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GCF cortisol

Omer Cakmak, Banu Arzu Alkan, Ebru Saatci, Zekeriya Tasdemir
OBJECTIVES: The purpose of this prospective study was to investigate the effect of nonsurgical periodontal treatment (PT) on anxiety/depression scale scores and on gingival crevicular fluid (GCF) cortisol (COR) and dehydroepiandrosterone (DHEA) levels. METHODS: 55 participants with generalized chronic periodontitis (GCP group, n:21), localized chronic periodontitis (LCP group, n:19) and gingivitis/healthy(control group, n : 15) patients were treated and followed up for 6 months...
September 6, 2018: Oral Diseases
Fatma Ucan Yarkac, Ozge Gokturk, Osman Demir
OBJECTIVES: The aim of this study was to compare the effects of periodontal treatment on the inflammatory markers in gingival crevicular fluid and the concentration of salivary cortisol between non-pregnant and pregnant women with gingivitis. MATERIALS AND METHODS: This study included 30 non-pregnant women (mean age 27.93 ± 6.61 years) and 30 pregnant women (mean age 28.93 ± 4.04 years). Each participant presented with the clinical symptoms of generalized, moderate-to-severe gingivitis...
July 31, 2018: Clinical Oral Investigations
Omer Cakmak, Zekeriya Tasdemir, Cuneyt Asim Aral, Serkan Dundar, Halit Bugra Koca
AIM: This cross-sectional study aims to analyse cortisol and dehydroepiandrosterone (DHEA) levels in gingival crevicular fluid (GCF) and saliva in generalized aggressive periodontitis (GAP) and generalized chronic periodontitis (GCP) patients, as well as in periodontally healthy individuals (C). MATERIAL AND METHODS: A total of 92 patients (31 C, 34 GCP and 27 GAP) were included in the study. Clinical parameters including plaque index, gingival index, bleeding on probing, probing depth and clinical attachment level; psychosocial measurements including Beck depression inventory and state-trait anxiety inventory; and hormone levels in GCF and saliva including cortisol and DHEA were evaluated...
December 2016: Journal of Clinical Periodontology
Omer Cakmak, B Arzu Alkan, Saliha Ozsoy, Ahmet Sen, Ummuhan Abdulrezzak
BACKGROUND: The aim of the present study is to examine whether anxiety and depression scale scores change with regard to clinical periodontal status and to investigate the association between the levels of stress-related hormones in gingival crevicular fluid (GCF) and extent/severity of periodontal disease. METHODS: One hundred twenty participants who fulfilled the study inclusion criteria were chosen. Patients with chronic periodontitis (CP) and those with healthy periodontal tissues/mild gingivitis were included...
August 2014: Journal of Periodontology
Sangeeta Umesh Nayak, Dilip G Nayak, Ashita S Uppoor, K Keshava Pai
BACKGROUND: To evaluate gingival crevicular fluid (GCF) and salivary cortisol levels in anxious and non-anxious patients with chronic periodontitis. MATERIALS AND METHODS: A total of 45 patients with a mean age 43.4 ± 6.12 years were assigned to three groups: Healthy control group (Group 1), group with chronic periodontitis but no anxiety (Group 2) and group with chronic periodontitis and with anxiety (Group 3). State - Trait anxiety inventory and Hamilton Anxiety rating scale were used to assess the anxiety levels of all the subjects...
July 2013: Dental Research Journal
Özgün Özçaka, Nurcan Buduneli, Banu Ozturk Ceyhan, Aliye Akcali, Victoria Hannah, Christopher Nile, David F Lappin
BACKGROUND: Polycystic ovarian syndrome (PCOS) is a hormonal disorder of females of reproductive age that impacts their oral and systemic health. The aim of this study is to evaluate interleukin-17A (IL-17A), IL-17F, IL-17A/F, and IL-17E (IL-25) levels in gingival crevicular fluid (GCF), saliva, and serum of non-obese females with PCOS and with either a clinically healthy periodontium or gingivitis. METHODS: Thirty-one females with PCOS, 30 females with PCOS and gingivitis, and 12 systemically and periodontally healthy females participated in the study...
December 2013: Journal of Periodontology
Özgün Özçaka, Banu Öztürk Ceyhan, Aliye Akcali, Nurgün Biçakci, David F Lappin, Nurcan Buduneli
BACKGROUND: The aim of this study is to evaluate the gingival crevicular fluid (GCF), saliva, and serum concentrations of tumor necrosis factor-α (TNF-α), TNF-α receptor-1 (TNF-αR1), TNF-αR2, and interleukin-6 (IL-6) in non-obese females with polycystic ovary syndrome (PCOS) and either clinically healthy periodontium or gingivitis. METHODS: Thirty-one females with PCOS and healthy periodontium, 30 females with PCOS and gingivitis, and 12 systemically and periodontally healthy females were included in the study...
December 2012: Journal of Periodontology
A Johannsen, N Bjurshammar, A Gustafsson
OBJECTIVE: The aim of the present study was to investigate the effects of academic stress on periodontal health, in relation to inflammatory markers in gingival crevicular fluid (GCF) and cortisol in saliva. MATERIALS AND METHODS: The study included 20 healthy dental hygienists (females: mean age 29.3 +/- 8.5 SD) and was conducted during a major exam period and 4 weeks later after the exams. A clinical examination was performed and GCF was collected from four sites in each subject on these two occasions...
February 2010: International Journal of Dental Hygiene
Annsofi Johannsen, Gunnar Rylander, Birgitta Söder, Marie Asberg
BACKGROUND: The aim of the present study was to investigate the importance of stress for the development of periodontitis by comparing oral health status, proinflammatory markers, and cortisol in gingival crevicular fluid (GCF) and saliva in patients with stress-related mental depression and controls. METHODS: The participants consisted of 43 women with stress-related depression and exhaustion (Diagnostic and Statistical Manual of Mental Disorders, 4th edition [DSM-IV], with a mean age of 42...
August 2006: Journal of Periodontology
Renate Deinzer, Nicole Granrath, Holger Stuhl, Lars Twork, Helga Idel, Bernd Waschul, Armin Herforth
The combined effects of stress and antigen on interleukin-1beta (Il-1beta) have rarely been studied locally at the site of microbial challenges in vivo, so far. We here propose a model for the analysis of such effects in humans and examine its utility for acute stress trials. Twelve students (6 male, 6 female) refrained from oral hygiene in two antagonistic quadrants for 28 days to allow for increasing bacterial stimulation of the respective gingival sites due to accumulation of microbial plaque. Good oral hygiene was maintained in the remaining quadrants...
September 2004: Brain, Behavior, and Immunity
B Axtelius, S Edwardsson, E Theodorsson, G Svensäter, R Attström
Cortisol is one of the primary mediators of the stress response, in the main having immunosuppressive effects. An important component of the host response in periodontal inflammation is gingival crevicular fluid (GCF), with constituents mainly derived from serum. Cortisol, like many other steroids, is present in saliva but its occurrence in GCF does not seem to be documented. Unstimulated whole saliva was collected and GCF was sampled on filter disks. The samples were analysed by a modified RIA method for serum in such a way that small volumes and low concentrations could be measured...
November 1998: Journal of Clinical Periodontology
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