keyword
https://read.qxmd.com/read/38547233/ethical-care-in-patients-with-covid-19-a-grounded-theory
#41
JOURNAL ARTICLE
Hamideh Azimi, Rafat Rezapour-Nasrabad, Fariba Borhani, Akram Sadat Sadat Hoseini, Fariba Bolourchifard
BACKGROUND: Providing ethical care during the Covid-19 pandemic has become an inevitable challenge due to facing limitations such as fear of contracting the disease, lack of equipment and emergence of ethical conflicts; So that there is no clear picture of how to provide ethical care for patients with Covid-19. The study aimed to explain the ethical care process of patients with Covid-19. METHOD: This qualitative study was conducted in 2021-2023 using the grounded theory research method...
2024: PloS One
https://read.qxmd.com/read/38544204/from-movements-to-metrics-evaluating-explainable-ai-methods-in-skeleton-based-human-activity-recognition
#42
JOURNAL ARTICLE
Kimji N Pellano, Inga Strümke, Espen A F Ihlen
The advancement of deep learning in human activity recognition (HAR) using 3D skeleton data is critical for applications in healthcare, security, sports, and human-computer interaction. This paper tackles a well-known gap in the field, which is the lack of testing in the applicability and reliability of XAI evaluation metrics in the skeleton-based HAR domain. We have tested established XAI metrics, namely faithfulness and stability on Class Activation Mapping (CAM) and Gradient-weighted Class Activation Mapping (Grad-CAM) to address this problem...
March 18, 2024: Sensors
https://read.qxmd.com/read/38543288/development-of-a-semi-mechanistic-modeling-framework-for-wet-bead-milling-of-pharmaceutical-nanosuspensions
#43
JOURNAL ARTICLE
Donald J Clancy, Gulenay Guner, Sayantan Chattoraj, Helen Yao, M Connor Faith, Zahra Salahshoor, Kailey N Martin, Ecevit Bilgili
This study aimed to develop a practical semi-mechanistic modeling framework to predict particle size evolution during wet bead milling of pharmaceutical nanosuspensions over a wide range of process conditions and milling scales. The model incorporates process parameters, formulation parameters, and equipment-specific parameters such as rotor speed, bead type, bead size, bead loading, active pharmaceutical ingredient (API) mass, temperature, API loading, maximum bead volume, blade diameter, distance between blade and wall, and an efficiency parameter...
March 13, 2024: Pharmaceutics
https://read.qxmd.com/read/38540515/narrative-forewarnings-a-qualitative-analysis-of-the-themes-preceding-disorganized-speech-in-schizophrenia
#44
JOURNAL ARTICLE
Robert J Bettis, Laura A Faith, Ashlynn M Beard, Brailee A Whan, Ceouna M Hegwood, Mahogany A Monette, Evan J Myers, Imani S Linton, Bethany L Leonhardt, Michelle P Salyers, Kyle S Minor
Disorganized speech is a critical barrier to recovery in schizophrenia, with profound negative impacts on one's ability to engage with the world. Despite the limited efficacy of existing treatments in addressing disorganization, a qualitative analysis of what leads to disorganization in patient narratives has been lacking. This study addresses this gap through inductive thematic analysis of 30 narrative interviews with individuals with schizophrenia, matched based on whether Formal Thought Disorder (FTD) is present...
March 6, 2024: Behavioral Sciences
https://read.qxmd.com/read/38540242/co-culture-models-key-players-in-in-vitro-neurotoxicity-neurodegeneration-and-bbb-modeling-studies
#45
REVIEW
Ana Rita Monteiro, Daniel José Barbosa, Fernando Remião, Renata Silva
The biological barriers existing in the human body separate the blood circulation from the interstitial fluid in tissues. The blood-brain barrier (BBB) isolates the central nervous system from the bloodstream, presenting a dual role: the protection of the human brain against potentially toxic/harmful substances coming from the blood, while providing nutrients to the brain and removing metabolites. In terms of architectural features, the presence of junctional proteins (that restrict the paracellular transport) and the existence of efflux transporters at the BBB are the two major in vivo characteristics that increase the difficulty in creating an ideal in vitro model for drug permeability studies and neurotoxicity assessments...
March 12, 2024: Biomedicines
https://read.qxmd.com/read/38533343/exploration-of-the-motivational-factors-that-influence-the-maintenance-of-health
#46
JOURNAL ARTICLE
Misha Choudry, Latha Ganti
OBJECTIVE: This study aims to identify motivators influencing individuals' commitment to maintaining positive health trajectories across different demographics. The primary objective is to leverage this knowledge to enhance patient-physician relationships and improve the quality of care. METHODS: A web-based survey collected data from 204 randomly selected participants aged 16 and older. The survey assessed participants' self-rated health, health-related habits, and motivators for a healthy lifestyle...
2024: Health Psychology Research
https://read.qxmd.com/read/38528275/barriers-and-facilitators-to-24-month-maintenance-of-the-faith-activity-and-nutrition-program-in-the-u-s
#47
JOURNAL ARTICLE
Kelsey R Day, John A Bernhart, Sara Wilcox
Little is known about the barriers and facilitators to organizational maintenance of faith-based health promotion programs. This study used qualitative data (collected from 2016-2019) from pastors (n = 81) and program coordinators (n = 103) to identify barriers and facilitators to 24-month maintenance of a faith-based physical activity (PA) and healthy eating (HE) intervention in South Carolina. Barriers differed for PA versus HE: resistance to change impeded HE while church characteristics tended to impede PA...
March 25, 2024: Journal of Religion and Health
https://read.qxmd.com/read/38527203/climate-sustainability-through-a-dynamic-duo-green-hydrogen-and-crypto-driving-energy-transition-and-decarbonization
#48
JOURNAL ARTICLE
Apoorv Lal, Fengqi You
Climate change persists as a pressing global issue due to high greenhouse gas emissions from fossil fuel-based energy sources. A transition to a greener energy matrix combined with carbon offsetting is imperative to mitigate the rate at which global temperature ascends. While countries have deployed faith in green hydrogen to accelerate worldwide decarbonization efforts, the concurrent rise of blockchain-operated crypto-applications, such as bitcoin, has exacerbated climate change concerns. In this study, we propose technological solutions that combine the green hydrogen infrastructure with bitcoin mining operations to catalyze environmental and socioeconomic sustainability in climate change mitigation strategies...
April 2, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38525972/organoid-based-personalized-medicine-from-tumor-outcome-prediction-to-autologous-transplantation
#49
JOURNAL ARTICLE
Abel Soto-Gamez, Jennifer P Gunawan, Lara Barazzuol, Sarah Pringle, Robert P Coppes
Inter-individual variation largely influences disease susceptibility, as well as response to therapy. In a clinical context, the optimal treatment of a disease should consider inter-individual variation and formulate tailored decisions at an individual level. In recent years, emerging organoid technologies promise to capture part of an individual's phenotypic variability and prove helpful in providing clinically relevant molecular insights. Organoids are stem cell-derived three-dimensional models that contain multiple cell types that can self-organize and give rise to complex structures mimicking the organization and functionality of the tissue of origin...
March 25, 2024: Stem Cells
https://read.qxmd.com/read/38525347/forgone-healthcare-for-medically-vulnerable-groups-during-the-pandemic-era-experiences-of-family-caregivers-of-young-adults-with-substance-use-disorders-in-zambia
#50
JOURNAL ARTICLE
Ireen Manase Kabembo
INTRODUCTION: Scholars worldwide have defined the COVID-19 pandemic as a mass-disabling event of our time. The situation is grave for families experiencing financial hurdles while caring for young adults in recovery from addiction problems. METHODS: Using semi-structured interviews with 30 purposively selected family caregivers (FCGs) of young adults with substance use disorders (SUDs) in Lusaka, Zambia, this study reveals several factors influencing forgone healthcare for this medically vulnerable group...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38517933/no-evidence-for-adult-smartphone-use-affecting-attribution-of-communicative-intention-in-toddlers-online-imitation-study-using-the-sock-ball-task
#51
JOURNAL ARTICLE
Solveig Flatebø, Gabriella Óturai, Mikołaj Hernik
Adults infer others' communicative intentions, or lack thereof, from various types of information. Young children may be initially limited to attributions based on a small set of ostensive signals. It is unknown when richer pragmatic inferences about communicative intentions emerge in development. We sought novel type of evidence for such inferences in 17-to-19-month-olds. We hypothesized that toddlers recognize adults' smartphone use in face-to-face interactions as incongruous with ostension and would rely on this interpretation when inferring the communicative intention of a model in a new imitation task conducted entirely online, dubbed the Sock Ball Task...
2024: PloS One
https://read.qxmd.com/read/38517823/a-hybrid-denoising-approach-for-ppg-signals-utilizing-variational-mode-decomposition-and-improved-wavelet-thresholding
#52
JOURNAL ARTICLE
Qinghua Hu, Min Li, Linwen Jiang, Mei Liu
BACKGROUND: Photoplethysmography (PPG) signals are sensitive to motion-induced interference, leading to the emergence of motion artifacts (MA) and baseline drift, which significantly affect the accuracy of PPG measurements. OBJECTIVE: The objective of our study is to effectively eliminate baseline drift and high-frequency noise from PPG signals, ensuring that the signal's critical frequency components remain within the range of 1 ∼ 10 Hz. METHODS: This paper introduces a novel hybrid denoising method for PPG signals, integrating Variational Mode Decomposition (VMD) with an improved wavelet threshold function...
February 20, 2024: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://read.qxmd.com/read/38514511/associations-between-religiosity-and-medical-mistrust-an-age-stratified-analysis-of-survey-data-from-black-adults-in-chicago
#53
JOURNAL ARTICLE
Jacquelyn Jacobs, Jennifer L Walsh, Jesus Valencia, Wayne DiFranceisco, Jana L Hirschtick, Bijou R Hunt, Katherine G Quinn, Maureen R Benjamins
Medical mistrust is associated with poor health outcomes, ineffective disease management, lower utilization of preventive care, and lack of engagement in research. Mistrust of healthcare systems, providers, and institutions may be driven by previous negative experiences and discrimination, especially among communities of color, but religiosity may also influence the degree to which individuals develop trust with the healthcare system. The Black community has a particularly deep history of strong religious communities, and has been shown to have a stronger relationship with religion than any other racial or ethnic group...
March 21, 2024: Journal of Racial and Ethnic Health Disparities
https://read.qxmd.com/read/38513017/efficient-formation-of-single-copy-human-artificial-chromosomes
#54
JOURNAL ARTICLE
Craig W Gambogi, Gabriel J Birchak, Elie Mer, David M Brown, George Yankson, Kathryn Kixmoeller, Janardan N Gavade, Josh L Espinoza, Prakriti Kashyap, Chris L Dupont, Glennis A Logsdon, Patrick Heun, John I Glass, Ben E Black
Large DNA assembly methodologies underlie milestone achievements in synthetic prokaryotic and budding yeast chromosomes. While budding yeast control chromosome inheritance through ~125-base pair DNA sequence-defined centromeres, mammals and many other eukaryotes use large, epigenetic centromeres. Harnessing centromere epigenetics permits human artificial chromosome (HAC) formation but is not sufficient to avoid rampant multimerization of the initial DNA molecule upon introduction to cells. We describe an approach that efficiently forms single-copy HACs...
March 22, 2024: Science
https://read.qxmd.com/read/38511920/faith-and-science-sacred-decision-making-in-cancer-care
#55
JOURNAL ARTICLE
Joni L Watson
Many people view health, wellness, and illness through a lens of religion and spirituality (R&S), modern science, and culture. Faith and science are not dichotomous in health care; they are complementary and even intercon.
March 15, 2024: Clinical Journal of Oncology Nursing
https://read.qxmd.com/read/38510421/-we-forgot-about-the-donkeys-an-institutional-analysis-of-the-shift-in-animal-welfare-from-direct-implementation-towards-advocacy-based-programming
#56
JOURNAL ARTICLE
Emily Haddy, Leanne Proops, Faith Burden, Zoe Raw, Juliane Kaminski, Julia Brown
Shifts from direct implementation to advocacy-based programming have been documented across many non-governmental organisation (NGO) sectors, including animal welfare. Semi-structured interviews with 32 staff from different positions within animal welfare NGOs explored recent programming changes. Maintaining a balance between direct implementation and advocacy-based activities emerged as a strong theme. The findings suggest that risks are associated with both the direct implementation status quo and transitioning to an advocacy-based focus...
2024: Animal Welfare
https://read.qxmd.com/read/38509458/promoting-meaningful-activities-by-occupational-therapy-in-elderly-care-in-belgium-the-promote-intervention
#57
JOURNAL ARTICLE
Leen De Coninck, Anja Declercq, Leen Bouckaert, Carola Döpp, Maud J L Graff, Bert Aertgeerts
BACKGROUND: Older people want to age in place. Despite advancing functional limitations and their desire of aging in place, they are not always faithful to therapy that maintains independence and promotes safety. Occupational therapists can facilitate aging in place. Occupational therapy is defined as the therapeutic use of everyday life occupations with persons, groups, or populations for the purpose of enhancing or enabling participation. AIM: To describe the content a high-adherence-to-therapy and evidence-based occupational therapy intervention to optimize functional performance and social participation of home-based physically frail older adults and wellbeing of their informal caregiver, and the research activities undertaken to design this intervention...
March 20, 2024: BMC Geriatrics
https://read.qxmd.com/read/38508992/the-effect-of-observing-religious-or-faith-based-fasting-on-cardiovascular-disease-risk-factors-a-systematic-review-and-meta-analysis
#58
JOURNAL ARTICLE
Negin Gholampoor, Amir Hossien Sharif, Duane Mellor
AIMS: Cardiovascular diseases (CVD) are the leading cause of death worldwide. Fasting is common in many religions and is associated with health benefits. This systematic review to compares the impact of different religious fasting practices, on risk of cardiometabolic diseases. DATA SYNTHESIS: The search covered five databases following PRISMA guidelines to identify papers published in English from inception to March 2023 (updated January 2024). Inclusion criteria were healthy adults in observational studies, who engaged in religious fasting practices, studies were included where data on matched non-fasting individuals was available...
February 16, 2024: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://read.qxmd.com/read/38505761/the-importance-of-community-based-and-community-partnered-covid-19-testing-for-reducing-disparities-among-african-american-populations
#59
REVIEW
Chavon Hamilton-Burgess, Jannette Berkley-Patton, Jenifer Allsworth, Carole Bowe Thompson, Frank E Thompson, Tacia Burgin, Eric D Williams, Kathryn P Derose
BACKGROUND: Health inequalities in African American communities have been further exacerbated by COVID-19. Public health departments and other safety-net providers across the United States have partnered with community-based organizations to address barriers to COVID-19 testing in disproportionately impacted communities. This narrative review summarizes lessons learned from published examples of these community-based COVID-19 testing efforts. METHODS: We searched online databases for peer-reviewed articles on community-based COVID-19 testing interventions in the United States aimed at increasing COVID-19 testing among African American populations...
2024: Health Equity
https://read.qxmd.com/read/38504526/sex-workers-in-canada-face-unequal-access-to-healthcare-a-systems-thinking-approach
#60
JOURNAL ARTICLE
Kaitlyn Squires
OBJECTIVES: Despite Canada's universal health system, sex workers across the country face an alarmingly high number of barriers when they seek to healthcare services. This has resulted in unmet healthcare needs and substantially poorer health outcomes than the general Canadian population. The objective of this study was to use a systems thinking approach to gain an in-depth understanding of the barriers sex workers face and how access could be improved. METHODS: The analysis was conducted using a systems thinking methodology, which incorporates systems tools and inquiry processes...
2024: Journal of Primary Care & Community Health
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