Richard B Pyles, Aaron L Miller, Randall J Urban, Melinda Sheffield-Moore, Traver J Wright, Carrie A Maxwell, Kathleen M Randolph, Christopher P Danesi, Kristen A McGovern, Jayson Vargas, Peyton Armstrong, Lisa Kreber, Giuliana Cumpa, Kevin Randall, Melissa Morrison, Brent E Masel
INTRODUCTION: Patients who suffer a traumatic brain injury (TBI) often experience chronic and sometimes debilitating sequelae. Recent reports have illustrated both acute and long-term dysbiosis of the gastrointestinal microbiome with significant alterations in composition and predicted functional consequences. METHODS: Working with participants from past research, metagenomic stability of the TBI- associated fecal microbiome (FMB) was evaluated by custom qPCR array comparing a fecal sample from 2015 to one collected in 2020...
2024: Frontiers in Molecular Neuroscience