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Schagen van leeuwen

M K Van de Waarsenburg, M I J Withagen, F van den Noort, J H Schagen van Leeuwen, C H van der Vaart
OBJECTIVES: The primary objective of this study was to confirm our previous observation that hiatal dimensions and mean echogenicity of the puborectalis muscle (MEP) were statistically significant different at 12 weeks gestation in women who delivered by a caesarean section (CS) due to failure to progress (FTP), compared to women who delivered vaginally. The secondary objective was to assess the association between the echogenicity of the cervix and the vastus lateralis muscle and mode of delivery...
November 21, 2018: Ultrasound in Obstetrics & Gynecology
Femke E M Mulder, Sytske van der Velde, Fraukje Pol, Marjolein Bos, Jules Schagen van Leeuwen, Viviane Dietz, Robert A Hakvoort, Jan-Paul W R Roovers
INTRODUCTION AND HYPOTHESIS: Abnormal postvoid residual volumes (PVRV) after delivery are common in daily clinical practice. By using an automatic scanning device, unnecessary catheterizations can be prevented. The aim of this study was to determine the accuracy of PVRV after vaginal delivery measured by an automatic scanning device through a comparison with transurethral catheterization. MATERIALS AND METHODS: This prospective observational equivalence study was performed in patients who delivered vaginally between June 2012 and May 2017 in three teaching hospitals in The Netherlands...
June 27, 2018: International Urogynecology Journal
Willemien J van Driel, Simone N Koole, Karolina Sikorska, Jules H Schagen van Leeuwen, Henk W R Schreuder, Ralph H M Hermans, Ignace H J T de Hingh, Jacobus van der Velden, Henriëtte J Arts, Leon F A G Massuger, Arend G J Aalbers, Victor J Verwaal, Jacobien M Kieffer, Koen K Van de Vijver, Harm van Tinteren, Neil K Aaronson, Gabe S Sonke
BACKGROUND: Treatment of newly diagnosed advanced-stage ovarian cancer typically involves cytoreductive surgery and systemic chemotherapy. We conducted a trial to investigate whether the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery would improve outcomes among patients who were receiving neoadjuvant chemotherapy for stage III epithelial ovarian cancer. METHODS: In a multicenter, open-label, phase 3 trial, we randomly assigned 245 patients who had at least stable disease after three cycles of carboplatin (area under the curve of 5 to 6 mg per milliliter per minute) and paclitaxel (175 mg per square meter of body-surface area) to undergo interval cytoreductive surgery either with or without administration of HIPEC with cisplatin (100 mg per square meter)...
January 18, 2018: New England Journal of Medicine
Blanka Vasak, Elisabeth M Graatsma, Elske Hekman-Drost, Marinus J Eijkemans, Jules H Schagen van Leeuwen, Gerard H A Visser, Benoit C Jacod
INTRODUCTION: Worldwide induction and cesarean delivery rates have increased rapidly, with consequences for subsequent pregnancies. The majority of intrapartum cesarean deliveries are performed for failure to progress, typically in nulliparous women at term. Current uterine registration techniques fail to identify inefficient contractions leading to first-stage labor arrest. An alternative technique, uterine electromyography has been shown to identify inefficient contractions leading to first-stage arrest of labor in nulliparous women with spontaneous onset of labor at term...
July 2017: Acta Obstetricia et Gynecologica Scandinavica
S Rebers, E Vermeulen, A P Brandenburg, T J Stoof, B Zupan-Kajcovski, W J W Bos, M J Jonker, C J Bax, W J van Driel, V J Verwaal, M W van den Brekel, J C Grutters, R A Tupker, L Plusjé, R de Bree, J H Schagen van Leeuwen, E G J Vermeulen, R A de Leeuw, R M Brohet, N K Aaronson, F E Van Leeuwen, M K Schmidt
BACKGROUND: Despite much debate, there is little evidence on consequences of consent procedures for residual tissue use. Here, we investigated these consequences for the availability of residual tissue for medical research, clinical practice, and patient informedness. METHODS: We conducted a randomised clinical trial with three arms in six hospitals. Participants, patients from whom tissue had been removed for diagnosis or treatment, were randomised to one of three arms: informed consent, an opt-out procedure with active information provision (opt-out plus), and an opt-out procedure without active information provision...
2016: PloS One
J Marinus van der Ploeg, Katrien Oude Rengerink, Annemarie van der Steen, Jules H Schagen van Leeuwen, C Huub van der Vaart, Jan-Paul W R Roovers
INTRODUCTION AND HYPOTHESIS: We compared pelvic organ prolapse (POP) repair with and without midurethral sling (MUS) in women with occult stress urinary incontinence (SUI). METHODS: This was a randomized trial conducted by a consortium of 13 teaching hospitals assessing a parallel cohort of continent women with symptomatic stage II or greater POP. Women with occult SUI were randomly assigned to vaginal prolapse repair with or without MUS. Women without occult SUI received POP surgery...
July 2016: International Urogynecology Journal
Blanka Vasak, Elisabeth M Graatsma, Elske Hekman-Drost, Marinus J Eijkemans, Jules H Schagen van Leeuwen, Gerard H Visser, Benoit C Jacod
OBJECTIVE: We sought to study whether uterine electromyography (EMG) can identify inefficient contractions leading to first-stage labor arrest followed by cesarean delivery in term nulliparous women with spontaneous onset of labor. STUDY DESIGN: EMG was recorded during spontaneous labor in 119 nulliparous women with singleton term pregnancies in cephalic position. Electrical activity of the myometrium during contractions was characterized by its power density spectrum (PDS)...
September 2013: American Journal of Obstetrics and Gynecology
T N Schuurman, A Stiekema, J H Schagen van Leeuwen, R H M Verheijen
OBJECTIVE: The aim of this case report and review of the literature was to evaluate the effect of adding pelvic and/or para-aortic lymphadenectomy to hysterectomy and bilateral salpingo-oophorectomy (BSO) on the five year recurrence-free survival in patients with clinical Stage II endometrial carcinoma. MATERIALS AND METHODS: A Pubmed, Embase, and Cochrane library search was performed to identify relevant articles. After screening, using predetermined exclusion and inclusion criteria, and critical appraisal, a final of four articles remained...
2012: European Journal of Gynaecological Oncology
Femke van der Leij, Willibrord C M Weijmar Schultz, Harry van de Wiel, Jules H Schagen van Leeuwen
Premenstrual syndrome (PMS) is characterised by the occurrence of physical and psychological symptoms during the luteal phase of almost every menstrual cycle. These symptoms disappear at the beginning of menstruation, and a symptom-free period of at least a week ensues. Premenstrual dysphoric disorder (PMDD) is a variation of PMS, with predominantly psychological symptoms. The aetiology of PMD and PMDD is not known. A possible explanation however is an abnormal, stronger reaction to physiologically normal hormonal fluctuations...
2010: Nederlands Tijdschrift Voor Geneeskunde
Tessa Cox, Jan-Willem van der Steeg, Pieternel Steures, Peter G A Hompes, Fulco van der Veen, Marinus J C Eijkemans, Jules H Schagen van Leeuwen, Cees Renckens, Patrick M M Bossuyt, Ben W J Mol
OBJECTIVE: To assess the time to spontaneous ongoing pregnancy after a previous miscarriage in subfertile couples. DESIGN: A prospective cohort study. SETTING: The study was conducted in 38 fertility centers in the Netherlands. PATIENT(S): Subfertile couples who miscarried after completing their basic fertility work-up. INTERVENTION(S): Expectant management after a miscarriage. MAIN OUTCOME MEASURE(S): Spontaneous ongoing pregnancy...
July 2010: Fertility and Sterility
Jules H Schagen van Leeuwen, Rainer R Lange, Aino Fianu Jonasson, Wei J Chen, Lars Viktrup
OBJECTIVES: To evaluate the efficacy and safety of duloxetine in community-dwelling women > or =65 years with stress urinary incontinence (SUI) or stress-predominant mixed urinary incontinence (S-MUI) versus placebo. METHODS: Patients were randomly assigned for 12 weeks to placebo (N=134) or duloxetine (N=131) (20mg twice daily [BID] for 2 weeks and 40 mg BID for an additional 10 weeks), followed by a double-blind 4-week dose de-escalation/discontinuation phase...
June 20, 2008: Maturitas
L E Visser, S Kyei-Faried, D W Belcher, D W Geelhoed, J Schagen van Leeuwen, J van Roosmalen
This study compares two antivenoms used to treat Echis ocellatus snake bite patients at Mathias Hospital, Yeji, central Ghana. FAV-Afrique antivenom (Aventis Pasteur) was given to 278 patients during 2001--2003, whilst Asna Antivenom C (Bharat Serum and Vaccines Ltd) was used in 2004 to treat 66 patients. The two groups had comparable patient attributes, time from snake bite to treatment and staff adherence to the tested treatment protocol. The antivenom C group required more repeat doses and twice the amount of antivenom to treat coagulopathy...
May 2008: Transactions of the Royal Society of Tropical Medicine and Hygiene
P H T J Slee, R I F van der Waal, J H Schagen van Leeuwen, R A Tupker, R Timmer, C A Seldenrijk, M A M van Steensel
Acquired hypertrichosis lanugo-type or hypertrichosis lanuginosa acquisita (HLA) is often associated with metabolic and endocrine disorders and use of certain drugs. The occurrence of HLA with malignancy was first noted in 1865, and it has since been described in 56 patients as a paraneoplastic syndrome both in women and in men. Sometimes HLA occurs concurrent with acanthosis nigricans, papillary hypertrophy of the tongue, and glossitis. The predominance of female cases is striking. Malignancy-associated HLA seems to occur especially in the age group 40-70 years...
December 2007: British Journal of Dermatology
Diederike Geelhoed, Florence Agadzi, Lucia Visser, Emelia Ablordeppey, Kofi Asare, Peter O'Rourke, Jules Schagen van Leeuwen, Jos van Roosmalen
BACKGROUND: Various factors contribute to severe anemia in pregnancy in low-income countries. This study assesses which of these are of importance in rural Ghana, and evaluates management. METHODS: Prospective case-control study in two (sub)district hospitals in rural Ghana among 175 severely anemic pregnant women (Hb < 8.0 g/dl), receiving a comprehensive treatment package; and 152 non-anemic pregnant women (Hb > or = 10.9 g/dl), giving birth at the study hospitals, matched for age and parity...
2006: Acta Obstetricia et Gynecologica Scandinavica
Jules H Schagen van Leeuwen, Ramiro Castro, Michael Busse, Bart L H Bemelmans
OBJECTIVES: We reviewed placebo responses in randomised controlled trials (RCTs) for pharmacologic treatment of lower urinary tract symptoms (LUTS), including urinary incontinence (UI), overactive bladder, and benign prostatic hyperplasia. Review papers on placebo effects in non-urologic disorders were assessed to compare the magnitude of placebo responses in drugs for LUTS with those reported for other diseases. METHODS: Data were retrieved from registration trials for LUTS drugs on the Web sites of the Food and Drugs Administration and the European Medicines Agency...
September 2006: European Urology
Jan-Paul Roovers, Anske van der Bom, Jules Schagen van Leeuwen, Piet Scholten, Peter Heintz, Huub van der Vaart
OBJECTIVE: A prospective study was performed to evaluate the effects of genital prolapse surgery on sexuality. Additionally we investigated which variables are risk factors for persistence or development of sexual problems after surgery. METHODS: All 82 patients participating in a randomized trial comparing vaginal and abdominal surgical correction of descensus uteri, were asked to complete the Questionnaire for screening Sexual Dysfunctions (QSD) before and at six months and one year after surgery...
March 2006: Journal of Psychosomatic Obstetrics and Gynaecology
Edith A Sijmons, Marieke A L van Lankveld, Petronella O Witteveen, Petra H M Peeters, Veronica C M Koot, Jules Schagen van Leeuwen
OBJECTIVES: To assess compliance to current surgical staging and adjuvant treatment guidelines for patients with early-stage epithelial ovarian carcinoma and its impact on overall survival. METHODS: Patients diagnosed between 1991 and 1997 with early-stage ovarian cancer were recruited from the Regional Cancer Registry of the central region in the Netherlands. Demographic data, tumour characteristics, surgical findings and therapeutic data were abstracted from medical records...
April 2007: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Marieke A L van Lankveld, Nicole C M Koot, Petra H M Peeters, Jules Schagen van Leeuwen, Ina M Jürgenliemk-Schulz, Marion A van Eijkeren
RATIONALE, AIMS AND OBJECTIVES: We evaluated the adherence to treatment guidelines in early stage endometrial cancer and the influence of adherence to guidelines on overall survival. METHOD: Patients were identified in the central region in the Netherlands from 1990 till 1995. Patient and tumour characteristics, surgical findings, radiation and follow-up data were abstracted from medical records. Endpoint was overall survival. Kaplan-Meier method was used to perform time-to-event analysis...
April 2006: Journal of Evaluation in Clinical Practice
Diederike Geelhoed, Florence Agadzi, Lucia Visser, Emelia Ablordeppey, Kofi Asare, Peter O'Rourke, Jules Schagen Van Leeuwen, Jos Van Roosmalen
BACKGROUND: Anemia in pregnancy contributes to poor outcome for mother and child in low-income countries. This study analyzes adverse maternal and fetal outcome after severe anemia in pregnancy in rural Ghana. METHODS: A cohort study in two (sub)district hospitals, including 157 pregnant women exposed to severe anemia (Hb < 8.0 g/dl) and 152 nonexposed pregnant women (Hb > or = 10.9 g/dl), matched for age and parity strata. Adverse outcomes analyzed were postpartum hemorrhage, need for blood transfusion, maternal mortality, low birth-weight, and perinatal mortality...
2006: Acta Obstetricia et Gynecologica Scandinavica
Peter H Th J Slee, Fred J Verzijlbergen, Jules H Schagen van Leeuwen, Rutger I F van der Waal
No abstract text is available yet for this article.
January 20, 2006: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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