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JOURNAL ARTICLE
Saif Zaman, Fiona Dierksen, Avery Knapp, Stefan P Haider, Gaby Abou Karam, Adnan I Qureshi, Guido J Falcone, Kevin N Sheth, Seyedmehdi Payabvash
The mortality rate of acute intracerebral hemorrhage (ICH) can reach up to 40%. Although the radiomics of ICH have been linked to hematoma expansion and outcomes, no research to date has explored their correlation with mortality. In this study, we determined the admission non-contrast head CT radiomic correlates of survival in supratentorial ICH, using the Antihypertensive Treatment of Acute Cerebral Hemorrhage II (ATACH-II) trial dataset. We extracted 107 original radiomic features from n = 871 admission non-contrast head CT scans...
April 30, 2024: Diagnostics
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JOURNAL ARTICLE
Rashid A Ahmed, Joshua A Hirsch, Thabele M Leslie-Mazwi, Aman B Patel, Robert W Regenhardt
No abstract text is available yet for this article.
May 10, 2024: Journal of Neurointerventional Surgery
#23
JOURNAL ARTICLE
Chen Gong, Liping Huang, Jiacheng Huang, Liyuan Chen, Weilin Kong, Yangmei Chen, Fengli Li, Chang Liu
OBJECTIVES: To investigate the association between venous outflow (VO) profiles and outcomes among acute ischemic stroke caused by anterior circulation large vessel occlusion (AIS-LVO) patients who had undergone endovascular treatment (EVT) in the late window of 6-24 h from stroke onset. METHODS: This was a post-hoc analysis of our preceding RESCUE-BT trial, with findings validated in an external cohort. Baseline computed tomographic angiography (CTA) was performed to assess VO using the Cortical Vein Opacification Score (COVES)...
May 9, 2024: European Radiology
#24
JOURNAL ARTICLE
Yu-Ming Chang, Chun-Min Wang, Kang-Po Lee, Po-Chun Shen, Po-Yu Lin, Chi-Hung Liu, Sheng-Hsiang Lin, Chih-Hung Chen, Meng-Tsang Hsieh, Pi-Shan Sung
BACKGROUND: Current guidelines advocate for maintaining BP level below 180/105 mmHg during EVT, determining the safe lower boundary remains primarily consensus-driven by experts. This study aims to delve into the correlation between various targets of lower boundary for systolic and diastolic BP (SBP and DBP) during EVT and 3-month functional outcomes. METHODS: A cohort study was conducted across two EVT-capable centers, enrolling patients with large artery occlusion undergoing EVT within 8 h of stroke onset...
May 8, 2024: Journal of the Formosan Medical Association
#25
JOURNAL ARTICLE
Liang Zhang, Jia'li Gao, Yu Liao, Jia'xing Lin, Min Guan, Sheng'ming Huang, Bing Yang, Zhong'yuan Cheng, Xin'yi Leng, Hong'yu Qiao, Li'an Huang
PURPOSE: To examine the relationship between hyperdense artery sign/susceptibility vessel sign (HAS/SVS) and thrombus composition, and evaluate the effect of HAS/SVS status on the association between first-line thrombectomy techniques and outcomes in patients with acute anterior-circulation large vessel occlusion (LVO). MATERIALS AND METHODS: From January 2018 to June 2021, 103 consecutive acute anterior-circulation LVO patients (75 [63.1%] male; median age, 66 years) who underwent thrombectomy, and for whom the removed clot was available for histological analyses were retrospectively reviewed...
May 7, 2024: Journal of Vascular and Interventional Radiology: JVIR
#26
JOURNAL ARTICLE
Lihua Wei, Xiaolin Zhao, Jiaqi Luo, Mengxuan Xiao, Bingbing Li, Zhiliang Zhu, Huanhuan Fan, Wenting Lu, Zhenzhou Lin, Yongming Wu, Suyue Pan, Xianghong Liu, Zhong Ji, Kaibin Huang
BACKGROUND: White matter hyperintensity (WMH) burden may lead to poor clinical outcomes after endovascular thrombectomy (EVT). But the relationship between WMH burden and cerebral edema (CED) is unclear. PURPOSE: To examine the association between WMH burden and CED and functional outcome in patients treated with EVT. STUDY TYPE: Retrospective. SUBJECT: 344 patients with acute anterior circulation large-vessel occlusion stroke who received EVT at two comprehensive stroke centers...
May 9, 2024: Journal of Magnetic Resonance Imaging: JMRI
#27
JOURNAL ARTICLE
Yusuke Takahashi, Takahiro Ono, Junta Moroi, Jun Maruya, Shuntaro Togashi, Takatsugu Abe, Hajime Nakae, Yasuo Fujita, Shinichi Takahashi, Hiroaki Shimizu
OBJECTIVE: Early intervention with mechanical thrombectomy (MT) is expected to improve the functional outcome in patients with large vessel occlusion (LVO); however, a method for the effective detection of these patients in a prehospital setting and early transport to MT-capable hospitals has not been established. This study aimed to analyze the clinical impact and diagnostic performance of the emergent large vessel occlusion (ELVO) screen and its influence on the transportation time...
2024: Journal of neuroendovascular therapy
#28
JOURNAL ARTICLE
Byeong Jin Ha, Sang Mook Kang, Bo Mi Choi, Jin Hwan Cheong, Je Il Ryu, Yu Deok Won, Myung-Hoon Han
Recurrence after stroke is common, and associated with a high mortality rate. Degradation of the elastic tissue in the arterial wall has been shown to aggravate atherosclerosis in blood vessels. Considering that type 1 collagen is present in both bone and vascular smooth muscle cells, we explored whether osteoporotic conditions affect the likelihood of stroke recurrence in postmenopausal women following atherosclerotic ischemic stroke. To determine actual bone mineral density (BMD), the Hounsfield unit values in the frontal skull were evaluated using brain computed tomography (CT) scans taken at admission...
May 15, 2024: Heliyon
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JOURNAL ARTICLE
Jiaxiang You, Xiaoxi Li, Jun Xia, Haopeng Li, Jun Wang
BACKGROUND AND PURPOSE: Hemorrhagic transformation remains a potentially devastating complication of acute ischemic stroke. We aimed to evaluate whether the hypoperfusion intensity ratio (HIR), a parameter derived from CT perfusion imaging, is associated with the development of hemorrhagic transformation in patients with anterior large-artery occlusion who had undergone thrombectomy. MATERIALS AND METHODS: We retrospectively reviewed data from consecutive acute ischemic stroke patients who had achieved successful recanalization (thrombolysis in cerebral infarction score ≥ 2b) between January 2020 and December 2023...
May 7, 2024: AJNR. American Journal of Neuroradiology
#30
JOURNAL ARTICLE
Low-profile mechanical thrombectomy devices for large vessel occlusion in pediatric ischemic stroke.
Soliman Oushy, Andrew Garton, Darren B Orbach, Alfred Pokmeng See
BACKGROUND: Mechanical thrombectomy (MT) is a well-established treatment modality for large vessel occlusion (LVO) in adults, but there are limited data in the pediatric population. The rarity of the condition makes prospective trial design difficult, and therefore evaluation of MT devices and outcomes is sparse. In pediatric LVO cases, some newer devices may be appropriate for use in revascularization procedures. Furthermore, illustrative specific device-access combinations have rarely been presented in young patients under the age of 5 years...
May 6, 2024: Journal of Neurointerventional Surgery
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JOURNAL ARTICLE
Nanthiya Sujijantarat, Daniela Renedo, Joseph Antonios, Andrew B Koo, Abdelaziz Amllay, Kamil Nowicki, Branden J Cord, Ryan Hebert, Adam de Havenon, Kevin N Sheth, Nils H Petersen, Charles Matouk
BACKGROUND: Transcarotid artery revascularization (TCAR) is an increasingly popular technique for the management of extracranial carotid stenosis. Its off-label use in the treatment of intracranial neurovascular disease is poorly described. Our objective is to describe the use of a dedicated open transcarotid access system for the treatment of neurovascular pathologies other than extracranial carotid stenosis. METHODS: We conducted a retrospective review of a prospectively maintained database of consecutive patients who underwent treatment of neurovascular disease at a single academic center using the ENROUTE Transcarotid Arterial Sheath...
May 6, 2024: Journal of Neurointerventional Surgery
#32
RANDOMIZED CONTROLLED TRIAL
Vincent Costalat, Tudor G Jovin, J F Albucher, Christophe Cognard, Hilde Henon, Nasreddine Nouri, Benjamin Gory, Sebastien Richard, Gaultier Marnat, Igor Sibon, Federico Di Maria, Mariam Annan, Grégoire Boulouis, Pere Cardona, Michael Obadia, Michel Piotin, Romain Bourcier, Benoit Guillon, Sophie Godard, Anne Pasco-Papon, Omer F Eker, Tae-Hee Cho, Guillaume Turc, Olivier Naggara, Stéphane Velasco, Matthias Lamy, Frédéric Clarençon, Sonia Alamowitch, Arturo Renu, Laurent Suissa, Hervé Brunel, Jean-Christophe Gentric, Serge Timsit, Chantal Lamy, Cyril Chivot, Francisco Macian-Montoro, Charbel Mounayer, Ozlem Ozkul-Wermester, Chrysanthi Papagiannaki, Valérie Wolff, Raoul Pop, Anna Ferrier, Emmanuel Chabert, Frédéric Ricolfi, Yannick Béjot, Elena Lopez-Cancio, Pedro Vega, Laurent Spelle, Christian Denier, Mònica Millán, Juan F Arenillas, Mikael Mazighi, Emmanuel Houdart, Maria Del Mar Freijo, Alain Duhamel, Nerses Sanossian, David S Liebeskind, Julien Labreuche, Bertrand Lapergue, Caroline Arquizan
BACKGROUND: The use of thrombectomy in patients with acute stroke and a large infarct of unrestricted size has not been well studied. METHODS: We assigned, in a 1:1 ratio, patients with proximal cerebral vessel occlusion in the anterior circulation and a large infarct (as defined by an Alberta Stroke Program Early Computed Tomographic Score of ≤5; values range from 0 to 10) detected on magnetic resonance imaging or computed tomography within 6.5 hours after symptom onset to undergo endovascular thrombectomy and receive medical care (thrombectomy group) or to receive medical care alone (control group)...
May 9, 2024: New England Journal of Medicine
#33
JOURNAL ARTICLE
Jiarui Wang, Yongqiang Cui, Xiangkai Kong, Bin Du, Tian Lin, Xiaoyun Zhang, Dongxu Lu, Li Liu, Juan Du
BACKGROUND: Chronic lung and heart diseases are more likely to lead an intensive end point after stroke onset. We aimed to investigate characteristics and outcomes of endovascular thrombectomy (EVT) in patients with acute large vessel occlusion stroke (ALVOS) and identify the role of comorbid chronic cardiopulmonary diseases in ALVOS pathogenesis. METHODS: In this single-center retrospective study, 191 consecutive patients who underwent EVT due to large vessel occlusion stroke in neurological intensive care unit were included...
May 7, 2024: BMC Neurology
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MULTICENTER STUDY
Thanh N Nguyen, Raul G Nogueira, Muhammad M Qureshi, Simon Nagel, Jean Raymond, Mohamad Abdalkader, Jelle Demeestere, João Pedro Marto, Sunil A Sheth, Volker Puetz, Anne Dusart, Patrik Michel, Marc Ribo, Osama O Zaidat, James E Siegler, Diogo C Haussen, Daniel Strbian, Hilde Henon, Mahmoud H Mohammaden, Markus A Möhlenbruch, Marta Olive-Gadea, Ajit S Puri, Simon Winzer, Johannes Kaesmacher, Piers Klein, Liisa Tomppo, Francois Caparros, João Nuno Ramos, Mouhammad A Jumaa, Syed F Zaidi, Nicolas Martinez-Majander, Stefania Nannoni, Lieselotte Vandewalle, Flavio Bellante, Mudassir Farooqui, Sergio Salazar-Marioni, Pekka Virtanen, Daniel P O Kaiser, Anke Wouters, Rita Ventura, Jessica Jesser, Adnan Mujanovic, Liqi Shu, Alicia C Castonguay, Zain Mansoor, Zhongming Qiu, Hesham E Masoud, Manuel Requena, Erno Peltola, Wei Hu, Eugene Lin, Kanta Tanaka, Charlotte Cordonnier, Daniel Roy, Shadi Yaghi, Davide Strambo, Hiroshi Yamagami, Urs Fischer, Tudor G Jovin, Robin Lemmens, Peter A Ringleb, Santiago Ortega-Gutierrez
BACKGROUND AND OBJECTIVES: There is uncertainty whether patients with large vessel occlusion (LVO) presenting in the late 6-hour to 24-hour time window can be selected for endovascular therapy (EVT) by noncontrast CT (NCCT) and CT angiography (CTA) for LVO detection. We evaluated the clinical outcomes of patients selected for EVT by NCCT compared with those medically managed in the extended time window. METHODS: This multinational cohort study was conducted at 66 sites across 10 countries...
May 28, 2024: Neurology
#35
JOURNAL ARTICLE
Marialuisa Zedde, Ilaria Grisendi, Federica Assenza, Manuela Napoli, Claudio Moratti, Giovanna Di Cecco, Claudio Pavone, Lara Bonacini, Serena D'Aniello, Franco Valzania, Rosario Pascarella
INTRODUCTION: Calcified arterial cerebral embolism is a rare occurrence among large and medium vessel occlusions causing ischemic stroke and its diagnosis and treatment is a challenge. The sources of calcified embolism might be a calcific atheroma from the aortic arch and carotid artery, but also heart valve disease has been reported in the literature. Calcified embolism is frequently simultaneous on multiple vascular territories. The prognosis of patients is usually poor, including patients treated by using endovascular thrombectomy (EVT) and this diagnosis could be easily missed in the acute phase...
May 6, 2024: Neurological Sciences
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JOURNAL ARTICLE
Venkata Subbaih Arunachalam, Smily Sharma, Jineesh Valakkada, Anoop Ayyappan, Jayakrishnan Radhakrishnan, Santhosh Kumar Kannath
BACKGROUND: Arteriovenous fistulas involving the anterior abdominal wall can result from trauma. Such fistulas may remain asymptomatic and undetected for a prolonged duration of time. They tend to recruit multiple arterial feeders with remodelling in the feeding arteries, making them challenging to treat. CASE PRESENTATION: We discuss a rare case of a 60-year-old male who presented with complaints of a progressive painless swelling in right lower abdomen. There was a history of blunt injury to abdomen at the same site during alleged road traffic accident 3 years ago...
May 6, 2024: CVIR Endovascular
#37
JOURNAL ARTICLE
Meijuan Dong, Chun Chen, Wei Chen, Kun An
BACKGROUND: Post-thrombectomy intraparenchymal hyperdensity (PTIH) in patients with acute anterior circulation large vessel occlusion is a common CT sign associated with a higher incidence of futile reperfusion (FR). We aimed to develop a nomogram to predict FR specifically in patients with PTIH. METHODS: We retrospectively collected information on patients with acute ischemic stroke who underwent endovascular thrombectomy (EVT) at two stroke centers. A total of 398 patients with PTIH were included to develop and validate the nomogram, including 214 patients in the development cohort, 92 patients in the internal validation cohort and 92 patients in the external validation cohort...
2024: Frontiers in Neurology
#38
Saarang Patel, Jeffrey Treiber, Jeremiah N Johnson
We report a rare case of acute ischemic stroke from concurrent large vessel occlusions (LVOs) and subsequent successful mechanical thrombectomy revascularization in a patient with active coronavirus disease 2019 (COVID-19) pneumonia. A 59-year-old woman presented to the emergency department after one week of intermittent chest pain, dyspnea, and diarrhea found to have COVID-19 pneumonia. On hospital day three, the patient developed acute altered mental status and hemiparesis with a National Institutes of Health Stroke Scale (NIHSS) of 22...
April 2024: Curēus
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JOURNAL ARTICLE
Kentaro Suzuki, Takehiro Katano, Shinichiro Numao, Yuji Nishi, Akihito Kutsuna, Takuya Kanamaru, Tomonari Saito, Junya Aoki, Yasuhiro Nishiyama, Kazumi Kimura
BACKGROUND AND OBJECTIVE: Whether intracranial hemorrhage (ICH) detected using magnetic resonance imaging (MRI) affects the clinical outcomes of patients with large-vessel occlusion (LVO) treated with mechanical thrombectomy (MT) remains unclear. This study investigated the clinical features of ICH after MT detected solely by MRI. METHODS: This was a retrospective analysis of patients with acute ischemic stroke and occlusion of the internal carotid artery or middle cerebral artery treated with MT between April 2011 and March 2021...
April 12, 2024: Journal of the Neurological Sciences
#40
JOURNAL ARTICLE
Thanapoom Taweephol, Pitsinee Saksit, Akarin Hiransuthikul, Pongpat Vorasayan, Wasan Akarathanawat, Aurauma Chutinet
BACKGROUND: Ischemic stroke (IS) is one of the leading causes of death among non-communicable diseases in Thailand. Patients who have survived an IS are at an increased risk of developing recurrent IS, which can result in worse outcomes and post-stroke complications. OBJECTIVES: The study aimed to investigate the incidence of recurrent IS among patients with first-ever IS during a one-year follow-up period and to determine its associated risk factors. METHODS: Adult patients (aged ≥ 18 years) who were hospitalized at the Stroke Center, King Chulalongkorn Memorial Hospital (KCMH) in Bangkok, Thailand, due to first-ever IS between January and December 2019 and had at least one follow-up visit during the one-year follow-up period were included in this retrospective cohort study...
May 4, 2024: BMC Neurology
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