keyword
https://read.qxmd.com/read/38644983/anorectal-infections-in-neutropenic-leukemia-patients-a-common-clinical-challenge
#1
REVIEW
Rodrick Babakhanlou, Farhad Ravandi-Kashani, Angel G Hita, Dimitrios P Kontoyiannis
Anorectal infections in neutropenic leukemia patients are a significant and potentially life-threatening complication. The pathogenesis of this condition is not entirely understood and believed to be multifactorial, including mucosal injury as a result of cytotoxic drugs, profound neutropenia and impaired host defense. Establishing an early diagnosis is key and often made clinically on the basis of signs and symptoms, but also from imaging studies demonstrating perianal inflammation or fluid collection. The management of anorectal infections in neutropenic leukemia patients is not straightforward, as there are no well-conducted studies on this entity...
April 2024: Journal of Hematology (Brossard, Quebec)
https://read.qxmd.com/read/38580791/current-update-on-the-role-of-endoanal-ultrasound-a-primer-for-radiologists
#2
REVIEW
Shruti Kumar, Ranjit K Chaudhary, Samir S Shah, Devendra Kumar, Pankaj Nepal, Vijayanadh Ojili
Endoanal ultrasound (EAUS) is a valuable imaging modality for the evaluation of anal and perianal pathologies. It provides detailed information about the anatomy and physiology of the anorectal region and has been used in pre-and post-operative settings of anorectal pathologies. EAUS is not only useful in the evaluation of benign pathologies but also in loco-regional staging of anal and rectal tumors. EAUS has several advantages over MRI, including reduced cost, better patient tolerance, and improved scope of application in patients with contraindications to MRI...
April 5, 2024: Abdominal Radiology
https://read.qxmd.com/read/38520491/research-progress-of-robot-and-laparoscope-in-postoperative-complications-of-rectal-cancer
#3
REVIEW
Jiming Lian, Jinbiao Li, Cong Liu, BaoDong Luan, Yanmin Miao
Rectal cancer is one of the most common malignant tumours worldwide, and it is also one of the major diseases that seriously threatens human life and health. At present, the main treatment for rectal cancer is still surgical treatment. The surgical methods have been rapidly developed from the previous open surgery to the current minimally invasive surgery. At present, there are two main minimally invasive surgeries: robotic surgery and laparoscopic surgery. Due to the particularity of rectal cancer surgery, more and more studies have shown that robotic rectal cancer surgery has more advantages than laparoscopic rectal cancer surgery...
March 23, 2024: Journal of Robotic Surgery
https://read.qxmd.com/read/38511911/perianal-injury-prevention-in-patients-with-leukemia
#4
JOURNAL ARTICLE
Cindy Paredes, Katie Reed, LaTarvia Moore, Jeannine M Brant
BACKGROUND: Perianal injuries in adults with hematologic malignancies can result in sepsis or death. Patients on a 36-bed acute care oncology unit experienced increased perianal injuries from 2018 to 2021 based on a chart review, which revealed that 24 patients with leukemia, all of whom had received cytarabine, developed perianal injuries. OBJECTIVES: This study examined whether a nurse-led educational intervention would decrease perianal injuries. METHODS: A survey examined baseline nurse knowledge on perianal injuries...
March 15, 2024: Clinical Journal of Oncology Nursing
https://read.qxmd.com/read/38481157/clinical-features-of-inflammatory-bowel-disease-unclassified-a-case-control-study
#5
JOURNAL ARTICLE
Yupei Shao, Yixiao Zhao, Hong Lv, Pengguang Yan, Hong Yang, Jingnan Li, Ji Li, Jiaming Qian
BACKGROUND: Approximately 10-15% of inflammatory bowel disease (IBD) patients with overlapping features of ulcerative colitis (UC) and Crohn's disease (CD) are termed as inflammatory bowel disease unclassified (IBDU). This study aimed to describe the clinical features of IBDU and evaluate the potential associated factors of reclassification. METHODS: The clinical data of 37 IBDU patients were retrospectively analyzed from November 2012 to November 2020. 74 UC and 74 CD patients were randomly selected and age- and sex-matched with the 37 IBDU patients...
March 13, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38476336/fournier-s-gangrene-due-to-rectal-cancer-a-case-report
#6
Sen Hou, Baosen Cheng, Kai Shen, Zhidong Gao, Fan Liu, Yingjiang Ye
Fournier's gangrene (FG) is an extremely rare necrotizing fasciitis that is insidious, rapidly spreading and life-threatening. FGs due to rectal cancer occur rarely and there is a lack of clinical reference. In the present study, a severe FG due to rectal cancer perforation was described and the features of this rare disease were summarized with a literature review. A 57-year-old man was admitted because of rectal cancer-induced FG. The patient was misdiagnosed with extensive perianal abscess until the intraoperative biopsy confirmed that rectal cancer was the culprit...
April 2024: Molecular and Clinical Oncology
https://read.qxmd.com/read/38448866/sciatica-caused-by-spinal-epidural-abscess-as-the-initial-clinical-presentation-of-colon-cancer-a-rare-case-report-and-review-of-literature
#7
JOURNAL ARTICLE
Kuan-Yu Lu, Wei-En Tung, Chang-Jung Chiang, Yueh-Ying Hsieh, Chia-Hsien Chen, Mei-Hui Lee, Min-Hsuan Yen, Po-Wen Lu, Lien-Chen Wu
BACKGROUND: Colorectal cancer is one of the most frequently diagnosed forms of cancer, and it is associated with several common symptoms and signs such as rectal bleeding, altered bowel habits, abdominal pain, anemia, and unintentional weight loss. Sciatica, a debilitating condition in which the patient experiences paresthesia and pain in the dermatome of associated lumbosacral nerve roots or sciatic nerve distribution, is not considered one of these. Here we present a case of colorectal cancer manifesting symptoms of sciatica alone...
March 6, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38428446/aluminum-potassium-sulfate-and-tannic-acid-alta-sclerotherapy-for-hemorrhoidal-disease-a-systematic-review-and-meta-analysis
#8
REVIEW
Vasiliki Manaki, Vangelis Bontinis, Alkis Bontinis, Argirios Giannopoulos, M D PhD Ioannis Kontes, Angeliki Chorti, Kiriakos Ktenidis
BACKGROUND: We conducted a systematic review to assess the safety and efficacy of Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy for the treatment of hemorrhoidal disease. METHODS: Our study was conducted in accordance with the PRISMA statement (Preferred Reporting Items for Systematic Reviews and Meta-analyses) 2020. Primary endpoints included overall recurrence and type of recurrence while secondary endpoints included postoperative complications, reintervention, presence of rectal ulcer, rectal stricture, defecation abnormalities and perianal abscess...
March 1, 2024: Acta Chirurgica Belgica
https://read.qxmd.com/read/38414123/transanal-opening-of-the-intersphincteric-space-tropis-a-novel-procedure-on-the-horizon-to-effectively-manage-high-complex-anal-fistulas
#9
JOURNAL ARTICLE
Pankaj Garg, Anvesha Mongia
Anal fistulas, especially complex and high fistulas, are difficult to manage. The transanal opening of the intersphincteric space (TROPIS) procedure was first described in 2017, and a high success rate of over 90% was reported in high complex fistulas. Since then, more studies and even a meta-analysis have corroborated the high efficacy of this procedure in high fistulas. Conventionally, the main focus was to close the internal (primary) opening for the fistula to heal. However, most complex fistulas have a component of the fistula tract in the intersphincteric plane...
February 2024: Annals of Coloproctology
https://read.qxmd.com/read/38399580/perirectal-abscess-with-anterior-extension-to-the-extraperitoneum-and-space-of-retzius-a-case-report
#10
Hsiang Teng, Po-Hsien Wu
Introduction -This report illuminates the distinctive features of a successfully managed Retzius space infection arising from a complex perirectal abscess. It adds novel insights to the scientific literature by addressing the rarity of such occurrences, highlighting the diagnostic complexities associated with extraperitoneal spread, and underscoring the crucial role of a nuanced understanding of anatomy in navigating clinical scenarios involving anorectal abscesses. Patient's Main Concerns and Important Clinical Findings -A 68-year-old male presented with dizziness and diffuse lower abdominal pain, accompanied by intermittent perianal pain for one month...
February 8, 2024: Medicina
https://read.qxmd.com/read/38357940/clinical-outcomes-before-and-after-prucalopride-treatment-an-observational-study-in-patients-with-chronic-idiopathic-constipation-in-the-usa
#11
JOURNAL ARTICLE
Anthony Lembo, Brooks D Cash, Mei Lu, Emi Terasawa, Brian Terreri, Shawn Du, Rajeev Ayyagari, Paul Feuerstadt, Baharak Moshiree, Ben Westermeyer, Selina Pi, Mena Boules
INTRODUCTION: This real-world US-based claims study compared constipation-related symptoms and complications 6 months before and after prucalopride initiation in adults with chronic idiopathic constipation (CIC). METHODS: This observational, retrospective cohort analysis used the IBM MarketScan® Commercial Claims and Encounters and the Medicare Supplemental databases (January 2015-June 2020). Prucalopride-treated patients (≥18 years old) who had ≥1 constipation-related International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) diagnosis code during the baseline or study period were included...
February 15, 2024: Clinical and Translational Gastroenterology
https://read.qxmd.com/read/38345513/lymphogranuloma-venereum-an-unusual-cause-of-rectal-stenosis
#12
JOURNAL ARTICLE
Alejandro Hueso Mor, Ana Soto Sánchez, María de Armas-Conde, Ricardo Hernández-Alonso, Eduardo Pérez Sánchez, Moisés Hernández Barroso, Julio César Jordán-Balanzá
Lymphogranuloma Venereum (LGV) is a notifiable disease linked to high-risk sexual practices such as cruising, chemsex, or orgies. The anorectal manifestation is associated with receptive anal sex and presents with characteristic symptoms such as proctitis, tenesmus, suppuration, and in advanced cases, anorectal fistulas or stenosis. The case of a 57-year-old man engaging in high-risk sexual practices is presented, showing symptoms such as discharge, fistulizations, rectal stenosis, and a weight loss of 15 kg...
February 12, 2024: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/38342913/case-report-atypical-presentation-of-mpox-with-massive-hematochezia-and-prolonged-viral-shedding-despite-tecovirimat-treatment
#13
JOURNAL ARTICLE
Sung Un Shin, Younggon Jung, Seong Eun Kim, Dong Min Kim
BACKGROUND: The outbreak of mpox that occurred between 2022 and 2023 is primarily being transmitted through sexual contact. As of now, there is no consensus on the recommended duration of isolation to prevent sexual transmission of the virus. Moreover, this particular mpox outbreak has presented with distinct complications in comparison to previous occurrences. In this report, we present a case involving severe rectal bleeding from an ulcer in a mpox patient with a history of engaging in receptive sexual contact...
February 12, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38303359/-a-case-of-radical-resection-after-neoadjuvant-chemotherapy-for-rectal-cancer-with-pelvic-abscess
#14
JOURNAL ARTICLE
Mao Osaki, Yusuke Takahashi, Shinji Tokuyama, Kenji Kawai, Yuki Matsui, Reishi Toshiyama, Masaaki Yamamoto, Kenji Sakai, Atsushi Takeno, Kunihito Gotoh, Michihiko Miyazaki, Koji Takami, Motohiro Hirao, Takeshi Kato
A 66-year-old man with a history of frequent diarrhea was diagnosed with rectal cancer with obstruction and a pelvic abscess. Following a transverse colostomy, he was referred to our hospital. The initial diagnosis was rectal cancer(cT4a N1bM0, cStage Ⅲb)and a pelvic abscess due to tumor perforation. To address this condition, we performed neoadjuvant chemotherapy using a combination of 5-fluorouracil, Leucovorin, oxaliplatin, and irinotecan(FOLFOXIRI). Following 6 courses of FOLFOXIRI, the abscess disappeared and no signs of tumor progression and distant metastases were detected...
December 2023: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38283447/horseshoe-abscess-as-a-rare-complication-after-transanal-hemorrhoid-dearterialization-with-mucopexy-a-case-report
#15
Yuki Nakao, Heather Reeves, David A Denning, James Martin
Transanal hemorrhoidal dearterialization (THD) is a minimally invasive procedure that has gained popularity as a treatment for symptomatic hemorrhoids. It involves ligating the arterial blood supply to the hemorrhoidal plexus. Compared to conventional ligation or resection, THD is associated with less postoperative bleeding and pain, allowing for same-day surgery discharge. Horseshoe abscess is a rare but known complication of anorectal surgery, characterized by an abscess that extends around the anal canal, often involving the ischiorectal fossa and adjacent structures...
December 2023: Curēus
https://read.qxmd.com/read/38280271/diagnosis-and-management-of-complications-following-pelvic-organ-prolapse-surgery-using-a-synthetic-mesh-french-national-guidelines-for-clinical-practice
#16
REVIEW
Xavier Deffieux, Marie-Aimée Perrouin-Verbe, Sandrine Campagne-Loiseau, Laurence Donon, Amélie Levesque, Jérome Rigaud, Nadja Stivalet, Aurélien Venara, Thibault Thubert, Adrien Vidart, Pierre-Olivier Bosset, Christine Revel-Delhom, Jean-Philippe Lucot, Jean François Hermieu
UNLABELLED: Complications associated with pelvic organ prolapse (POP) surgery using a synthetic non-absorbable mesh are uncommon (<5%) but may be severe and may hugely diminish the quality of life of some women. In drawing up these multidisciplinary clinical practice recommendations, the French National Authority for Health (Haute Autorité de santé, HAS) conducted an exhaustive review of the literature concerning the diagnosis, prevention, and management of complications associated with POP surgery using a synthetic mesh...
March 2024: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/38239011/the-harmful-effects-of-overlooking-acute-bacterial-prostatitis
#17
REVIEW
Youngmin Yang, Katsumi Shigemura, Koki Maeda, Michika Moriwaki, Kuan-Chou Chen, Yuzo Nakano, Masato Fujisawa
Prostatitis is a major urological disease affecting 25%-50% of men over their lifetime. However, prostatitis is often overlooked in nonurologic departments due to its sometimes indeterminate symptoms. In this review, we describe how to recognize and treat acute bacterial prostatitis, which manifests as a clinical problem in other departments as well as urology, to help prevent this disease from being overlooked. There are several possible negative effects of not recognizing acute bacterial prostatitis (ABP)...
January 18, 2024: International Journal of Urology: Official Journal of the Japanese Urological Association
https://read.qxmd.com/read/38174165/robotic-sigmoidectomy-with-natural-orifice-specimen-extraction-a-single-center-experience
#18
JOURNAL ARTICLE
Naved Salim, Camryn Daidone, Leslie Smith, Ahsan Raza
Background Natural orifice specimen extraction (NOSE) involves the removal of specimens through a naturally occurring orifice, such as the anus, rather than trans-abdominal extraction. NOSE procedures have been shown to significantly reduce postoperative complications and improve healing.  Objective The purpose of this case series is to report the outcomes of 27 patients undergoing sigmoidectomies through natural orifice specimen extraction. Materials and methods We carefully recorded demographic data on age and BMI, as well as operative data on surgical indication, and length of stay...
December 2023: Curēus
https://read.qxmd.com/read/38161867/rectum-perforation-secondary-to-ingested-chicken-bone-presenting-as-peri-anal-abscess-a-case-report
#19
Feras ALsannaa, Reem Bin Saleem, Jawaher ALowayyid
Rectal perforation secondary to an ingested foreign body is a rare occurrence that can be challenging to diagnose. It may initially present as a perianal abscess. Herein, we report a rare incident involving a patient who presented with a perianal abscess. The initial assessment and an abdominal CT scan revealed a large horseshoe perianal abscess with a small linear hyperdensity noted near the anal verge. The patient was taken to the operating room, where he was found to have perforated the rectum due to an ingested chicken bone...
November 2023: Curēus
https://read.qxmd.com/read/38159724/first-detection-in-spain-of-ndm-1-producing-pseudomonas-aeruginosa-in-two-patients-transferred-from-ukraine-to-a-university-hospital
#20
JOURNAL ARTICLE
Marta Hernández-García, Margarita Cabello, Manuel Ponce-Alonso, Pedro M Herrador-Gómez, Francesca Gioia, Javier Cobo, Rafael Cantón, Patricia Ruiz-Garbajosa
OBJECTIVES: Carbapenemase-mediated carbapenem resistance in Pseudomonas aeruginosa is a relevant health problem. We detected for the first time in Spain two clinical NDM-producing P. aeruginosa (NDM-Pa) isolates in two Ukrainian patients admitted to our hospital between April-August 2022. METHODS: Antimicrobial susceptibility was studied by microdilution and MIC gradient strips (EUCAST-2022 criteria). Carbapenemase genes were detected by the Xpert Carba-R and immunochromatography assays...
December 28, 2023: Journal of Global Antimicrobial Resistance
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