keyword
https://read.qxmd.com/read/37966309/the-relationship-between-manifestation-of-diabetes-insipidus-and-estimated-glomerular-filtration-rate-in-brain-death
#1
JOURNAL ARTICLE
Panayiotis N Varelas, Mohammed Kananeh, Paul Brady, Devin Holden, Chandan Mehta, Ashar Ata, Tamer Abdelhak, David Greer, Mohammed Rehman
OBJECTIVES: Systematic reviews have revealed that up to 50% of patients with brain death have residual hypothalamic/pituitary activity based on the absence of central diabetes insipidus (DI). We hypothesized that different degrees of renal dysfunction may impact the presence of DI in patients with brain death. DESIGN: Single-center prospective data collection. SETTING: ICUs in a tertiary academic hospital. PATIENTS: All adult patients declared brain dead over 12 years...
February 1, 2024: Critical Care Medicine
https://read.qxmd.com/read/36916346/-volume-management-of-intermittent-hemofiltration-guided-by-critical-care-ultrasound-in-the-treatment-of-acute-kidney-injury
#2
RANDOMIZED CONTROLLED TRIAL
Xiaoqiong Cui, Yongming Zou, Wenqing Gao, Huan Liu, Song Wang, Wei Wei, Yuanshen Song, Hao Wu
OBJECTIVE: To investigate the volume management of intermittent veno-venous hemofiltration (IVVH) guided by critical care ultrasound in the treatment of acute kidney injury (AKI) in patients with heart failure (HF). METHODS: A total of 216 patients with HF and AKI treated with IVVH in the coronary care unit (CCU) of the Third Central Hospital of Tianjin from April 2019 to June 2022 were selected as the study subjects, the patients were randomly divided into conventional guidance group (107 cases) and ultrasound guidance group (109 cases)...
March 2023: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/36630859/transient-diabetes-insipidus-in-critically-ill-covid19-patients
#3
REVIEW
Liran Statlender, Guy Fishman, Moran Hellerman, Ilya Kagan, Itai Bendavid, Dan Gorfil, Shani Kaptzon, Pierre Singer
PURPOSE: Vasopressin has become an important vasopressor drug while treating a critically ill patient to maintain adequate mean arterial pressure. Diabetes insipidus (DI) is a rare syndrome characterized by the excretion of a large volume of diluted urine, inappropriate for water homeostasis. We noticed that several COVID19 patients developed excessive polyuria suggestive of DI, with a concomitant plasma sodium-level increase and/or low urine osmolality. We noticed a temporal relationship between vasopressin treatment cessation and polyuria periods...
April 2023: Journal of Critical Care
https://read.qxmd.com/read/35094963/the-importance-of-terminology-for-quantifying-nocturia-in-practice
#4
JOURNAL ARTICLE
D Carolina Ochoa, Hashim Hashim
BACKGROUND: Although nocturia, affecting mainly the elderly population, is a urinary tract symptom, it may also be a part of conditions not related to the urinary tract. In this scenario, nocturia terminology is crucial to avoid confusion and misunderstanding across different specialities. The International Continence Society (ICS) provides the updated nocturia terminology. OBJECTIVE: To review, describe, and explain the applicability of nocturia terminology based on the ICS standardisation documents...
January 2022: European Urology Focus
https://read.qxmd.com/read/34478028/intravenous-milrinone-for-cerebral-vasospasm-in-subarachnoid-hemorrhage-the-milrispasm-controlled-before-after-study
#5
JOURNAL ARTICLE
Karim Lakhal, Antoine Hivert, Pierre-Louis Alexandre, Marion Fresco, Vincent Robert-Edan, Pierre-André Rodie-Talbere, Xavier Ambrosi, Romain Bourcier, Bertrand Rozec, Julien Cadiet
BACKGROUND: Intravenous (IV) milrinone, in combination with induced hypertension, has been proposed as a treatment option for cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH). However, data on its safety and efficacy are scarce. METHODS: This was a controlled observational study conducted in an academic hospital with prospectively and retrospectively collected data. Consecutive patients with cerebral vasospasm following aSAH and treated with both IV milrinone (0...
December 2021: Neurocritical Care
https://read.qxmd.com/read/34316180/acquired-bartter-like-syndrome-presenting-with-polyuria-and-reversible-hypokalemia-associated-with-colistin-use-in-a-critically-ill-pediatric-patient
#6
Damla P Yavas, Faruk Ekinci, Ozden O Horoz, Ozlem O Gundeslioglu, Bahriye Atmis, Dincer Yildizdas
We report a case of an acquired Bartter-like syndrome (BLS) after 3 days of treatment initiation and improved after discontinuation of colistin therapy in pediatric intensive care unit. A 2-month-old girl with spinal muscular atrophy type 1 who had respiratory distress received colistin therapy with a dose of 5 mg/kg/day for Acinetobacter baumannii complex isolation from endotracheal aspirate on the 12th day follow-up. Polyuria (6 mL/kg/hour) in the presence of normal blood pressure and hypokalemic metabolic alkalosis were developed on the 3rd day of colistin treatment...
July 2021: Indian Journal of Critical Care Medicine
https://read.qxmd.com/read/34016542/modern-management-of-and-update-on-prune-belly-syndrome
#7
REVIEW
Roberto I Lopes, Linda A Baker, Francisco T Dénes
Prune belly syndrome (PBS) is characterized by the triad of abdominal flaccidity, a variable degree of urinary tract involvement and cryptorchidism. Most cases of PBS are sporadic and have a normal karyotype, with 95% patients being male. In the last decade, mutations in known genes that regulate embryonic genitourinary myogenesis have been identified and with increasing knowledge of these critical genes involved in bladder maldevelopment, advances can be made in genetic counseling. A multidisciplinary approach is necessary and individualization of care is recommended according to phenotypic severity...
August 2021: Journal of Pediatric Urology
https://read.qxmd.com/read/33837022/perioperative-management-of-cranial-diabetes-insipidus-in-a-patient-requiring-a-tracheostomy
#8
JOURNAL ARTICLE
Mairead Kelly, Misha Verkerk, Patrick Harrison, Richard Oakley
Cranial diabetes insipidus (DI), which can cause life-threatening dehydration, is treated with desmopressin, often intranasally. This is challenging in patients whose nasal airflow is altered, such as those requiring tracheostomy. We report the case of a patient, taking intranasal desmopressin for cranial DI, who underwent partial glossectomy, free-flap reconstruction and tracheostomy. Postoperatively, she could not administer nasal desmopressin due to reduced nasal airflow. She developed uncontrollable thirst, polyuria and hypernatraemia...
April 9, 2021: BMJ Case Reports
https://read.qxmd.com/read/33644303/pediatric-emergency-medicine-didactics-and-simulation-pemdas-pediatric-diabetic-ketoacidosis
#9
JOURNAL ARTICLE
Cale Roberts, Ashley Keilman, Jean Pearce, Alissa Roberts, Kevin Ching, Jenny Kingsley, Alexander Stephan, Isabel Gross, Daisy Ciener, Julie Augenstein, Anita Thomas
Introduction: Diabetic ketoacidosis (DKA) is a life-threatening illness which classically presents with polyuria, polydipsia, and polyphagia that can rapidly progress to severe dehydration and altered mental status from cerebral edema. Younger patients may present with subtle or atypical symptoms that are critical to recognize and emergently act upon. Such patients are often cared for by teams in the emergency department (ED) requiring multidisciplinary collaboration. Methods: This simulation case was designed for pediatric emergency medicine fellows and residents...
February 17, 2021: MedEdPORTAL Publications
https://read.qxmd.com/read/32646670/central-diabetes-insipidus-in-children-diagnosis-and-management
#10
REVIEW
Giuseppa Patti, Anastasia Ibba, Giovanni Morana, Flavia Napoli, Daniela Fava, Natascia di Iorgi, Mohamad Maghnie
Central diabetes insipidus (CDI) is a complex disorder in which large volumes of dilute urine are excreted due to arginine-vasopressin deficiency, and it is caused by a variety of conditions (genetic, congenital, inflammatory, neoplastic, traumatic) that arise mainly from the hypothalamus. The differential diagnosis between diseases presenting with polyuria and polydipsia is challenging and requires a detailed medical history, physical examination, biochemical approach, imaging studies and, in some cases, histological confirmation...
September 2020: Best Practice & Research. Clinical Endocrinology & Metabolism
https://read.qxmd.com/read/31967010/protracted-acute-hypervolemic-hypernatremia-unmasked-after-vasopressin-therapy-case-report-literature-review-and-proposed-algorithmic-approach
#11
Michael Morkos, Maria Fam, Mishita Goel, Peter Hart, Rasa Kazlauskaite
Objective: Acute hypervolemic hypernatremia (HHN) is the most common form of hypernatremia in critical care settings. Previous reports implicated acute kidney injury and vasopressin withdrawal-induced central diabetes insipidus. Methods: We present the case of a 52-year-old woman who developed HHN after treatment of septic shock due to complicated bowel perforation. Results: After discontinuation of a 30-hour infusion of vasopressin analog, the patient manifested hypernatremia (150 to 156 mEq/L, equivalent to mmol/L) with hyponatriuria (49 mEq/L), hypoosmotic urine (163 mOsm/L), and polyuria (6...
March 2019: AACE Clinical Case Reports
https://read.qxmd.com/read/31423144/the-ability-of-polyuria-in-prediction-of-weaning-outcome-in-critically-ill-mechanically-ventilated-patients
#12
JOURNAL ARTICLE
Masoud Aliyali, Ali Sharifpour, Siavash Abedi, Fatemeh Spahbodi, Narges Namarian, Adel Zarea, Ahad Alizadeh
BACKGROUND: Fluid balance and oliguria influence outcome in critically ill patients. Although, osmotic dieresis with hypernatraemia is a predictor of mortality in critically ill patients, the purpose of this study was to demonstrate the effect of polyuria as an independent predictor on weaning outcome in mechanically ventilated patients. MATERIALS AND METHODS: This retrospective, single center, cohort study was carried out at Imam Teaching Hospital Intensive Care Unit (ICU) on 263 adult mechanically ventilated patients...
January 2019: Tanaffos
https://read.qxmd.com/read/30784603/diabetes-insipidus-and-syndrome-of-inappropriate-antidiuretic-hormone-in-critically-ill-patients
#13
REVIEW
Anatole Harrois, James R Anstey
Diabetes insipidus and the syndrome of inappropriate antidiuretic hormone secretion lie at opposite ends of the spectrum of disordered renal handling of water. Whereas renal retention of water insidiously causes hypotonic hyponatremia in syndrome of inappropriate antidiuretic hormone secretion, diabetes insipidus may lead to free water loss, hypernatremia, and volume depletion. Hypernatremia and hyponatremia are associated with worse outcomes and longer intensive care stays. Moreover, pathologies causing polyuria and hyponatremia in patients in intensive care may be multiple, making diagnosis challenging...
April 2019: Critical Care Clinics
https://read.qxmd.com/read/30571823/clinical-profile-of-children-with-diabetic-ketoacidosis-in-fifteen-years-of-management-in-a-critical-care-unit
#14
JOURNAL ARTICLE
Paulina Del Pozo, Diego Aránguiz, Guiliana Córdova, Christian Scheu, Patricio Valle, Jaime Cerda, Hernán García, María Isabel Hodgson, Andrés Castillo
INTRODUCTION: Diabetic ketoacidosis (DKA) is the main cause of morbidity and mortality in children with type 1 diabetes mellitus (T1DM) due to clinical and biochemical alterations associated, cerebral edema as one of the most critical because of the high mortality rates and long-term neurological se quelae. OBJECTIVE: To analyze the clinical characteristics and complications of patients with DKA ad mitted to a pediatric intensive care unit. PATIENTS AND METHODS: Retrospective study of DKA patients treated at the Hospital Clínico, Pontificia Universidad Católica de Chile (UPCPUC) between 2000 and 2015...
August 2018: Revista Chilena de Pediatría
https://read.qxmd.com/read/30158258/siadh-and-water-intoxication-related-to-ecstasy
#15
JOURNAL ARTICLE
Cecile Salathe, Anne-Laure Blanc, Damien Tagan
Recreational drug use is a significant societal issue and remains a clinical challenge in emergency and critical care departments. We report on a 19-year-old woman admitted to hospital semiconscious and with severe hyponatraemia. Urinalysis was positive for methamphetamine and supported a diagnosis of hyponatraemia related to ecstasy use together with a syndrome of inappropriate antidiuretic hormone secretion (SIADH). The woman was transferred to an intensive care unit, where a hypertonic saline infusion was started...
August 29, 2018: BMJ Case Reports
https://read.qxmd.com/read/29217500/peripheral-neuropathy-as-a-complication-of-diabetic-ketoacidosis-in-a-child-with-newly-diagnosed-diabetes-type-1-a-case-report
#16
JOURNAL ARTICLE
Marta Baszyńska-Wilk, Marta Wysocka-Mincewicz, Anna Świercz, Jolanta Świderska, Magdalena Marszał, Mieczysław Szalecki
Neurological complications of diabetic ketoacidosis are considered to be a serious clinical problem. The most common complication is cerebral edema. However, these neurological complications also include less common entities such as ischemic or hemorrhagic stroke, cerebral venous and sinus thrombosis or peripheral neuropathy. We present a case of a 9-year old girl admitted to our intensive care unit with new onset type 1 diabetes, diabetic ketoacidosis, cerebral edema, multifocal vasogenic brain lesions and bilateral lower limb peripheral paresis...
July 31, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://read.qxmd.com/read/28530380/diabetes-update-primary-care-of-patients-with-type-1-diabetes
#17
REVIEW
Beth Choby
The incidence and prevalence of type 1 diabetes (T1D) are increasing among white, black, Hispanic, and Asian individuals in the United States. Children often present with acute symptoms, including severe polyuria, polydipsia, weight loss, and ketonemia; adults may develop more gradual symptoms that initially appear similar to those of type 2 diabetes (T2D). Latent autoimmune diabetes of adults and maturity-onset diabetes of the young are conditions that may be confused with T1D, although they are actually more closely related to T2D...
May 2017: FP Essentials
https://read.qxmd.com/read/27414478/partial-nephrogenic-diabetes-insipidus-in-a-burned-patient-receiving-sevoflurane-sedation-with-an-anesthetic-conserving-device-a-case-report
#18
JOURNAL ARTICLE
Marie Muyldermans, Serge Jennes, Stuart Morrison, Olivier Soete, Pierre-Michel François, Elkana Keersebilck, Thomas Rose, Olivier Pantet
OBJECTIVE: To describe a case of partial nephrogenic diabetes insipidus in a burned patient after prolonged delivery of low inspired concentrations of sevoflurane via an Anesthetic Conserving Device. DATA SOURCES: Clinical observation. STUDY SELECTION: Case report. DATA EXTRACTION: Relevant clinical information. DATA SYNTHESIS: A 34-year-old man was admitted with burns covering 52% of his total body surface area...
December 2016: Critical Care Medicine
https://read.qxmd.com/read/26812288/cerebral-salt-wasting-in-pediatric-critical-care-not-just-a-neurosurgical-disorder-anymore
#19
JOURNAL ARTICLE
Orkun Tolunay, Tamer Celik, Umit Celik, Mustafa Kömür, Begul Yagci-Kupeli
OBJECTIVE: Cerebral salt-wasting syndrome (CSWS) is a hypovolemic hyponatremia caused by natriuresis and diuresis, of which the exact pathogenesis is unknown. Although CSWS has been more commonly described to be associated with neurosurgical disorders, increasing numbers of patients are diagnosed and new etiological factors are being identified as the awareness of it increases. METHODS: The files of the patients who had been hospitalized and treated with the diagnosis of CSWS at the pediatric critical care unit during the last three years were retrospectively reviewed...
December 2015: Neuro Endocrinology Letters
https://read.qxmd.com/read/26402577/polyuria-in-relation-to-dysnatraemias-in-neurocritical-care
#20
JOURNAL ARTICLE
Vera Spatenkova, Ondrej Bradac, Patricia de Lacy, Pavel Skrabalek
INTRODUCTION: Polyuria has the potential to cause severe water and sodium imbalance. We studied the epidemiology of polyuria in association with dysnatraemias and whether polyuria is an independent risk factor for higher mortality and poorer outcome in neurocritical care. METHODS: We performed an analysis of a 3-year prospective database containing 902 neurocritical care patients. Polyuria was defined as diuresis above 4000 ml/day, hyponatraemia as a serum sodium (SeNa) < 135 mmol/l and hypernatraemia as SeNa > 150 mmol/l...
2015: British Journal of Neurosurgery
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