Atakan Turgutkaya, İrfan Yavaşoğlu
No abstract text is available yet for this article.
July 2020: Indian Journal of Hematology & Blood Transfusion
Gisela Wegnelius, Katarina Bremme, Pelle Lindqvist
A program for care of women with immune thrombocytopenic purpura (ITP) with the recommendation to avoid treatment if platelets were >20 × 109/l during pregnancy, with the target level 100 × 109/l at delivery, was introduced. Treatment should be given with intravenous immunoglobulin (IVIG) or corticosteroids. Out of 75 pregnancies with ITP, 39 percent were treated and the treatment period was shorter with IVIG. Blood loss at delivery was similar as the reference population. Epidural analgesia was given in only 17 percent of the vaginal deliveries...
January 23, 2020: Läkartidningen
Atakan Turgutkaya, İrfan Yavaşoğlu
No abstract text is available yet for this article.
January 13, 2020: Journal of the Turkish German Gynecological Association
Büşra Betül Özmen Çapın, Meliha Çağla Sönmezer, Sema Tortop, Tuğçe Ünalan, Hatice Bölek, Sabri Engin Altıntop, Ahmet Çağkan İnkaya, Gökhan Metan, Sibel Ergüven
In spite of the fact that Plasmodium vivax is the leading causative agent of malaria in our country, imported malaria cases have been reported, recently. In this report, two malaria cases originated from sub-Saharan Africa, and their diagnostic and therapeutic approaches were aimed to be presented. First case, 45-year-old male, who has been working in Republic of Ghana, was admitted to Hacettepe University Hospitals Emergency Service with complaints of fever, sweating and shivering, after returning to Turkey...
October 2019: Mikrobiyoloji Bülteni
Ana Paula Rocha, Madalena Borges, Conceição Neves, João Farela Neves
We report a case of an 18-month-old boy with H factor deficiency with atypical presentation: recurrent acute otitis media and several maternal family members with autoimmune disorders (vitiligo, thyroiditis and immune trombocytopenia). Blood tests revealed low C3 and AH50, as well as low properdin and H factor. I factor was normal. CFH gene molecular test confirmed the H factor deficiency diagnosis. This child had none of the typical manifestations of this disorder, namely Neisseria meningitidis infection or renal disease (glomerulonephritis and atypical haemolytic uremic syndrome)...
February 28, 2019: Acta Médica Portuguesa
Guillermo Gutiérrez-Espíndola, Irazu Gallardo-Wong, Segundo Morán-Villota, Emma Álvarez-Pantoja, Susana Guerrero-Rivera, Jesús Medrano-Contreras, Juan Manuel Gallardo-Montoya, Luis A. Maillón-García
Background: Primary Immune Thrombocytopenia (TIP) is an autoimmune disease that accelerates the peripheral destruction of platelets and alters megakaryocytopoiesis. Helicobacter pylori infection and eradication has been associated with an increase in the platelet count in patients with IPT. The aim of this article is to evaluate the platelet response after H. pylori eradication in patients with chronic splenectomized IPT Methods: Between 2008 and 2009, adult patients with a diagnosis of chronic IPT, splenectomized; They were given breath test with carbon 13-labeled urea (PAU13C)...
2017: Revista Médica del Instituto Mexicano del Seguro Social
Alessandro Gasbarrini, Riccardo Ghermandi, Yunus Emre Akman, Marco Girolami, Stefano Boriani
OBJECTIVE: Percutaneous vertebroplasty with polymethylmethacrylate (PMMA) restores the stiffness and the strength of fractured vertebral bodies, but changes the pattern of the stress transfer. This effect may cause a secondary fracture of the adjacent vertebrae. Elastoplasty has emerged as a new technique to overcome this complication. The aim of this study is to retrospectively evaluate the clinical results of the elastoplasty procedure. MATERIALS AND METHODS: Thirthy nine patients (9 males, 30 females, 87 spinal levels) were clinically evaluated pre and postoperatively in terms of pain relief, leakage and silicone embolism...
May 2017: Acta Orthopaedica et Traumatologica Turcica
Carlo Caffarelli, Francesca Santamaria, Dora Di Mauro, Carla Mastrorilli, Virginia Mirra, Sergio Bernasconi
This review focuses key advances in different pediatric fields that were published in Italian Journal of Pediatrics and in international journals in 2015. Weaning studies continue to show promise for preventing food allergy. New diagnostic tools are available for identifying the allergic origin of allergic-like symptoms. Advances have been reported in obesity, short stature and autoimmune endocrine disorders. New molecules are offered to reduce weight gain and insulin-resistance in obese children. Regional investigations may provide suggestions for preventing short stature...
August 27, 2016: Italian Journal of Pediatrics
Dawid Szpecht, Dagmara Frydryszak, Norbert Miszczyk, Marta Szymankiewicz, Janusz Gadzinowski
INTRODUCTION: Intraventricular hemorrhage (IVH) is mostly documented in premature infants, and the younger the gestational age, the more often it occurs. IVH is very rarely reported in full-term neonates. CASE REPORT: Retrospective analysis was performed in 35939 full-term neonates, who were born in the Clinical Hospital of Gynecology and Obstetrics at the University of Medical Sciences in Poznań. Clinical data were retrieved from their medical records. We report a case series of 2 term newborns, who developed severe IVH grade 3 and 4 with no evidence of asphyxia, neuroinfection, TORCH infections, coagulation disorders and trombocytopenia, metabolic disorders, arteriovenous malformations, and selected genetic abnormalities (factor V Leiden 1601G > A polymorphism and MTHFR 677C > T; 1298A > C polymorphisms)...
December 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Hasan Üstün, Sabri Barutca, Esin Şanlı, Mine Çabuk, Mehmet Alakavuklar
CMF (cyclophosphamide, methotrexate and 5-fluorouracil) is one of the most commonly used chemotherapy (CT) regimens in breast cancer. To the best of our knowledge there are no published studies on the toxicity of this regimen in the existence of diabetes mellitus (DM), in the literature. We retrospectively analyzed the myelotoxicity of CMF CT after 40 adjuvant cycles of 18 diabetics, according to WHO toxicity scala. Leucopenia/granulocytopenia was the most prominent toxicity (observed in overall 30% of the cycles), but it was relatively mild (5% grade III and 2...
June 5, 2001: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
Michele Fiore, Lucio Trodella, Sergio Valeri, Domenico Borzomati, Barnaba Floreno, Edy Ippolito, Pasquale Trecca, Luca Eolo Trodella, Rolando Maria D'Angelillo, Sara Ramella, Roberto Coppola
BACKGROUND: Radio-chemotherapy is one of the steps of multidisciplinary management in locally advanced pancreatic cancer. The Epidermal Growth Factor Receptor (EGFR) plays an important role in the disease pathway. The purpose of this prospective study is to evaluate the feasibility and the efficacy of radiotherapy in combination with gemcitabine and EGFR targeting therapy for patients with locally advanced disease. MATERIALS AND METHODS: From November 2008 through January 2012, 34 patients were included in this study...
December 15, 2015: Radiation Oncology
Serap Ural, Figen Kaptan, Nurbanu Sezak, Sibel El, Bahar Örmen, Nesrin Türker, Tuna Demirdal, İlknur Vardar, Pınar Özkan Çayıröz, Fulya Çakalağaoğlu
Visceral leishmaniasis (VL, kala-azar) is a zoonotic infection caused by Leishmania species which are transmitted to humans by the bites of infected female phlebotomine sandflies. Leishmania infantum is the responsible species of VL in Aegean, Mediterranean, and Central Anatolia regions of Turkey mainly observed sporadically in pediatric age groups. The aim of this study was to evaluate the clinical and laboratory findings of adult patients with VL who were admitted to our hospital. A total of 10 patients (3 female, 7 male; age range: 18-67 years, mean age: 39...
October 2015: Mikrobiyoloji Bülteni
Jan Masopust, Jiří Charvát, Dana Mokrá, Ondřej Hloch, Jan Háša
Our report describes the case of patient with hypersensitive reaction regularly arising early after initiation of haemodialysis. This characteristic reaction with pletoric face coloration, bronchospasm, increase of blood pressure, anxiety and decrease of blood oxygen saturation at the consequence and central cyanosis was regularly present without dependence on type of dialysis membrane, drug premedication or prophylactic flushing haemodialysis system by isotonic natrium chloride solution. Low platelet value and trouble-free haemodialysis realized without heparin showed real cause of patients problem...
March 2015: Vnitr̆ní Lékar̆ství
Gianluca Villa, Maria Grazia D'Alfonso, Paola Di Maggio, Margherita Berardi, Cosimo Chelazzi, Anna Lucia Caldini, A Raffaele De Gaudio, Gian Franco Gensini, Serafina Valente
BACKGROUND: We report here a case of a woman affected by fever, weight loss, splenomegaly, and leucopenia associated with trombocytopenia, transferred to the intensive care unit with acute kidney injury and septic shock. METHODS: Patient was treated with high cut-off continuous veno-venous hemodialysis (HCO-CVVHD). RESULTS: During treatment, the patient experienced a stable improvement in the hemodynamic, pulmonary function and tissue perfusion parameters...
2014: Blood Purification
Pasquale Esposito, Carmelo Libetta, Ilaria Borettaz, Marisa Barone, Michele Canevari, Claudia Martinelli, Francesca Montagna, Salvatore Romeo, Elisa Margiotta, Marta Calatroni, Edoardo La Porta, Antonio Dal Canton
Heparin has remained the most commonly used anticoagulant in hemodialysis patients (HD). Its use is usually safe but, in some cases, important adverse effects can occur. Heparin-induced thrombocytopenia (HIT) is an immuno-mediated condition due to the formation of PF4/heparin/IgG complex leading to the activation of platelets and coagulative cascade. The consequent prothrombotic hypercoagulable state may cause venous or arterial thrombosis, skin gangrene and acute platelet activation syndrome. Clinical and laboratory findings may be suggestive for HIT, but formal diagnosis requires the demonstration of the presence of circulating antibodies...
May 2014: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
P Brychtová, M Procházka, V Lattová, M Lubušký, J Procházková, L Slavík, J Úlehlová, O Simetka
OBJECTIVE: The principal objective of the study is to compare results from the experimental group of pregnant women suffering from thrombocytopenia in pregnancy with results from the control group of pregnant women with normal physiologic blood platelet count. SETTING: Department of Obstetrics and Gynaecology of the Tomas Bata Regional Hospital Zlín, Obstetrics and Gynaecology Clinic, Haematology and Oncology Clinic of the Palacky University Teaching Hospital and Medical School in Olomouc, Obstetrics and Gynaecology Clinic of the Ostrava Teaching Hospital...
December 2013: Ceská Gynekologie
Cigdem Erten, Lutfiye Demir, Isil Somali, Ahmet Alacacioglu, Yuksel Kucukzeybek, Murat Akyol, Alper Can, Ahmet Dirican, Vedat Bayoglu, Mustafa Oktay Tarhan
BACKGROUND: To assess the efficacy and tolerability of Cisplatin plus Gemcitabine combination in patients with brain metastases (BM) from breast cancer (BC). MATERIALS AND METHODS: Eighteen BC patients with BM who were treated with Cisplatin plus Gemcitabine regimen between 2003-2011 were evaluated. RESULTS: A median of 6 cycles of this regimen were received, in fifteen patients (83.3%) as first-line chemotherapy, in 2 as second- line and in 1 as third-line after diagnosis of BM...
2013: Asian Pacific Journal of Cancer Prevention: APJCP
J J Korterink, B Boersma, M Schoorl, L Porcelijn, P C M Bartels
UNLABELLED: Ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia (PTCP) is the phenomenon of a false low platelet count reported by an automated haematology analyzer due to in vitro aggregation of platelets. This aggregation is due to the interaction between antibodies and EDTA-dependent crypt antigens on platelets. We observed a new born child whose mother was diagnosed with transient PTCP due to transplacental transmission of maternal immunoglobulin G antibodies during pregnancy...
July 2013: European Journal of Pediatrics
Yusuf Ziya Demiroğlu, Ilknur Kozanoğlu, Tuba Turunç, Ebru Kurşun, Hande Arslan
Plasmodium falciparum malaria is a type of malaria with high fatality rate despite optimal antimalarial treatment. Exchange transfusion (ET) is successfully used as a means of supportive therapy in severe P. falciparum malaria cases with hyperparasitemia. Herein, we present a case with hyperparasitemia, who received erythrocyte ET therapy due to lack of clinical response to antimalarial treatment. A 24-year-old male patient was admitted to our emergency clinic with the complaints of fever that persisted for 10 days, headache, nausea-vomiting, and impaired consciousness...
July 2012: Mikrobiyoloji Bülteni
Jirí Skultéty, M Novácková, T Binder, I Hadacová, P Salaj, L Rob
OBJECTIVE: Description of case of patient with rare thrombotic thrombocytopenic purpura in pregnancy. SUBJECT: Case report. SETTING: Department of Gynecology and Obstetrics, Charles University and University Hospital Motol, Prague. CONCLUSION: Thrombotic thrombocytopenic purpura (TTP) is a rare and substantial disorder characterized with combination of microangiopathic haemolytic anemia, consumption trombocytopenia and symptoms of organs dysfunction--especially kidneys and neurological deficiency...
August 2010: Ceská Gynekologie
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