Matthias Kohlhauer, Fanny Lidouren, Isabelle Remy-Jouet, Nicolas Mongardon, Clovis Adam, Patrick Bruneval, Hakim Hocini, Yves Levy, Fabiola Blengio, Pierre Carli, Benoit Vivien, Jean-Damien Ricard, Philippe Micheau, Hervé Walti, Mathieu Nadeau, Raymond Robert, Vincent Richard, Paul Mulder, David Maresca, Charlie Demené, Mathieu Pernot, Mickael Tanter, Bijan Ghaleh, Alain Berdeaux, Renaud Tissier
OBJECTIVES: Total liquid ventilation provides ultrafast and potently neuro- and cardioprotective cooling after shockable cardiac arrest and myocardial infarction in animals. Our goal was to decipher the effect of hypothermic total liquid ventilation on the systemic and cerebral response to asphyxial cardiac arrest using an original pressure- and volume-controlled ventilation strategy in rabbits. DESIGN: Randomized animal study. SETTING: Academic research laboratory...
October 2015: Critical Care Medicine