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JOURNAL ARTICLE
Sanie E-Zehra Zaidi, Rahat Zaheer, Athanaisos Zovoilis, Tim A McAllister
The rapid increase of antimicrobial resistant bacteria in humans and livestock is concerning. Antimicrobials are essential for the treatment of disease in modern day medicine and their misuse in humans and food animals has contributed to an increase in the prevalence of antimicrobial resistant bacteria. Globally, antimicrobial resistance is recognized as an One-health problem affecting humans, animals and environment. Enterococcal species are gram positive bacteria that are widely distributed in nature. Their occurrence, prevalence and persistence across the One-health continuum make them an ideal candidate to study antimicrobial resistance from a One-health perspective...
May 2, 2024: Canadian Journal of Microbiology
#2
JOURNAL ARTICLE
Jiao-Qian Ying, Yu-Jiao Zhang, Yun-Qing Xia, Hao-di Ma, Tie Zhang, Ling Tu, Ai-Hui Zheng, Peng Gao, Wei-Hua Wang
BACKGROUND: To investigate the effectiveness of the intervention with critical value management and push short messaging service (SMS), and to determine improvement in the referral rate of patients with positive hepatitis C antibody (anti-HCV). METHODS: No intervention was done for patients with positive anti-HCV screening results from 1 January 2015 to 31 October 2021. Patients with positive anti-HCV results at our hospital from 1 November 2021 to 31 July 2022 were informed vide critical value management and push SMS...
December 2024: Annals of Medicine
#3
RANDOMIZED CONTROLLED TRIAL
Adam C Cunningham, Carley Prentice, Kimberly Peven, Aidan Wickham, Ryan Bamford, Tara Radovic, Anna Klepchukova, Maria Fomina, Katja Cunningham, Sarah Hill, Liisa Hantsoo, Jennifer Payne, Liudmila Zhaunova, Sonia Ponzo
BACKGROUND: Reproductive health literacy and menstrual health awareness play a crucial role in ensuring the health and well-being of women and people who menstruate. Further, awareness of one's own menstrual cycle patterns and associated symptoms can help individuals identify and manage conditions of the menstrual cycle such as premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). Digital health products, and specifically menstrual health apps, have the potential to effect positive change due to their scalability and ease of access...
May 2, 2024: JMIR MHealth and UHealth
#4
JOURNAL ARTICLE
Katsuyuki Yoshida, Soshi Takahashi, Ryota Kawai, Toshiharu Saito, Saori Hatachi, Ayumi Shintani, Hitoshi Sugawara, Shunichi Kumagai
OBJECTIVE: This study aimed to establish a screening model for differentiating anti-synthetase syndrome (ASS) from other antinuclear antibody (ANA)-associated rheumatic diseases (AARD) using a combination of cytoplasmic and non-cytoplasmic ANA (ncANA) patterns. METHODS: This retrospective observational study included patients with AARDs such as systemic lupus erythematosus (SLE), systemic sclerosis (SSc), Sjögren's syndrome (SS), mixed connective tissue disease (MCTD), and polymyositis/dermatomyositis (PM/DM) who underwent ANA screening between April 2012 and December 2021...
May 2, 2024: Rheumatology
#5
JOURNAL ARTICLE
Jiayu Shi, Guoye Lin, Rui Bao, Zhen Zhang, Jin Tang, Wenyue Chen, Hongjin Chen, Xinwei Zuo, Qianjin Feng, Shuguang Liu
OBJECTIVES: Currently, there is no reliable automated measurement method to study the changes in the condylar process after orthognathic surgery. Therefore, this study proposes an automated method to measure condylar changes in patients with skeletal class II malocclusion following surgical-orthodontic treatment. METHODS: Cone-beam computed tomography (CBCT) scans from 48 patients were segmented using the nnU-Net network for automated maxillary and mandibular delineation...
May 2, 2024: Dento Maxillo Facial Radiology
#6
JOURNAL ARTICLE
Cristofthe J Fernandes, Félix Netos, Patrício Costa
Few pandemic studies explored positive aspects of mental health and employed an intersectional perspective, which considers the concomitant action of different risk conditions. Our intersectional investigation aimed to identify possible mental illness and well-being differences between groups identified as psychologically vulnerable in the pandemic by the WHO (immigrants, minorities, and people with psychiatric diagnoses) and people without pre-existing risk factors while controlling for sociodemographic variables...
May 2, 2024: Revista Brasileira de Psiquiatria
#7
JOURNAL ARTICLE
Stephanie B Syc-Mazurek, Hannah Zhao-Fleming, Yong Guo, Nanthaya Tisavipat, John J Chen, Anastasia Zekeridou, Ioannis Kournoutas, Jacob J Orme, Matthew S Block, Claudia F Lucchinetti, Rafid Mustafa, Eoin P Flanagan
OBJECTIVES: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an autoimmune demyelinating disease rarely associated with malignancy. We report the clinical, MRI, immunopathology, and treatment response in a person with MOGAD and melanoma. METHODS: This is a case report of a person with a multidisciplinary evaluation at a tertiary referral center. RESULTS: A 52-year-old man presented with progressive encephalomyelitis that led to identification of metastatic melanoma...
July 2024: Neurology® Neuroimmunology & Neuroinflammation
#8
JOURNAL ARTICLE
Carolin Böing, Marta Di Fabrizio, Domenic Burger, John G J M Bol, Evelien Huisman, Annemieke J M Rozemuller, Wilma D J van de Berg, Henning Stahlberg, Amanda J Lewis
Multiple System Atrophy is characterized pathologically by the accumulation of alpha-synuclein (aSyn) into glial cytoplasmic inclusions (GCIs). The mechanism underlying the formation of GCIs is not well understood. In this study, correlative light and electron microscopy was employed to investigate aSyn pathology in the substantia nigra and putamen of post-mortem multiple system atrophy brain donors. Three distinct types of aSyn immuno-positive inclusions were identified in oligodendrocytes, neurons and dark cells presumed to be dark microglia...
May 2, 2024: Brain
#9
JOURNAL ARTICLE
Julian Theuriet, Marion Masingue, Anthony Behin, Ana Ferreiro, Guillaume Bassez, Pauline Jaubert, Oriana Tarabay, Frédéric Fer, Antoine Pegat, Françoise Bouhour, Juliette Svahn, Philippe Petiot, Laurentiu Jomir, Guy Chauplannaz, Catherine Cornut-Chauvinc, Véronique Manel, Emmanuelle Salort-Campana, Shahram Attarian, Etienne Fortanier, Annie Verschueren, Ludivine Kouton, Jean-Philippe Camdessanché, Céline Tard, Armelle Magot, Yann Péréon, Jean-Baptiste Noury, Marie-Christine Minot-Myhie, Maud Perie, Frederic Taithe, Yacine Farhat, Anne-Laure Millet, Pascal Cintas, Guilhem Solé, Marco Spinazzi, Florence Esselin, Dimitri Renard, Sabrina Sacconi, Andra Ezaru, Edoardo Malfatti, Martial Mallaret, Laurent Magy, Eva Diab, Philippe Merle, Maud Michaud, Maxime Fournier, Aleksandra Nadaj Pakleza, Jean-Baptiste Chanson, Claire Lefeuvre, Pascal Laforet, Pascale Richard, Damien Sternberg, Rocio-Nur Villar-Quiles, Tanya Stojkovic, Bruno Eymard
Congenital myasthenic syndromes (CMS) are clinically and genetically heterogeneous diseases caused by mutations affecting neuromuscular transmission. Even if the first symptoms mainly occur during childhood, adult neurologists must confront this challenging diagnosis and manage these patients throughout their adulthood. However, long-term follow-up data from large cohorts of CMS patients are lacking and the long-term prognosis of these patients is largely unknown. We report the clinical features, diagnostic difficulties, and long-term prognosis of a French nationwide cohort of 235 adult patients with genetically confirmed CMS followed in 23 specialized neuromuscular centres...
May 2, 2024: Brain
#10
JOURNAL ARTICLE
Zhaotan Gao, Ruiqi Jiang, Menghan Deng, Can Zhao, Zian Hong, Liyan Shang, Yawei Li, Liangqing Zhu, Jinzhong Zhang, Jian Zhang, Zhigao Hu
The processing of visual information occurs mainly in the retina, and the retinal preprocessing function greatly improves the transmission quality and efficiency of visual information. The artificial retina system provides a promising path to efficient image processing. Here, we propose graphene/InSe/h-BN heterogeneous structure, which exhibits negative and positive photoconductance effects by altering the strength of a single wavelength laser. Moreover, we present a modified theoretical model based on the power-dependent photoconductivity effect of laser: <mml:math xmlns:mml="https://www...
May 2, 2024: Advanced Materials
#11
JOURNAL ARTICLE
Masahide Saito, Koji Ueda, Hikaru Nemoto, Yoshiko Onishi, Hidekazu Suzuki, Toshihiro Suzuki, Naoki Sano, Takafumi Komiyama, Kan Marino, Hiroshi Onishi
BACKGROUND: Surface-guided radiotherapy (SGRT) is adopted by several institutions; however, reports on the phantoms used to assess the precision of the SGRT setup are limited. PURPOSE: The purpose of this study was to develop a phantom to verify the accuracy of the irradiation position during skin mark-less SGRT. METHODS: An acrylonitrile butadiene styrene (ABS) plastic cube phantom with a diameter of 150 mm on each side containing a dummy target of 15 mm and two types of body surface-shaped phantoms (breast/face shape) that could be attached to the cube phantom were fabricated...
May 2, 2024: Journal of Applied Clinical Medical Physics
#12
JOURNAL ARTICLE
Adam Barsouk, Omar Elghawy, Sara Stone, Aditi Singh
Selective RET inhibitors have shown promise in thyroid cancer (TC) and nonsmall cell lung cancer (NSCLC) harboring RET fusions on next-generation sequencing (NGS), although rarity of the rearrangement has led to limited data for certain tumor types, such as carcinoma of unknown primary. We present a 65-year-old female with no history of malignancy, smoking or radiation exposure, who was found to have an anterior mediastinum malignancy of unknown primary, with metastases to supraclavicular lymph nodes. Core biopsy of the mediastinum revealed poorly differentiated carcinoma, while a biopsy of the thyroid revealed atypia of indeterminate significance (Bethesda III)...
April 29, 2024: Anti-cancer Drugs
#13
JOURNAL ARTICLE
Gbenga Sunday Adeleye, E O Odesanmi, Kazeem O Ajeigbe, Tosan Omayone, Anthony Odetola, A Omolara Sobanke
Anaemia is a widespread health issue affecting young children and pregnant women, characterized by reduced red blood cells or haemoglobin levels. Coconut water, rich in nutrients such as L-arginine, iron, vitamin C, vitamin B6, folic acid and fatty acids, is believed to aid in blood formation (hematopoesis). The study aimed to examine the impact of coconut water on hematological indices and lipid profiles in rats with phenylhydrazine-induced anemia. 30 rats were divided into 5 groups: a normal control, phenylhydrazine untreated, coconut water (0...
December 31, 2023: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
#14
JOURNAL ARTICLE
Atim Antai, Imoh Ukoh, Bisong Sunday, Emem Edet, Martha Johnny
This study examines the effect of gestational administration of aqueous leaf extract of Jatropha tanjorensis (JT) on postpartum-like behavioural outcomes to delineate its possibility as a prophylactic, therapeutic agent in the treatment of postpartum symptoms. Inseminated female rats (120-150g) were grouped into two-control and JT group (n=10). Control received 20 ml/kg of distilled water and JT group received 500 mg/kg of JT orally once daily for 21 days in gestation. Non-pregnant rats were excluded from the study...
December 31, 2023: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
#15
JOURNAL ARTICLE
Y Yusha'u, Aisha Aminu Hanafi, Umar Muhammad Adam
Depression is a mental disorder characterized by depressive episodes, such as low mood, low self-esteem, feeling of guilt, and poor concentration. Depression has a high comorbidity with cognitive impairments. Studies have shown that cinnamon has anti-inflammatory antiviral, antihypertensive, antioxidant and anti-diabetic potentials. Therefore, the aim of the research was to assess the antidepressant effect of cinnamon on open-space forced swim-induced depression in mice. Twenty-five (25) Swiss albino mice were grouped into five groups (n=5)...
December 31, 2023: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
#16
(no author information available yet)
No abstract text is available yet for this article.
May 2, 2024: Nicotine & Tobacco Research
#17
JOURNAL ARTICLE
Janani Karunaratne, Sridhar Gona, Aaron George, Hugo J R Bonatti
Background: Lactococcus species are used to ferment milk to yogurt, cheese, and other products. The gram-positive coccus causes diseases in amphibia and fish and is a rare human pathogen. Patients and Methods: A 51-year-old male underwent laparoscopic cholecystectomy for acute and chronic calculous cholecystitis. Lactococcus lactis was isolated from pus from his gallbladder empyema. Results: Our institutional database was searched for other cases of Lactococcus spp. infections and four patients (2 males, 2 females; aged 51, 64, 78, and 80 years) were identified during a four-year period...
May 2, 2024: Surgical Infections
#18
JOURNAL ARTICLE
Alec Brown, Jacob L Steenwyk, Antonis Rokas
A. fumigatus is a deadly fungal pathogen, responsible for >400,000 infections/year and high mortality rates. A. fumigatus strains exhibit variation in infection-relevant traits, including in their virulence. However, most A. fumigatus protein-coding genes, including those that modulate its virulence, are shared between A. fumigatus strains and closely related non-pathogenic relatives. We hypothesized that A. fumigatus genes exhibit substantial genetic variation in the non-coding regions immediately upstream to the start codons of genes, which could reflect differences in gene regulation between strains...
May 2, 2024: G3: Genes—Genomes—Genetics
#19
JOURNAL ARTICLE
Karie Villanueva, Nisha Gupta, Tahera Alnaseri, Andrew L Da Lio, Jason Roostaeian, Michael DeLong
BACKGROUND: In 2021, the US Food and Drug Administration (FDA) issued a new checklist, labeling and rupture screening recommendations for breast implants to improve the decision-making process. OBJECTIVES: This study aims to understand the plastic surgeon's perspective on these changes and their perceived impact on clinical practice. METHODS: In September 2023, a 27 multiple-choice cross-sectional survey was distributed to 4,352 active members of the American Society of Plastic Surgeons to evaluate attitudes on the FDA's black box warning, informed decision checklist, and updated rupture screening recommendations...
May 2, 2024: Aesthetic Surgery Journal
#20
JOURNAL ARTICLE
Saji Maruthurkkara
OBJECTIVES: To develop and evaluate Cochlear™ Remote Assist (RA), a smartphone-based cochlear implant (CI) teleaudiology solution. The development phase aimed to identify the minimum features needed to remotely address most issues typically experienced by CI recipients. The clinical evaluation phase assessed ease of use, call clarity, system latency, and CI recipient feedback. DESIGN: The development phase involved mixed methods research with experienced CI clinicians...
May 2, 2024: International Journal of Audiology
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