keyword
https://read.qxmd.com/read/38626051/study-protocol-for-the-intraoperative-complications-assessment-and-reporting-with-universal-standards-icarus-global-cross-specialty-surveys-and-consensus
#1
JOURNAL ARTICLE
Giovanni E Cacciamani, Tamir Sholklapper, Michael B Eppler, Aref Sayegh, Lorenzo Storino Ramacciotti, Andre L Abreu, Rene Sotelo, Mihir M Desai, Inderbir S Gill
Annually, about 300 million surgeries lead to significant intraoperative adverse events (iAEs), impacting patients and surgeons. Their full extent is underestimated due to flawed assessment and reporting methods. Inconsistent adoption of new grading systems and a lack of standardization, along with litigation concerns, contribute to underreporting. Only half of relevant journals provide guidelines on reporting these events, with a lack of standards in surgical literature. To address these issues, the Intraoperative Complications Assessment and Reporting with Universal Standard (ICARUS) Global Surgical Collaboration was established in 2022...
2024: PloS One
https://read.qxmd.com/read/38625708/activity-of-the-sodium-leak-channel-maintains-the-excitability-of-paraventricular-thalamus-glutamatergic-neurons-to-resist-anesthetic-effects-of-sevoflurane-in-mice
#2
JOURNAL ARTICLE
Yujie Wu, Donghang Zhang, Jin Liu, Jingyao Jiang, Keyu Xie, Lin Wu, Yu Leng, Peng Liang, Tao Zhu, Cheng Zhou
BACKGROUND: Stimulation of the paraventricular thalamus has been found to enhance anesthesia recovery; however, the underlying molecular mechanism by which general anesthetics modulate paraventricular thalamus is unclear. Here, we aimed to test the hypothesis that the sodium leak channel (NALCN) maintains neuronal activity in paraventricular thalamus to resist anesthetic effects of sevoflurane in mice. METHOD: Chemogenetic and optogenetic manipulations, in vivo multiple-channel recordings, and electroencephalogram recordings were used to investigate the role of paraventricular thalamus neuronal activity in sevoflurane anesthesia...
April 16, 2024: Anesthesiology
https://read.qxmd.com/read/38625679/effects-of-positive-end-expiratory-pressure-on-pulmonary-perfusion-distribution-and-intrapulmonary-shunt-during-one-lung-ventilation-in-pigs-a-randomized-crossover-study
#3
JOURNAL ARTICLE
Jakob Wittenstein, Martin Scharffenberg, Jonathan Fröhlich, Carolin Rothmann, Xi Ran, Yingying Zhang, Yusen Chai, Xiuli Yang, Sabine Müller, Thea Koch, Robert Huhle, Marcelo Gama de Abreu
BACKGROUND: During one-lung ventilation (OLV), positive end-expiratory pressure (PEEP) can improve lung aeration, but might over-distend lung units and increase intrapulmonary shunt. We hypothesized that higher PEEP shifts pulmonary perfusion from the ventilated to the non-ventilated lung, resulting in a U-shaped relationship with intrapulmonary shunt during OLV. METHODS: In nine anesthetized female pigs, a thoracotomy was performed and intravenous lipopolysaccharide infused to mimic the inflammatory response of thoracic surgery...
April 16, 2024: Anesthesiology
https://read.qxmd.com/read/38624275/discovering-the-intriguing-properties-of-extrasynaptic-%C3%AE-aminobutyric-acid-type-a-receptors
#4
JOURNAL ARTICLE
Beverley A Orser
Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by α5 subunit-containing γ-aminobutyric acid type A receptors. By Caraiscos VB, Elliott EM, You-Ten KE, Cheng VY, Belelli D, Newell JG, Jackson MF, Lambert JJ, Rosahl TW, Wafford KA, MacDonald JF, Orser BA. Proc Natl Acad Sci U S A 2004; 101:3662-7. Reprinted with permission. In this Classic Paper Revisited, the author recounts the scientific journey leading to a report published in the Proceedings of the National Academy of Sciences (PNAS) and shares several personal stories from her formative years and "research truths" that she has learned along the way...
April 16, 2024: Anesthesiology
https://read.qxmd.com/read/38624227/perioperative-methadone-for-spine-surgery-a-scoping-review
#5
JOURNAL ARTICLE
Kieran P Nunn, Ahida A Velazquez, John F Bebawy, Kan Ma, Bruno Erick Sinedino, Akash Goel, Sergio M Pereira
Complex spine surgery is associated with significant acute postoperative pain. Methadone possesses pharmacological properties that make it an attractive analgesic modality for major surgeries. This scoping review aimed to summarize the evidence for the perioperative use of methadone in adults undergoing complex spine surgery. The review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). A search was performed using MEDLINE, CINAHL, Cochrane Library, Scopus, Embase, and Joanna Briggs between January 1946 and April 2023...
April 16, 2024: Journal of Neurosurgical Anesthesiology
https://read.qxmd.com/read/38623206/comprehensive-overview-of-the-anesthesiology-research-landscape-a-machine-learning-analysis-of-737-nih-funded-anesthesiology-primary-investigator-s-publication-trends
#6
JOURNAL ARTICLE
Marc Ghanem, Camilo Espinosa, Philip Chung, Momsen Reincke, Natasha Harrison, Thanaphong Phongpreecha, Sayane Shome, Geetha Saarunya, Eloise Berson, Tomin James, Feng Xie, Chi-Hung Shu, Debapriya Hazra, Samson Mataraso, Yeasul Kim, David Seong, Dipro Chakraborty, Manuel Studer, Lei Xue, Ivana Marić, Alan L Chang, Erico Tjoa, Brice Gaudillière, Vivianne L Tawfik, Sean Mackey, Nima Aghaeepour
BACKGROUND: Anesthesiology plays a crucial role in perioperative care, critical care, and pain management, impacting patient experiences and clinical outcomes. However, our understanding of the anesthesiology research landscape is limited. Accordingly, we initiated a data-driven analysis through topic modeling to uncover research trends, enabling informed decision-making and fostering progress within the field. METHODS: The easyPubMed R package was used to collect 32,300 PubMed abstracts spanning from 2000 to 2022...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38623142/mapping-the-landscape-simulation-centers-in-portugal
#7
JOURNAL ARTICLE
Bruno Miguel Silva, Gustavo Norte, Pedro Lito, Pedro Garcia
INTRODUCTION: Simulation-based training has emerged as a vital component of healthcare education. This study aims to characterize Portuguese simulation centers concerning their geographic distribution and key features, providing stakeholders with valuable insights to inform strategic decisions. METHODS: A cross-sectional survey-based study was conducted over two years (2021-2023) to investigate the geographical dispersion and characteristics of simulation centers in Portugal...
March 2024: Curēus
https://read.qxmd.com/read/38622510/the-efficacy-and-safety-of-perioperative-glucocorticoid-for-total-knee-arthroplasty-a-systematic-review-and-meta-analysis
#8
JOURNAL ARTICLE
Fangyan Liu, Mei Duan, Huiqun Fu, Tianlong Wang
BACKGROUND: An increasing number of individuals undergo total knee arthroplasty (TKA), which can result in pain, limited motor function and adverse complications such as infection, nausea and vomiting. Glucocorticoids have been shown anti-inflammatory and antiemetic effects, but can also elevate blood glucose levels and increase the risk of wound infection. Thus, it is essential to investigate the efficacy and safety of glucocorticoid usage in TKA. METHOD: A comprehensive systematic search of PubMed, Medline, EMBASE, Cochrane databases, to identify relevant randomized controlled trials (RCTs) of glucocorticoid application in TKA...
April 15, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38622469/efficacy-of-different-routes-of-acetaminophen-administration-for-postoperative-pain-in-children-a-systematic-review-and-network-meta-analysis
#9
JOURNAL ARTICLE
Danilo Osorio, Diana Maldonado, Koen Rijs, Caroline van der Marel, Markus Klimek, Jose A Calvache
PURPOSE: Acetaminophen is the most common drug used to treat acute pain in the pediatric population, given its wide safety margin, low cost, and multiple routes for administration. We sought to determine the most efficacious route of acetaminophen administration for postoperative acute pain relief in the pediatric surgical population. METHODS: We conducted a systematic review of randomized controlled trials (RCTs) that included children aged between 30 days and 17 yr who underwent any type of surgical procedure and that evaluated the analgesic efficacy of different routes of administration of acetaminophen for the treatment of postoperative pain...
April 15, 2024: Canadian Journal of Anaesthesia
https://read.qxmd.com/read/38622308/current-management-of-surgical-neonates-is-it-optimal-or-do-we-need-to-improve-a-national-survey-of-the-italian-society-of-neonatology
#10
JOURNAL ARTICLE
Simonetta Costa, Irma Capolupo, Luca Bonadies, Michele Quercia, Maria Pasqua Betta, Sara Gombos, Costanza Tognon, Giacomo Cavallaro, Stefania Sgrò, Roberta Pastorino, Denise Pires Marafon, Andrea Dotta, Giovanni Vento
PURPOSE: Few guidelines exist for the perioperative management (PM) of neonates with surgical conditions (SC). This study examined the current neonatal PM in Italy. METHODS: We invited 51 neonatal intensive care units with pediatric surgery in their institution to participate in a web-based survey. The themes included (1) the involvement of the neonatologist during the PM; (2) the spread of bedside surgery (BS); (3) the critical issues concerning the neonatal PM in operating rooms (OR) and the actions aimed at improving the PM...
April 16, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38621289/self-citation-patterns-of-anesthesiology-journals-indexed-in-the-journal-citation-reports
#11
JOURNAL ARTICLE
Burhan Dost, Alessandro De Cassai
No abstract text is available yet for this article.
May 1, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38621288/letter-regarding-the-potential-improper-use-of-the-individual-typology-angle-in-the-context-of-disparate-bias-in-pulse-oximetry
#12
JOURNAL ARTICLE
Wim Verkruysse, Michael B Jaffe
No abstract text is available yet for this article.
May 1, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38621287/physicochemical-stability-of-ketamine-after-reconstitution-for-injection-a-scoping-review
#13
JOURNAL ARTICLE
Mohammed Adinoyi Usman, Orshio Uga Donald, Dalhat Salahu, Irene Irenosen Akhideno
No abstract text is available yet for this article.
May 1, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38621286/in-response
#14
JOURNAL ARTICLE
Alexis L Cull, Mercede N Erickson
No abstract text is available yet for this article.
May 1, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38621285/neostigmine-and-postoperative-cognitive-dysfunction-in-the-elderly-teaching-an-old-dog-a-new-trick
#15
JOURNAL ARTICLE
Hisako Okada, Amir L Butt, Pamela R Roberts, Kenichi A Tanaka
No abstract text is available yet for this article.
May 1, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38621284/postpartum-opioid-prescribing-and-persistent-use-in-western-countries
#16
JOURNAL ARTICLE
Jashvant Poeran, Chang H Park
No abstract text is available yet for this article.
May 1, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38621283/pro-con-debate-universal-versus-selective-continuous-monitoring-of-postoperative-patients
#17
JOURNAL ARTICLE
George T Blike, Susan P McGrath, Michelle A Ochs Kinney, Bhargavi Gali
In this Pro-Con commentary article, we discuss use of continuous physiologic monitoring for clinical deterioration, specifically respiratory depression in the postoperative population. The Pro position advocates for 24/7 continuous surveillance monitoring of all patients starting in the postanesthesia care unit until discharge from the hospital. The strongest arguments for universal monitoring relate to inadequate assessment and algorithms for patient risk. We argue that the need for hospitalization in and of itself is a sufficient predictor of an individual's risk for unexpected respiratory deterioration...
May 1, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38621282/enhanced-postoperative-monitoring-mixed-realities-and-new-frontiers
#18
JOURNAL ARTICLE
Satya Krishna Ramachandran
No abstract text is available yet for this article.
May 1, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38621281/artificial-intelligence-perceptions-and-attitudes
#19
JOURNAL ARTICLE
Naveen Nathan
No abstract text is available yet for this article.
May 1, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38621280/rediscovering-renin
#20
JOURNAL ARTICLE
Naveen Nathan
No abstract text is available yet for this article.
May 1, 2024: Anesthesia and Analgesia
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