keyword
https://read.qxmd.com/read/38650523/overweight-obesity-gestational-weight-gain-postpartum-weight-retention-and-maternal-neonatal-complications-in-the-military
#1
JOURNAL ARTICLE
Rebecca A Krukowski, Erin Solomon, Juan Lang, Emily Stone, Wen You, Rosemary Estevez Burns, Carol Copeland, Zoran Bursac, Marion E Hare, Teresa M Waters
OBJECTIVE: The objective of this study was to examine the prevalence of overweight/obesity and excessive gestational weight gain (GWG) among military beneficiaries and to assess associations of these risk factors with maternal/neonatal complications and substantial postpartum weight retention (PPWR). METHODS: We obtained data for 48,391 TRICARE beneficiaries who gave birth in 2018 or 2019 in the United States. We used logistic regression and ANOVA to examine relationships among overweight/obesity, GWG, maternal/neonatal complications, and substantial PPWR...
May 2024: Obesity
https://read.qxmd.com/read/38646101/perinatal-exposure-to-atazanavir-based-antiretroviral-regimens-in-a-mouse-model-leads-to-differential-long-term-motor-and-cognitive-deficits-dependent-on-the-nrti-backbone
#2
JOURNAL ARTICLE
Shreya H Dhume, Kayode Balogun, Ambalika Sarkar, Sebastian Acosta, Howard T J Mount, Lindsay S Cahill, John G Sled, Lena Serghides
BACKGROUND: Combination antiretroviral therapy (ART) use in pregnancy has been pivotal in improving maternal health and reducing perinatal HIV transmission. However, children born HIV-exposed uninfected fall behind their unexposed peers in several areas including neurodevelopment. The contribution of in utero ART exposure to these deficits is not clear. Here we present our findings of neurocognitive outcomes in adult mice exposed in utero to ART. METHODS: Dams were treated with a combination of ritonavir-boosted atazanavir with either abacavir plus lamivudine (ABC/3TC + ATV/r) or tenofovir disoproxil fumarate plus emtricitabine (TDF/FTC + ATV/r), or water as a control, administered daily from day of plug detection to birth...
2024: Frontiers in Molecular Neuroscience
https://read.qxmd.com/read/38642652/carry-over-effects-of-maternal-late-gestation-heat-stress-on-granddaughter-s-growth-and-mammary-gland-development
#3
JOURNAL ARTICLE
Grace A Larsen, Jimena Laporta
Maternal (F0 ) exposure to late-gestation heat stress reduces their daughter's (F1 ) mammary gland fat pad mass (FP), parenchyma (PAR) mass, and epithelial cell proliferation when evaluated at birth and weaning, and go on to produce less milk in their first lactation. Herein, we investigated the effect of maternal late-gestation heat stress on whole-body growth and mammary development of their granddaughters (F2 ). Multiparous F0 cows had access to heat abatement (n = 41, shade, and active cooling via fans and water soakers) or not (n = 41, shade only) for the last 56 d of gestation during a subtropical summer...
April 18, 2024: Journal of Dairy Science
https://read.qxmd.com/read/38627679/all-cause-cardiovascular-disease-and-cancer-mortality-in-the-population-of-a-large-italian-area-contaminated-by-perfluoroalkyl-and-polyfluoroalkyl-substances-1980-2018
#4
JOURNAL ARTICLE
Annibale Biggeri, Giorgia Stoppa, Laura Facciolo, Giuliano Fin, Silvia Mancini, Valerio Manno, Giada Minelli, Federica Zamagni, Michela Zamboni, Dolores Catelan, Lauro Bucchi
BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) are associated with many adverse health conditions. Among the main effects is carcinogenicity in humans, which deserves to be further clarified. An evident association has been reported for kidney cancer and testicular cancer. In 2013, a large episode of surface, ground and drinking water contamination with PFAS was uncovered in three provinces of the Veneto Region (northern Italy) involving 30 municipalities and a population of about 150,000...
April 16, 2024: Environmental Health
https://read.qxmd.com/read/38617421/direct-potable-reuse-and-birth-defects-prevalence-in-texas-an-augmented-synthetic-control-method-analysis-of-data-from-a-population-based-birth-defects-registry
#5
JOURNAL ARTICLE
Jeremy M Schraw, Kara E Rudolph, Charles J Shumate, Matthew O Gribble
BACKGROUND: Direct potable reuse (DPR) involves adding purified wastewater that has not passed through an environmental buffer into a water distribution system. DPR may help address water shortages and is approved or is under consideration as a source of drinking water for several water-stressed population centers in the United States, however, there are no studies of health outcomes in populations who receive DPR drinking water. Our objective was to determine whether the introduction of DPR for certain public water systems in Texas was associated with changes in birth defect prevalence...
April 2024: Environmental Epidemiology
https://read.qxmd.com/read/38614423/environmentally-relevant-concentrations-of-benzophenones-exposure-disrupt-intestinal-homeostasis-impair-the-intestinal-barrier-and-induce-inflammation-in-mice
#6
JOURNAL ARTICLE
Yu-Jia Lin, Hong-Mei Li, Yan-Rong Gao, Ping-Fan Wu, Bin Cheng, Chen-Long Yu, Yu-Xin Sheng, Hai-Ming Xu
The aim of this study is to investigate the adverse effects of benzophenones (BPs) on the intestinal tract of mice and the potential mechanism. F1-generation ICR mice were exposed to BPs (benzophenone-1, benzophenone-2, and benzophenone-3) by breastfeeding from birth until weaning, and by drinking water after weaning until maturity. The offspring mice were executed on postnatal day 56, then their distal colons were sampled. AB-PAS staining, HE staining, immunofluorescence, Transmission Electron Microscope, immunohistochemistry, western blot and RT-qPCR were used to study the effects of BPs exposure on the colonic tissues of offspring mice...
April 11, 2024: Environmental Pollution
https://read.qxmd.com/read/38613006/a-study-of-fluid-intake-hydration-status-and-body-composition-of-pregnant-women-in-their-third-trimester-and-relationships-with-their-infant-s-birth-weight-in-china-a-prospective-cohort-study
#7
JOURNAL ARTICLE
Yongye Song, Fan Zhang, Xing Wang, Guotian Lin, Limin He, Zhixiong Lin, Na Zhang, Guansheng Ma
BACKGROUND: Water intake and hydration status may potentially influence maternal and child health. However, there is little research regarding this topic. OBJECTIVES: This study aimed to investigate pregnant women's total fluid intake (TFI) levels, hydration status, and body composition and further explore their relationship with infant birth weight. METHODS: A 7-day, 24 h fluid intake recorded was applied to determine participants' TFI levels...
March 27, 2024: Nutrients
https://read.qxmd.com/read/38610747/navigating-uncertain-waters-first-trimester-screening-s-role-in-identifying-neonatal-complications
#8
JOURNAL ARTICLE
Grzegorz Swiercz, Anna Zmelonek-Znamirowska, Karol Szwabowicz, Justyna Armanska, Karolina Detka, Marta Mlodawska, Jakub Mlodawski
Background : Contemporary diagnostic methods aimed at assessing neonatal outcomes predominantly rely on the medical history of pregnant women. Ideally, universal biomarkers indicating an increased risk of delivering infants in poor clinical condition, with a heightened likelihood of requiring hospitalization in a Neonatal Intensive Care Unit (NICU), would be beneficial for appropriately stratifying pregnant women into a high-risk category. Our study evaluated whether biochemical and ultrasonographical markers universally used in first-trimester screenings for non-heritable chromosomal aberrations could serve this purpose...
March 29, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38594754/the-socioeconomic-epidemiology-of-inherited-retinal-diseases-in-portugal
#9
JOURNAL ARTICLE
Ana Marta, João Pedro Marques, Cristina Santos, Luísa Coutinho-Santos, Sara Vaz-Pereira, José Costa, Pedro Arede, Raquel Félix, Sara Geada, Nuno Gouveia, Rui Silva, Margarida Baptista, Miguel Lume, Ricardo Parreira, Célia Azevedo Soares, Maria João Menéres, Carolina Lemos, João Melo Beirão
BACKGROUND: Inherited retinal diseases (IRDs) are a group of rare degenerative disorders of the retina that can lead to blindness from birth to late middle age. Knowing the target population and its resources is essential to better plan support measures. The aim of this study was to evaluate the socioeconomic characteristics of regions in Portugal where IRD patients reside to inform the planning of vision aid and rehabilitation intervention measures. RESULTS: This study included 1082 patients from 973 families, aged 3 to 92 years, with a mean age of 44...
April 9, 2024: Orphanet Journal of Rare Diseases
https://read.qxmd.com/read/38580145/programming-effects-of-intrauterine-hyperthermia-on-adrenal-gland-development
#10
JOURNAL ARTICLE
Anne R Guadagnin, Francisco Peñagaricano, Geoffrey E Dahl, Jimena Laporta
Maternal heat stress during late pregnancy can lead to intrauterine hyperthermia and affect fetal hypothalamic-pituitary-adrenal axis development and function. Herein, we investigated the effects of chronic environmental heat stress exposure of Holstein cows in the last 2 mo of gestation on their offspring's adrenal gland histomorphology and transcriptome. Cows in their last 54 ± 5 d of gestation were either heat-stressed (i.e., housed under the shade of a free stall barn) or provided heat-stress abatement via active cooling (i...
April 3, 2024: Journal of Dairy Science
https://read.qxmd.com/read/38578819/determinants-of-coexistence-of-undernutrition-and-anemia-among-under-five-children-in-rwanda-evidence-from-2019-20-demographic-health-survey-application-of-bivariate-binary-logistic-regression-model
#11
JOURNAL ARTICLE
Abebew Aklog Asmare, Yitateku Adugna Agmas
BACKGROUND: Undernutrition and anemia are significant public health issues among under-5 children, with potential long-term consequences for growth, development, and overall health. Thus, this study aims to conduct a bivariate binary logistic regression model by accounting for the possible dependency of childhood undernutrition and anemia. METHODS: The data came from the DHS program's measurement. A total of 3,206 under-five children were involved in this study...
2024: PloS One
https://read.qxmd.com/read/38564615/concurrence-of-anemia-and-stunting-and-associated-factors-among-children-aged-6-to-59-months-in-peru
#12
JOURNAL ARTICLE
Alessandra Rivera, Víctor Marín, Franco Romaní
Anemia and stunting are two health problems in the child population; therefore, their concurrence needs to be quantified. We estimated the prevalence of concurrent anemia and stunting (CAS) in children aged 6-59 months and identified the factors associated with this condition. The data came from the Demographic and Health Survey of Peru (DHS), 2022. The study design was cross-sectional and included 19,191 children. Height and hemoglobin measurement followed the specifications of National Health Institute of Peru...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38555037/limited-bedding-and-nesting-increases-ethanol-drinking-in-female-rats
#13
JOURNAL ARTICLE
B J Parks, P Salazar, L Morrison, M K McGraw, M Gunnell, J Tobacyk, L K Brents, M D Berquist
Prenatal opioid exposure (POE) and postnatal adverse experiences are early life adversities (ELA) that often co-occur and increase problematic alcohol (EtOH) drinking during adolescence. We investigated the relationship between POE, postnatal adversity, and adolescent EtOH drinking in rats. We also sought to determine whether ELAs affect alpha-adrenoceptor density in the brain because the noradrenergic system is involved in problematic alcohol drinking and its treatment. We hypothesized that the combination of POE and postnatal adversity will increase alcohol drinking in rats compared to rats with exposure to either adversity alone or to control...
March 28, 2024: Pharmacology, Biochemistry, and Behavior
https://read.qxmd.com/read/38549997/retracted-glucosamine-supplementation-in-premating-drinking-water-improves-within-litter-birth-weight-uniformity-of-rats-partly-through-modulating-hormone-metabolism-and-genes-involved-in-implantation
#14
https://read.qxmd.com/read/38547113/low-birth-weight-household-socio-economic-status-water-and-sanitation-are-associated-with-stunting-and-wasting-among-children-aged-6-23-months-results-from-a-national-survey-in-ghana
#15
JOURNAL ARTICLE
Hammond Yaw Addae, Mohammed Sulemana, Taminu Yakubu, Ambrose Atosona, Rafatu Tahiru, Fusta Azupogo
BACKGROUND: Stunting and wasting are key public health problems in Ghana that are significantly linked with mortality and morbidity risk among children. However, information on their associated factors using nationally representative data is scanty in Ghana. This study investigated the influence of Infant and Young Child Feeding (IYCF) indicators, socio-demographic and economic related factors, and water and sanitation on stunting and wasting, using nationally representative data in Ghana...
2024: PloS One
https://read.qxmd.com/read/38535579/detection-of-chlamydia-psittaci-in-the-genital-tract-of-horses-and-in-environmental-samples-a-pilot-study-in-sardinia
#16
JOURNAL ARTICLE
Gaia Muroni, Elisa Serra, Giovanni Paolo Biggio, Daniela Sanna, Raffaele Cherchi, Andrea Taras, Simonetta Appino, Cipriano Foxi, Giovanna Masala, Federica Loi, Valentina Chisu
The members of the Chlamydiaceae family are important pathogens that infect a wide range of vertebrate hosts, including humans. Among them, Chlamydia psittaci , historically considered as an avian agent, has recently been identified in livestock, primarily sheep and cattle, but also in horses, with the infection being linked to reproductive disorders, such as abortion, absorption of embryos, stillbirth, and the birth of weak foals. Much less is known about chlamydial infections in the Sardinian equine population...
March 7, 2024: Pathogens
https://read.qxmd.com/read/38525802/economic-evaluation-of-a-water-fluoridation-scheme-in-cumbria-uk
#17
JOURNAL ARTICLE
William Whittaker, Michaela Goodwin, Saima Bashir, Matt Sutton, Richard Emsley, Michael P Kelly, Martin Tickle, Tanya Walsh, Iain A Pretty
OBJECTIVES: The addition of fluoride to community drinking water supplies has been a long-standing public health intervention to improve dental health. However, the evidence of cost-effectiveness in the UK currently lacks a contemporary focus, being limited to a period with higher incidence of caries. A water fluoridation scheme in West Cumbria, United Kingdom, provided a unique opportunity to study the contemporary impact of water fluoridation. This study evaluates the cost-effectiveness of water fluoridation over a 5-6 years follow-up period in two distinct cohorts: children exposed to water fluoridation in utero and those exposed from the age of 5...
March 25, 2024: Community Dentistry and Oral Epidemiology
https://read.qxmd.com/read/38511756/does-dietary-total-antioxidant-capacity-relate-to-oxidative-stress-levels-in-water-immersion-during-labor-a-case-control-study
#18
JOURNAL ARTICLE
Tuğba Küçükkasap Cömert, Seval Yılmaz Ergani, Meltem Uğurlu, Funda Akpınar
OBJECTIVE: The aim of this study was to investigate the effect of water immersion during the first stage of labor on maternal and neonatal oxidative stress and the association between serum and dietary total antioxidant capacity. METHODS: Women were divided into two groups: those immersed in water during the first stage of labor (n=30) and those who had conventional birth (n=33). Total oxidative stress and total antioxidant status levels were examined in antepartum and postpartum maternal serum and neonatal cord blood samples...
2024: Revista da Associação Médica Brasileira
https://read.qxmd.com/read/38511211/postnatal-survival-of-phrenic-motor-neurons-is-promoted-by-bdnf-trkb-fl-signaling
#19
JOURNAL ARTICLE
Joline E Brandenburg, Matthew J Fogarty, Wen-Zhi Zhan, Leo A Kopper, Gary C Sieck
The number of motor neurons (MNs) declines precipitously during the final trimester before birth. Thereafter, the number of MNs remains relatively stable, with their connections to skeletal muscle dependent on neurotrophins, including brain-derived neurotrophic factor (BDNF) signaling through its high affinity full length tropomyosin related kinase receptor subtype B (TrkB.FL) receptor. As a genetic knockout of BDNF leads to extensive MN loss and postnatal death within 1-2 days after birth; we tested the hypothesis that postnatal inhibition of BDNF/TrkB...
March 21, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38504469/oligodendrocyte-progenitor-cells-fate-after-neonatal-asphyxia-puzzling-implications-for-the-development-of-hypoxic-ischemic-encephalopathy
#20
JOURNAL ARTICLE
Justyna Janowska, Justyna Gargas, Karolina Zajdel, Michal Wieteska, Kamil Lipinski, Malgorzata Ziemka-Nalecz, Malgorzata Frontczak-Baniewicz, Joanna Sypecka
Premature birth or complications during labor can cause temporary disruption of cerebral blood flow, often followed by long-term disturbances in brain development called hypoxic-ischemic (HI) encephalopathy. Diffuse damage to the white matter is the most frequently detected pathology in this condition. We hypothesized that oligodendrocyte progenitor cell (OPC) differentiation disturbed by mild neonatal asphyxia may affect the viability, maturation, and physiological functioning of oligodendrocytes. To address this issue, we studied the effect of temporal HI in the in vivo model in P7 rats with magnetic resonance imaging (MRI), microscopy techniques and biochemical analyses...
March 19, 2024: Brain Pathology
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