keyword
https://read.qxmd.com/read/38534816/a-bio-inspired-approach-to-improve-the-toughness-of-brittle-bast-fibre-reinforced-composites-using-cellulose-acetate-foils
#1
JOURNAL ARTICLE
Nina Graupner, Jörg Müssig
Bast fibre-reinforced plastics are characterised by good strength and stiffness but are often brittle due to the stiff and less ductile fibres. This study uses a biomimetic approach to improve impact strength. Based on the structure of the spicules of a deep-sea glass sponge, in which hard layers of bioglass alternate with soft layers of proteins, the toughness of kenaf/epoxy composites was significantly improved by a multilayer structure of kenaf and cellulose acetate (CA) foils as impact modifiers. Due to the alternating structure, cracks are deflected, and toughness is improved...
February 21, 2024: Biomimetics
https://read.qxmd.com/read/38532882/bioglass-ceria-nanoparticle-hybrids-for-the-treatment-of-seroma-a-comparative-long-term-study-in-rats
#2
JOURNAL ARTICLE
Michael-Alexander Pais, Athanasios Papanikolaou, Isabel Arenas Hoyos, Robert Nißler, Simone De Brot, Alexander Gogos, Robert Rieben, Mihai A Constantinescu, Martin T Matter, Inge K Herrmann, Ioana Lese
Background: Seroma formation is a common postoperative complication. Fibrin-based glues are typically employed in an attempt to seal the cavity. Recently, the first nanoparticle (NP)-based treatment approaches have emerged. Nanoparticle dispersions can be used as tissue glues, capitalizing on a phenomenon known as 'nanobridging'. In this process, macromolecules such as proteins physically adsorb onto the NP surface, leading to macroscopic adhesion. Although significant early seroma reduction has been shown, little is known about long-term efficacy of NPs...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38526676/bone-formation-by-irisin-poly-vinyl-alchol-modified-bioglass-ceramic-beads-in-the-rabbit-model
#3
JOURNAL ARTICLE
Seong-Su Park, Ume Farwa, Hai-Doo Kim, Yong-Sik Kim, Byong-Taek Lee
In the aging society, slow bone regeneration poses a serious hindrance to the quality of life. To deal with this problem, in this study, we have combined irisin with the bioglass regular beads to enhance the bone regeneration process. For this purpose, highly porous bioglass was obtained as spherical beads by using sodium alginate. The bioglass was evaluated by various analytical techniques such as SEM, EDS, XRD, and pore size distribution. The results depicted that porous bioglass was prepared correctly and SEM analysis showed a highly porous bioglass was formulated...
March 25, 2024: Journal of Materials Science. Materials in Medicine
https://read.qxmd.com/read/38516930/an-integrative-biology-approach-to-understanding-keratinocyte-collective-migration-as-stimulated-by-bioglass
#4
JOURNAL ARTICLE
Joseph Siegfreid, Ali Crampton, Saghi Saghazadeh, Randilynn Christensen, Jacob Notbohm, Jason Bjork, Bryan Baker
A critical phase of wound healing is the coordinated movement of keratinocytes. To this end, bioglasses show promise in speeding healing in hard tissues and skin wounds. Studies suggest that bioglass materials may promote wound healing by inducing positive cell responses in proliferation, growth factor production, expression of angiogenic factors, and migration. Precise details of how bioglass may stimulate migration are unclear, however, because the common assays for studying migration in wound healing focus on simplified outputs like rate of migration or total change in wound area...
January 23, 2024: Integrative Biology: Quantitative Biosciences From Nano to Macro
https://read.qxmd.com/read/38512116/enhancement-in-the-induction-heating-efficacy-of-sol-gel-derived-sio-2-cao-na-2-o-p-2-o-5-bioglass-ceramics-by-incorporating-magnetite-nanoparticles
#5
JOURNAL ARTICLE
Nitu, Rushikesh Fopase, Lalit Mohan Pandey, Krishna Priya Hazarika, Jyoti Prasad Borah, Rajendra K Singh, Ananthakrishnan Srinivasan
Magnetite (Fe3 O4 ) nanoparticle (MNP)-substituted glass-ceramic (MSGC) powders with compositions of (45 - x )SiO2 -24.5CaO-24.5Na2 O-6P2 O5 - x Fe3 O4 ( x = 5, 8, and 10 wt%) have been prepared by a sol-gel route by introducing Fe3 O4 nanoparticles during the synthesis. The X-ray diffraction patterns of the as-prepared MSGC nanopowders revealed the presence of combeite (Na2 Ca2 Si3 O9 ), magnetite, and sodium nitrate (NaNO3 ) crystalline phases. Heat-treatment up to 700 °C for 1 h resulted in the complete dissolution of NaNO3 along with partial conversion of magnetite into hematite (α-Fe2 O3 )...
March 21, 2024: Journal of Materials Chemistry. B, Materials for Biology and Medicine
https://read.qxmd.com/read/38392745/in-vitro-modulation-of-spontaneous-activity-in-embryonic-cardiomyocytes-cultured-on-poly-vinyl-alcohol-bioglass-type-58s-electrospun-scaffolds
#6
JOURNAL ARTICLE
Filiberto Rivera-Torres, Alfredo Maciel-Cerda, Gertrudis Hortensia González-Gómez, Alicia Falcón-Neri, Karla Gómez-Lizárraga, Héctor Tomás Esquivel-Posadas, Ricardo Vera-Graziano
Because of the physiological and cardiac changes associated with cardiovascular disease, tissue engineering can potentially restore the biological functions of cardiac tissue through the fabrication of scaffolds. In the present study, hybrid nanofiber scaffolds of poly (vinyl alcohol) (PVA) and bioglass type 58S (58SiO2 -33CaO-9P2 O5 , Bg) were fabricated, and their effect on the spontaneous activity of chick embryonic cardiomyocytes in vitro was determined. PVA/Bg nanofibers were produced by electrospinning and stabilized by chemical crosslinking with glutaraldehyde...
February 17, 2024: Nanomaterials
https://read.qxmd.com/read/38391458/chitosan-and-sodium-hyaluronate-hydrogels-supplemented-with-bioglass-for-bone-tissue-engineering
#7
JOURNAL ARTICLE
Lidia Ciołek, Ewa Zaczyńska, Małgorzata Krok-Borkowicz, Monika Biernat, Elżbieta Pamuła
The aim of the study was to produce biocomposites based on chitosan and sodium hyaluronate hydrogels supplemented with bioglasses obtained under different conditions (temperature, time) and to perform an in vitro evaluation of their cytocompatibility using both indirect and direct methods. Furthermore, the release of ions from the composites and the microstructure of the biocomposites before and after incubation in simulated body fluid were assessed. Tests on extracts from bioglasses and hydrogel biocomposites were performed on A549 epithelial cells, while MG63 osteoblast-like cells were tested in direct contact with the developed biomaterials...
February 5, 2024: Gels
https://read.qxmd.com/read/38387060/ecofriendly-and-scalable-production-of-bioglass-using-an-organic-calcium-source-enhanced-bioactivity-for-tissue-repair
#8
JOURNAL ARTICLE
Yun Chen, Fang Hu, Chuangzhou Guo, Xihua Dong, Hai Wang, Yue Qin
The eco-friendly and scalable production of bioglass remains a challenging but attractive strategy for advancing its widespread biomedical applications. Although the sol-gel method has been considered a valuable approach for bioglass production, the application of calcium nitrate as a calcium source markedly limits its industrialization owing to environmental pollution, high administration costs, and numerous calcium-rich regions in the as-prepared bioglass. Therefore, organic Ca has been proposed as an alternative to inorganic Ca...
February 22, 2024: Biomedical Materials
https://read.qxmd.com/read/38387057/eco-friendly-synthesis-of-mesoporous-bioactive-glass-ceramics-and-functionalization-for-drug-delivery-and-hard-tissue-engineering-applications
#9
JOURNAL ARTICLE
Sobia Tabassum, Muhammad Saqib, Madeeha Batool, Faiza Sharif, Mazhar Amjad Gilani, Olivier Huck
Hard tissue regenerative mesoporous bioactive glass (MBG) has traditionally been synthesized using costly and toxic alkoxysilane agents and harsh conditions. In this study, MBG was synthesized using the cheaper reagent SiO2 by using a co-precipitation approach. The surface properties of MBG ceramic were tailored by functionalizing with amino and carboxylic groups, aiming to develop an efficient drug delivery system for treating bone infections occurring during or after reconstruction surgeries. The amino groups were introduced through a salinization reaction, while the carboxylate groups were added via a chain elongation reaction...
February 22, 2024: Biomedical Materials
https://read.qxmd.com/read/38371771/oral-release-kinetics-biodistribution-and-excretion-of-dopants-from-barium-containing-bioactive-glass-in-rats
#10
JOURNAL ARTICLE
Shreyasi Majumdar, Anshul Tiwari, Debasmit Mallick, Devendra K Patel, Surendra Kumar Trigun, Sairam Krishnamurthy
Background : Inorganic biomaterials are biologically active and are used as implants and drug delivery system. They have therapeutically active elements present in their framework that are released in the physiological milieu. Release of these dopants above the supraphysiological limit may produce adverse effects and physicochemical interactions with the loaded drugs. Therefore, this necessitates evaluating the in vivo release kinetics, biodistribution, and excretion profiles of dopants from barium-doped bioglass (BaBG) that has potential anti-inflammatory, antiulcer, and regenerative properties...
February 13, 2024: ACS Omega
https://read.qxmd.com/read/38348496/development-characterization-and-biological-study-of-bioglass-coatings-45s5-and-biok-on-zirconia-implant-surfaces
#11
JOURNAL ARTICLE
Sarah de Oliveira Marco Avelino, Leonardo Alvares Sobral-Silva, Gilmar Patrocínio Thim, Luis Augusto de Almeida-Silva, Juliana Dos Santos Lupp, Tiago Moreira Bastos Campos, Luana Marotta Reis de Vasconcellos
Zirconia implants are gaining attention as a viable alternative to titanium implants due to their comparable osseointegration development, improved soft tissue adaptation, and enhanced aesthetics. An encouraging avenue for improving zirconia implant properties involves the potential application of bioactive coatings to their surfaces. These coatings have shown potential for inducing hydroxyapatite formation, crucial for bone proliferation, and improving implant mechanical properties. This study aimed to evaluate the effect of coating zirconia implants with two bioactive glasses, 45S5 and BioK, on osteogenesis in vitro and osseointegration in vivo...
February 2024: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://read.qxmd.com/read/38342258/multi-functional-bandage-bioactive-glass-metal-oxides-alginate-composites-based-regenerative-membrane-facilitating-re-epithelialization-in-diabetic-wounds-with-sustained-drug-delivery-and-anti-bactericidal-efficacy
#12
JOURNAL ARTICLE
P Bargavi, S Balakumar, S Raghunandhakumar
Chronic wounds, especially diabetic, foot and pressure ulcers are a major health problem affecting >10 % of the world's populace. Calcium phosphate materials, particularly, bioactive glasses (BG), used as a potential material for hard and soft tissue repair. This study combines nanostructured 45S5 BG with titania (TiO2 ) and alumina (Al2 O3 ) into a composite via simple sol-gel method. Prepared composites with alginate (Alg) formed a bioactive nanocomposite hydrogel membrane via freezing method. X-ray diffraction revealed formation of two phases such as Na1...
February 9, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38323923/final-irrigation-with-bioglass-solution-in-regenerative-endodontic-procedure-induces-tissue-formation-inside-the-root-canals-collagen-maturation-proliferation-cell-and-presence-of-osteocalcin
#13
JOURNAL ARTICLE
Kiani Dos Santos de Paula, Alexandre Henrique Dos Reis-Prado, Witalo Pereira de Jesus, Juliana Goto, Lara Cancella de Arantes, Marina Verçosa, Luciano Tavares Angelo Cintra, Edilson Ervolino, Raphael Escorsim Szawka, Murilo Camuri Crovace, Ricardo Alves de Mesquita, Francine Benetti
AIM: To evaluate the influence of an experimental solution of cobalt-doped F18 bioactive glass (F18Co) on tissue repair following regenerative endodontic procedure (REP) in rat molars. METHODOLOGY: The F18Co solution was prepared at a ratio of 1:5 F18Co powder to distilled water. The right or left upper first molars of 12 Wistar rats were used, where the pulps were exposed, removed, and irrigated with 2.5% sodium hypochlorite (NaOCl), followed by 17% ethylenediaminetetraacetic acid (EDTA) (5 min each)...
February 7, 2024: International Endodontic Journal
https://read.qxmd.com/read/38276437/influence-of-the-addition-of-zinc-strontium-or-magnesium-oxides-to-the-bioglass-45s5-network-on-electrical-behavior
#14
JOURNAL ARTICLE
Sílvia Rodrigues Gavinho, Imen Hammami, Suresh Kumar Jakka, Sílvia Soreto Teixeira, Jorge Carvalho Silva, João Paulo Borges, Manuel Pedro Fernandes Graça
45S5 Bioglass has been widely used in regenerative medicine due to its ability to dissolve when inserted into the body. Its typically amorphous structure allows for an ideal dissolution rate for the formation of the hydroxyapatite layer, which is important for the development of new bone. This bioactive capacity can also be controlled by adding other oxides (e.g., SrO, ZnO, and MgO) to the 45S5 Bioglass network or by storing electrical charge. Ions such as zinc, magnesium, and strontium allow for specific biological responses to be added, such as antibacterial action and the ability to increase the rate of osteoblast proliferation...
January 20, 2024: Materials
https://read.qxmd.com/read/38274939/fabrication-and-characterization-of-an-innovative-silver-and-gadolinium-doped-bioglass-for-bone-regeneration
#15
JOURNAL ARTICLE
Hari Vamsh Korukonda, Nidhita Suresh, Saranya K
Background Periodontal regeneration aims for the three-dimensional reconstruction of bone defects, and over the years, bone grafts with or without barrier membranes have provided us with promising results. Particulate bone grafts can be classified according to the source of procurement as autografts, allografts, xenografts, and alloplasts. Bioglass, an innovative alloplast that uses silica particles as a matrix incorporated with calcium and phosphorus, has been extensively used as a propitious material for bone regeneration owing to its inherent osteogenic ability and biocompatibility but presents with various disadvantages such as slow degradation rate, low mechanical strength, and fracture resistance...
December 2023: Curēus
https://read.qxmd.com/read/38258050/tunable-release-of-calcium-from-chitosan-coated-bioglass
#16
JOURNAL ARTICLE
Vuk Uskoković, Gabriel Abuna, Joseph Ryan Hampton, Saulo Geraldeli
Bioglass presents a standard biomaterial for regeneration of hard tissues in orthopedics and dentistry. The notable osteo-inductive properties of bioglass are largely due to the release of calcium ions from it. However, this release is not easily controllable and can often be excessive, especially during the initial interaction of the biomaterial with the surrounding tissues. Consequently, this excessive release can deplete the calcium content of the bioglass, ultimately reducing its overall bioactivity. In this study, we have tested if applying biopolymer chitosan coatings of different thicknesses would be able to mitigate and regulate the calcium ion release from monodisperse bioglass nanoparticles...
December 27, 2023: Pharmaceutics
https://read.qxmd.com/read/38231946/synthesis-of-poly-ethylene-furanoate-based-nanocomposites-by-in-situ-polymerization-with-enhanced-antibacterial-properties-for-food-packaging-applications
#17
JOURNAL ARTICLE
Johan Stanley, Eleftheria Xanthopoulou, Matjaž Finšgar, Lidija Fras Zemljič, Panagiotis A Klonos, Apostolos Kyritsis, Savvas Koltsakidis, Dimitrios Tzetzis, Dimitra A Lambropoulou, Diana Baciu, Theodore A Steriotis, Georgia Charalambopoulou, Dimitrios N Bikiaris
Poly(ethylene 2,5-furandicarboxylate) (PEF)-based nanocomposites containing Ce-bioglass, ZnO, and ZrO2 nanoparticles were synthesized via in situ polymerization, targeting food packaging applications. The nanocomposites were thoroughly characterized, combining a range of techniques. The successful polymerization was confirmed using attenuated total reflectance Fourier-transform infrared (ATR-FTIR) spectroscopy, and the molecular weight values were determined indirectly by applying intrinsic viscosity measurements...
November 23, 2023: Polymers
https://read.qxmd.com/read/38201731/poly-%C3%AE%C2%B5-caprolactone-3d-printed-porous-scaffold-in-a-femoral-condyle-defect-model-induces-early-osteo-regeneration
#18
JOURNAL ARTICLE
Arianna De Mori, Aikaterina Karali, Evangelos Daskalakis, Richard Hing, Paulo Jorge Da Silva Bartolo, Glen Cooper, Gordon Blunn
Large bone reconstruction following trauma poses significant challenges for reconstructive surgeons, leading to a healthcare burden for health systems, long-term pain for patients, and complex disorders such as infections that are difficult to resolve. The use of bone substitutes is suboptimal for substantial bone loss, as they induce localized atrophy and are generally weak, and unable to support load. A combination of strong polycaprolactone (PCL)-based scaffolds, with an average channel size of 330 µm, enriched with 20% w / w of hydroxyapatite (HA), β-tricalcium phosphate (TCP), or Bioglass 45S5 (Bioglass), has been developed and tested for bone regeneration in a critical-size ovine femoral condyle defect model...
December 24, 2023: Polymers
https://read.qxmd.com/read/38188644/3d-bioprinting-bioglass-to-construct-vascularized-full-thickness-skin-substitutes-for-wound-healing
#19
JOURNAL ARTICLE
Yanyan Liu, Xin Liu, Haitao Guo, Xinhuan Wang, Ailing Li, Dong Qiu, Qi Gu
Constructing three-dimensional (3D) bioprinted skin tissues that accurately replicate the mechanical properties of native skin and provide adequate oxygen and nutrient support remains a formidable challenge. In this study, we incorporated phosphosilicate calcium bioglasses (PSCs), a type of bioactive glass (BG), into the bioinks used for 3D bioprinting. The resulting bioink exhibited mechanical properties and biocompatibility that closely resembled those of natural skin. Utilizing 3D bioprinting technology, we successfully fabricated full-thickness skin substitutes, which underwent comprehensive evaluation to assess their regenerative potential in treating full-thickness skin injuries in rats...
February 2024: Materials today. Bio
https://read.qxmd.com/read/38171654/multi-crosslinked-hydrogel-built-with-hyaluronic-acid-tyramine-thiolated-glycol-chitosan-and-copper-doped-bioglass-nanoparticles-for-expediting-wound-healing
#20
JOURNAL ARTICLE
Yifeng Yu, Congcong Wang, Qiaoqin Fu, Ying Wan, Aixi Yu
The migration of fibroblasts and endothelial cells is a critical determinant of wound-healing outcomes for skin injuries. Here, hyaluronic acid-tyramine (HAT) and thiolated glycol chitosan (TGC) conjugates were combined with copper-doped bioglass (ACuBG) nanoparticles to build a novel type of multi-crosslinked hydrogel for stimulating the migration of cells, and thus, expediting wound healing. The optimally devised HAT/TGC/ACuBG gels had markedly improved strength and stiffness compared to the gels built from either HAT or TGC while showing sufficient elasticity, which contributes to stimulating the migration of fibroblasts...
March 1, 2024: Carbohydrate Polymers
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