Akshay Vivek Nandavar, Talya Toledano, Catalina Marino, Shefali Khanna, Yekaterina Sitnitskaya
Objective . To evaluate the burden of Contiguous Osteomyelitis (COM) in pediatric patients with cellulitis/abscess of hands/feet. Methods . Children aged 0-18 years, treated from 2009 to 2019 for cellulitis/abscess of hands/feet, who either had Magnetic Resonance Imaging at presentation, or Roentgenogram >10 days after symptom-onset, were included. Two-tailed T-test was used to compare patients with and without COM. P -value < .05 deemed statistically significant. Results . Twenty of forty-one patients with abscess/cellulitis of distal extremities were diagnosed with COM...
2021: Global Pediatric Health
Ali A Siddiqui, Lindsay M Andras, Kenneth D Illingworth, David L Skaggs
BACKGROUND: There is no evidence-based consensus on the risk factors for concomitant osteomyelitis and septic arthritis. The purpose of this study was to investigate clinical parameters predictive of concomitant osteomyelitis in children with septic arthritis. METHODS: A retrospective review was conducted on patients with septic arthritis with magnetic resonance imaging (MRI) between January 2004 and October 2016 at a tertiary care pediatric hospital. Medical charts were reviewed for information including symptoms, diagnosis of osteomyelitis, serum laboratory studies, joint fluid analyses, imaging results, and treatment...
February 9, 2021: Journal of Pediatric Orthopedics
Lichun Xie, Qingling Long, Guichi Zhou, Sixi Liu, Fei-Qiu Wen
BACKGROUND: Invasive fungal infection (IFI) is one of the most challenging complications in children undergoing acute lymphoblastic leukaemia (ALL) treatment, but acute fungal osteomyelitis (OM) is rarely encountered. CASE PRESENTATION: Here, we describe a case of Candida tropicalis osteomyelitis in a 10-year-old patient with Philadelphia chromosome (Ph)-positive ALL. He was on remission induction therapy at the time of neutropenia, and an abscess developed in his right arm...
February 11, 2021: Italian Journal of Pediatrics
Teresa Giani, Veronica Matteoni, Anna Perrone, Gabriele Simonini, Rolando Cimaz
BACKGROUND: Whole Body Magnetic Resonance Imaging (WBMRI) is a multiregional imaging technique suitable to investigate the extent of multisystemic diseases without exposure to radiation, with a high sensitivity to bone alterations. The aim of our study was to evaluate the role of WBMRI in the workup of children with non-specific musculoskeletal features, and non-indicative laboratory and instrumental data, suspected to have a rheumatologic disease. METHODS: We retrospectively analysed medical records, including laboratory tests and radiological data of 34 children who have been evaluated due to non-specific musculoskeletal manifestations, for which a WBMRI was prescribed...
February 10, 2021: Pediatrics International: Official Journal of the Japan Pediatric Society
Usman Tauseef, Misbah Anjum, Mohsina Ibrahim, Hina Sabih Baqai, Abubakar Tauseef, Marium Tauseef, Muhammad Sohaib Asghar, Maryam Zafar, Uzma Rasheed, Nimra Shaikh
OBJECTIVE: To describe two cases of unusual variants of sickle cell disease. CASE DESCRIPTION: We present two cases of sickle cell disease variants (haemoglobinopathies), from unrelated families, in the state of Balochistan (Pakistan). One was diagnosed with sickle cell disease in the haemoglobin electrophoresis, whereas the other was diagnosed with sickle cell SE disease. Both were diagnosed based on the presentation of osteomyelitis. COMMENTS: Haemoglobin SD disease (Hb SD) and haemoglobin SE disease (Hb SE) are rare haemoglobinopathies in the world...
2021: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Nelson Muñoz, Sandra Galvis, Oscar Patiño, Carlos Moneriz
OBJECTIVE: To report the case of an infant with infrequent cranial osteomyelitis as a complication of furuncular myiasis. CASE DESCRIPTION: The patient was a 4-month-old male who presented to the emergency department with a nodular skull lesion with edema, tenderness, pain, and purulent drainage, as well as progress of the ulcerated lesion and evidence of larvae inside. Antibiotic treatment was initiated, and the patient was taken to the operating room to remove the larvae, but he had no symptomatic improvement...
2021: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Kathryn S Cain, Avinash K Shetty, Lindsay Strowd, Omar Sangueza, Nicholas M Potisek
A previously healthy 15-year-old boy from a rural county in the southeastern United States was evaluated in the emergency department with fever and worsening toe pain in the absence of trauma. He initially presented to his primary care physician 4 weeks before with upper respiratory symptoms and was treated with corticosteroids for presumed reactive airway disease. His respiratory symptoms resolved. One week after this presentation, he developed fever and right great toe pain and presented to an outside hospital...
February 9, 2021: Pediatrics
Christopher J Loftus, Jennifer Ahn, Judith C Hagedorn, Mark Cain, Sarah Holt, Paul Merguerian, Margarett Shnorhavorian
INTRODUCTION: Under the Affordable Care Act, the Dependent Care Provision (DCP) was enacted in 2010 and expanded healthcare coverage for millions of young adults ages 19-25 by allowing them to stay on their parents' insurance until age 26. It is unknown whether the DCP has impacted young adults with SB who are at risk for lapses in insurance coverage as they transition into adult care. OBJECTIVE: Our aim was to determine the impact of the DCP on access to care (insurance status) and healthcare-quality (hospital admissions for potentially preventable conditions)...
January 22, 2021: Journal of Pediatric Urology
Fatma Alzahrani, Anas M Fallatah, Fatimah M Al-Haddad, Shahad T Khayyat, Wasayf M AlMehmadi, Bashaier G AlQahtani, Rawabi S Alamri
Background and objective Sickle cell anemia (SCA) is one of the common genetic diseases in the Kingdom of Saudi Arabia (KSA). This disease results from a genetic mutation that causes malformation of the red blood cells (RBCs), leading to various systemic complications, including vaso-occlusive crisis (VOC), acute chest syndrome (ACS), osteomyelitis, avascular necrosis (AVN), and stroke, to name a few. The leading cause of mortality in SCA is these systemic complications rather than the disease itself. Understanding the risk factors of these complications can help reduce mortality in these patients and improve their quality of life...
January 3, 2021: Curēus
Mónica E Martínez, Jessica Benítez, Lorena B Leguizamón, Oscar H López, Sandra L Grenón, Marta E Mollerach, Martha H von Specht
Streptococcus pneumoniae is a rare cause of osteoarticular infections. We describe 5documented cases that occurred in 2005, 2009, 2011, 2015 and 2017 in patients admitted to the Pediatric Provincial Reference Hospital of Misiones. These cases corresponded to a 4-year-old boy and 4 girls aged 11, 10, 6 years and 4 months with a diagnosis of osteomyelitis of the scapula and humerus, arthritis of the hip, ankle and osteomyelitis of the distal fibula. All of them were in good general condition on admission and one of them was seropositive for human immunodeficiency virus...
February 1, 2021: Revista Argentina de Microbiología
Chan Jing Er, Wong Kin Chun, Lim Ming Chiang, Mohd Naim Bin Mohd Nasir
Osteomyelits due to concurrent multi-drug resistance organisms is difficult to treat for any surgeon and infectious disease physician. An eleven-year-old boy presenting with an open fracture of the left radius and ulna after a fall in a stagnant wet field. Despite prophylactic antibiotics and surgical intervention, the open wound was infected, and Chromobacterium violaceum as well as Klebsiella pneumoniae were isolated. He was treated with six weeks of parenteral cefepime and amikacin and was discharged upon clinical improvement...
2021: Revista do Instituto de Medicina Tropical de São Paulo
Jillian M Cotter, Matt Hall, Sonya Tang Girdwood, John R Stephens, Jessica L Markham, James C Gay, Samir S Shah
BACKGROUND/OBJECTIVE: Pediatric patients hospitalized with bacterial infections often receive intravenous (IV) antibiotics. Early transition to enteral antibiotics can reduce hospital duration, cost, and complications. We aimed to identify opportunities to transition from IV to enteral antibiotics, describe variation of transition among hospitals, and evaluate feasibility of novel stewardship metrics. METHODS: This multisite retrospective cohort study used the Pediatric Health Information System to identify pediatric patients hospitalized with pneumonia, neck infection, orbital infection, urinary tract infection (UTI), osteomyelitis, septic arthritis, or skin and soft tissue infection (SSTI) between 2017 and 2018...
January 20, 2021: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Laura Montserrat Pérez-López, Teresa Subirá-Álvarez, Amalia Martínez-Ruíz, Antoni Noguera-Julian, David Moreno-Romo, Ferran Torner-Rubies, César Galo Fontecha
INTRODUCTION AND OBJECTIVES: Osteoarticular tuberculosis, caused by a member of the Mycobacterium genus, represents approximately 10% of the total extrapulmonary tuberculosis in pediatric patients. Its low prevalence and nonspecific clinical presentation lead to a late diagnosis and elevated risk of sequelae. PATIENTS AND METHODS: This retrospective study included seven pediatric patients with non-vertebral osteoarticular tuberculosis diagnosed between 2006 and 2019...
January 22, 2021: Revista Española de Cirugía Ortopédica y Traumatología
Ehab S Saleh
Intramuscular myxoma is a rare benign tumor that presents as a slow-growing, deeply seated mass confined within a skeletal muscle. Histologically, these lesions most resemble umbilical cord tissue. They mostly occur in people between 40 and 70 years old, with a 57% female predilection. These tumors are very rare in children. Only one pediatric intramuscular myxoma case is reported in the literature. The goal of this study is to report the case of a 13-year-old girl who presented to our hospital emergency department in 2018 with right hip pain, elevated inflammatory markers, and fever; her initial differential diagnosis was hip septic arthritis, pelvic osteomyelitis, and pelvic abscess...
January 19, 2021: Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews
Khalfan Al Abdali, Brendan McMullan, Sara Toofanian, Neevika Manoharan, Pamela Palasanthiran
No abstract text is available yet for this article.
January 19, 2021: Journal of Paediatrics and Child Health
Dermot Mallon, David Doig, Luke Dixon, Anastasia Gontsarova, Wajanat Jan, Francesca Tona
Sickle cell disease is the most common hereditary hemoglobinopathy, which results in abnormally shaped and rigid red blood cells. These sickle-shaped red blood cells cause vaso-occlusion and ischemic phenomena that can affect any organ in the body. As a common cause of disability, the neurological manifestations of sickle cell disease are particularly important. Neuroimaging has a crucial role in the diagnosis, management, and prevention of the complications of sickle cell disease. These complications can affect the brain parenchyma, vasculature, and skull and can be ascribed directly or indirectly to a vasculopathy of small and large vessels...
November 2020: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
Charlie D Wilson, Joshua Lee, Ronak Desai, Russell A Ward
A 14-year-old previously healthy girl presented with atraumatic onset of low back and flank pain and mildly elevated inflammatory markers. Magnetic resonance imaging disclosed an L5 superior endplate fracture, and cultures grew methicillin-susceptible S taphylococcus aureus . We discuss the variable presentations and appropriate treatments of adolescent vertebral osteomyelitis.
October 16, 2020: Proceedings of the Baylor University Medical Center
Nathalia Velasquez, William Strober, Amber Shaffer, Amanda Stapleton
INTRODUCTION: Frontal sinusitis in the pediatric population is a disease that has not been thoroughly studied or characterized. The goals of this study are to characterize the clinical presentation, radiologic variables, treatment modalities, complications, and prognosis associated with acute and chronic frontal sinus disease in the pediatric population. METHODS: IRB-approved retrospective cohort study of pediatric patients who were diagnosed with acute (AFS) or chronic frontal sinusitis (CFS) and underwent frontal sinus surgery at a tertiary level Children's Hospital from 2006 to 2016...
January 13, 2021: Annals of Otology, Rhinology, and Laryngology
Omar A Karadaghy, Jacob C Lucas, Shahnawaz Paroya, Daniel Jensen
This case report describes a child who developed Pott's puffy tumor and was treated at the Children's Mercy Hospital in Kansas City. In addition to a discussion of a case, a review of the literature was completed on this topic describing the typical embryology and development of the frontal sinus, and the epidemiology, diagnosis, and treatment of Pott's puffy tumor. The patient was a 23-month-old boy who developed Pott's puffy tumor after recovery from influenza. The patient presented to the hospital with progressing edema of the unilateral eye that spread bilaterally within a few days...
January 6, 2021: Auris, Nasus, Larynx
Gabrielle Z Hester, Amanda J Nickel, David Watson, Gloria Swanson, Jennifer C Laine, Kelly R Bergmann
BACKGROUND: Pediatric musculoskeletal infection (MSKI) is a common cause of hospitalization with associated morbidity. To improve the care of pediatric MSKI, our objectives were to achieve 3 specific aims within 24 months of our quality improvement (QI) interventions: (1) 50% reduction in peripherally inserted central catheter (PICC) use, (2) 25% reduction in sedations per patient, and (3) 50% reduction in empirical vancomycin administration. METHODS: We implemented 4 prospective QI interventions at our tertiary children's hospital: (1) provider education, (2) centralization of admission location, (3) coordination of radiology-orthopedic communication, and (4) implementation of an MSKI infection algorithm and order set...
January 7, 2021: Pediatrics
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