Y Roussel, D Raoult
Funding and gifts from the pharmaceutical industry have an influence on the decisions made by physicians and medical experts. In the context of the coronavirus disease 2019 epidemic, several treatments are available to treat patients infected with the virus. Some are protected by patents, such as remdesivir, others0020stare not, such as hydroxychloroquine. We wanted to observe the possible correlation between the fact, for an academic doctor in infectious diseases, of having benefited from funding by Gilead Sciences, producer of remdesivir, and the public positions taken by this doctor towards hydroxychloroquine...
November 2020: New Microbes and New Infections
M Million, P Gautret, P Colson, Y Roussel, G Dubourg, E Chabriere, S Honore, J-M Rolain, F Fenollar, P-E Fournier, J-C Lagier, P Parola, P Brouqui, D Raoult
In the context of the current coronavirus disease 2019 (COVID-19) pandemic, we conducted a meta-analysis on the effects of chloroquine derivatives in patients, based on unpublished and published reports available publicly on the internet as of 27 May 2020. The keywords 'hydroxychloroquine', 'chloroquine', 'coronavirus', 'COVID-19' and 'SARS-Cov-2' were used in the PubMed, Google Scholar and Google search engines without any restrictions as to date or language. Twenty studies were identified involving 105 040 patients (19 270 treated patients) from nine countries (Brazil, China, France, Iran, Saudi Arabia, South Korea, Spain and the USA)...
November 2020: New Microbes and New Infections
Jack Dowie, Mette Kjer Kaltoft, Vije Kumar Rajput
The questions 'What constitutes a good health care decision?', and, by extension, 'What constitutes good healthcare decision support?' continue to be asked. The most developed answers focus largely, often exclusively, on the quality of the 'deliberation' component as the determinant of the quality of the decision or decision aid. We argue that these answers and resulting aids reflect the preferences of healthcare professionals and aid developers and that these preferences are closely aligned with their interests...
September 4, 2020: Studies in Health Technology and Informatics
(no author information available yet)
No abstract text is available yet for this article.
October 1, 2020: JAMA Surgery
Peter T Morley, Dianne L Atkins, Judith C Finn, Ian Maconochie, Jerry P Nolan, Yacov Rabi, Eunice M Singletary, Tzong-Luen Wang, Michelle Welsford, Theresa M Olasveengen, Richard Aickin, John E Billi, Robert Greif, Eddy Lang, Mary E Mancini, William H Montgomery, Robert W Neumar, Gavin D Perkins, Jasmeet Soar, Myra H Wyckoff, Laurie J Morrison
No abstract text is available yet for this article.
October 20, 2020: Circulation
Peter Movilla, Jennifer Wang, Tammy Chen, Blanca Morales, Joyce Wang, Alexandria Williams, Himabindu Reddy, Jovana Tavcar, Megan Loring, Stephanie Morris, Keith Isaacson
STUDY QUESTION: Is there an association between endometrial thickness (EMT) measurement and clinical pregnancy rate among Asherman syndrome (AS) patients utilizing IVF and embryo transfer (ET)? SUMMARY ANSWER: EMT measurements may not be associated with successful clinical pregnancy among AS patients undergoing IVF. WHAT IS KNOWN ALREADY: Clinical pregnancy rate after IVF is significantly lower in patients with a thin endometrium, defined as a maximum EMT of <7 mm...
October 21, 2020: Human Reproduction
V Grzegorczyk-Martin, T Fréour, A De Bantel Finet, E Bonnet, M Merzouk, J Roset, V Roger, I Cédrin-Durnerin, R Wainer, C Avril, P Landais
STUDY QUESTION: How does a history of dramatic weight loss linked to bariatric surgery impact IVF outcomes? SUMMARY ANSWER: Women with a history of bariatric surgery who had undergone IVF had a comparable cumulative live birth rate (CLBR) to non-operated patients of the same BMI after the first IVF cycle. WHAT IS KNOWN ALREADY: In the current context of increasing prevalence of obesity in women of reproductive age, weight loss induced by bariatric surgery has been shown to improve spontaneous fertility in obese women...
October 21, 2020: Human Reproduction
David J Magid, Khalid Aziz, Adam Cheng, Mary Fran Hazinski, Amber V Hoover, Melissa Mahgoub, Ashish R Panchal, Comilla Sasson, Alexis A Topjian, Amber J Rodriguez, Aaron Donoghue, Katherine M Berg, Henry C Lee, Tia T Raymond, Eric J Lavonas
The 2020 American Heart Association (AHA) Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care is based on the extensive evidence evaluation performed in conjunction with the International Liaison Committee on Resuscitation. The Adult Basic and Advanced Life Support, Pediatric Basic and Advanced Life Support, Neonatal Life Support, Resuscitation Education Science, and Systems of Care Writing Groups drafted, reviewed, and approved recommendations, assigning to each recommendation a Class of Recommendation (ie, strength) and Level of Evidence (ie, quality)...
October 20, 2020: Circulation
Jane Barnsteiner, Maureen Shawn Kennedy, Annette Flanagin, Caroline Sietmann
PURPOSE: Concerns about conflicts of interest (COIs) in research and health care are well known, but recent reports of authors failing to disclose potential COIs in journal articles threatens the integrity of the scholarly literature. While many nursing journals have published editorials on this topic, review of nursing journal policies on and experiences with COIs has not been reported. The purposes of this study were to examine the extent to which nursing journals have COI policies and require disclosures by authors, peer reviewers, editorial board members, and editors who have a role in journal content decisions...
October 19, 2020: Journal of Nursing Scholarship
M Kroemer, A L Clairet, K Kabiche, A Bendjama, X Bertrand, S Limat, V Nerich
INTRODUCTION: Influenza vaccination coverage currently remains below the 75% recommended threshold by the World Health Organization. To correct this situation, experiments have been successively carried out in France to enable community pharmacists to vaccinate at-risk populations. In this context, a study was conducted with pharmacists from the French Franche-Comté Region to evaluate their positioning, needs and expectations regarding influenza vaccination at community pharmacies. MATERIALS AND METHODS: A survey was created and sent to licensed pharmacists in March of 2018...
October 16, 2020: Médecine et Maladies Infectieuses
J Lek, A A Vendrig, F G Schaafsma
BACKGROUND: Entrepreneurs may have to deal with different psychosocial risk factors than employees. Understanding relevant psychosocial risk factors for entrepreneurs is important for occupational health practice to develop effective measures to prevent work disability. This knowledge will be used to adjust the Work and Wellbeing Inventory an existing screening tool for employees. OBJECTIVE: The aim was to explore psychosocial risk factors and relevant personality traits to adjust and further develop the Work and Wellbeing Inventory to predict work disability for entrepreneurs...
October 12, 2020: Work: a Journal of Prevention, Assessment, and Rehabilitation
N Melamed, L Hiersch, A Aviram, S Keating, J C Kingdom
BACKGROUND: The value of using customized birthweight centiles to improve the diagnostic accuracy for fetal growth restriction (FGR), in comparison with using population-based charts, remains a matter of debate. One potential explanation for the conflicting data is that most studies used measures of perinatal mortality and morbidity as proxies for placenta-mediated FGR. However, many of these outcomes are not specific to placenta-mediated FGR, and may be confounded by other factors such as prematurity...
October 19, 2020: Ultrasound in Obstetrics & Gynecology
Narasimha M Beeraka, Surya P Sadhu, SubbaRao V Madhunapantula, Rajeswara Rao Pragada, Andrey A Svistunov, Vladimir N Nikolenko, Liudmila M Mikhaleva, Gjumrakch Aliev
Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2) induced Coronavirus Disease - 19 (COVID-19) cases have been increasing at an alarming rate (7.4 million positive cases as on June 11 2020), causing high mortality (4,17,956 deaths as on June 11 2020) and economic loss (a 3.2% shrink in global economy in 2020) across 212 countries globally. The clinical manifestations of this disease are pneumonia, lung injury, inflammation, and severe acute respiratory syndrome (SARS). Currently, there is no vaccine or effective pharmacological agents available for the prevention/treatment of SARS-CoV2 infections...
2020: Frontiers in Immunology
Geoff A Parker
The past half century has seen the development of the field of post-ejaculatory sexual selection, the sequel to sexual selection for mate-acquisition (pre-ejaculatory) described by Darwin. In richness and diversity of adaptations, post-ejaculatory selection rivals that of pre-ejaculatory sexual selection. Anisogamy-and hence two sexes-likely arose by primeval gamete competition, and sperm competition remains a major force maintaining high sperm numbers. The post-ejaculatory equivalent of male-male competition for matings, sperm competition was an intense ancestral form of sexual selection, typically weakening as mobility and internal fertilization developed in many taxa, when some expenditure became diverted into pre-ejaculatory competition...
December 7, 2020: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
Guiling Liang, Wei Xia, Yan Liang, Qian Zhu, Lujia Zou, Jian Zhang, Haowen Jiang
OBJECTIVE: To describe the treatments of a patient using the laparoscopic Davydov's method for Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and ureteral reimplantation for hydronephrosis and hydroureter. DESIGN: Surgical video article. A consent form from the patient was obtained as appropriate; the nature of the study did not necessitate ethics committee approval. There were no conflicts of interest. SETTING: University hospital. PATIENT(S): A 28-year-old woman who presented at our gynecology department with the symptoms of primary amenorrhea and difficult intercourse...
October 14, 2020: Fertility and Sterility
Brenda Maria Zoderer, Erich Tasser
In light of current trends of land abandonment across Europe, the rewilding of abandoned land is increasingly discussed as a future land management option. Since many of the regions affected by rewilding developments will be located in vicinity to densely populated areas, it is imperative to better understand public's attitudes towards an expansion of wilderness. Prior research on wilderness attitudes has typically been descriptive and rarely explored the underlying processes that lead to differences in wilderness attitudes...
October 15, 2020: Journal of Environmental Management
Stephen T Higgins
This Special Issue of Preventive Medicine (PM) is the 7th in a series on behavior change, health, and health disparities. This series focuses on personal behavior patterns, including substance use disorders, physical inactivity/obesity, and non-adherence with medical regimens, which are among the most important modifiable causes of chronic disease and premature death. This 7th issue includes 17 commentaries, reviews, and original empirical studies, 16 of which are devoted to current tobacco control and regulatory science research and policy, topics critically important to protecting the public health from the longstanding and devastating harms of tobacco use...
October 14, 2020: Preventive Medicine
Ho-Su Lee, Evy Lobbestael, Séverine Vermeire, João Sabino, Isabelle Cleynen
Inflammatory bowel disease and Parkinson's disease are chronic progressive disorders that mainly affect different organs: the gut and brain, respectively. Accumulating evidence has suggested a bidirectional link between gastrointestinal inflammation and neurodegeneration, in accordance with the concept of the 'gut-brain axis'. Moreover, recent population-based studies have shown that inflammatory bowel disease might increase the risk of Parkinson's disease. Although the precise mechanisms underlying gut-brain interactions remain elusive, some of the latest findings have begun to explain the link...
October 16, 2020: Gut
James Dunning, Raymond Butts, Noah Zacharko, Keith Fandry, Ian Young, Kenneth Wheeler, Jennell Day, César Fernández-de-Las-Peñas
BACKGROUND CONTEXT: Spinal manipulation, spinal mobilization and exercise are commonly used in individuals with cervicogenic headache (CH). Dry needling is being increasingly used in the management of CH. However, questions remain about the effectiveness of these therapies and how they compare to each other. PURPOSE: The present study aims to compare the combined effects of spinal manipulation and dry needling with spinal mobilization and exercise on pain and disability in individuals with CH...
October 13, 2020: Spine Journal: Official Journal of the North American Spine Society
Jiyin Zhou, Dan Liu
BACKGROUND: China's ethics committees alone are unable to meet the growing need for human participant protection. Several scandals in recent years indicate weaknesses in the protection of human participants in China. OBJECTIVES: The aim of the study is to summarize the status and problems of human research protection program in China and to explore its establishment proposals at national and hospital levels. RESEARCH DESIGN: To conduct literature retrieval, Chinese National Knowledge Infrastructure, Chinese Biomedical Document Database, and English databases Web of Science and PubMed were searched; laws, guidelines, and regulations were also searched on web by Google and Chinese search engine Baidu...
October 16, 2020: Nursing Ethics
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