Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#381
JOURNAL ARTICLE
Fumihiro Yoshimura, Kenichiro Doi, Koichi Kinoshita, Hajime Seo, Taiki Matsunaga, Takuaki Yamamoto
Coronavirus disease 2019 is known to cause severe acute respiratory syndrome, and serious cases need to be treated with corticosteroids. Herein, we report an 87-year-old woman who developed bilateral osteonecrosis of the femoral head after corticosteroid treatment for coronavirus disease 2019-related pneumonia. Sixteen months after treatment, she developed right hip pain without any evidence of trauma. A diagnosis of bilateral osteonecrosis of the femoral head was made based on sclerotic bands on plain radiographs and low-signal bands on T1-weighted magnetic resonance images...
April 8, 2024: Skeletal Radiology
#382
JOURNAL ARTICLE
Felicity Liew, Claudia Efstathiou, Sara Fontanella, Matthew Richardson, Ruth Saunders, Dawid Swieboda, Jasmin K Sidhu, Stephanie Ascough, Shona C Moore, Noura Mohamed, Jose Nunag, Clara King, Olivia C Leavy, Omer Elneima, Hamish J C McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Victoria C Harris, Linzy Houchen-Wolloff, Neil J Greening, Nazir I Lone, Matthew Thorpe, A A Roger Thompson, Sarah L Rowland-Jones, Annemarie B Docherty, James D Chalmers, Ling-Pei Ho, Alexander Horsley, Betty Raman, Krisnah Poinasamy, Michael Marks, Onn Min Kon, Luke S Howard, Daniel G Wootton, Jennifer K Quint, Thushan I de Silva, Antonia Ho, Christopher Chiu, Ewen M Harrison, William Greenhalf, J Kenneth Baillie, Malcolm G Semple, Lance Turtle, Rachael A Evans, Louise V Wain, Christopher Brightling, Ryan S Thwaites, Peter J M Openshaw
One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged symptoms termed long coronavirus disease (COVID), yet disease phenotypes and mechanisms are poorly understood1 . Here we profiled 368 plasma proteins in 657 participants ≥3 months following hospitalization. Of these, 426 had at least one long COVID symptom and 233 had fully recovered. Elevated markers of myeloid inflammation and complement activation were associated with long COVID. IL-1R2, MATN2 and COLEC12 were associated with cardiorespiratory symptoms, fatigue and anxiety/depression; MATN2, CSF3 and C1QA were elevated in gastrointestinal symptoms and C1QA was elevated in cognitive impairment...
April 2024: Nature Immunology
#383
JOURNAL ARTICLE
Zijian Li, Li Zhai, Qinghua Zhang, Wei Zhai, Pai Li, Bo Chen, Changsheng Chen, Yao Yao, Yiyao Ge, Hua Yang, Panzhe Qiao, Jianing Kang, Zhenyu Shi, An Zhang, Hongyi Wang, Jinzhe Liang, Jiawei Liu, Zhiqiang Guan, Lingwen Liao, Vlad Andrei Neacșu, Chen Ma, Ye Chen, Ye Zhu, Chun-Sing Lee, Lu Ma, Yonghua Du, Lin Gu, Jian-Feng Li, Zhong-Qun Tian, Feng Ding, Hua Zhang
Unconventional 1T'-phase transition metal dichalcogenides (TMDs) have aroused tremendous research interest due to their unique phase-dependent physicochemical properties and applications. However, due to the metastable nature of 1T'-TMDs, the controlled synthesis of 1T'-TMD monolayers (MLs) with high phase purity and stability still remains a challenge. Here we report that 4H-Au nanowires (NWs), when used as templates, can induce the quasi-epitaxial growth of high-phase-purity and stable 1T'-TMD MLs, including WS2 , WSe2 , MoS2 and MoSe2 , via a facile and rapid wet-chemical method...
April 8, 2024: Nature Materials
#384
JOURNAL ARTICLE
Suhail Saleem, Muhammad Rafiq, Nauman Ahmed, Muhammad Shoaib Arif, Ali Raza, Zafar Iqbal, Shafiullah Niazai, Ilyas Khan
Most of the countries in the world are affected by the coronavirus epidemic that put people in danger, with many infected cases and deaths. The crowding factor plays a significant role in the transmission of coronavirus disease. On the other hand, the vaccines of the covid-19 played a decisive role in the control of coronavirus infection. In this paper, a fractional order epidemic model (SIVR) of coronavirus disease is proposed by considering the effects of crowding and vaccination because the transmission of this infection is highly influenced by these two factors...
April 8, 2024: Scientific Reports
#385
JOURNAL ARTICLE
Alan Chang, Yung-Ming Jeng, Cheng-Maw Ho, Po-Huang Lee
The coronavirus disease 2019 (COVID-19) pandemic has caused significant morbidity and mortality. Spike messenger RNA (mRNA)-based vaccines against severe acute respiratory syndrome coronavirus 2 may contribute to immune-mediated injuries. Here we present a case of a previously healthy 47-year-old man, who developed progressive jaundice 2 weeks after receiving his 3rd COVID-19 vaccination (1st mRNA-based vaccine). Apart from elevated serum total bilirubin levels (peaked at >70 mg/dL), deteriorating renal (blood urea nitrogen: peak, 108...
April 8, 2024: NPJ Vaccines
#386
JOURNAL ARTICLE
Vikas Manchanda, Oves Siddiqui, Kavita Meena, Anju Sharma, Sonal Saxena
PURPOSE: Indian Council of Medical Research (ICMR) initiated an Inter-Laboratory Quality Control testing (ILQC) program for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) testing. Under this program, SARS CoV-2 testing laboratories across the country submit specimens to the assigned State Quality Control (SQCs) laboratories for ILQC testing. This study aimed to investigate the performance of public and private SARS CoV-2 testing laboratories in Delhi and highlights the country's effort in ramping up testing facility with close monitoring of the quality of Covid-19 testing results...
April 6, 2024: Indian Journal of Medical Microbiology
#387
JOURNAL ARTICLE
Yusuke Okubo, Yosuke Nakabayashi, Kenta Ito, Kazuhiro Uda, Isao Miyairi
BACKGROUND: The COVID-19 pandemic posed substantial challenges to healthcare systems. Understanding the responses of pediatric health services is crucial for future pandemic planning and preparedness, yet such data remains limited. METHODS: In this retrospective cohort study, we analyzed data from administrative databases developed by Japan Medical Data Center and DeSC Healthcare Inc. The dataset comprised records of 2,612,511 children, totaling 60,224,888 person-months, from January 2020 to May 2022...
April 6, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
#388
JOURNAL ARTICLE
Alicia M Schowe, Malvika Godara, Darina Czamara, Mazda Adli, Tania Singer, Elisabeth B Binder
The coronavirus disease 2019 (COVID-19) pandemic was accompanied by an increase in mental health challenges including depression, stress, loneliness, and anxiety. Common genetic variants can contribute to the risk for psychiatric disorders and may present a risk factor in times of crises. However, it is unclear to what extent polygenic risk played a role in the mental health response to the COVID-19 pandemic. In this study, we investigate whether polygenic scores (PGSs) for mental health-related traits can distinguish between four resilience-vulnerability trajectories identified during the COVID-19 pandemic and associated lockdowns in 2020/21...
April 8, 2024: European Archives of Psychiatry and Clinical Neuroscience
#389
JOURNAL ARTICLE
Luis Corral-Gudino, María Piedad Del-Amo-Merino, Jésica Abadía-Otero, Irene Merino-Velasco, Yolanda Lorenzo-Fernández, Jesús García-Cruces-Méndez, José María Eiros-Bouza, Marta Domínguez-Gil González
BACKGROUND: The incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV‑2) infection was highest among older adults early in the COVID-19 pandemic; however, this pattern was later reversed with young adults showing the highest incidence. The aim of this study was to identify risk factors in healthcare workers (HCWs) associated with this evolution. METHODS: We conducted a survey nested within a prospective cohort study of 680 HCWs from a tertiary referral public hospital who received 2 doses of SARS-CoV‑2 vaccine in January and February 2021 (VACCICO-VAO cohort)...
April 8, 2024: Wiener Klinische Wochenschrift
#390
JOURNAL ARTICLE
Meng Li, Yali Hou, Yuzheng Zhou, Zhenni Yang, Hongyu Zhao, Tao Jian, Qianxi Yu, Fuxing Zeng, Xiaotian Liu, Zheng Zhang, Yan G Zhao
β-Coronaviruses remodel host endomembranes to form double-membrane vesicles (DMVs) as replication organelles (ROs) that provide a shielded microenvironment for viral RNA synthesis in infected cells. DMVs are clustered, but the molecular underpinnings and pathophysiological functions remain unknown. Here, we reveal that host fragile X-related (FXR) family proteins (FXR1/FXR2/FMR1) are required for DMV clustering induced by expression of viral non-structural proteins (Nsps) Nsp3 and Nsp4. Depleting FXRs results in DMV dispersion in the cytoplasm...
June 3, 2024: Journal of Cell Biology
#391
JOURNAL ARTICLE
Najing Cao, Yanxing Cai, Xin Huang, Hanxiao Jiang, Ziqi Huang, Lixiao Xing, Lu Lu, Shibo Jiang, Wei Xu
Outbreaks of acute respiratory viral diseases, such as influenza and COVID-19 caused by influenza A virus (IAV) and SARS-CoV-2, pose a serious threat to global public health, economic security, and social stability. This calls for the development of broad-spectrum antivirals to prevent or treat infection or co-infection of IAV and SARS-CoV-2. Hemagglutinin (HA) on IAV and spike (S) protein on SARS-CoV-2, which contain various types of glycans, play crucial roles in mediating viral entry into host cells. Therefore, they are key targets for the development of carbohydrate-binding protein-based antivirals...
April 9, 2024: MBio
#392
JOURNAL ARTICLE
Harvey W Kaufman, Justin K Niles, Ryan C L Brewster, Keith Acosta, Shalini H Shah, Marissa Hauptman
The study objective was to evaluate the impact of the coronavirus disease (COVID-19) pandemic on pediatric blood lead testing in the United States. Clinical laboratory pediatric (ages <6 years) blood lead level (BLL) tests performed by Quest Diagnostics, January 2019-March 2022, were analyzed. Patients were categorized by age, by sex, and, through matching by ZIP code with US Census data, for race, ethnicity, pre-1950 housing, and poverty estimates. Over 2.8 million results from children (<6 years old) from all 50 states and the District of Columbia were included...
April 8, 2024: Population Health Management
#393
JOURNAL ARTICLE
Franco Sviercz, Patricio Jarmoluk, Joshua Godoy Coto, Cintia Cevallos, Rosa Nicole Freiberger, Cinthya Alicia Marcela López, Irene Lucia Ennis, M Victoria Delpino, Jorge Quarleri
The Coronavirus Disease 2019 (COVID-19) pandemic has resulted in the loss of millions of lives, although a majority of those infected have managed to survive. Consequently, a set of outcomes, identified as long COVID, is now emerging. While the primary target of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the respiratory system, the impact of COVID-19 extends to various body parts, including the bone. This study aims to investigate the effects of acute SARS-CoV-2 infection on osteoclastogenesis, utilizing both ancestral and Omicron viral strains...
April 2024: Journal of Medical Virology
#394
JOURNAL ARTICLE
Pallavi Rai, Jeffrey M Marano, Lin Kang, Sheryl Coutermarsh-Ott, Andrea R Daamen, Peter E Lipsky, James Weger-Lucarelli
Obesity has been identified as an independent risk factor for severe outcomes in humans with coronavirus disease 2019 (COVID-19) and other infectious diseases. Here, we established a mouse model of COVID-19 using the murine betacoronavirus, mouse hepatitis virus 1 (MHV-1). C57BL/6 and C3H/HeJ mice exposed to MHV-1 developed mild and severe disease, respectively. Obese C57BL/6 mice developed clinical manifestations similar to those of lean controls. In contrast, all obese C3H/HeJ mice succumbed by 8 days postinfection, compared to a 50% mortality rate in lean controls...
April 2024: Journal of Medical Virology
#395
JOURNAL ARTICLE
Phiman Thirarattanasunthon, Phuwasin Buakate, Paleeratana Wongrith, Kaemkan Kaewjamrat, Preeyaphat Phatboot, Pattamaporn Srithongpeng
BACKGROUND: The global impact of the Coronavirus Disease 2019 (COVID-19) pandemic has been enormous. The primary school's role and responsibilities include providing students with education and training, cooperating and supporting educational management, and monitoring, following up, and evaluating the school's operations. OBJECTIVE: The goals of this study were to evaluate the conditions of preparation for the COVID-19 epidemic's prevention and response, as well as to investigate the relationship between predisposing, enabling, and reinforcing factors in preventing the spread of COVID-19 among primary school students in the educational area...
2024: Roczniki Państwowego Zakładu Higieny
#396
JOURNAL ARTICLE
M V Fedulova
OBJECTIVE: To determine morphological alterations in lung tissues in the case of novel coronavirus infection (COVID-19) in the aspect of process staging with consideration to disease duration. MATERIAL AND METHODS: The number of COVID-19-related deaths of patients aged 55-65 years equal 17 were investigated. Serial cuts of lung tissue stained with hematoxylin and eosin, obtained from several lung fragments of each corpse, were analyzed. Morphological features previously described in literature sources were taken into account...
2024: Sudebno-meditsinskaia Ekspertiza
#397
JOURNAL ARTICLE
Joanna Frąckiewicz, Zuzanna Tarwacka, Małgorzata Ewa Drywień
BACKGROUND: Due to the spread of COVID-19 infections around the world, in early 2020, the World Health Organization (WHO) announced a global pandemic, i.e. an epidemic of particularly large dimensions affecting countries and entire continents. Long-term stay at home and self-isolation may have significantly impacted lifestyle, diet, food choices and access to food, as well as physical activity in the entire population, including students. OBJECTIVE: The aim of the study was to examine the impact of social isolation caused by the coronavirus pandemic on changes in diet, lifestyle and body mass index in a group of students, so that we would be better prepared for future new viral infections with characteristics similar to Covid-19...
2024: Roczniki Państwowego Zakładu Higieny
#398
JOURNAL ARTICLE
Francesco Inchingolo, Angelo Michele Inchingolo, Fabio Piras, Laura Ferrante, Antonio Mancini, Andrea Palermo, Alessio Danilo Inchingolo, Gianna Dipalma
PURPOSE OF REVIEW: This review critically examines interconnected health domains like gut microbiome, bone health, interleukins, chronic periodontitis, and coronavirus disease 2019 (COVID-19), offering insights into fundamental mechanisms and clinical implications, contributing significantly to healthcare and biomedical research. RECENT FINDINGS: This review explores the relationship between gut microbiome and bone health, a growing area of study. It provides insights into skeletal integrity and potential therapeutic avenues...
April 12, 2024: Current Opinion in Endocrinology, Diabetes, and Obesity
#399
JOURNAL ARTICLE
Rachna Dhingra, Satinath Sarangi, Pranab Chatterjee, Arkaprabha Gun, Swarup Sarkar
Leakage of methyl isocyanate from the Union Carbide plant in Bhopal, India, killed thousands and left deleterious trans-generational effects. Gas-exposed populations experience higher rates of lung and metabolic diseases, and immune dysregulation, all associated with adverse outcomes in coronavirus disease 2019 (COVID-19). We used publicly available, official data from government sources to estimate COVID-19-associated crude mortality in populations with and without a history of gas exposure. Overall, there were 1240 deaths among patients hospitalized with known COVID-19 in Bhopal, of which 453 (36...
April 8, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
#400
JOURNAL ARTICLE
Karim Asi, Daniel Gorelik, Tariq Syed, Apurva Thekdi, Yin Yiu
Introduction The coronavirus disease 2019 (COVID-19) pandemic led to the more common use of venovenous (VV) extracorporeal membrane oxygenation (ECMO) for adults with acute respiratory distress syndrome (ARDS). While tracheostomy is generally understood to decrease the risks of prolonged endotracheal intubation, there is conflicting data regarding the benefit of tracheostomy in patients on ECMO. The purpose of this study is to determine whether ECMO cannulation before tracheostomy impacted patient outcomes...
March 2024: Curēus
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
