Yuna Miyajima, Shigehiro Karashima, Ren Mizoguchi, Masaki Kawakami, Kohei Ogura, Kazuhiro Ogai, Aoi Koshida, Yasuo Ikagawa, Yuta Ami, Qiunan Zhu, Hiromasa Tsujiguchi, Akinori Hara, Shin Kurihara, Hiroshi Arakawa, Hiroyuki Nakamura, Ikumi Tamai, Hidetaka Nambo, Shigefumi Okamoto
Hyperuricemia (HUA) is a symptom of high blood uric acid (UA) levels, which causes disorders such as gout and renal urinary calculus. Prolonged HUA is often associated with hypertension, atherosclerosis, diabetes mellitus, and chronic kidney disease. Studies have shown that gut microbiota (GM) affect these chronic diseases. This study aimed to determine the relationship between HUA and GM. The microbiome of 224 men and 254 women aged 40 years was analyzed through next-generation sequencing and machine learning...
April 30, 2024: Scientific Reports