Liyan Niu, Dingfa Liang, Qin Ling, Jing Zhang, Ziwen Li, Deju Zhang, Panpan Xia, Zicheng Zhu, Jitao Lin, Ao Shi, Jianyong Ma, Peng Yu, Xiao Liu
On 23rd July 2022, the World Health Organization (WHO) recognized the ongoing monkeypox outbreak as a public medical crisis. Monkeypox virus (MPV), the etiological agent of monkeypox, is a zoonotic, linear, double-stranded DNA virus. In 1970, the Democratic Republic of the Congo reported the first case of MPV infection. Human-to-human transmission can happen through sexual contact, inhaled droplets, or skin-to-skin contact. Once inoculated, the viruses multiply rapidly and spread into the bloodstream to cause viremia, which then affect multiple organs, including the skin, gastrointestinal tract, genitals, lungs, and liver...
2023: Frontiers in Immunology