Mariann Koel, Kaarel Krjutškov, Merli Saare, Külli Samuel, Dmitri Lubenets, Shintaro Katayama, Elisabet Einarsdottir, Eva Vargas, Alberto Sola-Leyva, Parameswaran Grace Lalitkumar, Kristina Gemzell-Danielsson, David Blesa, Carlos Simon, Fredrik Lanner, Juha Kere, Andres Salumets, Signe Altmäe
STUDY QUESTION: Which genes regulate receptivity in the epithelial and stromal cellular compartments of the human endometrium, and which molecules are interacting in the implantation process between the blastocyst and the endometrial cells? SUMMARY ANSWER: A set of receptivity-specific genes in the endometrial epithelial and stromal cells was identified, and the role of galectins (LGALS1 and LGALS3), integrin β1 (ITGB1), basigin (BSG) and osteopontin (SPP1) in embryo-endometrium dialogue among many other protein-protein interactions were highlighted...
2022: Human Reproduction Open