Julian A Bustamante, Josue S Ceron, Ivan Thomas Gao, Hector A Ramirez, Milo V Aviles, Demsin Bet Adam, Jason R Brice, Rodrigo Cuellar, Eva Dockery, Miguel Karlo Jabagat, Donna Grace Karp, Joseph Kin-On Lau, Suling Li, Raymondo Lopez-Magaña, Rebecca R Moore, Bethany Kristi R Morin, Juliana Nzongo, Yasha Rezaeihaghighi, Joseph Sapienza-Martinez, Tuyet Thi Kim Tran, Zhenzhong Huang, Aaron J Duthoy, Melanie J Barnett, Sharon R Long, Joseph C Chen
Sinorhizobium meliloti is a model alpha-proteobacterium for investigating microbe-host interactions, in particular nitrogen-fixing rhizobium-legume symbioses. Successful infection requires complex coordination between compatible host and endosymbiont, including bacterial production of succinoglycan, also known as exopolysaccharide-I (EPS-I). In S. meliloti EPS-I production is controlled by the conserved ExoS-ChvI two-component system. Periplasmic ExoR associates with the ExoS histidine kinase and negatively regulates ChvI-dependent expression of exo genes, necessary for EPS-I synthesis...
October 23, 2023: PLoS Genetics