Armelle Guénégou-Arnoux, Juliette Murris, Stéphane Bechet, Camille Jung, Johann Auchabie, Julien Dupeyrat, Nadia Anguel, Pierre Asfar, Julio Badie, Dorothée Carpentier, Benjamin Chousterman, Jeremy Bourenne, Agathe Delbove, Jérôme Devaquet, Nicolas Deye, Guillaume Dumas, Anne-Florence Dureau, Jean-Baptiste Lascarrou, Stephane Legriel, Christophe Guitton, Caroline Jannière-Nartey, Jean-Pierre Quenot, Jean-Claude Lacherade, Julien Maizel, Armand Mekontso Dessap, Bruno Mourvillier, Philippe Petua, Gaetan Plantefeve, Jean-Christophe Richard, Alexandre Robert, Clément Saccheri, Ly Van Phach Vong, Sandrine Katsahian, Frédérique Schortgen
INTRODUCTION: Fever treatment is commonly applied in patients with sepsis but its impact on survival remains undetermined. Patients with respiratory and haemodynamic failure are at the highest risk for not tolerating the metabolic cost of fever. However, fever can help to control infection. Treating fever with paracetamol has been shown to be less effective than cooling. In the SEPSISCOOL pilot study, active fever control by external cooling improved organ failure recovery and early survival...
January 29, 2024: BMJ Open