Luis C Farhat, Edoardo F Q Vattimo, Divya Ramakrishnan, Jessica L S Levine, Jessica A Johnson, Bekir B Artukoglu, Angeli Landeros-Weisenberger, Fernando R Asbahr, Sandra L Cepeda, Jonathan S Comer, Daniel Fatori, Martin E Franklin, Jennifer B Freeman, Daniel A Geller, Paul J Grant, Wayne K Goodman, Isobel Heyman, Tord Ivarsson, Fabian Lenhard, Adam B Lewin, Fenghua Li, Lisa J Merlo, Hamid Mohsenabadi, Tara S Peris, John Piacentini, Ana I Rosa-Alcázar, Àngel Rosa-Alcázar, Michelle Rozenman, Jeffrey J Sapyta, Eva Serlachius, Mohammad J Shabani, Roseli G Shavitt, Brent J Small, Gudmundur Skarphedinsson, Susan E Swedo, Per Hove Thomsen, Cynthia Turner, Bernhard Weidle, Euripedes C Miguel, Eric A Storch, David Mataix-Cols, Michael H Bloch
OBJECTIVE: A lack of universal definitions for response and remission in pediatric obsessive-compulsive disorder (OCD) has hampered the comparability of results across trials. To address this problem, we conducted an individual participant data diagnostic test accuracy meta-analysis to evaluate the discriminative ability of the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) in determining response and remission. We also aimed to generate empirically derived cutoffs on the CY-BOCS for these outcomes...
April 2022: Journal of the American Academy of Child and Adolescent Psychiatry