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CHADS2vasc score

Deepak Padmanabhan, Krishna Kancharla, Majd A El-Harasis, Ameesh Isath, Nayani Makkar, Peter A Noseworthy, Paul A Friedman, Yong-Mei Cha, Suraj Kapa
BACKGROUND: Implantable loop recorders (ILRs) are effective in achieving symptom-rhythm correlation, However, diagnostic yield in routine clinical practice is not as well established. METHODS: Patients undergoing ILR implantation between April 2010 and May 2015 were included. All devices were enrolled in remote monitoring with automatic arrhythmia detection and P sense algorithms switched 'ON'. Symptom-rhythm correlation was assessed and changes in management were recorded...
October 25, 2018: Pacing and Clinical Electrophysiology: PACE
Ömer Gedikli, Sanghamitra Mohanty, Chintan Trivedi, Carola Gianni, Qiong Chen, Domenico Giovanni Della Rocca, J David Burkhardt, Javier E Sanchez, Patrick Hranitzky, G Joseph Gallinghouse, Amin Al-Ahmad, Rodney Horton, Luigi Di Biase, Andrea Natale
BACKGROUND: Spontaneous echocardiographic contrast ("smoke") within the left atrial cavity on transesophageal echocardiography (TEE) suggests low blood flow velocities in the heart that may lead to thromboembolic (TE) events. OBJECTIVE: The purpose of this study was to evaluate the risk of TE events in the periprocedural period and at long-term follow-up in atrial fibrillation (AF) patients having dense smoke on preprocedural TEE. METHODS: A total of 2511 patients undergoing AF ablation were included in this analysis...
October 9, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Ayman Elbadawi, Islam Y Elgendy, Le Dung Ha, Basarat Baig, Marwan Saad, Hussain Adly, Gbolahan O Ogunbayo, Odunayo Olorunfemi, Matthew S Mckillop, Scott A Maffett
Limited data are available regarding the impact of cancer on cerebrovascular accidents in patients with atrial fibrillation (AF). We queried the Nationwide Inpatient Survey Database to identify patients who have diagnostic code for AF. We performed a 1:1 propensity matching based on the CHA2 DS2 VASc score and other risk factors between patients with AF who had lung, breast, colon, and esophageal cancer, and those who did not (control). The final cohort included a total of 31,604 patients. The primary outcome of in-hospital cerebrovascular accidents (CVA) was lower in the cancer group than in the control group (4% vs 7%, p < 0...
March 1, 2018: American Journal of Cardiology
Marco Roberto, Amir-Ali Fassa, Edoardo De Benedetti
Embolic stroke is the most dangerous complication of atrial fibrillation (AF). Oral anticoagulation represents the treatment of choice for thromboembolic (TE) prophylaxis in patients with a CHADS2VASc score ≥ 1 but is associated with a significant increase in haemorrhagic events. Almost 90 % of thrombi originate in the left atrial appendage. Registries have shown that percutaneous occlusion of this appendage reduces embolic risk and may be considered for TE prophylaxis in patients with a high TE (CHADS2VASc score ≥ 2) and haemorrhagic (HAS-BLED score ≥ 3) risk...
March 1, 2017: Revue Médicale Suisse
Cátia Costa, Teresa González-Alujas, Filipa Valente, Carlos Aranda, José Rodríguez-Palomares, Laura Gutierrez, Giuliana Maldonado, Laura Galian, Gisela Teixidó, Artur Evangelista
BACKGROUND: Left atrial deformation (LAD) parameters are new markers of atrial structural remodelling that seem to be affected in atrial fibrillation (AF) and atrial flutter (AFL). This study aimed to determine whether LAD can identify patients with a higher risk of thrombosis and unsuccessful electrical cardioversion (ECV). METHODS: Retrospective study including 56 patients with AF or AFL undergoing ECV, with previous transthoracic (TTE) and transoesophageal echocardiography (TEE) studies...
June 2016: Echo Research and Practice
Haiyan Xu, Christian T Ruff, Robert P Giugliano, Sabina A Murphy, Francesco Nordio, Indravadan Patel, Minggao Shi, Michele Mercuri, Elliott M Antman, Eugene Braunwald
BACKGROUND: We studied the concomitant use of single antiplatelet therapy (SAPT) on the efficacy and safety of the anti-Xa agent edoxaban in patients with atrial fibrillation (AF). METHODS AND RESULTS: ENGAGE AF-TIMI 48 was a randomized trial that compared 2 dose regimens of edoxaban with warfarin. We studied both the approved high-dose edoxaban regimen (HDER; 60 mg daily reduced by one half in patients with anticipated increased drug exposure), as well as a lower-dose edoxaban regimen (LDER; 30 mg daily, also reduced by one half in patients with anticipated increased drug regimen)...
February 23, 2016: Journal of the American Heart Association
Sampath Gunda, Madhu Reddy, Jayant Nath, Hosakote Nagaraj, Moustapha Atoui, Abdi Rasekh, Christopher R Ellis, Nitish Badhwar, Randall J Lee, Luigi DI Biase, Moussa Mansour, Jeremy N Ruskin, Andrea Natale, Matthew Earnest, Dhanunjaya R Lakkireddy
INTRODUCTION: Left atrial appendage (LAA) can be effectively and safely excluded using a novel percutaneous LARIAT ligation system. However, due to pericardial catheter manipulation and LAA ligation and subsequent necrosis, postprocedural course is complicated by pericarditis. We intended to evaluate the preprocedural use of colchicine on the incidence of postprocedural pericardial complications. METHODS AND RESULTS: In this multicenter observational study, we included all consecutive patients who underwent LARIAT procedure at the participating centers...
January 2016: Journal of Cardiovascular Electrophysiology
Bahij Kreidieh, Francia Rojas, Paul Schurmann, Amish S Dave, Amir Kashani, Moisés Rodríguez-Mañero, Miguel Valderrábano
BACKGROUND: Left atrial appendage (LAA) ligation with the Lariat device is being used for stroke prevention in atrial fibrillation. Residual leaks into the LAA are commonly reported after the procedure. Little is known about the anatomic LAA remodeling after Lariat ligation. METHODS AND RESULTS: In an exploratory study, we evaluated LAA 3-dimensional geometry via computed tomographic scan in 31 consecutive patients before Lariat closure and after a minimum of 30 days post procedure...
December 2015: Circulation. Arrhythmia and Electrophysiology
Hui-Chin Lai, Wu-Chien Chien, Chi-Hsiang Chung, Wen-Lieng Lee, Kuo-Yang Wang, Tsu-Juey Wu, Chia-Ning Liu, Tsun-Jui Liu
BACKGROUND: Traffic accidents account for a substantial proportion of premature disabilities and deaths. Whether atrial fibrillation (AF) provokes while antithrombotics prevent from such events remains un-investigated. METHODS: All patients ≥40years with newly diagnosed AF in 2005 were scrutinized from the "Longitudinal Health Insurance Database 2005" (1 million beneficiaries) of Taiwan's National Health Insurance Institute as the AF group. Four-fold number of age-, gender-, and comorbidity-matched patients but without AF served as the Non-AF controls...
October 15, 2015: International Journal of Cardiology
Kyung Hwan Kim, Wan Kim, Sun Ho Hwang, Won Yu Kang, Sang Cheol Cho, Weon Kim, Myung Ho Jeong
BACKGROUND: The CHA2DS2VASc score has been used to evaluate the risk of thromboembolic events in atrial fibrillation. However, because all the components of CHA2DS2VASc are important cardiovascular risk factors, we decided to evaluate the effectiveness of CHA2DS2VASc score as a long-term predictor for prognosis in acute myocardial infarction (AMI) patients. METHODS: We enrolled 15,681 AMI patients for the Korean Working Group in Acute Myocardial Infarction (KORMI) consecutively and analyzed retrospectively...
February 2015: Journal of Cardiology
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