Luis Fernández, Marc Matthews, Paul J Kim, Lutfi Barghuthi, Matthew MacEwan, Emily Sallade
INTRODUCTION: Large soft tissue defects resulting from trauma in the pediatric population are common. MLLs are a rare subset of these injuries with no standard treatment regimen. Thorough surgical debridement of these lesions is often warranted to remove necrotic tissue and contamination, which results in a large, open soft tissue defect. STSGs may be used to provide tissue coverage; however, they have limitations, including donor site morbidity and additional surgical time and cost. CASE REPORT: A 12-year-old female with a cutaneous thermal contact burn and an MLL of the right lower medial thigh declined STSG to avoid additional operations...
August 2023: Wounds: a Compendium of Clinical Research and Practice
Sacha C Hauc, Jacqueline M Ihnat, Viola Antonia Stögner, Mica Williams, Jean C Rivera, Helia Hosseini, Lioba Huelsboemer, Michael Alperovich
Pediatric facial burns pose significant challenges in terms of physical, psychological, and social impacts on children. Understanding the causes of these burns is crucial for prevention and appropriate care. This study aims to provide a comprehensive analysis of causes and preventive measures related to pediatric facial burns caused by consumer products. Using data from the National Electronic Injury Surveillance System (NEISS) from 2012 to 2021, we analyzed 130,461 cases of pediatric facial burns. Common causes included household items such as cleaning supplies, hot water, kitchen appliances, and health and beauty products...
August 29, 2023: Journal of Craniofacial Surgery
Jessy Burns, Ryan Phung, Shayna McNeill, Ana Hanlon-Dearman, M Florencia Ricci
Autism spectrum disorder (ASD) is a developmental disorder characterized by deficits in social interaction/communication, restricted interests, and repetitive behaviors. Recent discussions have emerged worldwide regarding the heterogeneity around presentation/etiology and comorbidities. This study aimed to determine the frequency and characteristics of comorbidities among children diagnosed with ASD in Manitoba and to evaluate differences in presentation between those with and without medical comorbidities...
August 19, 2023: Children
Jenny Sun, Don Daniel Ocay, Meghan Halpin, Kimberly Lobo, Dafni F T Frohman, Carolina Donado, Catherine A Brownstein, Casie A Genetti, Anna Madden, Charles B Berde
Erythromelalgia is a descriptive term for severe burning pain and erythema in the distal extremities relieved by cold and exacerbated by heat. Pediatric case series to date are relatively small. We extracted and analyzed medical record data for 42 pediatric patients to describe clinical characteristics, associated conditions, and responses to treatments. Informed consent was obtained according to an IRB-approved protocol that included gene discovery. Three patients had confirmed Nav1.7 sodium channelopathies, with six additional patients under investigation with novel gene candidates...
July 26, 2023: Children
Sabri Karahan, Melike Ayça Ay Kaatsiz, Atiye Erbas, Yunus Kaya
Mothers closely follow the complex process due to the burning of their children. Caring for and supporting the child can pose various challenges for mothers. With the phenomenological method, this study was conducted to investigate mothers' experiences staying with their children in the pediatric burn intensive care unit. Twelve mothers participated in the study. The semi-structured face-to-face interviews obtained data. After each interview, the research team transcribed the interviews verbatim. Interpretive Phenomenological Analysis was used to analyze the data...
August 25, 2023: Journal of Burn Care & Research: Official Publication of the American Burn Association
Vinay Kumar Srivastava, Aman Kumar
Chemical burn of the oral mucosa can occur as a result of the inadvertent, intentional or iatrogenic use of chemicals. Self-treatment for toothache relief with nonpharma ceutical substances can result in a chemical burn. A detailed history is paramount in such cases to identify the etiologic agent to proceed with appropriate treatment. The purpose of this report is to describe the case of an eight-year-old with a complaint of toothache who rinsed his mouth with potassium aluminium sulfate solution to achieve pain relief...
May 15, 2023: Journal of Dentistry for Children
Vanessa L Hull, Yan Wang, Travis Burns, Sarah Sternbach, Shuaishuai Gong, Jennifer McDonough, Fuzheng Guo, Laura N Borodinsky, David Pleasure
Canavan disease (CD) is a recessively inherited pediatric leukodystrophy resulting from inactivating mutations to the oligodendroglial enzyme aspartoacylase (ASPA). ASPA is responsible for hydrolyzing the amino acid derivative N-acetyl-L-aspartate (NAA), and without it, brain NAA concentrations increase by 50% or more. Infants and children with CD present with progressive cognitive and motor delays, cytotoxic edema, astroglial vacuolation, and prominent spongiform brain degeneration. ASPA-deficient CD mice (Aspanur7/nur7 ) present similarly with elevated NAA, widespread astroglial dysfunction, ataxia, and Purkinje cell (PC) dendritic atrophy...
August 23, 2023: Glia
Neta Cohen, Mathew Mathew, Jeffrey Brent, Paul Wax, Adrienne L Davis, Cherie Obilom, Michele M Burns, Joshua Canning, Kevin Baumgartner, Andrew L Koons, Timothy J Wiegand, Bryan Judge, Christopher Hoyte, James A Chenoweth, Blake Froberg, Henry Farrar, Jennifer L Carey, Robert G Hendrickson, Michael Hodgman, E Martin Caravati, Michael R Christian, Brian J Wolk, Steven A Seifert, Yedidia Bentur, Michael Levine, Lynn A Farrugia, David Vearrier, Alicia B Minns, Joseph M Kennedy, Ron I Kirschner, Kim Aldy, Suzanne Schuh, Sharan Campleman, Shao Li, Daniel T Myran, Lisa Feng, Stephen B Freedman, Yaron Finkelstein
INTRODUCTION: An increasing number of jurisdictions have legalized recreational cannabis for adult use. The subsequent availability and marketing of recreational cannabis has led to a parallel increase in rates and severity of pediatric cannabis intoxications. We explored predictors of severe outcomes in pediatric patients who presented to the emergency department with cannabis intoxication. METHODS: In this prospective cohort study, we collected data on all pediatric patients (<18 years) who presented with cannabis intoxication from August 2017 through June 2020 to participating sites in the Toxicology Investigators Consortium...
August 21, 2023: Clinical Toxicology
Niza Alva, Alex R Martínez, Brando Ortiz-Saavedra, Elizbet S Montes-Madariaga, Alonso Cotrina, José A Caballero-Alvarado, Ranjit Sah, Joshuan J Barboza
UNLABELLED: Anti-VEGF drugs like ranibizumab can be used to treat retinopathy of prematurity (ROP) by halting the formation of abnormal blood vessels, or lasers can be used to burn the edges of the retina where these vessels are present. The objective is to compare the efficacy for ROP between ranibizumab and laser therapy. MATERIAL AND METHODS: Electronic searches will be carried out in medical databases with key words and controlled vocabulary terms. Randomized controlled trials (RCT) will be assessed...
2023: Frontiers in Pediatrics
Kristin M Burns
No abstract text is available yet for this article.
August 17, 2023: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Dominic Habgood-Coote, Clare Wilson, Chisato Shimizu, Anouk M Barendregt, Ria Philipsen, Rachel Galassini, Irene Rivero Calle, Lesley Workman, Philipp K A Agyeman, Gerben Ferwerda, Suzanne T Anderson, J Merlijn van den Berg, Marieke Emonts, Enitan D Carrol, Colin G Fink, Ronald de Groot, Martin L Hibberd, John Kanegaye, Mark P Nicol, Stéphane Paulus, Andrew J Pollard, Antonio Salas, Fatou Secka, Luregn J Schlapbach, Adriana H Tremoulet, Michael Walther, Werner Zenz, Michiel Van der Flier, Heather J Zar, Taco Kuijpers, Jane C Burns, Federico Martinón-Torres, Victoria J Wright, Lachlan J M Coin, Aubrey J Cunnington, Jethro A Herberg, Michael Levin, Myrsini Kaforou
BACKGROUND: Appropriate treatment and management of children presenting with fever depend on accurate and timely diagnosis, but current diagnostic tests lack sensitivity and specificity and are frequently too slow to inform initial treatment. As an alternative to pathogen detection, host gene expression signatures in blood have shown promise in discriminating several infectious and inflammatory diseases in a dichotomous manner. However, differential diagnosis requires simultaneous consideration of multiple diseases...
August 11, 2023: Med
Robert J Dabek, Myroslava Decik, Daniel N Driscoll, Gennadiy Fuzaylov
Burn injury accounts for a large proportion of surgically treatable disease. It is estimated that over 180,000 flame burn deaths occur annually across the globe, with roughly 95% occurring in low- or middle-income countries (LMIC). Within these countries children account for a disproportionately high number of burn injuries. As such, the WHO has identified burn prevention as a topic of interest, with an increased need in low- and middle-income countries. Here we describe the creation and implementation of a burn prevention program in Ukraine...
August 19, 2023: Journal of Burn Care & Research: Official Publication of the American Burn Association
Anita A Thomas, Hiromi Yoshida, Ashley E Keilman, Brian Burns, Jessica McDade, Tamar Anderson, Jennifer Reid
When critically ill pediatric patients arrive in the emergency department (ED), a rapid physical evaluation is performed in order to systematically evaluate and address life-threatening conditions. This is commonly referred to as the primary survey. At our institution, pediatric residents are frequently tasked with this role, but they have limited training for or experience with this task. Quality improvement review of real resuscitation recordings at our institution revealed delays in initiation and incomplete primary surveys...
July 2023: Curēus
João Francisco de Castro Silveira, Caroline Brand, Letícia Welser, Anelise Reis Gaya, Ryan Donald Burns, Karin Allor Pfeiffer, Rodrigo Antunes Lima, Lars Bo Andersen, Cézane Priscila Reuter, Hildegard Hedwig Pohl
PURPOSE: Previous literature has demonstrated the mediating role of adiposity in the association between cardiorespiratory fitness (CRF) and cardiometabolic risk as well as the potential role of CRF in attenuating the adverse consequences associated with excess weight. This study aimed to evaluate the mediating role of CRF and adiposity in the possible association with cardiometabolic risk. METHOD: Observational 3-year longitudinal study that included 420 children and adolescents (10...
August 16, 2023: Pediatric Exercise Science
Han Bit Kim, Hyun Noh
OBJECTIVE: To address child abuse effectively requires accurate assessment of the magnitude of the problem. Although it is difficult to assess the scale of child abuse cases nationwide, it can be estimated through the incidence of sentinel injuries, which are defined as minor but unusual injuries such as bruises or wounds in children of precruising age. Therefore, this study aimed to define disease codes for sentinel injuries by age as a preliminary study to elucidate the incidence of sentinel injuries among patients who visited hospitals nationwide...
August 16, 2023: Pediatric Emergency Care
Taima Alrimy, Wadee Alhalabi, Areej Malibari, Fatma Alzahrani, Sharifah Alrajhi, Ayman Yamani, Halah Ahmed, Amro Abduljawad, Essam Nasser, Samar ALattar, Buthinah Alharby, Hasna Khalid, Mohammed Alhalabi, Hunter G Hoffman, Keira P Mason
Although most scald burn injuries involve children under six, because of the challenges of using head mounted displays with young children there is very little research exploring the use of VR in children under six. The current clinical pilot study measured the analgesic effectiveness of our new desktop VR system (with no VR helmet) in children under six during burn wound care (a within-subjects design with randomized treatment order). Between December 2021-April 2022, nine children with burn injuries (10 months to 5 years age, mean = 18 months) participated...
July 28, 2023: Journal of Clinical Medicine
Marcus Hwang, Mark Engelstad, Srinivasa Rama Chandra
Airway injury, Ocular injury and neurovascular tissue damage, burns is all a spectrum of pediatric soft tissue injury complex. Soft tissue injuries to the head and neck area in children are challenging to manage, because these injuries significantly affect the child's overall health and development. Management of such injuries requires a multidisciplinary approach involving surgical and nonsurgical interventions and close collaboration among health care professionals, parents, and caregivers. This article reviews the various causes of injuries, specific considerations for each region of the head and neck, and approaches to the surgical management of soft tissue injuries in pediatric patients, including surgical and adjuvant therapies...
August 9, 2023: Oral and Maxillofacial Surgery Clinics of North America
Emma Larson, Brian Lim Park, Anita Thomas, Daisy Ciener, Julie Augenstein, Suzan Mazor, Rebekah Burns
INTRODUCTION: Jimson weed is a poisonous plant containing tropane alkaloids that can cause anticholinergic toxicity. Recognition of anticholinergic toxidrome is important for prevention and management of potentially life-threatening complications of severe toxicity, including dysrhythmia and seizure. METHODS: Designed for pediatric emergency medicine (PEM) fellows, this simulation featured a 15-year-old female presenting to the emergency department (ED) with agitation and hallucinations...
2023: MedEdPORTAL Publications
Steven W Thornton, Harold J Leraas, Elizabeth Horne, Marcelo Cerullo, Doreen Chang, Emily Greenwald, Suresh Agarwal, Krista L Haines, Elisabeth T Tracy
INTRODUCTION: Most injured children receive trauma care outside of a pediatric trauma center. Differences in physiology, dosing, and injury pattern limit extrapolation of adult trauma principles to pediatrics. We compare US trauma center experience with pediatric and adult trauma resuscitation. MATERIALS AND METHODS: We queried the 2019 Trauma Quality Improvement Program to describe the experience of US trauma centers with pediatric (<15 y) and adult trauma...
August 3, 2023: Journal of Surgical Research
Hünkar Erdoğan, Arzu Sencan
The aim of the study was to reveal the epidemiological characteristics and clinical course of burn patients who were hospitalized in our burn center between 2015-2020 and to compare the results between nationalities. The data were retrospectively evaluated in terms of age, gender, time of admission, the total body surface area burned, the degree of burn, the accident location, the presence of wound infection, surgical intervention, length of hospital stay, mortality, educational status of the parents and nationality...
August 4, 2023: Journal of Burn Care & Research: Official Publication of the American Burn Association
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