Jason G Mandell, Jennifer Romanowicz, Yue-Hin Loke, Nobuyuki Ikeda, Emily Pena, Umar Siddiqi, Narutoshi Hibino, Mark E Alexander, Andrew J Powell, Laura J Olivieri
AIMS: Coarctation of the aorta is associated with long-term morbidity including decreased exercise capacity, despite successful repair. In the absence of discrete recoarctation, the haemodynamic mechanism remains unknown. This multicentre study evaluated the relationship between aorta shape, flow, and exercise capacity in patients after arch repair, specifically through the lens of aortic size mismatch and descending aortic (DAo) flow and their association with exercise. METHODS AND RESULTS: Cardiac magnetic resonance, cardiopulmonary exercise test, and echocardiogram data within 1 year were analysed from 58 patients (age 28 ± 10 years, 48% male) across four centres with history of isolated arch repair...
January 2024: Eur Heart J Open