Chuan-Xiang Li, Liu Zhang, Ya-Ru Yan, Yong-Jie Ding, Ying-Ni Lin, Jian-Ping Zhou, Ning Li, Hong-Peng Li, Shi-Qi Li, Xian-Wen Sun, Qing-Yun Li
Saliva is abundant with proteins, metabolites, DNA, and a diverse range of bacterial species. During the past two decades, saliva has emerged as a novel diagnostic and evaluation medium for several diseases. Collection of saliva samples is simple, minimally invasive, and convenient even in infants, children, and patients with anxious. Furthermore, with the development of hypersensitive techniques [e.g., microsensor arrays, enzyme-labeled immunosensors, nanoparticle-labeled immunosensors, capacitive or impedimetric immunosensors, magneto immunosensors, field effect transistor immunosensors, and surface enhanced Raman spectroscopy (SERS)], the sensitivity and accuracy of saliva diagnostic procedures have been improved...
July 2021: Journal of Thoracic Disease