Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#41
RANDOMIZED CONTROLLED TRIAL
Neal S Kleiman, Nicolas M Van Mieghem, Michael J Reardon, Hemal Gada, Mubashir Mumtaz, Peter Skov Olsen, John Heiser, William Merhi, Stanley Chetcuti, G Michael Deeb, Atul Chawla, Bob Kiaii, Patrick Teefy, Michael W A Chu, Steven J Yakubov, Stephan Windecker, Andrew D Althouse, Suzanne J Baron
BACKGROUND: Symptomatic patients with severe aortic stenosis (AS) at high risk for surgical aortic valve replacement (SAVR) sustain comparable improvements in health status over 5 years after transcatheter aortic valve replacement (TAVR) or SAVR. Whether a similar long-term benefit is observed among intermediate-risk AS patients is unknown. OBJECTIVES: The purpose of this study was to assess health status outcomes through 5 years in intermediate risk patients treated with a self-expanding TAVR prosthesis or SAVR using data from the SURTAVI (Surgical Replacement and Transcatheter Aortic Valve Implantation) trial...
April 22, 2024: JACC. Cardiovascular Interventions
#42
REVIEW
Titus Hutch Jr Yi Zheng Yim, Kok Yang Tan
Amidst trends of a rapidly ageing population with better surgical outcomes for geriatric patients, it is imperative to consider outcome measures beyond mortality and morbidity rates. In fact, the preservation of one's postoperative function has been cited as a key priority for older adults and is a crucial determinant of postoperative independence and survival. This review aims to examine the prevalence of perioperative function reporting amongst older surgical patients undergoing elective major abdominal surgery for cancer...
April 17, 2024: European Journal of Surgical Oncology
#43
JOURNAL ARTICLE
Kanal Singh, Kevin Rubenstein, Viviane Callier, Katy Shaw-Saliba, Adam Rupert, Robin Dewar, Sylvain Laverdure, Helene Highbarger, Perrine Lallemand, Meei-Li Huang, Keith R Jerome, Reigran Sampoleo, Margaret G Mills, Alexander L Greninger, Kavita Juneja, Danielle Porter, Constance A Benson, Walla Dempsey, Hana M El Sahly, Chris Focht, Nikolaus Jilg, Catharine I Paules, Rekha R Rapaka, Timothy M Uyeki, H Clifford Lane, John Beigel, Lori E Dodd
BACKGROUND: Although antivirals remain important for the treatment COVID-19, methods to assess treatment efficacy are lacking. Here, we investigated the impact of remdesivir on viral dynamics and their contribution to understanding antiviral efficacy in the multicenter ACTT-1 clinical trial that randomized patients to remdesivir or placebo. METHODS: Longitudinal specimens collected during hospitalization from a substudy of 642 COVID-19 patients were measured for viral RNA (upper respiratory tract and plasma), viral nucleocapsid antigen (serum), and host immunologic markers...
April 24, 2024: Journal of Infectious Diseases
#44
JOURNAL ARTICLE
Niki Tadayon, Mostafa Mousavizadeh, Fateme Yousefimoghaddam, Faezeh Jadidian, Mohammadmoein Mirhosseini, Naser Hadavand
Introduction: The preference for endovascular techniques in treating varicose veins, particularly in the great saphenous vein (GSV), has increased due to their minimally invasive nature and reduced complications. Post-operative care, especially involving compression therapy, remains crucial to improve outcomes, prevent varicose vein recurrence, and enhance overall recovery. This study aimed to evaluate the efficacy of eccentric compression therapy compared to alternative post-operative care methods following endovenous laser treatment (EVLT) for GSV insufficiency...
2024: Journal of Lasers in Medical Sciences
#45
JOURNAL ARTICLE
Ying Gao, Yun Tang, Ting Yu, Ying Ding, Yilu Chen, Wei Ye, Changlin Zhao, Rongxin Lu
BACKGROUND: An idiopathic macular hole (IMH) is a full-thickness anatomic defect extending from the internal limiting membrane to the photoreceptor layer of the macula without any known cause. Recently, clinical laboratory markers of systemic inflammatory status derived from complete blood counts have been evaluated in ocular diseases. This study aimed to explore whether they could predict the development and progression of IMHs. METHODS: A retrospective review of 36 patients with IMH and 36 sex-and-age-matched patients with cataracts was conducted...
April 23, 2024: BMC Ophthalmology
#46
JOURNAL ARTICLE
Jiangang Xie, Linxiao Wang, Yunyun Xu, Yuexiang Ma, Lingqin Zhang, Wen Yin, Yang Huang
BACKGROUND: The incidence of exertional heat stroke (EHS) escalates during periods of elevated temperatures, potentially leading to persistent cognitive impairment postrecovery. Currently, effective prophylactic or therapeutic measures against EHS are nonexistent. METHODS: The selection of days 14 and 23 postinduction for detailed examination was guided by TEM of neuronal cells and HE staining of intestinal villi and the hippocampal regions. Fecal specimens from the ileum and cecum at these designated times were analyzed for changes in gut microbiota and metabolic products...
April 23, 2024: BMC Microbiology
#47
JOURNAL ARTICLE
Shichao Zhang, Guoping Cai, Zhe Ge
OBJECTIVE: Peroneus Longus Tendon (PLT), a viable anterior cruciate ligament (ACL) graft, shares similar biomechanics, making it suitable for reconstruction. Controversy exists over whether PLT transplants affects the donor ankle joint. The purpose of this study was to examine the recovery of knee joint function following arthroscopic ACL restoration using autologous PLT and its influence on the donor ankle joint. METHODS: A retrospective analysis was conducted on 65 patients with ACL rupture who underwent PLT graft reconstruction in our hospital from January 2016 to December 2021...
April 22, 2024: Orthopaedic Surgery
#48
JOURNAL ARTICLE
Ju-Eun Kim, Hyunwoo Kim, Eugene J Park, Daniel K Park
STUDY DESIGN: Retrospective study. OBJECTIVE: This study compared the fusion and subsidence rate and clinical outcomes when using different-sized static PEEK cages in BE-TLIF. SUMMARY OF BACKGROUND DATA: Biportal endoscopic techniques for transforaminal lumbar interbody fusion (BE-TLIF) have been shown to have similar clinical and fusion outcomes with faster clinical recovery in comparison to tubular surgery. Subsidence of the interbody, however, could be a complication...
April 23, 2024: Clinical Spine Surgery
#49
JOURNAL ARTICLE
Kristi Elisabeth Heiberg, Monica Beckmann, Vigdis Bruun-Olsen
BACKGROUND: Older people with hip fracture are often medically frail, and many do not regain their walking ability and level of physical activity. The aim of this study was to examine the relationship between pre-fracture recalled mobility, fear of falling, physical activity, walking habits and walking speed one year after hip fracture. METHODS: The study had a longitudinal design. Measurements were performed 3-5 days postoperatively (baseline) and at one year after the hip fracture...
April 22, 2024: BMC Geriatrics
#50
JOURNAL ARTICLE
Jonathan Z Pan, Zhanqiang Wang, Wei Sun, Peipei Pan, Wei Li, Yongtao Sun, Shoulin Chen, Amity Lin, Wulin Tan, Liangliang He, Jacob Greene, Virginia Yao, Lijun An, Rich Liang, Qifeng Li, Jessica Yu, Lingyi Zhang, Nikolaos Kyritsis, Xuan Duong Fernandez, Sara Moncivais, Esmeralda Mendoza, Pamela Fung, Gongming Wang, Xinhuan Niu, Qihang Du, Zhaoyang Xiao, Yuwen Chang, Peiyuan Lv, J Russell Huie, Abel Torres-Espin, Adam R Ferguson, Debra D Hemmerle, Jason F Talbott, Philip R Weinstein, Lisa U Pascual, Vineeta Singh, Anthony M DiGiorgio, Rajiv Saigal, William D Whetstone, Geoffrey T Manley, Sanjay S Dhall, Jacqueline C Bresnahan, Mervyn Maze, Xiangning Jiang, Neel S Singhal, Michael S Beattie, Hua Su, Zhonghui Guan
BACKGROUND: Although many molecules have been investigated as biomarkers for spinal cord injury (SCI) or ischemic stroke, none of them are specifically induced in central nervous system (CNS) neurons following injuries with low baseline expression. However, neuronal injury constitutes a major pathology associated with SCI or stroke and strongly correlates with neurological outcomes. Biomarkers characterized by low baseline expression and specific induction in neurons post-injury are likely to better correlate with injury severity and recovery, demonstrating higher sensitivity and specificity for CNS injuries compared to non-neuronal markers or pan-neuronal markers with constitutive expressions...
April 2024: Clinical and Translational Medicine
#51
JOURNAL ARTICLE
Felipe Agudelo-Hernández, Ana Giraldo Alvarez, Rodrigo Rojas-Andrade
Based on the need to implement strategies to reduce recovery gaps in mental health with the community as axes of recovery, the objective of the present study was to assess the impact on psychosocial disability and care continuity in individuals with suicidal behavior, of the clinical and community components of the Mental Health Gap Action Program (mhGAP), versus exclusive psychiatric care. For this, a controlled community trial carried out in 2023 was conducted, comprising intervention groups: Support Group (SG), mhGAP Group (mhGAPG) and a Control Group (CG)...
April 22, 2024: Psychological Reports
#52
JOURNAL ARTICLE
Shishi Chen, Wanying Zhang, Dingyu Wang, Zhaoming Chen
INTRODUCTION: Gait ability is often cited by stroke survivors. Robot-assisted gait training (RAGT) can help stroke patients with lower limb motor impairment regain motor coordination. EVIDENCE ACQUISITION: PubMed, Cochrane Library, Embase were systematically searched until September 2023, to identify randomized controlled trials presenting: stroke survivors as participants; RAGT as intervention; conventional rehabilitation as a comparator; gait assessment, through scales or quantitative parameters, as outcome measures...
April 22, 2024: European Journal of Physical and Rehabilitation Medicine
#53
Shiji Chalipat, Jyothsna Sree Madala, Sanjay Chavan, Sudhir Malwade, Shilpa Baviskar
Critical illness polyneuropathy (CIP) and myopathy (CIM) are underreported conditions in critically ill children with prolonged intensive care unit stays and mechanical ventilation. We report a case of a 10-year-old boy with pneumococcal meningoencephalitis with severe sepsis and multiorgan dysfunction. The child required prolonged ventilation, sedation, and inotropic support. He had repeated extubation failures and the development of quadriparesis with areflexia. Electrophysiology studies were consistent with CIP with acute motor and sensory axonal polyneuropathy and elevated muscle enzymes...
March 2024: Curēus
#54
REVIEW
Andreas Papaleontiou, Andréa M Poupard, Uday D Mahajan, Panteleimon Tsantanis
Anterior cruciate ligament (ACL) injury is very common, especially in young athletic individuals who injure themselves during sports involving pivoting actions. Management options include conservative management, which involves progressive physical therapy, educating the patient on how to prevent instability, and the use of a hinged knee brace. Surgical management involves reconstruction of the torn ligament using an autograft or an allograft and ACL repair where the torn ligament is affixed back to the tibia or femur...
March 2024: Curēus
#55
EDITORIAL
Zukhruf Zain, Mohammed Khaleel I Kh Almadhoun, Lara Alsadoun, Syed Faqeer Hussain Bokhari
Enhanced recovery after surgery (ERAS) protocols have transformed perioperative care by implementing evidence-based strategies to hasten patient recovery, decrease complications, and shorten hospital stays. However, challenges such as inconsistent adherence and the need for personalized adjustments persist, prompting exploration into innovative solutions. The emergence of artificial intelligence (AI) and machine learning (ML) offers a promising avenue for optimizing ERAS protocols. While ERAS emphasizes preoperative optimization, minimally invasive surgery (MIS), and standardized postoperative care, challenges such as adherence variability and resource constraints impede its effectiveness...
March 2024: Curēus
#56
JOURNAL ARTICLE
Yuan Yuan Li, Juan Peng, Yuan Yang Ping, Weng Jia Jun, Yan'e Lu, Jia Jia Liu, Shi Kun Xu, Li Hua Guan, Dong Huang, Qi Bing Wang, Ju Ying Qian, Ze Xin Zhao, Ya Bin Wei, Jun Bo Ge, Xiao Huang
BACKGROUND: The presence of mental health conditions is pervasive in patients who experienced acute myocardial infarction (AMI), significantly disrupting their recovery. Providing timely and easily accessible psychological interventions using virtual reality-based cognitive-behavioural therapy (VR-CBT) could potentially improve both acute and long-term symptoms affecting their mental health. AIMS: We aim to examine the effectiveness of VR-CBT on anxiety symptoms in patients with AMI who were admitted to the intensive care unit (ICU) during the acute stage of their illness...
2024: General Psychiatry
#57
JOURNAL ARTICLE
Nicholas Sauder, Niels Brinkman, George E Sayegh, Meredith Grogan Moore, Karl Koenig, Kevin Bozic, Jay Patel, Prakash Jayakumar
BACKGROUND: Symptoms of depression have been associated with greater incapability following total hip arthroplasty (THA). A brief, 2-question, measure of symptoms of depression - the Patient Health Questionnaire 2 (PHQ-2) - may be sufficient to measure associations with the magnitude of incapability during recovery from THA. This study investigated whether preoperative symptoms of depression (measured with the PHQ-2) correlated with levels of incapability 6 weeks and 6 months after THA, accounting for demographic and clinical factors...
April 18, 2024: Journal of Arthroplasty
#58
JOURNAL ARTICLE
Patricia A Lee King, SuYeon Lee, Dan Weiss, David Aaby, Tamela Milan-Alexander, Ann Eb Borders
BACKGROUND: Maternal deaths resulting from opioid use disorder (OUD) have been rising across the United States. OUD among pregnant persons is associated with adverse pregnancy outcomes including preterm birth along with racial disparities in optimal OUD care. OBJECTIVE: We aimed to evaluate whether the Illinois Perinatal Quality Collaborative's (ILPQC) implementation of the Mothers and Newborns affected by Opioids - Obstetric quality improvement initiative was associated with improvement of OUD identification, provision of optimal OUD care for birthing patients, and reduction in racial gaps of optimal OUD care...
April 18, 2024: American Journal of Obstetrics and Gynecology
#59
REVIEW
Clevio Desouza, Vijay Shetty
IMPORTANCE: Partial-thickness rotator cuff tears (PTRCTs) commonly affect overhead athletes, leading to a decline in sports performance. Platelet-rich plasma (PRP) is being explored as an alternative treatment modality for individuals with PTRCTs, to reduce discomfort and enhance functional recovery. We conducted a systematic review study of randomized controlled clinical trials to determine the effectiveness of PRP in treating PTRCTs. AIM: To determine the effectiveness of PRP in treating PTRCTs...
April 17, 2024: Journal of ISAKOS
#60
JOURNAL ARTICLE
M Bryant Howren, Alan J Christensen, Nitin A Pagedar
PURPOSE: The experience of long-term pain in head and neck cancer (HNC) survivors is important but has received less attention in the HNC literature. The present study sought to examine the prevalence of pain from 2 to 5 years postdiagnosis and its association with HNC-specific health-related quality of life. MATERIALS & METHODS: Prospective observational study at a single-institution tertiary care center. Pain was measured using a single item ranging from 0 to 10 with 0 representing no pain and 10 representing worst pain possible at 2 through 5 years postdiagnosis...
April 16, 2024: American Journal of Otolaryngology
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
