 22 EOS patients with MCGR treatment has been analyzed...
June 18, 2020: Archives of Orthopaedic and Trauma Surgery
Safa C Fassihi, Danny Lee, Andrew A Tran, Ryan Lee, Tom Pollard, Monica Stadecker, Seth Stake, Alice J Hughes, Savyasachi Thakkar
This case describes the challenges associated with total hip arthroplasty in a patient with unique anatomy, including developmental dysplasia of the hip, pelvic dysmorphism, and unilateral sacroiliac joint autofusion. A 30-year-old female, with a history of developmental dysplasia of the hip treated with presumed pelvic osteotomy complicated by postoperative infection, presented with hip pain refractory to conservative management. Radiographic studies demonstrated a 10-cm leg length discrepancy, 20° of acetabular retroversion, severe hemipelvic dysmorphism, ipsilateral sacroiliac joint autofusion, and significant femoral head dysplasia...
March 2020: Arthroplasty Today
Jonathan Bould, William Clegg, Paul G Waddell, Josef Cvačka, Michal Dušek, Michael G S Londesborough
The dimetallic boron hydride cluster, (PMe2 Ph)4 Pt2 B10 H10 ( 1 -Pt2 ), is known to reversibly sequester small molecules (e.g., O2 , CO, and SO2 ) across its Pt-Pt cluster vector. Here, we report the very different effect of the addition of nitric oxide (NO) to solutions of ( 1 -Pt2 ) that prompts the elimination of some of its phosphine ligands and the autofusion of the resultant {(PMe2 Ph) x Pt2 B10 H10 } units to afford the metallaborane conglomerates (PMe2 Ph)8 Pt8 B40 H40 ( 2 -Pt8 , 38%) and (PMe2 Ph)5 Pt4 B20 H20 ( 3 -Pt4 , 34%)...
March 24, 2020: Inorganic Chemistry
Wei Yuan, Ruochen Zhang, Lei Pei, Yue Zhu
BACKGROUND: Grade V thoracic spondylolisthes is secondary to neurofibromatosis type-1(NF-1), especially combined with vertebral fusion, is rare. We reported a case of a 26 year-old female diagnosed with grade V T2spondylolisthesis and T2-T5 autofusion secondary to NF-1, which caused severe kyphotic deformity and neurological deficits, and she was treated with posterior decompression, internal fixation and fusion. CASE DESCRIPTION: A 26 year-old, right-handed female admitted to the clinic due to weakness of her legs...
March 19, 2020: World Neurosurgery
Robert F Murphy, Mark A Pacult, William R Barfield, Richard H Gross, James F Mooney
Limited reports exist with regard to clinical and radiographic details of patients with early-onset spinal deformity (EOSD) undergoing definitive instrumented final fusion (FF) following implantation of a growing construct. Charts and radiographs were queried for all patients who underwent FF after management of EOSD with a distraction-based posterior construct at a single institution from 2006 to 2017. Patients managed during the growth modulation period with either proximal rib or spinal fixation were included...
October 8, 2018: Journal of Pediatric Orthopedics. Part B
Charles Bouthors, Maree T Izatt, Clayton J Adam, Mark J Pearcy, Robert D Labrom, Geoffrey N Askin
BACKGROUND: A new growing rod (GR) design, the semiconstrained growing rod (SCGR), with the added advantage of axial rotation freedom within the components, has been introduced at our center which has been shown to be growth friendly. We hypothesize that the SCGR system would reduce autofusion in vivo, thereby maximizing the coronal plane correction, T1-S1 growth, and the final correction achieved at definitive fusion for children with an early onset scoliosis. METHODS: In total, 28 patients had either single or dual 5...
November 2018: Journal of Pediatric Orthopedics
David Christopher Kieser, Derek Thomas Cawley, Takashi Fujishiro, Simon Mazas, Louis Boissière, Ibrahim Obeid, Vincent Pointillart, Jean-Marc Vital, Olivier Gille
OBJECTIVE The objective of this study was to identify the risk factors of anterior bone loss (ABL) in cervical disc arthroplasty (CDA) and the subsequent effect of this phenomenon. METHODS The authors performed a retrospective radiological review of 185 patients with a minimum 5-year follow-up after CDA (using Bryan, Discocerv, Mobi-C, or Baguera C). Postoperative radiographs were examined and compared to the initial postoperative films to determine the percentage of ABL. The relationship of ABL to potential risk factors was analyzed...
August 2018: Journal of Neurosurgery. Spine
Anna K Hell, Katharina Groenefeld, Konstantinos Tsaknakis, Lena Braunschweig, Heiko M Lorenz
Spine-based fixation of magnetically controlled lengthening devices has been successfully performed for children with early-onset scoliosis. However, spinal manipulation may lead to ossifications, stiffness, and autofusion as previously described. To avoid these problems, a surgical technique combining bilateral externally controlled magnetic device implantation with a rib cradle and pelvic hook fixation was introduced by us in 2011. By using a bilateral single-rib or double-rib cradle fixation and a pelvic hook, the magnetic device is percutaneously inserted...
July 2018: Clinical Spine Surgery
Ingrid Radovanovic, Jennifer C Urquhart, Parham Rasoulinejad, Kevin R Gurr, Fawaz Siddiqi, Christopher S Bailey
OBJECTIVE Previous studies have focused on Type II odontoid fractures and have failed to report on the effect of other C-2 fracture types on treatment and outcome. The purpose of this study was to compare patient characteristics, cause of injury, predisposing factors to fracture, treatments, and mortality rates among C-2 fracture types in a cohort of elderly patients 70 years of age and older. METHODS A retrospective cohort study design was used. Patients who sustained a C-2 fracture between 2002 and 2011 and who were admitted to the authors' Level 1 trauma center were identified using the Discharge Abstract Database and the International Statistical Classification of Diseases and Related Health Problems (ICD-10) code S12...
November 2017: Journal of Neurosurgery. Spine
Idiris Altun, Kasım Zafer Yuksel
STUDY DESIGN: Retrospective review. PURPOSE: We retrospectively reviewed our patients with ankylosing spondylitis (AS) to identify their patterns of spinal fractures to help clarify management strategies and the morbidity and mortality rates associated with this group of patients. OVERVIEW OF LITERATURE: Because of the brittleness of bone and long autofused spinal segments in AS, spinal fractures are common even after minor trauma and often associated with overt instability...
August 2016: Asian Spine Journal
Emilie R C Williamson, Constantine A Demetracopoulos, Scott J Ellis
Few reports in the literature have described the conversion of a surgically fused ankle to a total ankle replacement. The takedown of an autofusion and conversion to a prosthesis has not been described. We report the case of a patient with severe rheumatoid arthritis with an ankle autofusion fixed in equinus and severe talonavicular arthritis that was converted to ankle replacement using the Salto XT revision system. We describe the reasons why the decision was made to perform total ankle arthroplasty while concomitantly fusing the talonavicular joint, and discuss the rationale of the various surgical treatment options considered...
September 2016: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Kee-Yong Ha, Seung-Woo Suh, Young-Hoon Kim, Sang-Il Kim
PURPOSE: The objective of this study is to report the progression of congenital hyperlordoscoliosis in a 2-year-old patient and the use of multiple surgical interventions in the treatment of hyperlordoscoliosis of the thoracic spine. METHODS: A 2-year-old patient with thoracic hyperlordosis underwent observation for 1 year. To halt the progression of hyperlordosis, a posterior laminectomy was carried out to remove all the fused segments. Despite surgery, lordosis progressed via spontaneous autofusion with development of scoliosis with unilateral unsegmented bar...
May 2017: European Spine Journal
Hisham M Awan, Joseph E Imbriglia
Rheumatoid arthritis (RA) can cause severe disability of the hand and fingers. Ankylosis of the finger joints is a known yet underreported manifestation of RA of the hand. We report the case of a patient who had RA and developed autofusion of the proximal interphalangeal (PIP) joints. At presentation, the PIP joints were fused in 15° of flexion. Silicone PIP arthroplasty was performed. Function improved with 60° of PIP joint motion and no pain.
May 2016: American Journal of Orthopedics
Friederike Lattig, Rita Taurman, Anna K Hell
STUDY DESIGN: Case Series. OBJECTIVE: To describe the post-VEPTR (vertical expandable prosthetic titanium rib) treatment changes in early-onset spinal deformity (EOSD), which may influence the final correction spondylodesis. SUMMARY OF BACKGROUND DATA: The VEPTR device, originally developed for the treatment of congenital rib cage malformation, is nowadays more widely used in the treatment of EOSD. At present, only a few reports describe the possible complications that may occur with repeated lengthening procedures of the VEPTR, thereby making the final spondylodesis more complicated and less satisfactory...
June 2016: Clinical Spine Surgery
Paulina Smyda-Dajmund, Jadwiga Śliwka, Iwona Wasilewicz-Flis, Henryka Jakuczun, Ewa Zimnoch-Guzowska
Using DArT analysis, we demonstrated that all Solanum × michoacanum (+) S. tuberosum somatic hybrids contained all parental chromosomes. However, from 13.9 to 29.6 % of the markers from both parents were lost in the hybrids. Somatic hybrids are an interesting material for research of nucleus-cytoplasm interaction and sources of new nuclear and cytoplasmic combinations. Analyses of genomes of somatic hybrids are essential for studies on genome compatibility between species, its evolution and are important for their efficient exploitation...
June 2016: Plant Cell Reports
Najib E El Tecle, Kingsley O Abode-Iyamah, Patrick W Hitchon, Nader S Dahdaleh
Ankylosing spondlylitis is a seronegative spondyloarthropathy that primarily affects the spinal column and sacroiliac joints. With disease progression autofusion of the spinal column takes place. This combined with the brittle bone quality make patients prone to fractures and spinal cord injury. The typical fracture pattern is extension type and involves all three columns. These fractures and injuries may involve the craniovertebral junction, the subaxial cervical spine, and the thoracolumbar spine. While at times these fractures are challenging to manage especially when they affect the elderly, there is evidence that supports long segment fixation and fusion...
December 2015: Clinical Neurology and Neurosurgery
K Song, N Wen, Y Qin, J Kim, H Li, K Snyder, J Gordon, I Chetty, S Siddiqui
PURPOSE: To evaluate the accuracy of a novel open mask for intracranial SRS and to investigate the capability of monitoring intrafraction motion of the patient within this mask using the optical surface monitoring system (OSMS) on a linac-based platform. METHODS: Efficiency was evaluated by measuring mask fabrication time during CT simulation and setup time in the treatment room. Mask shrinkage was assessed by comparing shim settings during treatment to simulation and also by measuring the distance between anterior and posterior sections of the mask on CBCT and Sim CT...
June 2015: Medical Physics
Nauman S Chaudhry, Alp Ozpinar, Wenya Linda Bi, Vamsidhar Chavakula, John H Chi, Ian F Dunn
BACKGROUND: Basilar invagination is a rare clinical condition characterized by upward protrusion of the odontoid process into the intracranial space, leading to bulbomedullary compression. It is often encountered in adults with rheumatoid arthritis. Transoral microscopic or endonasal endoscopic decompression may be pursued, with or without posterior fixation. We present a case of basilar invagination with C1-C2 autofusion and discuss an algorithm for choice of anterior versus posterior approaches...
June 2015: World Neurosurgery
Sanjay S Dhall, Rishi Wadhwa, Michael Y Wang, Alexandra Tien-Smith, Praveen V Mummaneni
OBJECT: Minimally invasive spinal (MIS) surgery techniques have been used sporadically in thoracolumbar junction trauma cases in the past 5 years. A review of the literature on the treatment of thoracolumbar trauma treated with MIS surgery revealed no unifying algorithm to assist with treatment planning. Therefore, the authors formulated a treatment algorithm. METHODS: The authors reviewed the current literature on MIS treatment of thoracolumbar trauma. Based on the literature review, they then created an algorithm for the treatment of thoracolumbar trauma utilizing MIS techniques...
2014: Neurosurgical Focus
P Smyda, H Jakuczun, K Dębski, J Sliwka, R Thieme, M Nachtigall, I Wasilewicz-Flis, E Zimnoch-Guzowska
Phytophthora infestans resistant somatic hybrids of S. × michoacanum (+) S. tuberosum and autofused 4 x S. × michoacanum were obtained. Our material is promising to introgress resistance from S. × michoacanum into cultivated potato background. Solanum × michoacanum (Bitter.) Rydb. (mch) is a wild diploid (2n = 2x = 24) potato species derived from spontaneous cross of S. bulbocastanum and S. pinnatisectum. This hybrid is a 1 EBN (endosperm balance number) species and can cross effectively only with other 1 EBN species...
August 2013: Plant Cell Reports
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