keyword
https://read.qxmd.com/read/38536227/patient-education-and-decision-support-for-long-acting-injectable-hiv-antiretroviral-therapy-protocol-for-tool-development-and-pilot-testing-with-ryan-white-hiv-aids-program-medical-case-management-programs-in-new-york
#1
JOURNAL ARTICLE
Mary Kathryn Irvine, Rebecca Zimba, Tigran Avoundjian, Meghan Peterson, Connor Emmert, Sarah G Kulkarni, Morgan M Philbin, Elizabeth A Kelvin, Denis Nash
BACKGROUND: Long-acting injectable (LAI) HIV antiretroviral therapy (ART) presents a major opportunity to facilitate and sustain HIV viral suppression, thus improving health and survival among people living with HIV and reducing the risk of onward transmission. However, realizing the public health potential of LAI ART requires reaching patients who face barriers to daily oral ART adherence and thus can clinically benefit from alternative treatment modalities. Ryan White HIV/AIDS Program Part A medical case management (MCM) programs provide an array of services to address barriers to HIV care and treatment among economically and socially marginalized people living with HIV...
March 27, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38526967/association-of-neighbourhood-walkability-and-haemoglobin-a1c-levels-among-latino-and-non-hispanic-white-patients-with-diabetes
#2
JOURNAL ARTICLE
Jennifer A Lucas, Miguel Marino, Sophia Giebultowicz, Dang Dinh, Roopradha Datta, David Boston, John Heintzman
BACKGROUND: Neighbourhood walkability can benefit cardiovascular health. Latino patients are more likely than non-Hispanic White patients to have diabetes, and evidence has shown better diabetes-related outcomes for patients living in neighbourhoods conducive to physical activity. Our objective was to determine whether neighbourhood walkability was associated with haemoglobin A1c (HbA1c) levels among English- and Spanish-preferring Latino patients compared to non-Hispanic White patients...
March 25, 2024: Family Practice
https://read.qxmd.com/read/38526741/working-memory-load-modulates-anticipatory-postural-adjustments-during-step-initiation
#3
JOURNAL ARTICLE
Kodai Minami, Eiji Yamanaka, Kohei Okuyama, Michiyuki Kawakami, Kunitsugu Kondo, Riku Ishizaka, Aoki Takahashi, Tatsunori Watanabe
Working memory (WM) can influence selective attention. However, the effect of WM load on postural standing tasks has been poorly understood, even though these tasks require attentional resources. The purpose of this study was to examine whether WM load would impact anticipatory postural adjustments (APAs) during step initiation. Sixteen healthy young adults performed stepping tasks alone or concurrently with a WM task in a dual-task design. The stepping tasks involved volitional stepping movements in response to visual stimuli and comprised of simple and choice reaction time tasks and the Flanker task which consisted of congruent and incongruent (INC) conditions...
March 25, 2024: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/38526247/3d-printed-lung-phantom-for-individual-monitoring
#4
JOURNAL ARTICLE
Kevin Capello, Marilyn Tremblay, Aryanna Schiebelbein, Noah Janzen
The Human Monitoring Laboratory, Health Canada (HML), has used a 3D printer to re-engineer its Lawrence Livermore National Laboratory (LLNL) foam lung sets (manufactured by Radiology Support Devices, Inc., Long Beach, CA). The foam sets are currently the HML standard for calibrating and performance testing lung-counting systems in Canada. This paper describes the process of creating and validating new 3D-printed lung sets modeled from one of the HML's existing RSD foam sets. The existing sets were custom made, making them costly and difficult to obtain or replace...
May 1, 2024: Health Physics
https://read.qxmd.com/read/38523046/development-of-an-antimicrobial-3d-printable-denture-base-material-with-k18-quaternary-ammonium-silane-functionalized-methyl-methacrylate-and-filler
#5
JOURNAL ARTICLE
Mansi Patel, Leslie Barrera, Lianrui Chu, Kyumin Whang
STATEMENT OF PROBLEM: Denture base materials are highly susceptible to microbial colonization, which can lead to denture stomatitis. In addition, patients who sleep with their dentures have an increased chance of contracting pneumonia. Commercially available antimicrobial denture base materials to prevent or combat microbial colonization are lacking. PURPOSE: The purpose of this in vitro study was to determine the effects of K18 quaternary ammonium methacryloxy silane-functionalized filler (K18-Filler) and methyl methacrylate (K18-MMA) on the polymerization of 3D printed denture base material and its esthetic, mechanical, and antimicrobial properties...
March 23, 2024: Journal of Prosthetic Dentistry
https://read.qxmd.com/read/38519739/trabecular-bone-mineral-density-as-measured-by-thoracic-vertebrae-predicts-incident-hip-and-vertebral-fractures-the-multi-ethnic-study-of-atherosclerosis
#6
JOURNAL ARTICLE
Dong Li, Song Shou Mao, Matthew J Budoff
UNLABELLED: We evaluated the relationship of bone mineral density (BMD) by computed tomography (CT), to predict fractures in a multi-ethnic population. We demonstrated that vertebral and hip fractures were more likely in those patients with low BMD. This is one of the first studies to demonstrate that CT BMD derived from thoracic vertebrae can predict future hip and vertebral fractures. PURPOSE/INTRODUCTION: Osteoporosis affects an enormous number of patients, of all races and both sexes, and its prevalence increases as the population ages...
March 22, 2024: Osteoporosis International
https://read.qxmd.com/read/38512730/the-heel-complex-anatomy-imaging-pathologic-conditions-and-treatment
#7
JOURNAL ARTICLE
Dyan V Flores, Paola Kuenzer Goes, Alameen Damer, Brady K Huang
The differential diagnosis for heel pain is broad but primarily involves abnormalities of the Achilles tendon, calcaneus, and plantar fascia. Achilles tendon disorders include tendinosis, tendinitis, and partial or complete tears. Tendinosis refers to tendon degeneration, while tendinitis is inflammation after acute overload. Untreated tendinosis can progress to partial or complete tears. Tendon disorders can be accompanied by paratenonitis or inflammation of the loose sheath enclosing the tendon. Initial management involves rehabilitation and image-guided procedures...
April 2024: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://read.qxmd.com/read/38512728/imaging-features-of-arrhythmogenic-cardiomyopathies
#8
JOURNAL ARTICLE
Mauricio S Galizia, Anil K Attili, William R Truesdell, Eric D Smith, Adam S Helms, Abdulbaset M A Sulaiman, Chaitanya Madamanchi, Prachi P Agarwal
Arrhythmogenic cardiomyopathy (ACM) is a genetic disease characterized by replacement of ventricular myocardium with fibrofatty tissue, predisposing the patient to ventricular arrhythmias and/or sudden cardiac death. Most cases of ACM are associated with pathogenic variants in genes that encode desmosomal proteins, an important cell-to-cell adhesion complex present in both the heart and skin tissue. Although ACM was first described as a disease predominantly of the right ventricle, it is now acknowledged that it can also primarily involve the left ventricle or both ventricles...
April 2024: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://read.qxmd.com/read/38512549/metabolomics-approach-to-explore-bioactive-natural-products-derived-from-plant-root-associated-streptomyces
#9
JOURNAL ARTICLE
Ekrem Kum, Ebru İnce
Streptomyces, a prominent genus within the Actinomycetota phylum, is responsible for over 60% of clinically relevant antibiotics. Streptomyces strains inhabiting plant roots possess the potential to synthesize bioactive natural products, conferring defense and resilience to plants against pathogenic microorganisms. However, this potential remains largely unexplored. This study aims to screen for bioactive metabolites produced by Streptomyces strains in the plant rhizosphere.Six Streptomyces isolates were cultivated using three modified media to induce the production of diverse metabolites, employing the One Strain Many Compounds (OSMAC) approach...
March 21, 2024: Applied Biochemistry and Biotechnology
https://read.qxmd.com/read/38511308/effect-of-intermittent-oro-esophageal-tube-feeding-in-bulbar-palsy-after-ischemic-stroke-a-randomized-controlled-study
#10
JOURNAL ARTICLE
Hongji Zeng, Weijia Zhao, Junfa Wu, Jihong Wei, Heping Li, Liugen Wang, Xi Zeng
BACKGROUND: Nasogastric tube feeding (NG) has been widely used in patients with bulbar palsy after ischemic stroke but is associated with a significant risk of complications including malnutrition and pneumonia. Intermittent oro-esophageal tube feeding (IOE) can help alleviate these concerns. This study explored the clinical effect of IOE versus NG on nutritional status, swallowing function, stroke-associated pneumonia, and depression in patients with bulbar palsy after ischemic stroke...
March 21, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38510095/reversed-gore-excluder-conformable-main-body-as-a-conduit-between-branched-stent-graft-limb-common-iliac-artery-and-renal-artery
#11
JOURNAL ARTICLE
Pekka-Sakari Aho, Patrick Björkman, Maarit Venermo
Renal artery access might not always be achieved due to anatomical reasons during the deployment of a branched stent graft in thoracoabdominal or juxtarenal abdominal aortic aneurysms. Renal perfusion is maintained through the aneurysm sac until the iliac limbs are deployed. To preserve renal perfusion, a branched iliac limb would be needed. Such limbs with a side branch, a narrow (12-14 mm) proximal end, and a wide (16-20 mm) distal end are not commercially available. Due to the nature of their deployment mechanism, Gore Excluder distal limbs (W...
June 2024: Journal of Vascular Surgery Cases and Innovative Techniques
https://read.qxmd.com/read/38509787/effects-of-melatonin-against-experimentally-induced-apical-periodontitis-in-rats
#12
JOURNAL ARTICLE
D Kırmızı, A Ö Sehirli, S Sayiner, K Orhan, A Sebai, U Aksoy
Apical periodontitis is an inflammatory condition resulting from microbial invasion in the root canal system, causing periapical tissue destruction and bone resorption. This study investigated melatonin's effects, known for its antioxidant and anti-inflammatory properties, on experimentally induced apical periodontitis in rats. Three groups of rats were studied: control, apical periodontitis and apical periodontitis with melatonin treatment. Proinflammatory cytokines and enzyme levels in blood serum were measured, and micro-CT analysis assessed bone resorption...
March 21, 2024: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://read.qxmd.com/read/38507253/a-comprehensive-investigation-of-the-performance-of-a-commercial-scintillator-system-for-applications-in-electron-flash-radiotherapy
#13
JOURNAL ARTICLE
Kevin Liu, Shannon Holmes, Emil Schüler, Sam Beddar
BACKGROUND: Dosimetry in ultra-high dose rate (UHDR) beamlines is significantly challenged by limitations in real-time monitoring and accurate measurement of beam output, beam parameters, and delivered doses using conventional radiation detectors, which exhibit dependencies in ultra-high dose-rate (UHDR) and high dose-per-pulse (DPP) beamline conditions. PURPOSE: In this study, we characterized the response of the Exradin W2 plastic scintillator (Standard Imaging, Inc...
March 20, 2024: Medical Physics
https://read.qxmd.com/read/38499709/mapping-of-the-central-sulcus-using-non-invasive-ultra-high-density-brain-recordings
#14
JOURNAL ARTICLE
Leonhard Schreiner, Michael Jordan, Sebastian Sieghartsleitner, Christoph Kapeller, Harald Pretl, Kyousuke Kamada, Priscella Asman, Nuri F Ince, Kai J Miller, Christoph Guger
Brain mapping is vital in understanding the brain's functional organization. Electroencephalography (EEG) is one of the most widely used brain mapping approaches, primarily because it is non-invasive, inexpensive, straightforward, and effective. Increasing the electrode density in EEG systems provides more neural information and can thereby enable more detailed and nuanced mapping procedures. Here, we show that the central sulcus can be clearly delineated using a novel ultra-high-density EEG system (uHD EEG) and somatosensory evoked potentials (SSEPs)...
March 19, 2024: Scientific Reports
https://read.qxmd.com/read/38499589/the-microcirculation-in-the-first-days-of-icu-admission-in-critically-ill-covid-19-patients-is-influenced-by-severity-of-disease
#15
JOURNAL ARTICLE
Fleur Brouwer, Can Ince, Jiska Pols, Zühre Uz, Matthias Peter Hilty, Mendi Sesmu Arbous
The objective of this study was to investigate the relationship between sublingual microcirculatory parameters and the severity of the disease in critically ill coronavirus disease 2019 (COVID-19) patients in the initial period of Intensive Care Unit (ICU) admission in a phase of the COVID-19 pandemic where patients were being treated with anti-inflammatory medication. In total, 35 critically ill COVID-19 patients were included. Twenty-one critically ill COVID-19 patients with a Sequential Organ Failure Assessment (SOFA) score below or equal to 7 were compared to 14 critically ill COVID-19 patients with a SOFA score exceeding 7...
March 18, 2024: Scientific Reports
https://read.qxmd.com/read/38496160/laparoscopic-management-of-inguinal-hernia-a-systematic-review-and-updated-network-meta-analysis-of-randomized-controlled-trials
#16
REVIEW
Hadeel Almutairi, Reem S Alshammari, Majed J Alharbi, Dana M Althobaiti, Raghad S Alghamdi, Samar Alsamiri, Sara W Mawash, Duaa A Ahmed, Abdulrahman A Alamoudi, Fai Y Arif, Fatimah M Albrahim, Mohammed Alfehaid, Haneen W Alanzy
Various surgical approaches for inguinal hernia repair have been outlined in medical literature. In most cases, these lesions are repaired by general surgeons. A variety of surgical techniques for the treatment of inguinal hernias have been documented in the medical literature. In 2018, the European Hernia Society (EHS) recommended laparo-endoscopic repair as a preferred approach for adults. This method involves a combination of laparoscopic and endoscopic techniques for hernia repair. The goal of this systematic review is to conduct a thorough examination of the total extraperitoneal vs...
February 2024: Curēus
https://read.qxmd.com/read/38488899/assessment-and-validation-of-glottic-motion-using-cone-beam-ct-and-real-time-cine-mri
#17
JOURNAL ARTICLE
Seok-Joo Chun, Jaeman Son, Seonghee Kang, Chang Heon Choi, Jung-In Kim, Young-Il Kim, Joo Ho Lee, Jin Ho Kim, Hong-Gyun Wu
PURPOSE: This study aimed to assess the margin for the planning target volume (PTV) using the Van Herk formula. We then validated the proposed margin by real-time magnetic resonance imaging (MRI). METHODS: An analysis of cone-beam computed tomography (CBCT) data from early glottic cancer patients was performed to evaluate organ motion. Deformed clinical target volumes (CTV) after rigid registration were acquired using the Velocity program (Varian Medical Systems, Palo Alto, CA, USA)...
March 15, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38488844/patient-centered-approaches-for-designing-destigmatizing-sexual-pain-related-web-based-platforms-qualitative-study
#18
JOURNAL ARTICLE
Abdul-Fatawu Abdulai, Hasti Naghdali, Heather Noga, Paul J Yong
BACKGROUND: Sexual pain is a common but neglected disorder that affects approximately 3% to 18% of women and an unmeasured number of gender-diverse people worldwide. Despite its wide prevalence, many people feel reluctant to visit conventional health care services or disclose their symptoms due to the fear of stigmatization. To alleviate this stigma, various web-based interventions have been developed to complement and, in some cases, replace conventional sexual health interventions. However, the way these web-based interventions are developed could inadvertently reproduce, perpetuate, or exacerbate stigma among end user patients...
March 15, 2024: JMIR Formative Research
https://read.qxmd.com/read/38488839/methods-and-annotated-data-sets-used-to-predict-the-gender-and-age-of-twitter-users-scoping-review
#19
REVIEW
Karen O'Connor, Su Golder, Davy Weissenbacher, Ari Z Klein, Arjun Magge, Graciela Gonzalez-Hernandez
BACKGROUND: Patient health data collected from a variety of nontraditional resources, commonly referred to as real-world data, can be a key information source for health and social science research. Social media platforms, such as Twitter (Twitter, Inc), offer vast amounts of real-world data. An important aspect of incorporating social media data in scientific research is identifying the demographic characteristics of the users who posted those data. Age and gender are considered key demographics for assessing the representativeness of the sample and enable researchers to study subgroups and disparities effectively...
March 15, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38484958/phenotypic-and-molecular-characterization-of-multi-drug-resistant-klebsiella-spp-isolates-recovered-from-clinical-settings
#20
JOURNAL ARTICLE
Hassan Diab, Kelven Rahy, Tamima Jisr, Mira El Chaar, Edmond Abboud, Sima Tokajian
Klebsiella pneumoniae is a Gram-negative bacterium that colonizes the gastrointestinal tract and nasopharynx with many being linked to nosocomial infections. Extended-spectrum β-lactamases (ESBL)-producing and carbapenem-resistant K. pneumoniae is recognized by the World Health Organization (WHO) as a critical public health concern. In this study, whole-genome sequencing (WGS) - based analysis was performed to understand the molecular epidemiology of multi-drug resistant Klebsiella spp. clinical isolates...
March 12, 2024: Infection, Genetics and Evolution
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