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Yongping Kou, Chaonan Li, Jiabao Li, Bo Tu, Yansu Wang, Xiangzhen Li
Denitrification is an important process that influences nitrogen (N) loss and the production of greenhouse gas in grassland soils. However, the relative contributions of abiotic and biotic factors to soil denitrification potential at the regional and sub-regional scales in grassland ecosystems remain elusive. In this study, soil samples were collected from 21 sites at three steppes of China, including the Inner Mongolia Plateau (IMP), the Xinjiang Autonomous Region (XAR) and the Tibetan Plateau (TP) grasslands...
March 8, 2019: Science of the Total Environment
Xiaobo Wang, Ya Hou, Qiuyue Li, Xuanhao Li, Wenxiang Wang, Xiaopeng Ai, Tingting Kuang, Xiaorui Chen, Yi Zhang, Jing Zhang, Yao Hu, Xianli Meng
ETHNOPHARMACOLOGICAL RELEVANCE: Rhodiola crenulata, a traditional Tibetan medicine, has shown promise in the treatment of hypobaric hypoxia (HH)-induced brain injury. However, the underlying mechanisms remain unclear. This study investigated the protective effects of R. crenulata aqueous extract (RCAE) on HH-induced brain injury in rats. MATERIALS AND METHODS: An animal model of high-altitude hypoxic brain injury was established in SD rats using an animal decompression chamber for 24 h...
March 13, 2019: Journal of Ethnopharmacology
Feng Song, Mingkun Xie, Bowen Xie, Shuangshuang Wang, Miao Liao, Haibo Luo
Y-Chromosomal short tandem repeat polymorphisms (Y-STRs) are widely applied in human forensic cases and population genetic studies. There is a lack of information about the Sichuan Tibetan population in the Y-STR Haplotype Reference Database (YHRD, , release 59). In this study, 502 unrelated male individuals residing in the Sichuan Province were recruited and genotyped at 29 Y-STR loci. A total of 479 haplotypes were observed, 460 (96.03%) of which were unique. The haplotype diversity (HD) and discrimination capacity (DC) for the Sichuan Tibetan population were 0...
March 14, 2019: International Journal of Legal Medicine
Xiaoxia Wu, Liu Liu, Jianke Li, Fumin Chi
Ovalbumin peptides are food protein-derived fragments comprised of amino acid residues. The bioactive properties of the peptides are determined by the inherent amino acid composition and sequence of the peptide. The objective of this study was to evaluate the proteomics characteristics in Tibetan chicken egg ovalbumin peptides, compared to ordinary eggs, using isobaric tags for the relative and absolute quantification labelling technique (iTRAQ). The results showed that 165 proteins were identified and 56 proteins were significantly changed including 34 significantly upregulated and 22 significantly downregulated proteins...
March 12, 2019: International Journal of Biological Macromolecules
Wei Wang, Wen Xu, Zhang Wen, Dandan Wang, Sen Wang, Zhiwei Zhang, Yuanhong Zhao, Xuejun Liu
Atmospheric reactive nitrogen (N) deposition has been proven to be an important nutrient input from external environments to forest ecosystems. However, the magnitude of atmospheric N deposition in the Tibetan region of China is not well known. In this study, multi-year (between 2005 and 2016) measurements of dry and wet N deposition were carried out in Nyingchi (NC) city, southeastern Tibet. Bulk deposition was collected by the rain gauge method; dry deposition was calculated by the inferential method, namely, multiplying ambient N concentrations by dry deposition velocity (Vd ) of the N species...
March 15, 2019: Scientific Reports
Congyi Zheng, Zuo Chen, Linfeng Zhang, Xin Wang, Ying Dong, Jiali Wang, Lan Shao, Ye Tian, Zengwu Wang
Background Data regarding the metabolic risk factors clustering on the risk of left ventricular diastolic dysfunction ( LVDD ) are lacking among people living at high altitude and under hypoxic conditions. In this study, we explored the association between metabolic risk factor clustering and LVDD among the Tibetan population of China. Methods and Results We conducted a cross-sectional survey in a representative sample of 1963 Tibetans in 2014 to 2016. Grading LVDD was based on recommendations for the evaluation of LV diastolic function by echocardiography (2009)...
March 19, 2019: Journal of the American Heart Association
Bo Zhang, Dongmei Ban, Xiao Gou, Yawen Zhang, Lin Yang, Yangzom Chamba, Hao Zhang
Background: Tibetan pigs, which inhabit the Tibetan Plateau, exhibit distinct phenotypic and physiological characteristics from those of lowland pigs and have adapted well to the extreme conditions at high altitude. However, the genetic and epigenetic mechanisms of hypoxic adaptation in animals remain unclear. Methods: Whole-genome DNA methylation data were generated for heart tissues of Tibetan pigs grown in the highland (TH, n  = 4) and lowland (TL, n  = 4), as well as Yorkshire pigs grown in the highland (YH, n  = 4) and lowland (YL, n  = 4), using methylated DNA immunoprecipitation sequencing...
2019: Journal of Animal Science and Biotechnology
Shan-Shan Zhou, Zhen Xing, Hui Liu, Xian-Ge Hu, Qiong Gao, Jie Xu, Si-Qian Jiao, Kai-Hua Jia, Yu Qing Jin, Wei Zhao, Ilga Porth, Yousry A El-Kassaby, Jian-Feng Mao
BACKGROUND: Cupressus gigantea, a rare and endangered tree species with remarkable medicinal value, is endemic to the Tibetan Plateau. Yet, little is known about the underlying genetics of the unique ecological adaptability of this extremely long-lived conifer with a large genome size. Here, we present its first de novo and multi-tissue transcriptome in-depth characterization. RESULTS: We performed Illumina paired-end sequencing and RNA libraries assembly derived from terminal buds, male and female strobili, biennial leaves, and cambium tissues taken from adult C...
March 13, 2019: BMC Genomics
Junhua Hu, Yan Huang, Jianping Jiang, Antoine Guisan
Mountains, representing storehouses of biodiversity, endemism, and threatened species, are biodiversity hotspots of great conservation importance. However, increasing evidence indicates that mountain species throughout the world are responding to climate change, past or contemporary, by shifting their geographic distributions and patterns of genetic diversity, potentially affecting their adaptive capacity and increasing risk of extinction. Using the iconic high-elevation frog Nanorana parkeri as indicator, we showed how spatial analyses of climatic stability combined with genetic data allow unravelling amphibian responses to past and future climate changes on 'the roof of the world'-the Qinghai-Tibetan Plateau...
March 12, 2019: Journal of Animal Ecology
Xiaoxia Wang, Jing Yang, Shan Lu, Xin-He Lai, Dong Jin, Ji Pu, Lina Niu, Wentao Zhu, Junrong Liang, Ying Huang, Bin Wang, Xiaomin Wu, Hao Liang, Jianguo Xu
Two rod-shaped, slightly halophilic and extremely halotolerant bacterial strains (X-1125T and X-1174), which were Gram-stain-positive, facultatively anaerobic and motile with peritrichous flagella, were isolated from the faeces of Tibetan antelopes. Their optimal temperature, NaCl concentration and pH for growth were 28 °C, 3 % (w/v) NaCl and pH 7.5, respectively. Based on the results of 16S rRNA gene sequences, and phylogenetic and phylogenomic analyses, their nearest phylogenetic neighbours were Paraliobacillussediminis KCTC 33762T (98...
March 12, 2019: International Journal of Systematic and Evolutionary Microbiology
Xiao Cai, Huixia Cai, Qing Gan, Wenxu Chang, Fang Yuan, Wei Luo, Jie Sun, Jing An
Cystic echinococcosis (CE) is a common, chronic, and endemic zoonotic disease usually localized in a single organ; multivisceral cases are rare, especially outside the liver or lung. Here, we describe an unusual case of a 43-year-old Tibetan man with echinococcosis of the infratemporal fossa, heart, liver, pancreas, abdomen, and pelvic cavity. He only presented with diminished vision of the left eye, especially when chewing. Computed tomography and magnetic resonance imaging revealed multivisceral CE. The patient underwent surgery for the excision of a cyst in the infratemporal fossa, as well as chemotherapy, and the diagnosis was confirmed by histopathological examination...
March 11, 2019: American Journal of Tropical Medicine and Hygiene
Yangong Du, Kai Shu, Xiaowei Guo, Zhu Pengjin
Grasslands are suffering from long-term overgrazing because of the population inflation. Furthermore, nitrous oxide (N2 O) is a major greenhouse gas that also depletes stratospheric ozone. However, the emission rate of grassland N2 O and underlying mechanisms remained unclear under different grazing intensities. We conducted a field manipulation under four grazing intensities to compare its N2 O fluxes and main affected factors. It was indicated that alpine meadow N2 O emission rates increased from 39.7 ± 3...
March 11, 2019: Current Microbiology
Futing Liu, Leiyi Chen, Beibei Zhang, Guanqin Wang, Shuqi Qin, Yuanhe Yang
Permafrost thaw could lead to frozen carbon (C) being laterally transferred to aquatic systems as dissolved organic carbon (DOC). If this part of DOC has high biodegradability, it could be decomposed during the delivery process, release greenhouse gases to the atmosphere and trigger positive C-climate feedback. Thermokarst is an abrupt permafrost thaw process that can enhance DOC export and also impact DOC processing through increased inorganic nitrogen (N) and ultraviolet (UV) light exposure. Especially on the Tibetan Plateau, where thermokarst develops widely and suffers from serious UV radiation and N limitation...
June 15, 2018: Science of the Total Environment
Yanan Cao, Jianshuang Wu, Xianzhou Zhang, Ben Niu, Meng Li, Yanjie Zhang, Xiangtao Wang, Zhipeng Wang
Forage-livestock balance is important for sustainable management of alpine grasslands under global change, but the robustness of diverse algorithms for assessing forage-livestock balance is still unclear. This study compiled long-term (2009-2014) field observations of aboveground biomass (AGB). Using climate and remote sensing data, we evaluated the inter-annual dynamics of the forage-livestock balance on the Northern Tibetan Plateau (NTP). Here, we assumed that AGB dynamics in fenced grasslands (AGBF ) is only driven by climate change; whereas AGB dynamics in open grasslands grazed by livestock (AGBG ) is driven by a combination of climate change and human activities...
March 8, 2019: Journal of Environmental Management
T Su, A Farnsworth, R A Spicer, J Huang, F-X Wu, J Liu, S-F Li, Y-W Xing, Y-J Huang, W-Y-D Deng, H Tang, C-L Xu, F Zhao, G Srivastava, P J Valdes, T Deng, Z-K Zhou
The Late Paleogene surface height and paleoenvironment for the core area of the Qinghai-Tibetan Plateau (QTP) remain critically unresolved. Here, we report the discovery of the youngest well-preserved fossil palm leaves from Tibet. They were recovered from the Late Paleogene (Chattian), ca. 25.5 ± 0.5 million years, paleolake sediments within the Lunpola Basin (32.033°N, 89.767°E), central QTP at a present elevation of 4655 m. The anatomy of palms renders them intrinsically susceptible to freezing, imposing upper bounds on their latitudinal and altitudinal distribution...
March 2019: Science Advances
Ping-Cuo Suolang, Bao-Qing Liu, Jing Chen, Ji De, Zha-Ba Nima, Ci-Ren Dunzhu
ETHNOPHARMACOLOGICAL RELEVANCE: Qiwei Tiexie capsule (QWTX) is a representative prescription of Tibetan medicine, which is widely used for long-term treatment of chronic liver disease and nonalcoholic fatty liver disease (NAFLD). AIM OF THE STUDY: This study explored the effects and mechanism of QWTX on 3T3-L1 adipocytes and NAFLD. MATERIALS AND METHODS: The 3T3-L1 preadipocytes and NAFLD rat model were used in the study. In 3T3-L1 cells, the cytotoxicity of QWTX was tested by CKK-8, and glucose uptake and fat acid oxidation were assessed by 2-deoxy-D-[3 H] glucose and [1-14 C] palmitic acid, respectively...
March 6, 2019: Journal of Ethnopharmacology
Jun Du, Kai Li, Zhibin He, Longfei Chen, Xi Zhu, Pengfei Lin
The trajectory of tree-growth response to climate warming may be related to attributes like tree age. However, age-mediation of temperature sensitivity of tree growth has received little attention. This study aimed to determine how age affects tree growth in a future warmer world. In a 2-year ecosystem warming experiment in the northeastern Tibetan Plateau of China, we explored the response of Qinghai spruce saplings at two life stages to two warming levels. Our results indicated a significant interaction between warming and age for sapling growth of Qinghai spruce...
February 2019: Ecology and Evolution
Haoxiang Zhang, Wenwen Gao, Lei Wang, Suzhen, Yanming Gao, Baoli Liu, Hao Zhou, Dianchun Fang
Objective: To investigate the prevalence and risk factors of gastroesophageal reflux disease (GERD) in the Tibet Autonomous Region, China. Methods: In this cross-sectional study, a stratified random sampling method was used for collecting samples in the Tibet Autonomous Region. A total of 10,000 individuals were selected from October 2016 to June 2017. A previously-published, validated questionnaire including six items related to the symptoms of GERD was used for evaluating GERD...
2019: PeerJ
C Sun, S Meng, R X Ye, Y J Wu, Q Z Wang, M Cao, H Zhou
In this study, 1 065 infants and young children aged 24 months below in ethnic minorities gathering in poor rural areas in poor rural areas of Liangshan Yi Autonomous Prefecture of Sichuan Province and Gannan Tibetan Autonomous Prefecture of Gansu Province were investigated for their anemia status from October to November 2014, and the association between anemia and the utilization of maternal and child health services was analyzed. The prevalence of anemia in this area was 52.68%(561/1 065). After the adjustment of socio-demographic characteristics of mothers and infants, compared with infants aged 2-5 months, Han ethnic group, and infants whose mother was not anemic, the OR (95 %CI ) values of infant anemia for infants aged 6-12 months, 13-8 months, 19-24 months, ethnic minorities group, and infants whose mother was anemic were 11...
March 6, 2019: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
W W Wang, X Jiang, B H Zheng, J Y Chen, L Zhao, B Zhang, S H Wang
The lakes distributed in the Tibetan Plateau constitute a lake group with the highest altitude, largest lakes and largest area in the world and are important in global climate and environmental effects. Freshwater lakes in the Tibetan Plateau possess high ecological values and high vulnerability. The migration and transformation of nitrogen in sediments are critical to lake ecosystems, but information on sedimentary nitrogen in the freshwater lakes in the Tibetan Plateau is limited. A case study was conducted in Keluke Lake, China, to reveal the effects of sedimentary nitrogen on water quality in plateau freshwater lakes...
September 2018: Royal Society Open Science
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