Giuseppa Patti, Anastasia Ibba, Giovanni Morana, Flavia Napoli, Daniela Fava, Natascia di Iorgi, Mohamad Maghnie
Central diabetes insipidus (CDI) is a complex disorder in which large volumes of dilute urine are excreted due to arginine-vasopressin deficiency, and it is caused by a variety of conditions (genetic, congenital, inflammatory, neoplastic, traumatic) that arise mainly from the hypothalamus. The differential diagnosis between diseases presenting with polyuria and polydipsia is challenging and requires a detailed medical history, physical examination, biochemical approach, imaging studies and, in some cases, histological confirmation...
September 2020: Best Practice & Research. Clinical Endocrinology & Metabolism